Targeting Notch signaling pathway in cancer: Clinical development advances and challenges von TAKEBE, Naoko, NGUYEN, Dat, YANG, Sherry X

Volltext

New insights on PI3K/AKT pathway alterations and clinical outcomes in breast cancer von Yang, Sherry X, Polley, Eric, Lipkowitz, Stanley

Volltext

DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors von Laranjeira, Angelo B. A., Hollingshead, Melinda G., Nguyen, Dat, Kinders, Robert J., Doroshow, James H., Yang, Sherry X.

Volltext

The VEGF Inhibitor Axitinib Has Limited Effectiveness as a Therapy for Adrenocortical Cancer von O'Sullivan, Ciara, Edgerly, Maureen, Velarde, Margarita, Wilkerson, Julia, Venkatesan, Aradhana M, Pittaluga, Stefania, Yang, Sherry X, Nguyen, Dat, Balasubramaniam, Sanjeeve, Fojo, Tito

Volltext

Antiangiogenic and Antitumor Effects of Bevacizumab in Patients With Inflammatory and Locally Advanced Breast Cancer von WEDAM, Suparna Bonthala, LOW, Jennifer A, PLEHN, Jonathan, DOSHI, Arpi, THOMASSON, Dave, MCCARTHY, Nicole, KOEPPEN, Hartmut, SHERMAN, Mark, ZUJEWSKI, Joanne, CAMPHAUSEN, Kevin, CHEN, Helen, SWAIN, Sandra M, YANG, Sherry X, CHOW, Catherine K, CHOYKE, Peter, DANFORTH, David, HEWITT, Stephen M, BERMAN, Arlene, STEINBERG, Seth M, LIEWEHR, David J

Volltext

Locoregional tumor burden and risk of mortality in metastatic breast cancer von Yang, Sherry X., Hewitt, Stephen M., Yu, John

Volltext

Phase II Trial of Ixabepilone, an Epothilone B Analog, in Patients With Metastatic Breast Cancer Previously Untreated With Taxanes von DENDULURI, Neelima, LOW, Jennifer A, LEE, James J, BERMAN, Arlene W, WALSHE, Janice M, VATAS, Ujala, CHOW, Catherine K, STEINBERG, Seth M, YANG, Sherry X, SWAIN, Sandra M

Volltext

TET2 and DNMT3A mutations and exceptional response to 4 '-thio-2 '-deoxycytidine in human solid tumor models von Yang, Sherry X., Hollingshead, Melinda, Rubinstein, Larry, Nguyen, Dat, Larenjeira, Angelo B. A., Kinders, Robert J., Difilippantonio, Michael, Doroshow, James H.

Volltext

Upregulation of TET2 and Resistance to DNA Methyltransferase (DNMT) Inhibitors in DNMT1 -Deleted Cancer Cells von Laranjeira, Angelo B A, Nguyen, Dat, Pelosof, Lorraine C, Doroshow, James H, Yang, Sherry X

Volltext

Development and Validation of a Nomogram for Early Detection of Malignant Gallbladder Lesions von Chen, Mingyu, Cao, Jiasheng, Bai, Yang, Tong, Chenhao, Lin, Jian, Jindal, Vishal, Barchi, Leandro Cardoso, Nadalin, Silvio, Yang, Sherry X, Pesce, Antonio, Panaro, Fabrizio, Ariche, Arie, Kai, Keita, Memeo, Riccardo, Bekaii-Saab, Tanios, Cai, Xiujun

Volltext

Multiplexed Cell Signaling Analysis of Human Breast Cancer Applications for Personalized Therapy von Wulfkuhle, Julia D, Speer, Runa, Pierobon, Mariaelena, Laird, Julie, Espina, Virginia, Deng, Jianghong, Mammano, Enzo, Yang, Sherry X, Swain, Sandra M, Nitti, Donato, Esserman, Laura J, Belluco, Claudio, Liotta, Lance A, Petricoin, Emanuel F

Volltext

Phase II Clinical Trial of Ixabepilone (BMS-247550), an Epothilone B Analog, in Metastatic and Locally Advanced Breast Cancer von LOW, Jennifer A, WEDAM, Suparna B, SWAIN, Sandra M, LEE, James J, BERMAN, Arlene W, BRUFSKY, Adam, YANG, Sherry X, PORUCHYNSKY, Marianne S, STEINBERG, Seth M, MANNAN, Nitin, FOJO, Tito

Volltext

Akt Phosphorylation at Ser473 Predicts Benefit of Paclitaxel Chemotherapy in Node-Positive Breast Cancer von YANG, Sherry X, COSTANTINO, Joseph P, KIM, Chungyeul, MAMOUNAS, Eleftherios P, NGUYEN, Dat, JEONG, Jong-Hyeon, WOLMARK, Norman, KIDWELL, Kelley, PAIK, Soonmyung, SWAIN, Sandra M

Volltext

DNA methyltransferase inhibitor, zebularine, delays tumor growth and induces apoptosis in a genetically engineered mouse model of breast cancer von Chen, Min, Shabashvili, Daniel, Nawab, Akbar, Yang, Sherry X, Dyer, Lisa M, Brown, Kevin D, Hollingshead, Melinda, Hunter, Kent W, Kaye, Frederic J, Hochwald, Steven N, Marquez, Victor E, Steeg, Patricia, Zajac-Kaye, Maria

Volltext

Designing Phase 0 Cancer Clinical Trials von Murgo, Anthony J, Kummar, Shivaani, Rubinstein, Larry, Gutierrez, Martin, Collins, Jerry, Kinders, Robert, Parchment, Ralph E, Ji, Jiuping, Steinberg, Seth M, Yang, Sherry X, Hollingshead, Melinda, Chen, Alice, Helman, Lee, Wiltrout, Robert, Tomaszewski, Joseph E, Doroshow, James H

Volltext

Systemic treatment and radiotherapy, breast cancer subtypes, and survival after long-term clinical follow-up von Yang, Sherry X., Polley, Eric C.

Volltext

Poly(ADP-ribose) polymerase inhibition enhances p53-dependent and -independent DNA damage responses induced by DNA damaging agent von Nguyen, Diana, Zajac-Kaye, Maria, Rubinstein, Larry, Voeller, Donna, Tomaszewski, Joseph E., Kummar, Shivaani, Chen, Alice P., Pommier, Yves, Doroshow, James H., Yang, Sherry X.

Volltext

Phase I clinical trial of oral 2-methoxyestradiol, an antiangiogenic and apoptotic agent, in patients with solid tumors von Dahut, William L., Lakhani, Nehal J., Gulley, James L., Arlen, Philip M., Kohn, Elise C., Kotz, Herbert, McNally, Debbie, Parr, Allyson, Nguyen, Diana, Yang, Sherry X., Steinberg, Seth M., Venitz, Jürgen, Sparreboom, Alex, Figg, II, William

Volltext

Association of Independent Prognostic Factors and Treatment Modality With Survival and Recurrence Outcomes in Breast Cancer von Nguyen, Dat, Yu, John, Reinhold, William C., Yang, Sherry X.

Volltext

Evaluation of Lymphangiogenic Factors, Vascular Endothelial Growth Factor D and E-Cadherin in Distinguishing Inflammatory From Locally Advanced Breast Cancer von Levine, Paul H, Portera, Chia C, Hoffman, Heather J, Yang, Sherry X, Takikita, Mikiko, Duong, Quyen N, Hewitt, Stephen M, Swain, Sandra M

Volltext