Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA von Jung, Hea-Jin, Coffinier, Catherine, Choe, Youngshik, Beigneux, Anne P, Davies, Brandon S. J, Yang, Shao H, Barnes, Richard H. II, Hong, Janet, Sun, Tao, Pleasure, Samuel J, Young, Stephen G, Fong, Loren G

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Protein Farnesyltransferase Inhibitor Ameliorates Disease in a Mouse Model of Progeria von Fong, Loren G, Frost, David, Meta, Margarita, Qiao, Xin, Yang, Shao H, Coffinier, Catherine, Young, Stephen G

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Blocking Protein Farnesyltransferase Improves Nuclear Shape in Fibroblasts from Humans with Progeroid Syndromes von Toth, Julia I., Yang, Shao H., Qiao, Xin, Beigneux, Anne P., Gelb, Michael H., Moulson, Casey L., Miner, Jeffrey H., Young, Stephen G., Fong, Loren G., Havel, Richard J.

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Blocking Protein Farnesyltransferase Improves Nuclear Blebbing in Mouse Fibroblasts with a Targeted Hutchinson-Gilford Progeria Syndrome Mutation von Yang, Shao H., Bergo, Martin O., Toth, Julia I., Qiao, Xin, Hu, Yan, Sandoval, Salemiz, Meta, Margarita, Bendale, Pravin, Gelb, Michael H., Young, Stephen G., Fong, Loren G., Steinberg, Daniel

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The posttranslational processing of prelamin A and disease von Davies, Brandon S J, Fong, Loren G, Yang, Shao H, Coffinier, Catherine, Young, Stephen G

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Prelamin A Farnesylation and Progeroid Syndromes von Young, Stephen G., Meta, Margarita, Yang, Shao H., Fong, Loren G.

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Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer von Liu, Meng, Sjogren, Anna-Karin M, Karlsson, Christin, Ibrahim, Mohamed X, Andersson, Karin M.E, Olofsson, Frida J, Wahlstrom, Annika M, Dalin, Martin, Yu, Huiming, Chen, Zhenggang, Yang, Shao H, Young, Stephen G, Bergo, Martin O

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Heterozygosity for Lmna Deficiency Eliminates the Progeria-Like Phenotypes in Zmpste24-Deficient Mice von Fong, Loren G, Ng, Jennifer K, Meta, Margarita, Coté, Nathan, Yang, Shao H, Stewart, Colin L, Sullivan, Terry, Burghardt, Andrew, Majumdar, Sharmila, Reue, Karen, Bergo, Martin O, Young, Stephen G

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New Lmna knock-in mice provide a molecular mechanism for the 'segmental aging' in Hutchinson-Gilford progeria syndrome von Jung, Hea-Jin, Tu, Yiping, Yang, Shao H, Tatar, Angelica, Nobumori, Chika, Wu, Daniel, Young, Stephen G, Fong, Loren G

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Assessing the efficacy of protein farnesyltransferase inhibitors in mouse models of progeria von Yang, Shao H., Chang, Sandy Y., Andres, Douglas A., Spielmann, H. Peter, Young, Stephen G., Fong, Loren G.

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Modulation of LMNA splicing as a strategy to treat prelamin A diseases von Lee, John M, Nobumori, Chika, Tu, Yiping, Choi, Catherine, Yang, Shao H, Jung, Hea-Jin, Vickers, Timothy A, Rigo, Frank, Bennett, C Frank, Young, Stephen G, Fong, Loren G

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Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24 von Chang, Sandy Y., Hudon-Miller, Sarah E., Yang, Shao H., Jung, Hea-Jin, Lee, John M., Farber, Emily, Subramanian, Thangaiah, Andres, Douglas A., Spielmann, H.Peter, Hrycyna, Christine A., Young, Stephen G., Fong, Loren G.

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Severe hepatocellular disease in mice lacking one or both CaaX prenyltransferases[S] von Yang, Shao H., Chang, Sandy Y., Tu, Yiping, Lawson, Gregory W., Bergo, Martin O., Fong, Loren G., Young, Stephen G.

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Are B-type lamins essential in all mammalian cells? von Yang, Shao H., Jung, Hea-Jin, Coffinier, Catherine, Fong, Loren G., Young, Stephen G.

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N-Myristoyltransferase 1 Is Essential in Early Mouse Development von Yang, Shao H., Shrivastav, Anuraag, Kosinski, Cynthia, Sharma, Rajendra K., Chen, Miao-Hsueh, Berthiaume, Luc G., Peters, Luanne L., Chuang, Pao-Tien, Young, Stephen G., Bergo, Martin O.

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Eliminating the Synthesis of Mature Lamin A Reduces Disease Phenotypes in Mice Carrying a Hutchinson-Gilford Progeria Syndrome Allele von Yang, Shao H., Qiao, Xin, Farber, Emily, Chang, Sandy Y., Fong, Loren G., Young, Stephen G.

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A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation von Yang, Shao H, Meta, Margarita, Qiao, Xin, Frost, David, Bauch, Joy, Coffinier, Catherine, Majumdar, Sharmila, Bergo, Martin O, Young, Stephen G, Fong, Loren G

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An absence of both lamin B1 and lamin B2 in keratinocytes has no effect on cell proliferation or the development of skin and hair von YANG, Shao H, CHANG, Sandy Y, LIYA YIN, YIPING TU, YAN HU, YUKO YOSHINAGA, DE JONG, Pieter J, FONG, Loren G, YOUNG, Stephen G

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An Absence of Nuclear Lamins in Keratinocytes Leads to Ichthyosis, Defective Epidermal Barrier Function, and Intrusion of Nuclear Membranes and Endoplasmic Reticulum into the Nucle... von Jung, Hea-Jin, Tatar, Angelica, Tu, Yiping, Nobumori, Chika, Yang, Shao H., Goulbourne, Chris N., Herrmann, Harald, Fong, Loren G., Young, Stephen G.

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Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated von Yang, Shao H, Andres, Douglas A, Spielmann, H Peter, Young, Stephen G, Fong, Loren G

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