Efficacy and safety of a single dose of casirivimab and imdevimab for the prevention of COVID-19 over an 8-month period: a randomised, double-blind, placebo-controlled trial von Herman, Gary A, O'Brien, Meagan P, Forleo-Neto, Eduardo, Sarkar, Neena, Isa, Flonza, Hou, Peijie, Chan, Kuo-Chen, Bar, Katharine J, Barnabas, Ruanne V, Barouch, Dan H, Cohen, Myron S, Hurt, Christopher B, Burwen, Dale R, Marovich, Mary A, Musser, Bret J, Davis, John D, Turner, Kenneth C, Mahmood, Adnan, Hooper, Andrea T, Hamilton, Jennifer D, Parrino, Janie, Subramaniam, Danise, Baum, Alina, Kyratsous, Christos A, DiCioccio, A Thomas, Stahl, Neil, Braunstein, Ned, Yancopoulos, George D, Weinreich, David M

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RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes von Xin, Yurong, Kim, Jinrang, Okamoto, Haruka, Ni, Min, Wei, Yi, Adler, Christina, Murphy, Andrew J., Yancopoulos, George D., Lin, Calvin, Gromada, Jesper

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Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies von Baum, Alina, Fulton, Benjamin O, Wloga, Elzbieta, Copin, Richard, Pascal, Kristen E, Russo, Vincenzo, Giordano, Stephanie, Lanza, Kathryn, Negron, Nicole, Ni, Min, Wei, Yi, Atwal, Gurinder S, Murphy, Andrew J, Stahl, Neil, Yancopoulos, George D, Kyratsous, Christos A

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Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal Polyposis: A Randomized Clinical Trial von Bachert, Claus, Mannent, Leda, Naclerio, Robert M, Mullol, Joaquim, Ferguson, Berrylin J, Gevaert, Philippe, Hellings, Peter, Jiao, Lixia, Wang, Lin, Evans, Robert R, Pirozzi, Gianluca, Graham, Neil M, Swanson, Brian, Hamilton, Jennifer D, Radin, Allen, Gandhi, Namita A, Stahl, Neil, Yancopoulos, George D, Sutherland, E. Rand

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REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters von Baum, Alina, Ajithdoss, Dharani, Copin, Richard, Zhou, Anbo, Lanza, Kathryn, Negron, Nicole, Ni, Min, Wei, Yi, Mohammadi, Kusha, Musser, Bret, Atwal, Gurinder S, Oyejide, Adelekan, Goez-Gazi, Yenny, Dutton, John, Clemmons, Elizabeth, Staples, Hilary M, Bartley, Carmen, Klaffke, Benjamin, Alfson, Kendra, Gazi, Michal, Gonzalez, Olga, Dick, Jr, Edward, Carrion, Jr, Ricardo, Pessaint, Laurent, Porto, Maciel, Cook, Anthony, Brown, Renita, Ali, Vaneesha, Greenhouse, Jack, Taylor, Tammy, Andersen, Hanne, Lewis, Mark G, Stahl, Neil, Murphy, Andrew J, Yancopoulos, George D, Kyratsous, Christos A

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Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised d... von Wenzel, Sally, Prof, Castro, Mario, MD, Corren, Jonathan, MD, Maspero, Jorge, MD, Wang, Lin, PhD, Zhang, Bingzhi, PhD, Pirozzi, Gianluca, MD, Sutherland, E Rand, MD, Evans, Robert R, PharmD, Joish, Vijay N, PhD, Eckert, Laurent, PhD, Graham, Neil M H, MD, Stahl, Neil, PhD, Yancopoulos, George D, MD, Louis-Tisserand, Mariana, MD, Teper, Ariel, MD

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Cemiplimab in locally advanced basal cell carcinoma after hedgehog inhibitor therapy: an open-label, multi-centre, single-arm, phase 2 trial von Stratigos, Alexander J, Sekulic, Aleksandar, Peris, Ketty, Bechter, Oliver, Prey, Sorilla, Kaatz, Martin, Lewis, Karl D, Basset-Seguin, Nicole, Chang, Anne Lynn S, Dalle, Stèphane, Orland, Almudena Fernandez, Licitra, Lisa, Robert, Caroline, Ulrich, Claas, Hauschild, Axel, Migden, Michael R, Dummer, Reinhard, Li, Siyu, Yoo, Suk-Young, Mohan, Kosalai, Coates, Ebony, Jankovic, Vladimir, Fiaschi, Nathalie, Okoye, Emmanuel, Bassukas, Ioannis D, Loquai, Carmen, De Giorgi, Vincenzo, Eroglu, Zeynep, Gutzmer, Ralf, Ulrich, Jens, Puig, Susana, Seebach, Frank, Thurston, Gavin, Weinreich, David M, Yancopoulos, George D, Lowy, Israel, Bowler, Timothy, Fury, Matthew G

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Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma von Rabe, Klaus F, Nair, Parameswaran, Brusselle, Guy, Maspero, Jorge F, Castro, Mario, Sher, Lawrence, Zhu, Hongjie, Hamilton, Jennifer D, Swanson, Brian N, Khan, Asif, Chao, Jingdong, Staudinger, Heribert, Pirozzi, Gianluca, Antoni, Christian, Amin, Nikhil, Ruddy, Marcella, Akinlade, Bolanle, Graham, Neil M.H, Stahl, Neil, Yancopoulos, George D, Teper, Ariel

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Targeting key proximal drivers of type 2 inflammation in disease von Gandhi, Namita A., Bennett, Brandy L., Graham, Neil M. H., Pirozzi, Gianluca, Stahl, Neil, Yancopoulos, George D.

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Cemiplimab monotherapy for first-line treatment of advanced non-small-cell lung cancer with PD-L1 of at least 50%: a multicentre, open-label, global, phase 3, randomised, controlle... von Sezer, Ahmet, Kilickap, Saadettin, Gümüş, Mahmut, Bondarenko, Igor, Özgüroğlu, Mustafa, Gogishvili, Miranda, Turk, Haci M, Cicin, Irfan, Bentsion, Dmitry, Gladkov, Oleg, Clingan, Philip, Sriuranpong, Virote, Rizvi, Naiyer, Gao, Bo, Li, Siyu, Lee, Sue, McGuire, Kristina, Chen, Chieh-I, Makharadze, Tamta, Paydas, Semra, Nechaeva, Marina, Seebach, Frank, Weinreich, David M, Yancopoulos, George D, Gullo, Giuseppe, Lowy, Israel, Rietschel, Petra

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Cemiplimab plus chemotherapy versus chemotherapy alone in non-small cell lung cancer: a randomized, controlled, double-blind phase 3 trial von Gogishvili, Miranda, Melkadze, Tamar, Makharadze, Tamta, Giorgadze, Davit, Dvorkin, Mikhail, Penkov, Konstantin, Laktionov, Konstantin, Nemsadze, Gia, Nechaeva, Marina, Rozhkova, Irina, Kalinka, Ewa, Gessner, Christian, Moreno-Jaime, Brizio, Passalacqua, Rodolfo, Li, Siyu, McGuire, Kristina, Kaul, Manika, Paccaly, Anne, Quek, Ruben G. W., Gao, Bo, Seebach, Frank, Weinreich, David M., Yancopoulos, George D., Lowy, Israel, Gullo, Giuseppe, Rietschel, Petra

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Efficacy and Safety of Itepekimab in Patients with Moderate-to-Severe Asthma von Wechsler, Michael E, Ruddy, Marcella K, Pavord, Ian D, Israel, Elliot, Rabe, Klaus F, Ford, Linda B, Maspero, Jorge F, Abdulai, Raolat M, Hu, Chih-Chi, Martincova, Renata, Jessel, Andreas, Nivens, Michael C, Amin, Nikhil, Weinreich, David M, Yancopoulos, George D, Goulaouic, Helene

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ANGPTL8/Betatrophin Does Not Control Pancreatic Beta Cell Expansion von Gusarova, Viktoria, Alexa, Corey A., Na, Erqian, Stevis, Panayiotis E., Xin, Yurong, Bonner-Weir, Susan, Cohen, Jonathan C., Hobbs, Helen H., Murphy, Andrew J., Yancopoulos, George D., Gromada, Jesper

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Evinacumab for Homozygous Familial Hypercholesterolemia von Raal, Frederick J, Rosenson, Robert S, Reeskamp, Laurens F, Hovingh, G. Kees, Kastelein, John J.P, Rubba, Paolo, Ali, Shazia, Banerjee, Poulabi, Chan, Kuo-Chen, Gipe, Daniel A, Khilla, Nagwa, Pordy, Robert, Weinreich, David M, Yancopoulos, George D, Zhang, Yi, Gaudet, Daniel

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ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia von Gaudet, Daniel, Gipe, Daniel A, Pordy, Robert, Ahmad, Zahid, Cuchel, Marina, Shah, Prediman K, Chyu, Kuang-Yuh, Sasiela, William J, Chan, Kuo-Chen, Brisson, Diane, Khoury, Etienne, Banerjee, Poulabi, Gusarova, Viktoria, Gromada, Jesper, Stahl, Neil, Yancopoulos, George D, Hovingh, G. Kees

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Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging p... von Thaçi, Diamant, Prof, Simpson, Eric L, MD, Beck, Lisa A, Prof, Bieber, Thomas, Prof, Blauvelt, Andrew, MD, Papp, Kim, MD, Soong, Weily, MD, Worm, Margitta, Univ-Prof, Szepietowski, Jacek C, Prof, Sofen, Howard, MD, Kawashima, Makoto, Prof, Wu, Richard, PhD, Weinstein, Steven P, MD, Graham, Neil M H, MD, Pirozzi, Gianluca, MD, Teper, Ariel, MD, Sutherland, E Rand, MD, Mastey, Vera, MS, Stahl, Neil, PhD, Yancopoulos, George D, MD, Ardeleanu, Marius, MD

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Dual blockade of IL‐4 and IL‐13 with dupilumab, an IL‐4Rα antibody, is required to broadly inhibit type 2 inflammation von Le Floc’h, Audrey, Allinne, Jeanne, Nagashima, Kirsten, Scott, George, Birchard, Dylan, Asrat, Seblewongel, Bai, Yu, Lim, Wei Keat, Martin, Joel, Huang, Tammy, Potocky, Terra B., Kim, Jee H., Rafique, Ashique, Papadopoulos, Nicholas J., Stahl, Neil, Yancopoulos, George D., Murphy, Andrew J., Sleeman, Matthew A., Orengo, Jamie M.

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Intravitreal Aflibercept for Diabetic Macular Edema von Korobelnik, Jean-François, MD, Do, Diana V., MD, Schmidt-Erfurth, Ursula, MD, Boyer, David S., MD, Holz, Frank G., MD, Heier, Jeffrey S., MD, Midena, Edoardo, MD, Kaiser, Peter K., MD, Terasaki, Hiroko, MD, Marcus, Dennis M., MD, Nguyen, Quan D., MD, Jaffe, Glenn J., MD, Slakter, Jason S., MD, Simader, Christian, MD, Soo, Yuhwen, PhD, Schmelter, Thomas, PhD, Yancopoulos, George D., MD, PhD, Stahl, Neil, PhD, Vitti, Robert, MD, Berliner, Alyson J., MD, PhD, Zeitz, Oliver, MD, Metzig, Carola, MD, Brown, David M., MD

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Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis von Hamilton, Jennifer D., PhD, Suárez-Fariñas, Mayte, PhD, Dhingra, Nikhil, BS, Cardinale, Irma, MSc, Li, Xuan, PhD, Kostic, Ana, PhD, Ming, Jeffrey E., MD, PhD, Radin, Allen R., MD, Krueger, James G., MD, Graham, Neil, MD, Yancopoulos, George D., MD, PhD, Pirozzi, Gianluca, MD, PhD, Guttman-Yassky, Emma, MD, PhD

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Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis von Dellon, Evan S., Rothenberg, Marc E., Collins, Margaret H., Hirano, Ikuo, Chehade, Mirna, Bredenoord, Albert J., Lucendo, Alfredo J., Spergel, Jonathan M., Aceves, Seema, Sun, Xian, Kosloski, Matthew P., Kamal, Mohamed A., Hamilton, Jennifer D., Beazley, Bethany, McCann, Eilish, Patel, Kiran, Mannent, Leda P., Laws, Elizabeth, Akinlade, Bolanle, Amin, Nikhil, Lim, Wei Keat, Wipperman, Matthew F., Ruddy, Marcella, Patel, Naimish, Weinreich, David R., Yancopoulos, George D., Shumel, Brad, Maloney, Jennifer, Giannelou, Angeliki, Shabbir, Arsalan

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