Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy von Gide, Tuba N., Quek, Camelia, Menzies, Alexander M., Tasker, Annie T., Shang, Ping, Holst, Jeff, Madore, Jason, Lim, Su Yin, Velickovic, Rebecca, Wongchenko, Matthew, Yan, Yibing, Lo, Serigne, Carlino, Matteo S., Guminski, Alexander, Saw, Robyn P.M., Pang, Angel, McGuire, Helen M., Palendira, Umaimainthan, Thompson, John F., Rizos, Helen, Silva, Ines Pires da, Batten, Marcel, Scolyer, Richard A., Long, Georgina V., Wilmott, James S.

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Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients von Sullivan, Ryan J., Hamid, Omid, Gonzalez, Rene, Infante, Jeffrey R., Patel, Manish R., Hodi, F. Stephen, Lewis, Karl D., Tawbi, Hussein A., Hernandez, Genevive, Wongchenko, Matthew J., Chang, YiMeng, Roberts, Louise, Ballinger, Marcus, Yan, Yibing, Cha, Edward, Hwu, Patrick

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Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors von Wilson, Timothy R., Fridlyand, Jane, Yan, Yibing, Penuel, Elicia, Burton, Luciana, Chan, Emily, Peng, Jing, Lin, Eva, Wang, Yulei, Sosman, Jeff, Ribas, Antoni, Li, Jiang, Moffat, John, Sutherlin, Daniel P., Koeppen, Hartmut, Merchant, Mark, Neve, Richard, Settleman, Jeff

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Tumour gene expression signature in primary melanoma predicts long-term outcomes von Garg, Manik, Couturier, Dominique-Laurent, Nsengimana, Jérémie, Fonseca, Nuno A., Wongchenko, Matthew, Yan, Yibing, Lauss, Martin, Jönsson, Göran B., Newton-Bishop, Julia, Parkinson, Christine, Middleton, Mark R., Bishop, D. Timothy, McDonald, Sarah, Stefanos, Nikki, Tadross, John, Vergara, Ismael A., Lo, Serigne, Newell, Felicity, Wilmott, James S., Thompson, John F., Long, Georgina V., Scolyer, Richard A., Corrie, Pippa, Adams, David J., Brazma, Alvis, Rabbie, Roy

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The vessel density of the superficial retinal capillary plexus as a new biomarker in cerebral small vessel disease: an optical coherence tomography angiography study von Wang, Xiaojing, Wei, Qiang, Wu, Xingqi, Cao, Shanshan, Chen, Chen, Zhang, Jun, Yan, Yibing, Geng, Zhi, Tian, Yanghua, Wang, Kai

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Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure von Guler, Gulfem Dilek, Tindell, Charles Albert, Pitti, Robert, Wilson, Catherine, Nichols, Katrina, KaiWai Cheung, Tommy, Kim, Hyo-Jin, Wongchenko, Matthew, Yan, Yibing, Haley, Benjamin, Cuellar, Trinna, Webster, Joshua, Alag, Navneet, Hegde, Ganapati, Jackson, Erica, Nance, Tracy Leah, Giresi, Paul Garrett, Chen, Kuan-Bei, Liu, Jinfeng, Jhunjhunwala, Suchit, Settleman, Jeff, Stephan, Jean-Philippe, Arnott, David, Classon, Marie

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Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2 von Foster, Scott A., Whalen, Daniel M., Özen, Ayşegül, Wongchenko, Matthew J., Yin, JianPing, Yen, Ivana, Schaefer, Gabriele, Mayfield, John D., Chmielecki, Juliann, Stephens, Philip J., Albacker, Lee A., Yan, Yibing, Song, Kyung, Hatzivassiliou, Georgia, Eigenbrot, Charles, Yu, Christine, Shaw, Andrey S., Manning, Gerard, Skelton, Nicholas J., Hymowitz, Sarah G., Malek, Shiva

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Accelerated intermittent theta-burst stimulation broadly ameliorates symptoms and cognition in Alzheimer's disease: A randomized controlled trial von Wu, Xingqi, Ji, Gong-Jun, Geng, Zhi, Wang, Lu, Yan, Yibing, Wu, Yue, Xiao, Guixian, Gao, Liying, Wei, Qiang, Zhou, Shanshan, Wei, Ling, Tian, Yanghua, Wang, Kai

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Phase Ib study of the MEK inhibitor cobimetinib (GDC-0973) in combination with the PI3K inhibitor pictilisib (GDC-0941) in patients with advanced solid tumors von Shapiro, Geoffrey I., LoRusso, Patricia, Kwak, Eunice, Pandya, Susan, Rudin, Charles M., Kurkjian, Carla, Cleary, James M., Pilat, Mary Jo, Jones, Suzanne, de Crespigny, Alex, Fredrickson, Jill, Musib, Luna, Yan, Yibing, Wongchenko, Matthew, Hsieh, Hsin-Ju, Gates, Mary R., Chan, Iris T., Bendell, Johanna

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Repetitive transcranial magnetic stimulation in Alzheimer's disease: effects on neural and synaptic rehabilitation von Ji, Yi, Yang, Chaoyi, Pang, Xuerui, Yan, Yibing, Wu, Yue, Geng, Zhi, Hu, Wenjie, Hu, Panpan, Wu, Xingqi, Wang, Kai

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A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types von Wagle, Marie-Claire, Kirouac, Daniel, Klijn, Christiaan, Liu, Bonnie, Mahajan, Shilpi, Junttila, Melissa, Moffat, John, Merchant, Mark, Huw, Ling, Wongchenko, Matthew, Okrah, Kwame, Srinivasan, Shrividhya, Mounir, Zineb, Sumiyoshi, Teiko, Haverty, Peter M., Yauch, Robert L., Yan, Yibing, Kabbarah, Omar, Hampton, Garret, Amler, Lukas, Ramanujan, Saroja, Lackner, Mark R., Huang, Shih-Min A.

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Near-infrared light-mediated HMTNs@PMO-DOX/ICG@HA drug composite nanoparticles enable a synergistic combination of chemical and photothermal therapy for tumors von Cai, Xiaoqin, Wu, Nian, Song, Fangxiang, Luo, Honghuan, Li, Tingxian, Yan, Yibing, Li, Songye, Li, Yan

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Author Correction: Tumour gene expression signature in primary melanoma predicts long-term outcomes von Garg, Manik, Couturier, Dominique-Laurent, Nsengimana, Jérémie, Fonseca, Nuno A., Wongchenko, Matthew, Yan, Yibing, Lauss, Martin, Jönsson, Göran B., Newton-Bishop, Julia, Parkinson, Christine, Middleton, Mark R., Bishop, D. Timothy, McDonald, Sarah, Stefanos, Nikki, Tadross, John, Vergara, Ismael A., Lo, Serigne, Newell, Felicity, Wilmott, James S., Thompson, John F., Long, Georgina V., Scolyer, Richard A., Corrie, Pippa, Adams, David J., Brazma, Alvis, Rabbie, Roy

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Network quantification of EGFR signaling unveils potential for targeted combination therapy von Klinger, Bertram, Sieber, Anja, Fritsche‐Guenther, Raphaela, Witzel, Franziska, Berry, Leanne, Schumacher, Dirk, Yan, Yibing, Durek, Pawel, Merchant, Mark, Schäfer, Reinhold, Sers, Christine, Blüthgen, Nils

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Development and validation of a machine learning-based predictive model for assessing the 90-day prognostic outcome of patients with spontaneous intracerebral hemorrhage von Geng, Zhi, Yang, Chaoyi, Zhao, Ziye, Yan, Yibing, Guo, Tao, Liu, Chaofan, Wu, Aimei, Wu, Xingqi, Wei, Ling, Tian, Yanghua, Hu, Panpan, Wang, Kai

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A phase Ib open-label dose escalation study of the safety, pharmacokinetics, and pharmacodynamics of cobimetinib (GDC-0973) and ipatasertib (GDC-0068) in patients with locally adva... von Shapiro, Geoffrey I., LoRusso, Patricia, Cho, Daniel C., Musib, Luna, Yan, Yibing, Wongchenko, Matthew, Chang, Ilsung, Patel, Premal, Chan, Iris T., Sanabria-Bohorquez, Sandra, Meng, Raymond D., Bendell, Johanna C.

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Tumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer von Taraborrelli, Lucia, Şenbabaoğlu, Yasin, Wang, Lifen, Lim, Junghyun, Blake, Kerrigan, Kljavin, Noelyn, Gierke, Sarah, Scherl, Alexis, Ziai, James, McNamara, Erin, Owyong, Mark, Rao, Shilpa, Calviello, Aslihan Karabacak, Oreper, Daniel, Jhunjhunwala, Suchit, Argiles, Guillem, Bendell, Johanna, Kim, Tae Won, Ciardiello, Fortunato, Wongchenko, Matthew J., de Sauvage, Frederic J., de Sousa e Melo, Felipe, Yan, Yibing, West, Nathaniel R., Murthy, Aditya

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The Metalloprotease Kuzbanian (ADAM10) Mediates the Transactivation of EGF Receptor by G Protein-Coupled Receptors von Yan, Yibing, Shirakabe, Kyoko, Werb, Zena

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Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation von Long, Jason E., Wongchenko, Matthew J., Nickles, Dorothee, Chung, Wei-Jen, Wang, Bu-er, Riegler, Johannes, Li, Ji, Li, Qingling, Sandoval, Wendy, Eastham-Anderson, Jeff, Modrusan, Zora, Junttila, Teemu, Carano, Richard A. D., Foreman, Oded, Yan, Yibing, Junttila, Melissa R.

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Gene Expression Profiling in BRAF -Mutated Melanoma Reveals Patient Subgroups with Poor Outcomes to Vemurafenib That May Be Overcome by Cobimetinib Plus Vemurafenib von Wongchenko, Matthew J, McArthur, Grant A, Dréno, Brigitte, Larkin, James, Ascierto, Paolo A, Sosman, Jeffrey, Andries, Luc, Kockx, Mark, Hurst, Stephen D, Caro, Ivor, Rooney, Isabelle, Hegde, Priti S, Molinero, Luciana, Yue, Huibin, Chang, Ilsung, Amler, Lukas, Yan, Yibing, Ribas, Antoni

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