Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer von Russo, Mariangela, Misale, Sandra, Wei, Ge, Siravegna, Giulia, Crisafulli, Giovanni, Lazzari, Luca, Corti, Giorgio, Rospo, Giuseppe, Novara, Luca, Mussolin, Benedetta, Bartolini, Alice, Cam, Nicholas, Patel, Roopal, Yan, Shunqi, Shoemaker, Robert, Wild, Robert, Di Nicolantonio, Federica, Bianchi, Andrea Sartore, Li, Gang, Siena, Salvatore, Bardelli, Alberto

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Antitumor Activity of RXDX-105 in Multiple Cancer Types with RET Rearrangements or Mutations von Li, Gang G, Somwar, Romel, Joseph, James, Smith, Roger S, Hayashi, Takuo, Martin, Leenus, Franovic, Aleksandra, Schairer, Anni, Martin, Eric, Riely, Gregory J, Harris, Jason, Yan, Shunqi, Wei, Ge, Oliver, Jennifer W, Patel, Rupal, Multani, Pratik, Ladanyi, Marc, Drilon, Alexander

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Identification and structure–activity relationships of substituted pyridones as inhibitors of Pim-1 kinase von Cheney, I. Wayne, Yan, Shunqi, Appleby, Todd, Walker, Heli, Vo, Todd, Yao, Nanhua, Hamatake, Robert, Hong, Zhi, Wu, Jim Z.

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Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors von Yan, Shunqi, Appleby, Todd, Larson, Gary, Wu, Jim Z., Hamatake, Robert, Hong, Zhi, Yao, Nanhua

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Using Cyclooxygenase-2 Inhibitors as Molecular Platforms to Develop a New Class of Apoptosis-Inducing Agents von Zhu, Jiuxiang, Song, Xueqin, Lin, Ho-Pi, Young, Donn C., Yan, Shunqi, Marquez, Victor E., Chen, Ching-Shih

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Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: Convergence of structure-based drug design and X-ray crystallographic study von Yan, Shunqi, Appleby, Todd, Larson, Gary, Wu, Jim Z., Hamatake, Robert K., Hong, Zhi, Yao, Nanhua

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Isothiazoles as active-site inhibitors of HCV NS5B polymerase von Yan, Shunqi, Appleby, Todd, Gunic, Esmir, Shim, Jae Hoon, Tasu, Tania, Kim, Hongwoo, Rong, Frank, Chen, Huaming, Hamatake, Robert, Wu, Jim Z., Hong, Zhi, Yao, Nanhua

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Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation von Wang, Fang, Travins, Jeremy, DeLaBarre, Byron, Penard-Lacronique, Virginie, Schalm, Stefanie, Hansen, Erica, Straley, Kimberly, Kernytsky, Andrew, Liu, Wei, Gliser, Camelia, Yang, Hua, Gross, Stefan, Artin, Erin, Saada, Veronique, Mylonas, Elena, Quivoron, Cyril, Popovici-Muller, Janeta, Saunders, Jeffrey O., Salituro, Francesco G., Yan, Shunqi, Murray, Stuart, Wei, Wentao, Gao, Yi, Dang, Lenny, Dorsch, Marion, Agresta, Sam, Schenkein, David P., Biller, Scott A., Su, Shinsan M., de Botton, Stephane, Yen, Katharine E.

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Identification of isothiazole-4-carboxamidines derivatives as a novel class of allosteric MEK1 inhibitors von El Abdellaoui, Hassan, Varaprasad, Chamakura V.N.S., Barawkar, Dinesh, Chakravarty, Subrata, Maderna, Andreas, Tam, Robert, Chen, Huanming, Allan, Matt, Wu, Jim Z., Appleby, Todd, Yan, Shunqi, Zhang, Weijian, Lang, Stanley, Yao, Nanhua, Hamatake, Robert, Hong, Zhi

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Structure-Based Library Design in Efficient Discovery of Novel Inhibitors von Yan, Shunqi, Selliah, Robert

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Structure–activity relationship (SAR) studies of quinoxalines as novel HCV NS5B RNA-dependent RNA polymerase inhibitors von Rong, Frank, Chow, Suetying, Yan, Shunqi, Larson, Gary, Hong, Zhi, Wu, Jim

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Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2‑HG in Vivo von Popovici-Muller, Janeta, Saunders, Jeffrey O, Salituro, Francesco G, Travins, Jeremy M, Yan, Shunqi, Zhao, Fang, Gross, Stefan, Dang, Lenny, Yen, Katharine E, Yang, Hua, Straley, Kimberly S, Jin, Shengfang, Kunii, Kaiko, Fantin, Valeria R, Zhang, Shunan, Pan, Qiongqun, Shi, Derek, Biller, Scott A, Su, Shinsan M

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Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy von Kung, Charles, Hixon, Jeff, Choe, Sung, Marks, Kevin, Gross, Stefan, Murphy, Erin, DeLaBarre, Byron, Cianchetta, Giovanni, Sethumadhavan, Shalini, Wang, Xiling, Yan, Shunqi, Gao, Yi, Fang, Cheng, Wei, Wentao, Jiang, Fan, Wang, Shaohui, Qian, Kevin, Saunders, Jeff, Driggers, Ed, Woo, Hin Koon, Kunii, Kaiko, Murray, Stuart, Yang, Hua, Yen, Katharine, Liu, Wei, Cantley, Lewis C., Vander Heiden, Matthew G., Su, Shinsan M., Jin, Shengfang, Salituro, Francesco G., Dang, Lenny

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An Optimized Protein Kinase C Activating Diacylglycerol Combining High Binding Affinity (K i) with Reduced Lipophilicity (log P) von Nacro, Kassoum, Sigano, Dina M, Yan, Shunqi, Nicklaus, Marc C, Pearce, Larry L, Lewin, Nancy E, Garfield, Susan H, Blumberg, Peter M, Marquez, Victor E

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Novel thiazolones as HCV NS5B polymerase allosteric inhibitors: Further designs, SAR, and X-ray complex structure von Yan, Shunqi, Larson, Gary, Wu, Jim Z., Appleby, Todd, Ding, Yili, Hamatake, Robert, Hong, Zhi, Yao, Nanhua

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Identification of novel, selective and potent Chk2 inhibitors von Larson, Gary, Yan, Shunqi, Chen, Huanming, Rong, Frank, Hong, Zhi, Wu, Jim Zhen

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QUINAZOLINE COMPOUNDS FOR TREATMENT OF DISEASE von YAN, Shunqi, YEH, Litain

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QUINAZOLINE COMPOUNDS FOR TREATMENT OF DISEASE von YAN, Shunqi, YEH, Litain

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Structural Identification of Two Metabolites of Catechins and Their Kinetics in Human Urine and Blood after Tea Ingestion von Li, Chuan, Lee, Mao-Jung, Sheng, Shuqun, Meng, Xiaofeng, Prabhu, Saileta, Winnik, Bozena, Huang, Baoming, Chung, Jee Y, Yan, Shunqi, Ho, Chi-Tang, Yang, Chung S

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QUINAZOLINE COMPOUNDS FOR TREATMENT OF DISEASE von YAN, Shunqi, YEH, Litain

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