LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft mo... von Yan, S. Betty, Peek, Victoria L., Ajamie, Rose, Buchanan, Sean G., Graff, Jeremy R., Heidler, Steven A., Hui, Yu-Hua, Huss, Karen L., Konicek, Bruce W., Manro, Jason R., Shih, Chuan, Stewart, Julie A., Stewart, Trent R., Stout, Stephanie L., Uhlik, Mark T., Um, Suzane L., Wang, Yong, Wu, Wenjuan, Yan, Lei, Yang, Wei J., Zhong, Boyu, Walgren, Richard A.

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MET-targeting antibody (emibetuzumab) and kinase inhibitor (merestinib) as single agent or in combination in a cancer model bearing MET exon 14 skipping von Yan, S. Betty, Um, Suzane L., Peek, Victoria L., Stephens, Jennifer R., Zeng, Wei, Konicek, Bruce W., Liu, Ling, Manro, Jason R., Wacheck, Volker, Walgren, Richard A.

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Recombinant Human Activated Protein C for the Postexposure Treatment of Ebola Hemorrhagic Fever von Hensley, Lisa E., Stevens, Edward L., Yan, S. Betty, Geisbert, Joan B., Macias, William L., Larsen, Tom, Daddario-DiCaprio, Kathleen M., Cassell, Gail H., Jahrling, Peter B., Geisbert, Thomas W.

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Troponin-I as a prognosticator of mortality in severe sepsis patients von John, Jijo, MD, Woodward, D. Bradley, MD, Wang, Yanping, PhD, Yan, S. Betty, PhD, Fisher, Diana, MS, Kinasewitz, Gary T., MD, Heiselman, Darell, DO

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Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569] von Kinasewitz, Gary T, Yan, S Betty, Basson, Bruce, Comp, Philip, Russell, James A, Cariou, Alain, Um, Suzane L, Utterback, Barbara, Laterre, Pierre-Francois, Dhainaut, Jean-François

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Low Levels of Protein C Are Associated With Poor Outcome in Severe Sepsis von Yan, S. Betty, Helterbrand, Jeffrey D., Hartman, Daniel L., Wright, Theressa J., Bernard, Gordon R.

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Safety and dose relationship of recombinant human activated protein C for coagulopathy in severe sepsis von Bernard, Gordon R, Ely, E Wesley, Wright, Theressa J, Fraiz, Joseph, Stasek, Jerome E, Russell, James A, Mayers, Irvin, Rosenfeld, Brian A, Morris, Peter E, Yan, S Betty, Helterbrand, Jeffery D

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Prognostic value of protein C concentrations in neutropenic patients at high risk of severe septic complications von Mesters, Rolf M, Helterbrand, Jeff, Utterback, Barbara G, Yan, S Betty, Chao, Y Bernice, Fernandez, Jose A, Griffin, John H, Hartman, Daniel L

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Drotrecogin alfa (activated) (recombinant human activated protein C) reduces host coagulopathy response in patients with severe sepsis von Dhainaut, Jean-François, Yan, S. Betty, Margolis, Benjamin D., Lorente, José A., Russell, James A., Freebairn, Ross C., Spapen, Herbert D., Riess, Hanno, Basson, Bruce, Johnson III, Gerald, Kinasewitz, Gary T.

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New insights into the protein C pathway: potential implications for the biological activities of drotrecogin alfa (activated) von Macias, William L, Yan, S Betty, Williams, Mark D, Um, Suzane L, Sandusky, George E, Ballard, Darryl W, Planquois, Jean-Michel S

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LY2875358, a neutralizing and internalizing anti-MET bivalent antibody, inhibits HGF-dependent and HGF-independent MET activation and tumor growth von Liu, Ling, Zeng, Wei, Wortinger, Mark A, Yan, S Betty, Cornwell, Paul, Peek, Victoria L, Stephens, Jennifer R, Tetreault, Jonathan W, Xia, Jinqi, Manro, Jason R, Credille, Kelly M, Ballard, Darryl W, Brown-Augsburger, Patricia, Wacheck, Volker, Chow, Chi-Kin, Huang, Lihua, Wang, Yong, Denning, Irene, Davies, Julian, Tang, Ying, Vaillancourt, Peter, Lu, Jirong

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Inhibition of Tumor Growth and Metastasis in Non―Small Cell Lung Cancer by LY2801653, an Inhibitor of Several Oncokinases, Including MET von WENJUAN WU, CHEN BI, CREDILLE, Kelly M, MANRO, Jason R, PEEK, Victoria L, DONOHO, Gregory P, LEI YAN, WIJSMAN, John A, YAN, S. Betty, WALGREN, Richard A

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Drotrecogin alfa (activated) in patients with severe sepsis presenting with purpura fulminans, meningitis, or meningococcal disease: a retrospective analysis of patients enrolled i... von Vincent, Jean-Louis, Nadel, Simon, Kutsogiannis, Demetrios J, Gibney, R T Noel, Yan, S Betty, Wyss, Virginia L, Bailey, Joan E, Mitchell, Carol L, Sarwat, Samiha, Shinall, Stephen M, Janes, Jonathan M

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Effect of drotrecogin alfa (activated) on human endothelial cell permeability and Rho kinase signaling von Zeng, Wei, Matter, William F, Yan, S Betty, Um, Suzane L, Vlahos, Chris J, Liu, Ling

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Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell... von Salgia, Ravi, Weaver, R. Waide, McCleod, Michael, Stille, John R., Yan, S. Betty, Roberson, Stephanie, Polzer, John, Flynt, Amy, Raddad, Eyas, Peek, Victoria L., Wijayawardana, Sameera R., Um, Suzane L., Gross, Steve, Connelly, Mark C., Morano, Carrie, Repollet, Madeline, Sanders, Renouard, Baeten, Kurt, D’Haese, David, Spigel, David R.

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Effect of recombinant human activated protein C on the bactericidal activity of human monocytes and modulation of pro-inflammatory cytokines in the presence of antimicrobial agents von Baltch, Aldona L., Bopp, Lawrence H., Ritz, William J., Michelsen, Phyllis B., Yan, S. Betty, Um, Suzane, Smith, Raymond P.

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Coagulopathy after successful cardiopulmonary resuscitation following cardiac arrest : Implication of the protein C anticoagulant pathway von ADRIE, Christophe, MONCHI, Mehran, LAURENT, Ivan, UM, Suzan, YAN, S. Betty, THUONG, Marie, CARIOU, Alain, CHARPENTIER, Julien, DHAINAUT, Jean Francois

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Soluble thrombomodulin, plasma-derived unactivated protein C, and recombinant human activated protein C in sepsis von Dhainaut, Jean-François, Yan, S Betty, Cariou, Alain, Mira, Jean-Paul

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Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia von Kerlin, Bryce A., Yan, S. Betty, Isermann, Berend H., Brandt, John T., Sood, Rashmi, Basson, Bruce R., Joyce, David E., Weiler, Hartmut, Dhainaut, Jean-Francois

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Effect of factor V Leiden polymorphism in severe sepsis and on treatment with recombinant human activated protein C von Yan, S Betty, Nelson, David R

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