LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation von Simon, Matthew, Van Meter, Michael, Ablaeva, Julia, Ke, Zhonghe, Gonzalez, Raul S., Taguchi, Taketo, De Cecco, Marco, Leonova, Katerina I., Kogan, Valeria, Helfand, Stephen L., Neretti, Nicola, Roichman, Asael, Cohen, Haim Y., Meer, Margarita V., Gladyshev, Vadim N., Antoch, Marina P., Gudkov, Andrei V., Sedivy, John M., Seluanov, Andrei, Gorbunova, Vera

Volltext

Telomeres and Longevity: A Cause or an Effect? von Adwan Shekhidem, Huda, Sharvit, Lital, Leman, Eva, Manov, Irena, Roichman, Asael, Holtze, Susanne, M Huffman, Derek, Y Cohen, Haim, Bernd Hildebrandt, Thomas, Shams, Imad, Atzmon, Gil

Volltext

Multiple Regulatory Layers of SREBP1/2 by SIRT6 von Elhanati, Sivan, Kanfi, Yariv, Varvak, Alexander, Roichman, Asael, Carmel-Gross, Ilana, Barth, Shaul, Gibor, Gilad, Cohen, Haim Y.

Volltext

SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα von Naiman, Shoshana, Huynh, Frank K., Gil, Reuven, Glick, Yair, Shahar, Yael, Touitou, Noga, Nahum, Liat, Avivi, Matan Y., Roichman, Asael, Kanfi, Yariv, Gertler, Asaf A., Doniger, Tirza, Ilkayeva, Olga R., Abramovich, Ifat, Yaron, Orly, Lerrer, Batia, Gottlieb, Eyal, Harris, Robert A., Gerber, Doron, Hirschey, Matthew D., Cohen, Haim Y.

Volltext

SIRT6 protects against pathological damage caused by diet‐induced obesity von Kanfi, Yariv, Peshti, Victoria, Gil, Reuven, Naiman, Shoshana, Nahum, Liat, Levin, Eran, Kronfeld‐Schor, Noga, Cohen, Haim Y.

Volltext

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase von Cohen, H.Y, Miller, C, Bitterman, K.J, Wall, N.R, Hekking, B, Kessler, B, Howitz, K.T, Gorospe, M, de Cabo, R, Sinclair, D.A

Volltext

The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance von Chuprin, Anna, Avin, Ayelet, Goldfarb, Yael, Herzig, Yonatan, Levi, Ben, Jacob, Adi, Sela, Asaf, Katz, Shir, Grossman, Moran, Guyon, Clotilde, Rathaus, Moran, Cohen, Haim Y, Sagi, Irit, Giraud, Matthieu, McBurney, Michael W, Husebye, Eystein S, Abramson, Jakub

Volltext

Dynamic regulation of N6,2′-O-dimethyladenosine (m6Am) in obesity von Ben-Haim, Moshe Shay, Pinto, Yishay, Moshitch-Moshkovitz, Sharon, Hershkovitz, Vera, Kol, Nitzan, Diamant-Levi, Tammy, Beeri, Michal Schnaider, Amariglio, Ninette, Cohen, Haim Y., Rechavi, Gideon

Volltext

Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1 von Bitterman, Kevin J, Anderson, Rozalyn M, Cohen, Haim Y, Latorre-Esteves, Magda, Sinclair, David A

Volltext

Regulation of the proapoptotic factor Bax by Ku70-dependent deubiquitylation von Amsel, Avigail D, Rathaus, Moran, Kronman, Noam, Cohen, Haim Y

Volltext

Directed evolution of SIRT6 for improved deacylation and glucose homeostasis maintenance von Gertman, Or, Omer, Dotan, Hendler, Adi, Stein, Daniel, Onn, Lior, Khukhin, Yana, Portillo, Miguel, Zarivach, Raz, Cohen, Haim Y., Toiber, Debra, Aharoni, Amir

Volltext

The complex role of SIRT6 in carcinogenesis von Lerrer, Batia, Gertler, Asaf A, Cohen, Haim Y

Volltext

New Role for Interleukin-13 Receptor α1 in Myocardial Homeostasis and Heart Failure von Amit, Uri, Kain, David, Wagner, Allon, Sahu, Avinash, Nevo-Caspi, Yael, Gonen, Nir, Molotski, Natali, Konfino, Tal, Landa, Natalie, Naftali-Shani, Nili, Blum, Galia, Merquiol, Emmanuelle, Karo-Atar, Danielle, Kanfi, Yariv, Paret, Gidi, Munitz, Ariel, Cohen, Haim Y, Ruppin, Eytan, Hannenhalli, Sridhar, Leor, Jonathan

Volltext

The yeast forkhead HCM1 controls life span independent of calorie restriction von Maoz, Noam, Gabay, Orshay, Waldman Ben-Asher, Hiba, Cohen, Haim Y

Volltext

Dietary Restriction: Standing Up for Sirtuins [With Response] von BAUR, JOEPH A., CHEN, DANICA, CHINI, EDUARDO N., CHUA, KATRIN, COHEN, HAIM Y., DE CABO, RAFAEL, DENG, CHUXIA, DIMMELER, STEFANIE, GIUS, DAVID, GUARENTE, LEONARD P., HELFAND, STEPHEN L., IMAI, SHIN-ICHIRO, ITOH, HIROSHI, KADOWAKI, TAKASHI, KOYA, DAISUKE, LEEUWENBURGH, CHRISTIAAN, MCBURNEY, MICHAEL, NABESHIMA, YO-ICHI, NERI, CHRISTIAN, OBERDOERFFER, PHILIPP, PESTELL, RICHARD G., ROGINA, BLANKA, SADOSHIMA, JUNICHI, SARTORELLI, VITTORIO, SERRANO, MANUEL, SINCLAIR, DAVID A., STEEGBORN, CLEMENS, TATAR, MARC, TISSENBAUM, HEIDI A., TONG, QIANG, TSUBOTA, KAZUO, VAQUERO, ALEJANDRO, VERDIN, ERIC, FONTANA, LUIGI, PARTRIDGE, LINDA, LONGO, VALTER D.

Volltext

DeubiKuitylation: A novel DUB enzymatic activity for the DNA repair protein, Ku70 von Rathaus, Moran, Lerrer, Batya, Cohen, Haim Y.

Volltext

SIRT6 exhibits nucleosome-dependent deacetylase activity von Gil, Reuven, Barth, Shaul, Kanfi, Yariv, Cohen, Haim Y

Volltext

SIRT6 Overexpression Improves Various Aspects of Mouse Healthspan von Roichman, Asael, Kanfi, Yariv, Glazz, Renana, Naiman, Shoshana, Amit, Uri, Landa, Natalie, Tinman, Simon, Stein, Ilan, Pikarsky, Eli, Leor, Jonathan, Cohen, Haim Y

Volltext

Nicotinamide, a SIRT1 inhibitor, inhibits differentiation and facilitates expansion of hematopoietic progenitor cells with enhanced bone marrow homing and engraftment von Peled, Tony, Shoham, Hadas, Aschengrau, Dorit, Yackoubov, Dima, Frei, Gabi, Rosenheimer G, Noga, Lerrer, Batya, Cohen, Haim Y, Nagler, Arnon, Fibach, Eitan, Peled, Amnon

Volltext

Breaking the Ceiling of Human Maximal Life span von Ben-Haim, Moshe Shay, Kanfi, Yariv, Mitchell, Sarah J, Maoz, Noam, Vaughan, Kelli L, Amariglio, Ninette, Lerrer, Batia, de Cabo, Rafael, Rechavi, Gideon, Cohen, Haim Y

Volltext