Medicinal Chemistry Strategies for the Modification of Bioactive Natural Products von Ding, Yuyang, Xue, Xiaoqian

Volltext

An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants von Cao, Minjie, Liu, Xue, Zhang, Yan, Xue, Xiaoqian, Zhou, X Edward, Melcher, Karsten, Gao, Pan, Wang, Fuxing, Zeng, Liang, Zhao, Yang, Zhao, Yang, Deng, Pan, Zhong, Dafang, Zhu, Jian-Kang, Xu, H Eric, Xu, Yong

Volltext

3D lithiophilic framework fixed on the surface of LLZTO solid electrolyte shaping the contact between Li metal and ceramic von Shi, Yuhao, Cai, Yifei, Zhao, Jiaqi, Wu, Tong, Xue, Xiaoqian, Lin, Tiesong, Lin, Panpan, Wang, Ce, Peng, He

Volltext

Discovery of Benzo[cd]indol-2(1H)‑ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation von Xue, Xiaoqian, Zhang, Yan, Liu, Zhaoxuan, Song, Ming, Xing, Yanli, Xiang, Qiuping, Wang, Zhen, Tu, Zhengchao, Zhou, Yulai, Ding, Ke, Xu, Yong

Volltext

Structure-Based Discovery and Optimization of Benzo[d]­isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer... von Zhang, Maofeng, Zhang, Yan, Song, Ming, Xue, Xiaoqian, Wang, Junjian, Wang, Chao, Zhang, Cheng, Li, Chenchang, Xiang, Qiuping, Zou, Lingjiao, Wu, Xishan, Wu, Chun, Dong, Baijun, Xue, Wei, Zhou, Yulai, Chen, Hongwu, Wu, Donghai, Ding, Ke, Xu, Yong

Volltext

Low temperature and rapid diffusion bonding of Ni3Al-based superalloy with Ni-based superalloy by spark plasma sintering von Wu, Tong, Wang, Ce, Yang, Jia, Xu, Rui, Xue, Xiaoqian, Fu, Mengchun, Zhao, Yuwei, Xu, Jiujie, Zhang, Qiuguang, Lin, Panpan, Yue, Xin, Lin, Tiesong, He, Peng

Volltext

ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer von Wang, Junjian, Zou, June X, Xue, Xiaoqian, Cai, Demin, Zhang, Yan, Duan, Zhijian, Xiang, Qiuping, Yang, Joy C, Louie, Maggie C, Borowsky, Alexander D, Gao, Allen C, Evans, Christopher P, Lam, Kit S, Xu, Jianzhen, Kung, Hsing-Jien, Evans, Ronald M, Xu, Yong, Chen, Hong-Wu

Volltext

Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer von Zhang, Yan, Wu, Xishan, Xue, Xiaoqian, Li, Chenchang, Wang, Junjian, Wang, Rui, Zhang, Cheng, Wang, Chao, Shi, Yudan, Zou, Lingjiao, Li, Qiu, Huang, Zenghong, Hao, Xiaojuan, Loomes, Kerry, Wu, Donghai, Chen, Hong-Wu, Xu, Jinxin, Xu, Yong

Volltext

Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer von Xiang, Qiuping, Wang, Chao, Zhang, Yan, Xue, Xiaoqian, Song, Ming, Zhang, Cheng, Li, Chenchang, Wu, Chun, Li, Kuai, Hui, Xiaoyan, Zhou, Yulai, Smaill, Jeff B., Patterson, Adam V., Wu, Donghai, Ding, Ke, Xu, Yong

Volltext

Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer von Xue, Xiaoqian, Zhang, Yan, Wang, Chao, Zhang, Maofeng, Xiang, Qiuping, Wang, Junjian, Wang, Anhui, Li, Chenchang, Zhang, Cheng, Zou, Lingjiao, Wang, Rui, Wu, Shuang, Lu, Yongzhi, Chen, Hongwu, Ding, Ke, Li, Guohui, Xu, Yong

Volltext

Discovery of 2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide derivatives as new RORγ inhibitors using virtual screening, synthesis and biological evaluation von Zhang, Yan, Xue, Xiaoqian, Jin, Xiangyu, Song, Yu, Li, Jing, Luo, Xiaoyu, Song, Ming, Yan, Weiqun, Song, Hongrui, Xu, Yong

Volltext

Discovery and optimization of novel N-benzyl-3,6-dimethylbenzo[d]isoxazol-5-amine derivatives as potent and selective TRIM24 bromodomain inhibitors with potential anti-cancer activ... von Hu, Qingqing, Wang, Chao, Xiang, Qiuping, Wang, Rui, Zhang, Cheng, Zhang, Maofeng, Xue, Xiaoqian, Luo, Guolong, Liu, Xiaomin, Wu, Xishan, Zhang, Yan, Wu, Donghai, Xu, Yong

Volltext

Rational design, synthesis and biological evaluation of ubiquinone derivatives as IDO1 inhibitors von Ding, Yuyang, Tang, Fei, Xue, Xiaoqian, Luo, Jinfeng, Hussain, Muzammal, Huang, Yanhui, Wang, Zhen, Jiang, Hao, Tu, Zhengchao, Zhang, Jiancun

Volltext

Correction: Corrigendum: ROR-[gamma] drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer von Wang, Junjian, Zou, June X, Xue, Xiaoqian, Cai, Demin, Zhang, Yan, Duan, Zhijian, Xiang, Qiuping

Volltext

Identification of N-phenyl-2-(N-phenylphenylsulfonamido)acetamides as new RORγ inverse agonists: Virtual screening, structure-based optimization, and biological evaluation von Song, Yu, Xue, Xiaoqian, Wu, Xishan, Wang, Rui, Xing, Yanli, Yan, Weiqun, Zhou, Yulai, Qian, Chao-Nan, Zhang, Yan, Xu, Yong

Volltext

Y08060: A Selective BET Inhibitor for Treatment of Prostate Cancer von Xiang, Qiuping, Zhang, Yan, Li, Jiaguo, Xue, Xiaoqian, Wang, Chao, Song, Ming, Zhang, Cheng, Wang, Rui, Li, Chenchang, Wu, Chun, Zhou, Yulai, Yang, Xiaohong, Li, Guohui, Ding, Ke, Xu, Yong

Volltext

Correction: Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer von Wang, Junjian, Zou, June X, Xue, Xiaoqian, Cai, Demin, Zhang, Yan, Duan, Zhijian, Xiang, Qiuping, Yang, Joy C, Louie, Maggie C, Borowsky, Alexander D, Gao, Allen C, Evans, Christopher P, Lam, Kit S, Xu, Jianzhen, Kung, Hsing-Jien, Evans, Ronald M, Xu, Yong, Chen, Hong-Wu

Volltext

Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer von Wang, Junjian, Zou, June X, Xue, Xiaoqian, Cai, Demin, Zhang, Yan, Duan, Zhijian, Xiang, Qiuping, Yang, Joy C, Louie, Maggie C, Borowsky, Alexander D, Gao, Allen C, Evans, Christopher P, Lam, Kit S, Xu, Jianzhen, Kung, Hsing-Jien, Evans, Ronald M, Xu, Yong, Chen, Hong-Wu

Volltext

Corrigendum: ROR-[gamma] drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer von Wang, Junjian, Zou, June X, Xue, Xiaoqian, Cai, Demin, Zhang, Yan, Duan, Zhijian, Xiang, Qiuping, Yang, Joy C, Louie, Maggie C, Borowsky, Alexander D, Gao, Allen C, Evans, Christopher P, Lam, Kit S, Xu, Jianzhen, Kung, Hsing-jien, Evans, Ronald M, Xu, Yong, Chen, Hong-wu

Volltext

ROR-[gamma] drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer von Wang, Junjian, Zou, June X, Xue, Xiaoqian, Cai, Demin, Zhang, Yan, Duan, Zhijian, Xiang, Qiuping

Volltext