Rapid non-uniform adaptation to conformation-specific KRAS(G12C) inhibition von Xue, Jenny Y., Zhao, Yulei, Aronowitz, Jordan, Mai, Trang T., Vides, Alberto, Qeriqi, Besnik, Kim, Dongsung, Li, Chuanchuan, de Stanchina, Elisa, Mazutis, Linas, Risso, Davide, Lito, Piro

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The G protein signaling regulator RGS3 enhances the GTPase activity of KRAS von Li, Chuanchuan, Vides, Alberto, Kim, Dongsung, Xue, Jenny Y, Zhao, Yulei, Lito, Piro

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Pan-KRAS inhibitor disables oncogenic signalling and tumour growth von Kim, Dongsung, Herdeis, Lorenz, Rudolph, Dorothea, Zhao, Yulei, Böttcher, Jark, Vides, Alberto, Ayala-Santos, Carlos I., Pourfarjam, Yasin, Cuevas-Navarro, Antonio, Xue, Jenny Y., Mantoulidis, Andreas, Bröker, Joachim, Wunberg, Tobias, Schaaf, Otmar, Popow, Johannes, Wolkerstorfer, Bernhard, Kropatsch, Katrin Gabriele, Qu, Rui, de Stanchina, Elisa, Sang, Ben, Li, Chuanchuan, McConnell, Darryl B., Kraut, Norbert, Lito, Piro

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Suppressing Nucleotide Exchange to Inhibit KRAS-Mutant Tumors von Zhao, Yulei, Xue, Jenny Y, Lito, Piro

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Quest for Clinically Effective RAF Dimer Inhibitors von Xue, Jenny Y, Lito, Piro

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Diverse alterations associated with resistance to KRAS(G12C) inhibition von Zhao, Yulei, Murciano-Goroff, Yonina R., Xue, Jenny Y., Ang, Agnes, Lucas, Jessica, Mai, Trang T., Da Cruz Paula, Arnaud F., Saiki, Anne Y., Mohn, Deanna, Achanta, Pragathi, Sisk, Ann E., Arora, Kanika S., Roy, Rohan S., Kim, Dongsung, Li, Chuanchuan, Lim, Lee P., Li, Mark, Bahr, Amber, Loomis, Brian R., de Stanchina, Elisa, Reis-Filho, Jorge S., Weigelt, Britta, Berger, Michael, Riely, Gregory, Arbour, Kathryn C., Lipford, J. Russell, Li, Bob T., Lito, Piro

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A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy von Wojtaszek, Jessica L., Chatterjee, Nimrat, Najeeb, Javaria, Ramos, Azucena, Lee, Minhee, Bian, Ke, Xue, Jenny Y., Fenton, Benjamin A., Park, Hyeri, Li, Deyu, Hemann, Michael T., Hong, Jiyong, Walker, Graham C., Zhou, Pei

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Adaptive Resistance to Dual BRAF/MEK Inhibition in BRAF-Driven Tumors through Autocrine FGFR Pathway Activation von Wang, Victoria E, Xue, Jenny Y, Frederick, Dennie T, Cao, Yi, Lin, Eva, Wilson, Catherine, Urisman, Anatoly, Carbone, David P, Flaherty, Keith T, Bernards, Rene, Lito, Piro, Settleman, Jeff, McCormick, Frank

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In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma von Nokin, Marie-Julie, Darbo, Elodie, Richard, Elodie, San José, Sonia, de Hita, Sergio, Prouzet-Mauleon, Valérie, Turcq, Béatrice, Gerardelli, Laura, Crake, Rebekah, Velasco, Valérie, Koopmansch, Benjamin, Lambert, Frederic, Xue, Jenny Y., Sang, Ben, Horne, Julie, Ziemons, Eric, Villanueva, Alberto, Blomme, Arnaud, Herfs, Michael, Cataldo, Didier, Calvayrac, Olivier, Porporato, Paolo, Nadal, Ernest, Lito, Piro, Jänne, Pasi A., Ricciuti, Biagio, Awad, Mark M., Ambrogio, Chiara, Santamaría, David

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In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAF V600E lung adenocarcinoma von Nokin, Marie-Julie, Darbo, Elodie, Richard, Elodie, San José, Sonia, de Hita, Sergio, Prouzet-Mauleon, Valérie, Turcq, Béatrice, Gerardelli, Laura, Crake, Rebekah, Velasco, Valérie, Koopmansch, Benjamin, Lambert, Frederic, Xue, Jenny Y, Sang, Ben, Horne, Julie, Ziemons, Eric, Villanueva, Alberto, Blomme, Arnaud, Herfs, Michael, Cataldo, Didier, Calvayrac, Olivier, Porporato, Paolo, Nadal, Ernest, Lito, Piro, Jänne, Pasi A, Ricciuti, Biagio, Awad, Mark M, Ambrogio, Chiara, Santamaría, David

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Abstract 622: Rapid non-uniform adaptation to conformation-specific KRAS G12Cinhibition von Xue, Jenny Y., Zhao, Yulei, Aronowitz, Jordan, Mai, Trang T., Vides, Alberto, Qeriqi, Besnik, Kim, Dongsung, Li, Chuanchuan, de Stanchina, Elisa, Mazutis, Linas, Risso, Davide, Lito, Piro

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Rapid non-uniform adaptation to conformation-specific KRASG12C inhibition von Xue, Jenny Y., Zhao, Yulei, Aronowitz, Jordan, Mai, Trang T., Vides, Alberto, Qeriqi, Besnik, Kim, Dongsung, Li, Chuanchuan, de Stanchina, Elisa, Mazutis, Linas, Risso, Davide, Lito, Piro

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A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy von Wojtaszek, Jessica L., Chatterjee, Nimrat, Najeeb, Javaria, Ramos, Azucena, Lee, Minhee, Bian, Ke, Xue, Jenny Y., Fenton, Benjamin A., Park, Hyeri, Li, Deyu, Hemann, Michael T., Hong, Jiyong, Walker, Graham C., Zhou, Pei

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In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma von Nokin, Marie-Julie, Darbo, Elodie, Richard, Elodie, San José, Sonia, de Hita, Sergio, Prouzet-Mauleon, Valérie, Turcq, Béatrice, Gerardelli, Laura, Crake, Rebekah, Velasco, Valérie, Koopmansch, Benjamin, Lambert, Frederic, Xue, Jenny Y, Sang, Ben, Horne, Julie, Ziemons, Eric, Villanueva, Alberto, Blomme, Arnaud, Herfs, Michael, Cataldo, Didier, Calvayrac, Olivier, Porporato, Paolo, Nadal, Ernest, Lito, Piro, Jänne, Pasi A, Ricciuti, Biagio, Awad, Mark M, Ambrogio, Chiara, Santamaría, David

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Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1–2 trial von Locke, Frederick L, Ghobadi, Armin, Jacobson, Caron A, Miklos, David B, Lekakis, Lazaros J, Oluwole, Olalekan O, Lin, Yi, Braunschweig, Ira, Hill, Brian T, Timmerman, John M, Deol, Abhinav, Reagan, Patrick M, Stiff, Patrick, Flinn, Ian W, Farooq, Umar, Goy, Andre, McSweeney, Peter A, Munoz, Javier, Siddiqi, Tanya, Chavez, Julio C, Herrera, Alex F, Bartlett, Nancy L, Wiezorek, Jeffrey S, Navale, Lynn, Xue, Allen, Jiang, Yizhou, Bot, Adrian, Rossi, John M, Kim, Jenny J, Go, William Y, Neelapu, Sattva S

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Early detection and staging of chronic liver diseases with a protein MRI contrast agent von Salarian, Mani, Turaga, Ravi Chakra, Xue, Shenghui, Nezafati, Maysam, Hekmatyar, Khan, Qiao, Jingjuan, Zhang, Yinwei, Tan, Shanshan, Ibhagui, Oluwatosin Y., Hai, Yan, Li, Jibiao, Mukkavilli, Rao, Sharma, Malvika, Mittal, Pardeep, Min, Xiaoyi, Keilholz, Shella, Yu, Liqing, Qin, Gengshen, Farris, Alton Brad, Liu, Zhi-Ren, Yang, Jenny J.

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Resistance Mechanisms for the Bruton's Tyrosine Kinase Inhibitor Ibrutinib von Woyach, Jennifer A, Furman, Richard R, Liu, Ta-Ming, Ozer, Hatice Gulcin, Zapatka, Marc, Ruppert, Amy S, Xue, Ling, Li, Daniel Hsieh-Hsin, Steggerda, Susanne M, Versele, Matthias, Dave, Sandeep S, Zhang, Jenny, Yilmaz, Ayse Selen, Jaglowski, Samantha M, Blum, Kristie A, Lozanski, Arletta, Lozanski, Gerard, James, Danelle F, Barrientos, Jacqueline C, Lichter, Peter, Stilgenbauer, Stephan, Buggy, Joseph J, Chang, Betty Y, Johnson, Amy J, Byrd, John C

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Cisplatin-Mediated Upregulation of APE2 Binding to MYH9 Provokes Mitochondrial Fragmentation and Acute Kidney Injury von Hu, Yi, Yang, Chun, Amorim, Tania, Maqbool, Mohsin, Lin, Jenny, Li, Chen, Fang, Chuanfeng, Xue, Li, Kwart, Ariel, Fang, Hua, Yin, Mei, Janocha, Allison J, Tsuchimoto, Daisuke, Nakabeppu, Yusaku, Jiang, Xiaofeng, Mejia-Garcia, Alex, Anwer, Faiz, Khouri, Jack, Qi, Xin, Zheng, Qing Y, Yu, Jennifer S, Yan, Shan, LaFramboise, Thomas, Anderson, Kenneth C, Herlitz, Leal C, Munshi, Nikhil C, Lin, Jianhong, Zhao, Jianjun

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A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection von Tang, Xuming, Xue, Dongxiang, Zhang, Tuo, Nilsson-Payant, Benjamin E., Carrau, Lucia, Duan, Xiaohua, Gordillo, Miriam, Tan, Adrian Y., Qiu, Yunping, Xiang, Jenny, Schwartz, Robert E., tenOever, Benjamin R., Evans, Todd, Chen, Shuibing

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Designing Calcium-Binding Proteins for Molecular MR Imaging von Salarian, Mani, Xue, Shenghui, Ibhagui, Oluwatosin Y., Yang, Jenny J.

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