Quest for Clinically Effective RAF Dimer Inhibitors von Xue, Jenny Y, Lito, Piro

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Suppressing Nucleotide Exchange to Inhibit KRAS-Mutant Tumors von Zhao, Yulei, Xue, Jenny Y, Lito, Piro

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Rapid non-uniform adaptation to conformation-specific KRAS(G12C) inhibition von Xue, Jenny Y., Zhao, Yulei, Aronowitz, Jordan, Mai, Trang T., Vides, Alberto, Qeriqi, Besnik, Kim, Dongsung, Li, Chuanchuan, de Stanchina, Elisa, Mazutis, Linas, Risso, Davide, Lito, Piro

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The G protein signaling regulator RGS3 enhances the GTPase activity of KRAS von Li, Chuanchuan, Vides, Alberto, Kim, Dongsung, Xue, Jenny Y, Zhao, Yulei, Lito, Piro

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Pan-KRAS inhibitor disables oncogenic signalling and tumour growth von Kim, Dongsung, Herdeis, Lorenz, Rudolph, Dorothea, Zhao, Yulei, Böttcher, Jark, Vides, Alberto, Ayala-Santos, Carlos I., Pourfarjam, Yasin, Cuevas-Navarro, Antonio, Xue, Jenny Y., Mantoulidis, Andreas, Bröker, Joachim, Wunberg, Tobias, Schaaf, Otmar, Popow, Johannes, Wolkerstorfer, Bernhard, Kropatsch, Katrin Gabriele, Qu, Rui, de Stanchina, Elisa, Sang, Ben, Li, Chuanchuan, McConnell, Darryl B., Kraut, Norbert, Lito, Piro

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Diverse alterations associated with resistance to KRAS(G12C) inhibition von Zhao, Yulei, Murciano-Goroff, Yonina R., Xue, Jenny Y., Ang, Agnes, Lucas, Jessica, Mai, Trang T., Da Cruz Paula, Arnaud F., Saiki, Anne Y., Mohn, Deanna, Achanta, Pragathi, Sisk, Ann E., Arora, Kanika S., Roy, Rohan S., Kim, Dongsung, Li, Chuanchuan, Lim, Lee P., Li, Mark, Bahr, Amber, Loomis, Brian R., de Stanchina, Elisa, Reis-Filho, Jorge S., Weigelt, Britta, Berger, Michael, Riely, Gregory, Arbour, Kathryn C., Lipford, J. Russell, Li, Bob T., Lito, Piro

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A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy von Wojtaszek, Jessica L., Chatterjee, Nimrat, Najeeb, Javaria, Ramos, Azucena, Lee, Minhee, Bian, Ke, Xue, Jenny Y., Fenton, Benjamin A., Park, Hyeri, Li, Deyu, Hemann, Michael T., Hong, Jiyong, Walker, Graham C., Zhou, Pei

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Adaptive Resistance to Dual BRAF/MEK Inhibition in BRAF-Driven Tumors through Autocrine FGFR Pathway Activation von Wang, Victoria E, Xue, Jenny Y, Frederick, Dennie T, Cao, Yi, Lin, Eva, Wilson, Catherine, Urisman, Anatoly, Carbone, David P, Flaherty, Keith T, Bernards, Rene, Lito, Piro, Settleman, Jeff, McCormick, Frank

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In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma von Nokin, Marie-Julie, Darbo, Elodie, Richard, Elodie, San José, Sonia, de Hita, Sergio, Prouzet-Mauleon, Valérie, Turcq, Béatrice, Gerardelli, Laura, Crake, Rebekah, Velasco, Valérie, Koopmansch, Benjamin, Lambert, Frederic, Xue, Jenny Y., Sang, Ben, Horne, Julie, Ziemons, Eric, Villanueva, Alberto, Blomme, Arnaud, Herfs, Michael, Cataldo, Didier, Calvayrac, Olivier, Porporato, Paolo, Nadal, Ernest, Lito, Piro, Jänne, Pasi A., Ricciuti, Biagio, Awad, Mark M., Ambrogio, Chiara, Santamaría, David

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In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAF V600E lung adenocarcinoma von Nokin, Marie-Julie, Darbo, Elodie, Richard, Elodie, San José, Sonia, de Hita, Sergio, Prouzet-Mauleon, Valérie, Turcq, Béatrice, Gerardelli, Laura, Crake, Rebekah, Velasco, Valérie, Koopmansch, Benjamin, Lambert, Frederic, Xue, Jenny Y, Sang, Ben, Horne, Julie, Ziemons, Eric, Villanueva, Alberto, Blomme, Arnaud, Herfs, Michael, Cataldo, Didier, Calvayrac, Olivier, Porporato, Paolo, Nadal, Ernest, Lito, Piro, Jänne, Pasi A, Ricciuti, Biagio, Awad, Mark M, Ambrogio, Chiara, Santamaría, David

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Abstract 622: Rapid non-uniform adaptation to conformation-specific KRAS G12Cinhibition von Xue, Jenny Y., Zhao, Yulei, Aronowitz, Jordan, Mai, Trang T., Vides, Alberto, Qeriqi, Besnik, Kim, Dongsung, Li, Chuanchuan, de Stanchina, Elisa, Mazutis, Linas, Risso, Davide, Lito, Piro

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Rapid non-uniform adaptation to conformation-specific KRASG12C inhibition von Xue, Jenny Y., Zhao, Yulei, Aronowitz, Jordan, Mai, Trang T., Vides, Alberto, Qeriqi, Besnik, Kim, Dongsung, Li, Chuanchuan, de Stanchina, Elisa, Mazutis, Linas, Risso, Davide, Lito, Piro

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A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy von Wojtaszek, Jessica L., Chatterjee, Nimrat, Najeeb, Javaria, Ramos, Azucena, Lee, Minhee, Bian, Ke, Xue, Jenny Y., Fenton, Benjamin A., Park, Hyeri, Li, Deyu, Hemann, Michael T., Hong, Jiyong, Walker, Graham C., Zhou, Pei

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In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma von Nokin, Marie-Julie, Darbo, Elodie, Richard, Elodie, San José, Sonia, de Hita, Sergio, Prouzet-Mauleon, Valérie, Turcq, Béatrice, Gerardelli, Laura, Crake, Rebekah, Velasco, Valérie, Koopmansch, Benjamin, Lambert, Frederic, Xue, Jenny Y, Sang, Ben, Horne, Julie, Ziemons, Eric, Villanueva, Alberto, Blomme, Arnaud, Herfs, Michael, Cataldo, Didier, Calvayrac, Olivier, Porporato, Paolo, Nadal, Ernest, Lito, Piro, Jänne, Pasi A, Ricciuti, Biagio, Awad, Mark M, Ambrogio, Chiara, Santamaría, David

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Designing Calcium-Binding Proteins for Molecular MR Imaging von Salarian, Mani, Xue, Shenghui, Ibhagui, Oluwatosin Y., Yang, Jenny J.

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Cough mixture abuse and rhabdomyolysis von Tsang, Jenny S K, Au, W Y

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Simple biologically informed inflammatory index of two serum cytokines predicts 10 year all-cause mortality in older adults von Varadhan, Ravi, Yao, Wenliang, Matteini, Amy, Beamer, Brock A, Xue, Qian-Li, Yang, Huanle, Manwani, Bhavish, Reiner, Alexander, Jenny, Nancy, Parekh, Neel, Fallin, M Daniele, Newman, Anne, Bandeen-Roche, Karen, Tracy, Russell, Ferrucci, Luigi, Walston, Jeremy

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Myocardial brain-derived neurotrophic factor regulates cardiac bioenergetics through the transcription factor Yin Yang 1 von Yang, Xue, Zhang, Manling, Xie, Bingxian, Peng, Zishan, Manning, Janet R, Zimmerman, Raymond, Wang, Qin, Wei, An-Chi, Khalifa, Moustafa, Reynolds, Michael, Jin, Jenny, Om, Matthew, Zhu, Guangshuo, Bedja, Djahida, Jiang, Hong, Jurczak, Michael, Shiva, Sruti, Scott, Iain, O'Rourke, Brian, Kass, David A, Paolocci, Nazareno, Feng, Ning

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SARS-CoV-2 infection induces beta cell transdifferentiation von Tang, Xuming, Uhl, Skyler, Zhang, Tuo, Xue, Dongxiang, Li, Bo, Vandana, J. Jeya, Acklin, Joshua A., Bonnycastle, Lori L., Narisu, Narisu, Erdos, Michael R., Bram, Yaron, Chandar, Vasuretha, Chong, Angie Chi Nok, Lacko, Lauretta A., Min, Zaw, Lim, Jean K., Borczuk, Alain C., Xiang, Jenny, Naji, Ali, Collins, Francis S., Evans, Todd, Liu, Chengyang, tenOever, Benjamin R., Schwartz, Robert E., Chen, Shuibing

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Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumors of childhood and adolescence von Xu, Lin, Pierce, Joshua L., Sanchez, Angelica, Chen, Kenneth S., Shukla, Abhay A., Fustino, Nicholas J., Stuart, Sarai H., Bagrodia, Aditya, Xiao, Xue, Guo, Lei, Krailo, Mark D., Shaikh, Furqan, Billmire, Deborah F., Pashankar, Farzana, Bestrashniy, Jessica, Oosterhuis, J. Wolter, Gillis, Ad J. M., Xie, Yang, Teot, Lisa, Mora, Jaume, Poynter, Jenny N., Rakheja, Dinesh, Looijenga, Leendert H. J., Draper, Bruce W., Frazier, A. Lindsay, Amatruda, James F.

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