Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors von Zhao, Li-Hua, Yin, Yanting, Yang, Dehua, Liu, Bo, Hou, Li, Wang, Xiaoxi, Pal, Kuntal, Jiang, Yi, Feng, Yang, Cai, Xiaoqing, Dai, Antao, Liu, Mingyao, Wang, Ming-Wei, Melcher, Karsten, Xu, H.Eric

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Structural Basis for Parathyroid Hormone-related Protein Binding to the Parathyroid Hormone Receptor and Design of Conformation-selective Peptides von Pioszak, Augen A., Parker, Naomi R., Gardella, Thomas J., Xu, H.Eric

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A novel prostate cancer therapeutic strategy using icaritin-activated arylhydrocarbon-receptor to co-target androgen receptor and its splice variants von Sun, Feng, Indran, Inthrani R, Zhang, Zhi Wei, Tan, M H Eileen, Li, Yu, Lim, Z L Ryan, Hua, Rui, Yang, Chong, Soon, Fen-Fen, Li, Jun, Xu, H Eric, Cheung, Edwin, Yong, Eu-Leong

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Crystallographic Identification and Functional Characterization of Phospholipids as Ligands for the Orphan Nuclear Receptor Steroidogenic Factor-1 von Li, Yong, Choi, Mihwa, Cavey, Greg, Daugherty, Jennifer, Suino, Kelly, Kovach, Amanda, Bingham, Nathan C., Kliewer, Steven A., Xu, H.Eric

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Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition von Bledsoe, Randy K., Montana, Valerie G., Stanley, Thomas B., Delves, Chris J., Apolito, Christopher J., McKee, David D., Consler, Thomas G., Parks, Derek J., Stewart, Eugene L., Willson, Timothy M., Lambert, Millard H., Moore, John T., Pearce, Kenneth H., Xu, H.Eric

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Dimeric Arrangement of the Parathyroid Hormone Receptor and a Structural Mechanism for Ligand-induced Dissociation von Pioszak, Augen A., Harikumar, Kaleeckal G., Parker, Naomi R., Miller, Laurence J., Xu, H.Eric

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Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors von Xu, H.Eric, Lambert, Millard H, Montana, Valerie G, Parks, Derek J, Blanchard, Steven G, Brown, Peter J, Sternbach, Daniel D, Lehmann, Jürgen M, Wisely, G.Bruce, Willson, Timothy M, Kliewer, Steven A, Milburn, Michael V

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Gal80-Gal80 interaction on adjacent Gal4p binding sites is required for complete GAL gene repression von Melcher, Karsten, Xu, H. Eric

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Rhodium(III)-Catalyzed Regioselective Direct C-2 Alkenylation of Indoles Assisted by the Removable N-(2-Pyrimidyl) Group von Gong, Binwei, Shi, Jingjing, Wang, Xiaowei, Yan, Yunnan, Li, Qiu, Meng, Yanqiu, Xu, H. Eric, Yi, Wei

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Structural and Functional Study of d-Glucuronyl C5-epimerase von Qin, Yi, Ke, Jiyuan, Gu, Xin, Fang, Jianping, Wang, Wucheng, Cong, Qifei, Li, Jie, Tan, Jinzhi, Brunzelle, Joseph S., Zhang, Chenghai, Jiang, Yi, Melcher, Karsten, Li, Jin-ping, Xu, H.Eric, Ding, Kan

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Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor von Zhou, X. Edward, Suino-Powell, Kelly M., Li, Jun, He, Yuanzheng, MacKeigan, Jeffrey P., Melcher, Karsten, Yong, Eu-Leong, Xu, H. Eric

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A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα protein von CHI TZE TIONG, CHEN CHEN, YOUNG, Eu-Leong, SHI JUN ZHANG, JUN LI, SOSHILOV, Anatoly, DENISON, Michael S, LEE, Lawrence Soon-U, TAM, Vincent H, SHIH PENG WONG, XU, H. Eric

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The Nuclear Xenobiotic Receptor CAR: Structural Determinants of Constitutive Activation and Heterodimerization von Suino, Kelly, Peng, Li, Reynolds, Ross, Li, Yong, Cha, Ji-Young, Repa, Joyce J., Kliewer, Steven A., Xu, H.Eric

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Activation of Nuclear Receptors: A Perspective from Structural Genomics von Li, Yong, Lambert, Millard H, Xu, H.Eric

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Asymmetry in the PPARγ/RXRα Crystal Structure Reveals the Molecular Basis of Heterodimerization among Nuclear Receptors von Gampe, Robert T., Montana, Valerie G., Lambert, Millard H., Miller, Aaron B., Bledsoe, Randy K., Milburn, Michael V., Kliewer, Steven A., Willson, Timothy M., Xu, H.Eric

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Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ)—synthesis and biological activity von Sznaidman, Marcos L., Haffner, Curt D., Maloney, Patrick R., Fivush, Adam, Chao, Esther, Goreham, Donna, Sierra, Michael L., LeGrumelec, Christelle, Xu, H.Eric, Montana, Valerie G., Lambert, Millard H., Willson, Timothy M., Oliver, William R., Sternbach, Daniel D.

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The cryo-electron microscopy structure of γ-secretase: towards complex assembly, substrate recognition and a catalytic mechanism von Kang, Yanyong, Melcher, Karsten, Xu, H. Eric

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Bioluminescence Resonance Energy Transfer (BRET) Assay for Determination of Molecular Interactions in Living Cells von Harikumar, Kaleeckal G, Yan, Yan, Xu, Ting-Hai, Melcher, Karsten, Xu, H Eric, Miller, Laurence J

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Crystallographic Identification and Functional Characterization of Phospholipids as Ligands for the Orphan Nuclear Receptor Steroidogenic Factor-1 von Li, Yong, Choi, Mihwa, Cavey, Greg, Daugherty, Jennifer, Suino, Kelly, Kovach, Amanda, Bingham, Nathan C., Kliewer, Steven A., Xu, H.Eric

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Modulation of [beta]-Catenin Signaling by Glucagon Receptor Activation von Ke, Jiyuan, Zhang, Chenghai, Harikumar, Kaleeckal G, Zylstra-Diegel, Cassandra R, Wang, Liren, Mowry, Laura E, Miller, Laurence J, Williams, Bart O, Xu, H. Eric

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