The FBXW2–MSX2–SOX2 axis regulates stem cell property and drug resistance of cancer cells von Yin, Yuan, Xie, Chuan-Ming, Li, Hua, Tan, Mingjia, Chen, Guoan, Schiff, Rachel, Xiong, Xiufang, Sun, Yi

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The MTORC1-mediated autophagy is regulated by the FBXW7-SHOC2-RPTOR axis von Xie, Chuan-Ming, Sun, Yi

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Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation von Xie, Chuan-Ming, Chan, Wood Yee, Yu, Sidney, Zhao, Jun, Cheng, Christopher H.K.

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Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation von Lin, Xiao-Tong, Yu, Hong-Qiang, Fang, Lei, Tan, Ye, Liu, Ze-Yu, Wu, Di, Zhang, Jie, Xiong, Hao-Jun, Xie, Chuan-Ming

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Elevated FBXL6 expression in hepatocytes activates VRK2-transketolase-ROS-mTOR-mediated immune evasion and liver cancer metastasis in mice von Zhang, Jie, Lin, Xiao-Tong, Yu, Hong-Qiang, Fang, Lei, Wu, Di, Luo, Yuan-Deng, Zhang, Yu-Jun, Xie, Chuan-Ming

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Elevated expression of WSB2 degrades p53 and activates the IGFBP3-AKT-mTOR-dependent pathway to drive hepatocellular carcinoma von Li, Xun, Zhang, Cheng-Cheng, Lin, Xiao-Tong, Zhang, Jie, Zhang, Yu-Jun, Yu, Hong-Qiang, Liu, Ze-Yu, Gong, Yi, Zhang, Lei-Da, Xie, Chuan-Ming

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Targeting autophagy enhances heat stress-induced apoptosis via the ATP-AMPK-mTOR axis for hepatocellular carcinoma von Jiang, Jiayun, Chen, Shihan, Li, Kun, Zhang, Chang, Tan, Yunhua, Deng, Qingsong, Chai, Yuelong, Wang, Xiaofei, Chen, Geng, Feng, Kai, Zhang, Leida, Xie, Chuan-Ming, Ma, Kuansheng

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Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice von Lin, Xiao-Tong, Zhang, Jie, Liu, Ze-Yu, Wu, Di, Fang, Lei, Li, Chun-Ming, Yu, Hong-Qiang, Xie, Chuan-Ming

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The FBXW7-SHOC2-Raptor Axis Controls the Cross-Talks between the RAS-ERK and mTORC1 Signaling Pathways von Xie, Chuan-Ming, Tan, Mingjia, Lin, Xiao-Tong, Wu, Di, Jiang, Yihan, Tan, Ye, Li, Haomin, Ma, Yuanyuan, Xiong, Xiufang, Sun, Yi

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Silencing of EEF2K (eukaryotic elongation factor-2 kinase) reveals AMPK-ULK1-dependent autophagy in colon cancer cells von Xie, Chuan-Ming, Liu, Xiao-Yu, Sham, Kathy WY, Lai, Josie MY, Cheng, Christopher HK

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FBXO43 increases CCND1 stability to promote hepatocellular carcinoma cell proliferation and migration von Li, Chun-Ming, Zhang, Jie, Wu, Wu, Zhu, Zhu, Li, Feng, Wu, Di, Wang, Xiao-Jun, Xie, Chuan-Ming, Gong, Jian-Ping

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Mutant Kras and mTOR crosstalk drives hepatocellular carcinoma development via PEG3/STAT3/BEX2 signaling von Luo, Yuan-Deng, Liu, Xiao-Yu, Fang, Lei, Yu, Hong-Qiang, Zhang, Yu-Jun, Chen, Min, Zhang, Lei-Da, Xie, Chuan-Ming

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Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib von Yang, Zelong, Zhang, Jie, Lin, Xiaotong, Wu, Di, Li, Guixi, Zhong, Chunlian, Fang, Lei, Jiang, Peng, Yin, Liangyu, Zhang, Leida, Bie, Ping, Xie, Chuan-Ming

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In vivo analysis of FBXO45-mediated fibrosis and liver tumorigenesis in a chemically induced mouse model of hepatocellular carcinoma von Zhang, Jie, Lin, Xiao-Tong, Fang, Lei, Xie, Chuan-Ming

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An optimized protocol to detect protein ubiquitination and activation by ubiquitination assay in vivo and CCK-8 assay von Lin, Xiao-Tong, Zhang, Jie, Xie, Chuan-Ming

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Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK von Cheng, Zhe, Pang, Tao, Gu, Min, Gao, An-Hui, Xie, Chuan-Ming, Li, Jing-Ya, Nan, Fa-Jun, Li, Jia

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Elevated Sodium Pump α3 Subunit Expression Promotes Colorectal Liver Metastasis via the p53-PTEN/IGFBP3-AKT-mTOR Axis von Wu, Di, Yu, Hong-Qiang, Xiong, Hao-Jun, Zhang, Yu-Jun, Lin, Xiao-Tong, Zhang, Jie, Wu, Wu, Wang, Teng, Liu, Xiao-Yu, Xie, Chuan-Ming

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p53 haploinsufficiency and increased mTOR signalling define a subset of aggressive hepatocellular carcinoma von Luo, Yuan-Deng, Fang, Lei, Yu, Hong-Qiang, Zhang, Jie, Lin, Xiao-Tong, Liu, Xiao-Yu, Wu, Di, Li, Gui-Xi, Huang, Deng, Zhang, Yu-Jun, Chen, Shu, Jiang, Yan, Shuai, Ling, He, Yu, Zhang, Lei-Da, Bie, Ping, Xie, Chuan-Ming

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Prognostic and predicted significance of Ubqln2 in patients with hepatocellular carcinoma von Luo, Yuan‐Deng, Yu, Hong‐Qiang, Liu, Xiao‐Yu, Huang, Deng, Dai, Hai‐Su, Fang, Lei, Zhang, Yu‐Jun, Lai, Jie‐Juan, Jiang, Yan, Shuai, Ling, Zhang, Lei‐Da, Chen, Geng, Bie, Ping, Xie, Chuan‐Ming

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Understanding the effect of social media marketing activity for promoting intention to participate in martial arts von Xie, Ming-Chuan, Chang, Yao-Chuan, Cai, Chuan-Ming

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