A potential antibody repertoire diversification mechanism through tyrosine sulfation for biotherapeutics engineering and production von Zhong, Xiaotian, D'Antona, Aaron M

Volltext

Editorial: Mechanisms and strategies of unconventional antibody diversification for greater immune adaptability von Dimitrov, Jordan D., Mwangi, Waithaka, Zhong, Xiaotian

Volltext

Cysteine metabolic engineering and selective disulfide reduction produce superior antibody-drug-conjugates von Procopio-Melino, Renée, Kotch, Frank W., Prashad, Amar S., Gomes, Jose M., Wang, Wenge, Arve, Bo, Dawdy, Andrew, Chen, Lawrence, Sperry, Justin, Hosselet, Christine, He, Tao, Kriz, Ronald, Lin, Laura, Marquette, Kimberly, Tchistiakova, Lioudmila, Somers, Will, Rouse, Jason C., Zhong, Xiaotian

Volltext

Debate on the relationship between Helicobacter pylori infection and inflammatory bowel disease: a bibliometric analysis von Wang, Ziye, Zhao, Shiqing, Zhong, Xiaotian, Su, Yi, Song, Yahan, Li, Jun, Shi, Yanyan

Volltext

Effects and mechanisms of Helicobacter pylori on cancers development and immunotherapy von Zhong, Xiaotian, Zheng, Huiling, Zhao, Shiqing, Wang, Ziye, Su, Yi, Zhong, Kaili, Wang, Mopei, Shi, Yanyan

Volltext

Behind the development of technology: The transition of innovation modes in China’s wind turbine manufacturing industry von Ru, Peng, Zhi, Qiang, Zhang, Fang, Zhong, Xiaotian, Li, Jianqiang, Su, Jun

Volltext

Recent Advances in the Molecular Design and Applications of Multispecific Biotherapeutics von Zhong, Xiaotian, D'Antona, Aaron M

Volltext

Modeling and mitigation of high-concentration antibody viscosity through structure-based computer-aided protein design von Apgar, James R, Tam, Amy S P, Sorm, Rhady, Moesta, Sybille, King, Amy C, Yang, Han, Kelleher, Kerry, Murphy, Denise, D'Antona, Aaron M, Yan, Guoying, Zhong, Xiaotian, Rodriguez, Linette, Ma, Weijun, Ferguson, Darren E, Carven, Gregory J, Bennett, Eric M, Lin, Laura

Volltext

Transient CHO expression platform for robust antibody production and its enhanced N‐glycan sialylation on therapeutic glycoproteins von Zhong, Xiaotian, Ma, Weijun, Meade, Caryl L., Tam, Amy S., Llewellyn, Eliza, Cornell, Richard, Cote, Kaffa, Scarcelli, John J., Marshall, Jeffrey K., Tzvetkova, Boriana, Figueroa, Bruno, DiNino, Dana, Sievers, Annette, Lee, Christopher, Guo, Jane, Mahan, Evan, Francis, Christopher, Lam, Khetemenee, D'Antona, Aaron M., Zollner, Richard, Zhu, Hongli L., Kriz, Ron, Somers, Will, Lin, Laura

Volltext

New Opportunities in Glycan Engineering for Therapeutic Proteins von Zhong, Xiaotian, D'Antona, Aaron M, Scarcelli, John J, Rouse, Jason C

Volltext

Biological Insights into Therapeutic Protein Modifications throughout Trafficking and Their Biopharmaceutical Applications von Zhong, Xiaotian, Wright, Jill F.

Volltext

Metabolic Engineering of Glycofusion Bispecific Antibodies for α-Dystroglycanopathies von Zhong, Xiaotian, Yan, Guoying Grace, Chaturvedi, Apurva, Li, Xiuling, Gao, Yijie, Girgenrath, Mahasweta, Corcoran, Chris J, Diblasio-Smith, Liz, LaVallie, Edward R, de Rham, Teresse, Zhou, Jing, Abel, Molica, Riegel, Logan, Lim, Sean K H, Bloom, Laird, Lin, Laura, D'Antona, Aaron M

Volltext

Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5 von Mosyak, Lidia, Georgiadis, Katy, Shane, Tania, Svenson, Kristine, Hebert, Tracy, McDonagh, Thomas, Mackie, Stewart, Olland, Stephane, Lin, Laura, Zhong, Xiaotian, Kriz, Ronald, Reifenberg, Erica L., Collins‐Racie, Lisa A., Corcoran, Christopher, Freeman, Bethany, Zollner, Richard, Marvell, Tod, Vera, Matthew, Sum, Phaik‐Eng, Lavallie, Edward R., Stahl, Mark, Somers, William

Volltext

Exploring Parametric and Mechanistic Differences between Expi293FTM and ExpiCHO-STM Cells for Transient Antibody Production Optimization von Zhou, Jing, Yan, Guoying, Cluckey, David, Meade, Caryl, Ruth, Margaret, Sorm, Rhady, Tam, Amy, Lim, Sean, Petridis, Constantine, Lin, Laura, D’Antona, Aaron, Zhong, Xiaotian

Volltext

Phosphodiesterase 11A in brain is enriched in ventral hippocampus and deletion causes psychiatric disease-related phenotypes von Kelly, Michele P., Logue, Sheree F., Brennan, Julie, Day, Jonathon P., Lakkaraju, Subha, Jiang, Lixin, Zhong, Xiaotian, Tam, May, Rizzo, Stacey J. Sukoff, Platt, Brian J., Dwyer, Jason M., Neal, Sarah, Pulito, Virginia L., Agostino, Michael J., Grauer, Steven M., Navarra, Rachel L., Kelley, Cody, Comery, Thomas A., Murrills, Richard J., Houslay, Miles D., Brandon, Nicholas J., Snyder, Solomon

Volltext

Pyroglutamate and O-Linked Glycan Determine Functional Production of Anti-IL17A and Anti-IL22 Peptide-Antibody Bispecific Genetic Fusions von Zhong, Xiaotian, Kieras, Elizabeth, Sousa, Eric, D'Antona, Aaron, Baber, J. Christian, He, Tao, Desharnais, Joel, Wood, Lauren, Luxenberg, Deborah, Stahl, Mark, Kriz, Ronald, Lin, Laura, Somers, Will, Fitz, Lori J., Wright, Jill F.

Volltext

Cetuximab and Cisplatin Show Different Combination Effect in Nasopharyngeal Carcinoma Cells Lines via Inactivation of EGFR/AKT Signaling Pathway von He, Xia, Xu, Lin, Ding, Kai, Huang, Teng, Zhang, Nan, Wu, Jing, Yin, Li, Gu, Jiajia, Cao, Haixia

Volltext

The Structure of the Lingo-1 Ectodomain, a Module Implicated in Central Nervous System Repair Inhibition von Mosyak, Lidia, Wood, Andrew, Dwyer, Brian, Buddha, Madhavan, Johnson, Mark, Aulabaugh, Ann, Zhong, Xiaotian, Presman, Eleonora, Benard, Susan, Kelleher, Kerry, Wilhelm, James, Stahl, Mark L., Kriz, Ron, Gao, Ying, Cao, Zixuan, Ling, Huai-Ping, Pangalos, Menelas N., Walsh, Frank S., Somers, William S.

Volltext

Regulation of Secreted Frizzled-related Protein-1 by Heparin von Zhong, Xiaotian, Desilva, Thamara, Lin, Laura, Bodine, Peter, Bhat, Ramesh A., Presman, Eleonora, Pocas, Jennifer, Stahl, Mark, Kriz, Ron

Volltext

Global burden of non-rheumatic valvular heart disease in older adults (60–89 years old), 1990–2019: Systematic analysis of the Global Burden of Disease Study 2019 von Dou, Zhili, Lai, Xuan, Zhong, Xiaotian, Hu, Suiyuan, Shi, Yanyan, Jia, Jinzhu

Volltext