Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR–Cas9 library von Zhu, Shiyou, Li, Wei, Liu, Jingze, Chen, Chen-Hao, Liao, Qi, Xu, Ping, Xu, Han, Xiao, Tengfei, Cao, Zhongzheng, Peng, Jingyu, Yuan, Pengfei, Brown, Myles, Liu, Xiaole Shirley, Wei, Wensheng

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Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL−/− clear cell renal carcinoma von Gao, Wenhua, Li, Wei, Xiao, Tengfei, Liu, Xiaole Shirley, Kaelin, William G.

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Topological analysis reveals a PD-L1-associated microenvironmental niche for Reed-Sternberg cells in Hodgkin lymphoma von Carey, Christopher D., Gusenleitner, Daniel, Lipschitz, Mikel, Roemer, Margaretha G.M., Stack, Edward C., Gjini, Evisa, Hu, Xihao, Redd, Robert, Freeman, Gordon J., Neuberg, Donna, Hodi, F. Stephen, Liu, Xiaole Shirley, Shipp, Margaret A., Rodig, Scott J.

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Inference of transcriptional regulation in cancers von Jiang, Peng, Matthew L. Freedman, Jun S. Liu, Xiaole Shirley Liu

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Protein Kinase C α Is a Central Signaling Node and Therapeutic Target for Breast Cancer Stem Cells von Tam, Wai Leong, Lu, Haihui, Buikhuisen, Joyce, Soh, Boon Seng, Lim, Elgene, Reinhardt, Ferenc, Wu, Zhenhua Jeremy, Krall, Jordan A., Bierie, Brian, Guo, Wenjun, Chen, Xi, Liu, Xiaole Shirley, Brown, Myles, Lim, Bing, Weinberg, Robert A.

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Estrogen receptor prevents p53-dependent apoptosis in breast cancer von Bailey, Shannon T, Shin, Hyunjin, Westerling, Thomas, Liu, Xiaole Shirley, Brown, Myles

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Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation von Hsieh, Chen-Lin, Fei, Teng, Chen, Yiwen, Li, Tiantian, Gao, Yanfei, Wang, Xiaodong, Sun, Tong, Sweeney, Christopher J., Lee, Gwo-Shu Mary, Chen, Shaoyong, Balk, Steven P., Liu, Xiaole Shirley, Brown, Myles, Kantoff, Philip W.

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The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation von Chen, Shuzhen, Ma, Jian, Wu, Feizhen, Xiong, Li-Jun, Ma, Honghui, Xu, Wenqi, Lv, Ruitu, Li, Xiaodong, Villen, Judit, Gygi, Steven P, Liu, Xiaole Shirley, Shi, Yang

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Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia von Yashiro-Ohtani, Yumi, Wang, Hongfang, Zang, Chongzhi, Arnett, Kelly L, Bailis, Will, Ho, Yugong, Knoechel, Birgit, Lanauze, Claudia, Louis, Lumena, Forsyth, Katherine S, Chen, Sujun, Chung, Yoonjie, Schug, Jonathan, Blobel, Gerd A, Liebhaber, Stephen A, Bernstein, Bradley E, Blacklow, Stephen C, Liu, Xiaole Shirley, Aster, Jon C, Pear, Warren S

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A Comprehensive View of Nuclear Receptor Cancer Cistromes von QIANZI TANG, YIWEN CHEN, MEYER, Clifford, GEISTLINGER, Tim, LUPIEN, Mathieu, QIAN WANG, TAO LIU, YONG ZHANG, BROWN, Myles, XIAOLE SHIRLEY LIU

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Targeting epigenetic regulators for cancer therapy von Wee, Susan, Dhanak, Dash, Li, Haitao, Armstrong, Scott A., Copeland, Robert A., Sims, Robert, Baylin, Stephen B., Liu, Xiaole Shirley, Schweizer, Liang

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Identifying ChIP-seq enrichment using MACS von Feng, Jianxing, Liu, Tao, Qin, Bo, Zhang, Yong, Liu, Xiaole Shirley

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Abstract A19: Network analysis of gene essentiality in CRISPR screens von Jiang, Peng, Liu, Xiaole Shirley

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Abstract 4966: Characteristics of immune repertoires in early lung cancer patients von Wang, Jin, Hu, Xihao, Zhang, Peng, Liu, Xiaole Shirley

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Nucleosome dynamics define transcriptional enhancers von He, Housheng Hansen, Bailey, Shannon T, Lupien, Mathieu, Wei, Gang, Zhao, Keji, Brown, Myles, Mieczkowski, Piotr, Xu, Kexin, Meyer, Clifford A, Zhang, Yong, Lieb, Jason D, Liu, X Shirley, Shin, Hyunjin, Wang, Qianben, Ni, Min

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CRISPR-DO for genome-wide CRISPR design and optimization von Ma, Jian, Köster, Johannes, Qin, Qian, Hu, Shengen, Li, Wei, Chen, Chenhao, Cao, Qingyi, Wang, Jinzeng, Mei, Shenglin, Liu, Qi, Xu, Han, Liu, Xiaole Shirley

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Enhanced Efficacy of Simultaneous PD-1 and PD-L1 Immune Checkpoint Blockade in High-Grade Serous Ovarian Cancer von Wan, Changxin, Keany, Matthew P., Dong, Han, Al-Alem, Linah F., Pandya, Unnati M., Lazo, Suzan, Boehnke, Karsten, Lynch, Katherine N., Xu, Rui, Zarrella, Dominique T., Gu, Shengqing, Cejas, Paloma, Lim, Klothilda, Long, Henry W., Elias, Kevin M., Horowitz, Neil S., Feltmate, Colleen M., Muto, Michael G., Worley, Michael J., Berkowitz, Ross S., Matulonis, Ursula A., Nucci, Marisa R., Crum, Christopher P., Rueda, Bo R., Brown, Myles, Liu, Xiaole Shirley, Hill, Sarah J.

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Association of host immune signatures with response to immunotherapy-based regimens in patients with metastatic renal cell carcinoma (mRCC) von Saad, Eddy, Labaki, Chris, Saliby, Renee Maria, Song, Li, Bakouny, Ziad, Pan, Wenting, Wall, McKenzy, Lee, Gwo-Shu Mary, Braun, David A., Liu, Xiaole Shirley, Choueiri, Toni K.

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Evaluation of immune repertoire inference methods from RNA-seq data von Hu, Xihao, Zhang, Jian, Liu, Jun S, Li, Bo, Liu, Xiaole Shirley

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CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells von Kumar, Sushil, Zeng, Zexian, Bagati, Archis, Tay, Rong En, Sanz, Lionel A., Hartono, Stella R., Ito, Yoshinaga, Abderazzaq, Fieda, Hatchi, Elodie, Jiang, Peng, Cartwright, Adam N. R., Olawoyin, Olamide, Mathewson, Nathan D., Pyrdol, Jason W., Li, Mamie Z., Doench, John G., Booker, Matthew A., Tolstorukov, Michael Y., Elledge, Stephen J., Chedin, Frederic, Liu, X. Shirley, Wucherpfennig, Kai W.

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