STING is Expressed by Hodgkin and Reed Sternberg (HRS) Cells in a Subset of Classical Hodgkin Lymphoma (cHL) and Correlates with Tumor Microenvironment and Immune Response von Xagoraris, I., Mulder, T., Stathopoulou, K., Xyderou, P., Andersson, M., Palma, M., Rassidakis, G.

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Activation of the Novel Tumor Suppressor SAMHD1 Inhibits Cell Growth and Induces Interferon‐beta (IFN‐β) Gene Expression in Classical Hodgkin Lymphoma (cHL) von Xagoraris, I., Stathopoulou, K., Binh Nordentoft, C. An, Xyderou, P., Kurzay, A., Lundqvist, A., Herold, N., Rassidakis, G.

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PB2171: THE NOVEL CSN5/JAB1 INHIBITOR CSN5I‐3 SUPPRESSES CELL GROWTH AND UPREGULATES GENE EXPRESSION OF TYPE‐I INTERFERONS (IFN) IN ANAPLASTIC LARGE CELL LYMPHOMA (ALCL) von Xagoraris, I., Kokaraki, G., Stathopoulou, K., Claret, F. X., Drakos, E., Rassidakis, G. Z.

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TREATMENT STRATEGIES AND PROGNOSTIC FACTORS FOR THE OUTCOME OF PATIENTS WITH HODGKIN LYMPHOMA EXPERIENCING VERY LATE RELAPSES AFTER CHEMOTHERAPY ± RADIOTHERAPY von Vassilakopoulos, T. P., Liaskas, A., Rizzuto, G., Symeonidis, A., Palma, M., Angelopoulou, M. K., Giatra, C., Spanoudakis, E., Oikonomopoulos, P., Kondopidou, F. N., Dimou, M., Musseti, A., Xagoraris, I., Siakantaris, M., Panitsas, F., Asimakopoulos, J., Arapaki, M., Chatzidimitriou, C., Belia, M., Sachanas, S., Korkolopoulou, P., Cabras, A., Variami, E., Panayotidis, P., Bakiri, M., Karmiris, T., Rassidakis, G., Corradini, P., Pangalis, G. A., Viviani, S.

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P1283: CIRCULATING IMMUNE CELLS IN CLASSICAL HODGKIN LYMPHOMA IN RELATION TO TUMOR BURDEN AND TREATMENT von Mulder, T. A., Andersson, M. L., Heimersson, K., Xagoraris, I., Wahlin, B. E., Rassidakis, G., Hansson, L., Palma, M.

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P1304: THE NOVEL TUMOR SUPPRESSOR SAMHD1 CONTRIBUTES TO ANTI‐TUMOR RESPONSES IN A CGAS‐STING‐DEPENDENT OR INDEPENDENT PATHWAY IN HODGKIN LYMPHOMA (HL) von Xagoraris, I., Kokaraki, G., Stathopoulou, K., Xyderou, P., Kurzay, A., Herold, N., Lundqvist, A., Rassidakis, G. Z.

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Modulation of the CGAS-Sting Anti-Tumor Immune Response Pathway in an NF-KB-Dependent or -Independent Manner As a Potential Therapeutic Target in Classical Hodgkin Lymphoma (cHL) von Xagoraris, Ioanna, Stathopoulou, Konstantina, Xyderou, Persa, Palma, Marzia, Drakos, Elias, Vassilakopoulos, Theodoros P., Rassidakis, George Z.

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The NPM-ALK Oncogenic Kinase Suppresses CGAS-Sting-Associated Anti-Tumor Immune Responses through STAT3 Activation in Anaplastic Large Cell Lymphoma (ALCL) von Xagoraris, Ioanna, Kokaraki, Georgia, Plastira, Christina, Stathopoulou, Konstantina, Leventaki, Vasiliki, Drakos, Elias, Medeiros, Jeffrey, Österborg, Anders, Rassidakis, George Z.

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17th International Conference on Malignant Lymphoma, Palazzo dei Congressi, Lugano, Switzerland, 13 - 17 June, 2023 von Xagoraris, I, Mulder, T, Stathopoulou, K, Xyderou, P, Andersson, M, Palma, M, Rassidakis, G

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Trametinib and Dabrafenib in histiocytic sarcoma transdifferentiated from chronic lymphocytic leukemia with a K-RAS and a unique BRAF mutation von Rassidakis, George Z., Stromberg, Olga, Xagoraris, Ioanna, Jatta, Kenbugul, Sonnevi, Kristina

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Expression of the novel tumour suppressor sterile alpha motif and HD domain‐containing protein 1 is an independent adverse prognostic factor in classical Hodgkin lymphoma von Xagoraris, Ioanna, Vassilakopoulos, Theodoros P., Drakos, Elias, Angelopoulou, Maria K., Panitsas, Fotios, Herold, Nikolas, Medeiros, L. Jeffrey, Giakoumis, Xanthoula, Pangalis, Gerassimos A., Rassidakis, George Z.

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Mutations of the Novel Tumor Suppressor Gene SAMHD1 Are Frequent and Correlate with Decreased Protein Expression in Peripheral T-Cell Lymphomas (PTCL) von Kokaraki, Georgia, Xagoraris, Ioanna, Farrajota Neves Da Silva, Pedro, Sutton, Lesley Ann, Maia Falcão, Raul, Estefano Santana de Souza, Jorge, Österborg, Anders, Wirta, Valtteri, Rosenquist Brandell, Richard, Rassidakis, Georgios Z.

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Establishment and characterization of a novel breast implant-associated anaplastic large cell lymphoma cell line and PDX model (BIA-XR1) with a unique KRAS mutation von Xagoraris, Ioanna, Stathopoulou, Konstantina, Aulerio, Roberta D', He, Minghui, Ketscher, Anett, Jatta, Kenbugul, de Flon, Felix Haglund, Barbany, Gisela, Rosenquist, Richard, Westerberg, Lisa S., Rassidakis, George Z.

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The Novel Tumor Suppressor SAMHD1 Is Differentially Expressed and Partly Regulated By MYC in Peripheral T-Cell Lymphomas (PTCL) von Farrajota Neves Da Silva, Pedro, Tsesmetzis, Nikolaos, Xagoraris, Ioanna, Wasik, Agata Magdalena, Kokaraki, Georgia, Tzoras, Evangelos, Österborg, Anders, Sander, Birgitta, Herold, Nikolas, Rassidakis, George

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Immune Biomarkers in the Peripheral Blood and Tumor Microenvironment of Classical Hodgkin Lymphoma Patients in Relation to Tumor Burden and Response to Treatment von Mulder, Tom A., Andersson, Maria L., Peña‐Pérez, Lucía, Heimersson, Kia, Xagoraris, Ioanna, Wahlin, Björn E., Månsson, Robert, Hansson, Lotta, Rassidakis, Georgios, Palma, Marzia

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Sting Is Commonly and Differentially Expressed in T- and Nk-Cell but Not B-Cell Non-Hodgkin Lymphomas von Xagoraris, Ioanna, Farrajota Neves da Silva, Pedro, Kokaraki, Georgia, Stathopoulou, Konstantina, Wahlin, Björn, Österborg, Anders, Herold, Nikolas, Ng, Siok-Bian, Medeiros, L Jeffrey, Drakos, Elias, Sander, Birgitta, Rassidakis, George Z

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PS1082 PROGNOSTIC SIGNIFICANCE OF SAMHD1 EXPRESSION IN DIFFUSE LARGE B‐CELL LYMPHOMA (DLBCL) von Xagoraris, I., Herold, N., Sander, B., Smedby, K. Ekström, Rassidakis, G.

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SAMHD1 Is Variably Expressed in Mantle Cell Lymphoma and Correlated to SOX11 but Not to Survival von Wasik, AM, Marin, E, Merrien, M, Rodrigues, JDM, Lord, M, Xagoraris, I, Christensson, B, Rassidakis, G, Jerkeman, M, Ek, S

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Expression of Granzyme B and Perforin in Multiple Myeloma von Xagoraris, Iordanis, Paterakis, George, Zolota, Bassiliki, Zikos, Panagiotis, Maniatis, Alice, Mouzaki, Athanasia

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Chronic mild stress impact: Are females more vulnerable? von Dalla, C., Antoniou, K., Drossopoulou, G., Xagoraris, M., Kokras, N., Sfikakis, A., Papadopoulou-Daifoti, Z.

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