Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase von Huang, Wei-Sheng, Liu, Shuangying, Zou, Dong, Thomas, Mathew, Wang, Yihan, Zhou, Tianjun, Romero, Jan, Kohlmann, Anna, Li, Feng, Qi, Jiwei, Cai, Lisi, Dwight, Timothy A, Xu, Yongjin, Xu, Rongsong, Dodd, Rory, Toms, Angela, Parillon, Lois, Lu, Xiaohui, Anjum, Rana, Zhang, Sen, Wang, Frank, Keats, Jeffrey, Wardwell, Scott D, Ning, Yaoyu, Xu, Qihong, Moran, Lauren E, Mohemmad, Qurish K, Jang, Hyun Gyung, Clackson, Tim, Narasimhan, Narayana I, Rivera, Victor M, Zhu, Xiaotian, Dalgarno, David, Shakespeare, William C

Volltext

Surface mercapto engineered magnetic Fe₃O₄ nanoadsorbent for the removal of mercury from aqueous solutions von Pan, Shengdong, Shen, Haoyu, Xu, Qihong, Luo, Jian, Hu, Meiqin

Volltext

Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance von Zhou, Tianjun, Commodore, Lois, Huang, Wei-Sheng, Wang, Yihan, Thomas, Mathew, Keats, Jeff, Xu, Qihong, Rivera, Victor M, Shakespeare, William C, Clackson, Tim, Dalgarno, David C, Zhu, Xiaotian

Volltext

9-(Arenethenyl)purines as Dual Src/Abl Kinase Inhibitors Targeting the Inactive Conformation: Design, Synthesis, and Biological Evaluation von Huang, Wei-Sheng, Zhu, Xiaotian, Wang, Yihan, Azam, Mohammad, Wen, David, Sundaramoorthi, Raji, Thomas, R. Mathew, Liu, Shuangying, Banda, Geetha, Lentini, Scott P, Das, Sasmita, Xu, Qihong, Keats, Jeff, Wang, Frank, Wardwell, Scott, Ning, Yaoyu, Snodgrass, Joseph T, Broudy, Marc I, Russian, Karin, Daley, George Q, Iuliucci, John, Dalgarno, David C, Clackson, Tim, Sawyer, Tomi K, Shakespeare, William C

Volltext

Simultaneous determination of 11 quinolone residues in freshwater fish samples by magnetic solid‐extraction coupled to liquid chromatography‐tandem mass spectrometry von Pan, Shengdong, Xu, Qihong, Guo, Yanbo, Wang, Li

Volltext

Adsorption Studies on Phosphate by Amino-functionalized Nano-size Composite Materials von Zhang, Yun, Xi, Xiaoqing, Xu, Shanni, Zhou, Junchen, Zhou, Jinjin, Xu, Qihong, Shen, Haoyu

Volltext

Identification, synthesis, and biological evaluation of novel pyrazoles as low molecular weight luteinizing hormone receptor agonists von Jorand-Lebrun, Catherine, Brondyk, Bill, Lin, Jing, Magar, Sharad, Murray, Robert, Reddy, Adulla, Shroff, Hitesh, Wands, Greg, Weiser, Weishui, Xu, Qihong, McKenna, Sean, Brugger, Nadia

Volltext

Discovery of 5-(arenethynyl) hetero-monocyclic derivatives as potent inhibitors of BCR–ABL including the T315I gatekeeper mutant von Thomas, Mathew, Huang, Wei-Sheng, Wen, David, Zhu, Xiaotian, Wang, Yihan, Metcalf, Chester A., Liu, Shuangying, Chen, Ingrid, Romero, Jan, Zou, Dong, Sundaramoorthi, Raji, Li, Feng, Qi, Jiwei, Cai, Lisi, Zhou, Tianjun, Commodore, Lois, Xu, Qihong, Keats, Jeff, Wang, Frank, Wardwell, Scott, Ning, Yaoyu, Snodgrass, Joseph T., Broudy, Marc I., Russian, Karin, Iuliucci, John, Rivera, Victor M., Sawyer, Tomi K., Dalgarno, David C., Clackson, Tim, Shakespeare, William C.

Volltext

Enhancing flotation separation of chalcopyrite and galena by the surface synergism between sodium sulfite and sodium lignosulfonate von Liu, Mengfei, Zhang, Chenyang, Hu, Bo, Sun, Zhongmei, Xu, Qihong, Wen, Jian, Xiao, Jun, Dong, Yanhong, Gan, Min, Sun, Wei, Zhu, Jianyu, Chen, Daixiong

Volltext

Abstract 1555: Enhanced HER2-dependent immune activation by margetuximab, an investigational Fc-engineered anti-HER2 mAb, supports combination with checkpoint blockade von Zhang, Xiaoyu, Li, Haiquan, Yang, Yinhua, Xu, Qihong, Kaufman, Tom, Smith, Doug, Nordstrom, Jeffrey, Bonvini, Ezio, Moore, Paul

Volltext

AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance von O'Hare, Thomas, Shakespeare, William C., Zhu, Xiaotian, Eide, Christopher A., Rivera, Victor M., Wang, Frank, Adrian, Lauren T., Zhou, Tianjun, Huang, Wei-Sheng, Xu, Qihong, Metcalf, Chester A., Tyner, Jeffrey W., Loriaux, Marc M., Corbin, Amie S., Wardwell, Scott, Ning, Yaoyu, Keats, Jeffrey A., Wang, Yihan, Sundaramoorthi, Raji, Thomas, Mathew, Zhou, Dong, Snodgrass, Joseph, Commodore, Lois, Sawyer, Tomi K., Dalgarno, David C., Deininger, Michael W.N., Druker, Brian J., Clackson, Tim

Volltext

B-cell delivered gene transfer of human S-Ag-Ig fusion protein protects from experimental autoimmune uveitis von Liang, Wei, Karabekian, Zaruhi, Xu, Qihong, Viley, Angelia M., Scott, David W.

Volltext

Discovery of 3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a Potent, Orally Active Pan-I... von Huang, Wei-Sheng, Metcalf, Chester A, Sundaramoorthi, Raji, Wang, Yihan, Zou, Dong, Thomas, R. Mathew, Zhu, Xiaotian, Cai, Lisi, Wen, David, Liu, Shuangying, Romero, Jan, Qi, Jiwei, Chen, Ingrid, Banda, Geetha, Lentini, Scott P, Das, Sasmita, Xu, Qihong, Keats, Jeff, Wang, Frank, Wardwell, Scott, Ning, Yaoyu, Snodgrass, Joseph T, Broudy, Marc I, Russian, Karin, Zhou, Tianjun, Commodore, Lois, Narasimhan, Narayana I, Mohemmad, Qurish K, Iuliucci, John, Rivera, Victor M, Dalgarno, David C, Sawyer, Tomi K, Clackson, Tim, Shakespeare, William C

Volltext

Novel N9-arenethenyl purines as potent dual Src/Abl tyrosine kinase inhibitors von Wang, Yihan, Shakespeare, William C., Huang, Wei-Sheng, Sundaramoorthi, Raji, Lentini, Scott, Das, Sasmita, Liu, Shuangying, Banda, Geeta, Wen, David, Zhu, Xiaotian, Xu, Qihong, Keats, Jeffrey, Wang, Frank, Wardwell, Scott, Ning, Yaoyu, Snodgrass, Joseph T., Broudy, Mark I., Russian, Karin, Dalgarno, David, Clackson, Tim, Sawyer, Tomi K.

Volltext

Abstract 554: Tumor-antigen 5T4-dependent activation of the CD137 costimulatory pathway by bispecific 5T4 x CD137 x CD137 TRIDENT™ molecules von Liu, Liqin, Huang, Ling, Long, Vatana, Yang, Yinhua, Burns, Robert, Li, Jonathan, DiChiara, Jennifer, Xu, Qihong, Whiddon, Arin, Lam, Chia-Ying K, Tamura, Jim, Ciccarone, Valentina, Johnson, Syd, Bonvini, Ezio, Moore, Paul

Volltext

Functionally Biased D2R Antagonists: Targeting the β‑Arrestin Pathway to Improve Antipsychotic Treatment von Weïwer, Michel, Xu, Qihong, Gale, Jennifer P, Lewis, Michael, Campbell, Arthur J, Schroeder, Frederick A, Van de Bittner, Genevieve C, Walk, Michelle, Amaya, Aldo, Su, Ping, D̵ordevic, Luka, Sacher, Joshua R, Skepner, Adam, Fei, David, Dennehy, Kelly, Nguyen, Shannon, Faloon, Patrick W, Perez, Jose, Cottrell, Jeffrey R, Liu, Fang, Palmer, Michelle, Pan, Jen Q, Hooker, Jacob M, Zhang, Yan-Ling, Scolnick, Edward, Wagner, Florence F, Holson, Edward B

Volltext

Crystal Structure of the T315I Mutant of Abl Kinase von Zhou, Tianjun, Parillon, Lois, Li, Feng, Wang, Yihan, Keats, Jeff, Lamore, Sarah, Xu, Qihong, Shakespeare, William, Dalgarno, David, Zhu, Xiaotian

Volltext

Crystal structure of the T315I mutant of AbI kinase von Zhou, Tianjun, Parillon, Lois, Li, Feng, Wang, Yihan, Keats, Jeff, Lamore, Sarah, Xu, Qihong, Shakespeare, William, Dalgarno, David, Zhu, Xiaotian

Volltext

Surface mercapto engineered magnetic Fe sub(3O) sub(4) nanoadsorbent for the removal of mercury from aqueous solutions von Pan, Shengdong, Shen, Haoyu, Xu, Qihong, Luo, Jian, Hu, Meiqin

Volltext

Surface mercapto engineered magnetic Fe 3O 4 nanoadsorbent for the removal of mercury from aqueous solutions von Pan, Shengdong, Shen, Haoyu, Xu, Qihong, Luo, Jian, Hu, Meiqin

Volltext