Molecular Basis of Sphingosine Kinase 1 Substrate Recognition and Catalysis von Wang, Zhulun, Min, Xiaoshan, Xiao, Shou-Hua, Johnstone, Sheree, Romanow, William, Meininger, David, Xu, Haoda, Liu, Jinsong, Dai, Jessica, An, Songzhu, Thibault, Stephen, Walker, Nigel

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Autonomous IL-36R signaling in neutrophils activates potent antitumor effector functions von Roy, Sumedha, Fitzgerald, Karen, Lalani, Almin, Lai, Chin-Wen, Kim, Aeryon, Kim, Jennie, Ou, Peiqi, Mirsoian, Annie, Liu, Xian, Ramrakhiani, Ambika, Zhao, Huiren, Zhou, Hong, Xu, Haoda, Meisen, Hans, Li, Chi-Ming, Lugt, Bryan Vander, Thibault, Steve, Tinberg, Christine E, DeVoss, Jason, Egen, Jackson, Wu, Lawren C, Noubade, Rajkumar

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Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors von Walker, Nigel P. C, Perlmann, Thomas, Wang, Zhulun, Benoit, Gérard, Liu, Jinsong, Prasad, Srividya, Aarnisalo, Piia, Liu, Xiaohong, Xu, Haoda

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Identification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo von Motani, Alykhan, Wang, Zhulun, Conn, Marion, Siegler, Karen, Zhang, Ying, Liu, Qingxiang, Johnstone, Sheree, Xu, Haoda, Thibault, Steve, Wang, Yingcai, Fan, Pingchen, Connors, Richard, Le, Hoa, Xu, Guifen, Walker, Nigel, Shan, Bei, Coward, Peter

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Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor von Min, Xiaoshan, Yie, Junming, Wang, Jinghong, Chung, Ben C, Huang, Ching-Shin, Xu, Haoda, Yang, Jie, Deng, Liying, Lin, Joanne, Chen, Qing, Abbott, Christina M, Gundel, Caroline, Thibault, Stephen A, Meng, Tina, Bates, Darren L, Lloyd, David J, Véniant, Murielle M, Wang, Zhulun

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Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH) von Min, Xiaoshan, Thibault, Stephen T, Porter, Amy C, Gustin, Darin J, Carlson, Timothy J, Xu, Haoda, Lindstrom, Michelle, Xu, Guifen, Uyeda, Craig, Ma, Zhihua, Li, Yihong, Kayser, Frank, Walker, Nigel P.C, Wang, Zhulun

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TWEAK, a New Secreted Ligand in the Tumor Necrosis Factor Family That Weakly Induces Apoptosis von Chicheportiche, Yves, Bourdon, Paul R., Xu, Haoda, Hsu, Yen-Ming, Scott, Hamish, Hession, Catherine, Garcia, Irene, Browning, Jeffrey L.

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Inverse design of highly-efficient and broadband polarization beam splitter on SOI platform von Xu, Haoda, Tian, Ye, Li, Yan, Huang, Dongmei, Zhang, Xiaowei

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Broadband and Compact Silicon Multimode Waveguide Bends Based on Hybrid Shape Optimization von Liao, Junpeng, Tian, Ye, Yang, Zirong, Xu, Haoda, Dai, Tingge, Zhang, Xiaowei, Kang, Zhe

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Distinctive molecular inhibition mechanisms for selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 von Tu, Hua, Powers, Jay P., Liu, Jinsong, Ursu, Stefania, Sudom, Athena, Yan, Xuelei, Xu, Haoda, Meininger, David, DeGraffenreid, Michael, He, Xiao, Jaen, Juan C., Sun, Daqing, Labelle, Marc, Yamamoto, Hiroshi, Shan, Bei, Walker, Nigel P.C., Wang, Zhulun

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Structure-Guided Design, Synthesis, and Evaluation of Guanine-Derived Inhibitors of the eIF4E mRNA–Cap Interaction von Chen, Xiaoqi, Kopecky, David J, Mihalic, Jeff, Jeffries, Shawn, Min, Xiaoshan, Heath, Julie, Deignan, Jeff, Lai, SuJen, Fu, Zice, Guimaraes, Cristiano, Shen, Shanling, Li, Shyun, Johnstone, Sheree, Thibault, Stephen, Xu, Haoda, Cardozo, Mario, Shen, Wang, Walker, Nigel, Kayser, Frank, Wang, Zhulun

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T2384, a Novel Antidiabetic Agent with Unique Peroxisome Proliferator-activated Receptor γ Binding Properties von Li, Yang, Wang, Zhulun, Furukawa, Noboru, Escaron, Patrick, Weiszmann, Jennifer, Lee, Gary, Lindstrom, Michelle, Liu, Jinsong, Liu, Xiaohong, Xu, Haoda, Plotnikova, Olga, Prasad, Vidya, Walker, Nigel, Learned, R. Marc, Chen, Jin-Long

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Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4 von Wang, Yingcai, Connors, Richard, Fan, Pingchen, Wang, Xiaodong, Wang, Zhongyu, Liu, Jiwen, Kayser, Frank, Medina, Julio C, Johnstone, Sheree, Xu, Haoda, Thibault, Stephen, Walker, Nigel, Conn, Marion, Zhang, Ying, Liu, Qingxiang, Grillo, Mark P, Motani, Alykhan, Coward, Peter, Wang, Zhulun

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A Significant Fraction of Functional SecA Is Permanently Embedded in the Membrane von Chen, Xianchuan, Xu, Haoda, Tai, Phang C.

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Structural Characterization and Pharmacodynamic Effects of an Orally Active 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor von Hale, Clarence, Véniant, Murielle, Wang, Zhulun, Chen, Michelle, McCormick, Jocelyn, Cupples, Rod, Hickman, Dean, Min, Xiaoshan, Sudom, Athena, Xu, Haoda, Matsumoto, Guy, Fotsch, Christopher, St. Jean, David J. Jr, Wang, Minghan

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T2384, a Novel Antidiabetic Agent with Unique Peroxisome Proliferator-activated Receptor γ Binding Properties von Yang Li, Zhulun Wang, Noboru Furukawa, Patrick Escaron, Jennifer Weiszmann, Gary Lee, Michelle Lindstrom, Jinsong Liu, Xiaohong Liu, Haoda Xu, Olga Plotnikova, Vidya Prasad, Nigel Walker, R. Marc Learned, Jin-Long Chen

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A significant fraction of functional SecA is permanently embedded in the membrane. SecA cycling on and off the membrane is not essential during protein translocation von Chen, X, Xu, H, Tai, P C

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On protein translocation across bacterial cytoplasmic membranes von TAI, P. C, JIANPING LIAN, NIAN-JUN YU, FANDL, J, HAODA XU, VIDUGIRIENE, J

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Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1 von Tu, Hua, Powers, Jay P, Liu, Jinsong, Ursu, Stefania, Sudom, Athena, Yan, Xuelei, Xu, Haoda, Meininger, David, Degraffenreid, Michael, He, Xiao, Jaen, Juan C, Sun, Daqing, Labelle, Marc, Yamamoto, Hiroshi, Shan, Bei, Walker, Nigel P C, Wang, Zhulun

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Structural characterization and pharmacodynamic effects of an orally active 11beta-hydroxysteroid dehydrogenase type 1 inhibitor von Hale, Clarence, Véniant, Murielle, Wang, Zhulun, Chen, Michelle, McCormick, Jocelyn, Cupples, Rod, Hickman, Dean, Min, Xiaoshan, Sudom, Athena, Xu, Haoda, Matsumoto, Guy, Fotsch, Christopher, St Jean, Jr, David J, Wang, Minghan

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