Structural Analyses Reveal Phosphatidyl Inositols as Ligands for the NR5 Orphan Receptors SF-1 and LRH- 1 von Krylova, Irina N., Sablin, Elena P., Moore, Jamie, Xu, Robert X., Waitt, Gregory M., MacKay, J. Andrew, Juzumiene, Dalia, Bynum, Jane M., Madauss, Kevin, Montana, Valerie, Lebedeva, Lioudmila, Suzawa, Miyuki, Williams, Jon D., Williams, Shawn P., Guy, Rodney K., Thornton, Joseph W., Fletterick, Robert J., Willson, Timothy M., Ingraham, Holly A.

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Atomic Structure of PDE4: Insights into Phosphodiesterase Mechanism and Specificity von Xu, Robert X., Hassell, Anne M., Vanderwall, Dana, Lambert, Millard H., Holmes, William D., Luther, Michael A., Rocque, Warren J., Milburn, Michael V., Zhao, Yingdong, Ke, Hengming, Nolte, Robert T.

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Identification and Characterization of 4-Chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a Selective and Irreversible Peroxisome Proliferator-Activat... von Shearer, Barry G, Wiethe, Robert W, Ashe, Adam, Billin, Andrew N, Way, James M, Stanley, Thomas B, Wagner, Craig D, Xu, Robert X, Leesnitzer, Lisa M, Merrihew, Raymond V, Shearer, Todd W, Jeune, Michael R, Ulrich, John C, Willson, Timothy M

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Crystal Structures of the Catalytic Domain of Phosphodiesterase 4B Complexed with AMP, 8-Br-AMP, and Rolipram von Xu, Robert X, Rocque, Warren J, Lambert, Millard H, Vanderwall, Dana E, Luther, Michael A, Nolte, Robert T

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Substituted 2-[(4-Aminomethyl)phenoxy]-2-methylpropionic Acid PPARα Agonists. 1. Discovery of a Novel Series of Potent HDLc Raising Agents von Sierra, Michael L, Beneton, Véronique, Boullay, Anne-Bénédict, Boyer, Thierry, Brewster, Andrew G, Donche, Frédéric, Forest, Marie-Claire, Fouchet, Marie-Hélène, Gellibert, Françoise J, Grillot, Didier A, Lambert, Millard H, Laroze, Alain, Le Grumelec, Christelle, Linget, Jean Michel, Montana, Valerie G, Nguyen, Van-Loc, Nicodème, Edwige, Patel, Vipul, Penfornis, Annie, Pineau, Olivier, Pohin, Danig, Potvain, Florent, Poulain, Géraldine, Ruault, Cécile Bertho, Saunders, Michael, Toum, Jérôme, Xu, H. Eric, Xu, Robert X, Pianetti, Pascal M

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Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: The discovery of GW0385 von Miller, John F., Andrews, C. Webster, Brieger, Michael, Furfine, Eric S., Hale, Michael R., Hanlon, Mary H., Hazen, Richard J., Kaldor, Istvan, McLean, Ed W., Reynolds, David, Sammond, Douglas M., Spaltenstein, Andrew, Tung, Roger, Turner, Elizabeth M., Xu, Robert X., Sherrill, Ronald G.

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Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARγ partial agonist von Sime, Mairi, Allan, Amanda C., Chapman, Paul, Fieldhouse, Charlotte, Giblin, Gerard M.P., Healy, Mark P., Lambert, Millard H., Leesnitzer, Lisa M., Lewis, Ann, Merrihew, Raymond V., Rutter, Richard A., Sasse, Rosemary, Shearer, Barry G., Wilson, Timothy M., Xu, Robert X., Virley, David J.

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Solution Structure of the Amino-Terminal Fragment of Urokinase-Type Plasminogen Activator von Hansen, Andrew P, Petros, Andrew M, Meadows, Robert P, Nettesheim, David G, Mazar, Andrew P, Olejniczak, Edward T, Xu, Robert X, Pederson, Terry M, Henkin, Jack, Fesik, Stephen W

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Discovery of a novel class of PPARδ partial agonists von Shearer, Barry G., Patel, Hari S., Billin, Andrew N., Way, James M., Winegar, Deborah A., Lambert, Millard H., Xu, Robert X., Leesnitzer, Lisa M., Merrihew, Raymond V., Huet, Stephane, Willson, Timothy M.

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NMR Determination of the Structures of Peroxycobalt(III) Bleomycin and Cobalt(III) Bleomycin, Products of the Aerobic Oxidation of Cobalt(II) Bleomycin by Dioxygen von Xu, Robert X, Nettesheim, David, Otvos, James D, Petering, David H

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Phenoxyacetic acids as PPARδ partial agonists: Synthesis, optimization, and in vivo efficacy von Evans, Karen A., Shearer, Barry G., Wisnoski, David D., Shi, Dongchuan, Sparks, Steven M., Sternbach, Daniel D., Winegar, Deborah A., Billin, Andrew N., Britt, Christy, Way, James M., Epperly, Andrea H., Leesnitzer, Lisa M., Merrihew, Raymond V., Xu, Robert X., Lambert, Millard H., Jin, Jian

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NMR Structure of a Protein Kinase C-γ Phorbol-Binding Domain and Study of Protein−Lipid Micelle Interactions von Xu, Robert X, Pawelczyk, Tadeucz, Xia, Tai-He, Brown, Stephen C

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Crystallization of Cyclic Nucleotide Phosphodiesterases von Lugnier, Claire

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Heteronuclear 3D NMR studies of water bound to an FK506 binding protein/immunosuppressant complex von Xu, Robert X, Meadows, Robert P, Fesik, Stephen W

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A Structural Basis for Constitutive Activity in the Human CAR/RXRα Heterodimer von Xu, Robert X., Lambert, Millard H., Wisely, Bruce B., Warren, Erin N., Weinert, Emily E., Waitt, Gregory M., Williams, Jon D., Collins, Jon L., Moore, Linda B., Willson, Timothy M., Moore, John T.

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Oxidative stress induced by a copper-thiosemicarbazone complex von Byrnes, Robert W, Mohan, Madan, Antholine, William E, Xu, Robert X, Petering, David H

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Three-dimensional structure of the FK506 binding protein/ascomycin complex in solution by heteronuclear three- and four-dimensional NMR von Meadows, Robert P, Nettesheim, David G, Xu, Robert X, Olejniczak, Edward T, Petros, Andrew M, Holzman, Thomas F, Severin, Jean, Gubbins, Earl, Smith, Harriet, Fesik, Stephen W

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Corrigendum to “Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARγ partial agonist” [Bioorg. Med. Chem. Lett. 21 (2011) 5568–5572] von Sime, Mairi, Allan, Amanda C., Chapman, Paul, Fieldhouse, Charlotte, Giblin, Gerard M.P., Healy, Mark P., Lambert, Millard H., Leesnitzer, Lisa M., Lewis, Ann, Merrihew, Raymond V., Rutter, Richard A., Sasse, Rosemary, Shearer, Barry G., Willson, Timothy M., Xu, Robert X., Virley, David J.

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Genome Duplications and Other Features in 12 Mb of DNA Sequence from Human Chromosome 16p and 16q von Loftus, Brendan J., Kim, Ung-Jin, Sneddon, Victoria P., Kalush, Francis, Brandon, Rhonda, Fuhrmann, Joyce, Mason, Tanya, Crosby, Marie L., Barnstead, Mary, Cronin, Lisa, Deslattes Mays, Anne, Cao, Yicheng, Xu, Robert X., Kang, Hyung-Lyun, Mitchell, Steve, Eichler, Evan E., Harris, Peter C., Venter, J.Craig, Adams, Mark D.

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Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPAR[gamma] partial agonist von Sime, Mairi, Allan, Amanda C, Chapman, Paul, Fieldhouse, Charlotte, Giblin, Gerard MP, Healy, Mark P, Lambert, Millard H, Leesnitzer, Lisa M, Lewis, Ann, Merrihew, Raymond V, Rutter, Richard A, Sasse, Rosemary, Shearer, Barry G, Wilson, Timothy M, Xu, Robert X, Virley, David J

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