Environmental Enrichment Mitigates Cognitive Deficits in a Mouse Model of Alzheimer's Disease von Jankowsky, Joanna L, Melnikova, Tatiana, Fadale, Daniel J, Xu, Guilian M, Slunt, Hilda H, Gonzales, Victoria, Younkin, Linda H, Younkin, Steven G, Borchelt, David R, Savonenko, Alena V

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Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: Relationships to β-amyloid deposition and neurotransmitter abnormalities von Savonenko, Alena, Xu, Guilian M., Melnikova, Tatiana, Morton, Johanna L., Gonzales, Victoria, Wong, Molly P.F., Price, Donald L., Tang, Fai, Markowska, Alicja L., Borchelt, David R.

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Alzheimer's-Type Amyloidosis in Transgenic Mice Impairs Survival of Newborn Neurons Derived from Adult Hippocampal Neurogenesis von Verret, Laure, Jankowsky, Joanna L, Xu, Guilian M, Borchelt, David R, Rampon, Claire

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Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease von Pace, Michael C., Xu, Guilian, Fromholt, Susan, Howard, John, Crosby, Keith, Giasson, Benoit I., Lewis, Jada, Borchelt, David R.

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Multiple Factors Influence the Incubation Period of ALS Prion-like Transmission in SOD1 Transgenic Mice von Ayers, Jacob I, Xu, Guilian, Lu, Qing, Dillon, Kristy, Fromholt, Susan, Borchelt, David R

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Modeling the Competition between Misfolded Aβ Conformers That Produce Distinct Types of Amyloid Pathology in Alzheimer's Disease von Xu, Guilian, Fromholt, Susan, Borchelt, David R

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Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase von Jankowsky, Joanna L., Fadale, Daniel J., Anderson, Jeffrey, Xu, Guilian M., Gonzales, Victoria, Jenkins, Nancy A., Copeland, Neal G., Lee, Michael K., Younkin, Linda H., Wagner, Steven L., Younkin, Steven G., Borchelt, David R.

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A novel hollow iron nanoparticle system loading PEG-Fe3O4 with C5a receptor antagonist for breast cancer treatment von Yang, Hong, Li, Guiqing, Zhang, Ji, Zhao, Jing, Zhao, Yunpei, Wu, Yufei, Sun, Zihan, Song, Shuangshuang, Zou, Ying, Zou, Zhihao, Han, Xiao, Deng, Boshao, Wang, Lulu, Rao, Hang, Xu, Guilian, Wang, Shufeng, Guo, Sheng, Ding, Huanyu, Shi, Yan, Wu, Yuzhang, Chen, Jian

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Cytosolic proteins lose solubility as amyloid deposits in a transgenic mouse model of Alzheimer-type amyloidosis von Xu, Guilian, Stevens, Jr, Stanley M, Moore, Brenda D, McClung, Scott, Borchelt, David R

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Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy von Iradi, M. Carolina Gallego, Triplett, Judy C., Thomas, James D., Davila, Rachel, Crown, Anthony M., Brown, Hilda, Lewis, Jada, Swanson, Maurice S., Xu, Guilian, Rodriguez-Lebron, Edgardo, Borchelt, David R.

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Diversity in Aβ deposit morphology and secondary proteome insolubility across models of Alzheimer-type amyloidosis von Xu, Guilian, Fromholt, Susan E, Chakrabarty, Paramita, Zhu, Fanchao, Liu, Xuefei, Pace, Michael C, Koh, Jin, Golde, Todd E, Levites, Yona, Lewis, Jada, Borchelt, David R

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Impact of APOE genotype on prion-type propagation of tauopathy von Williams, Tristan, Ruiz, Alejandra Jolie, Ruiz, Angelica Maria, Vo, Quan, Tsering, Wangchen, Xu, Guilian, McFarland, Karen, Giasson, Benoit I, Sullivan, Patrick, Borchelt, David R, Chakrabarty, Paramita

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Unbiased screen reveals ubiquilin-1 and -2 highly associated with huntingtin inclusions von Rutherford, Nicola J, Lewis, Jada, Clippinger, Amy K, Thomas, Michael A, Adamson, Jennifer, Cruz, Pedro E, Cannon, Ashley, Xu, Guilian, Golde, Todd E, Shaw, Gerry, Borchelt, David R, Giasson, Benoit I

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Variation in the vulnerability of mice expressing human superoxide dismutase 1 to prion-like seeding: a study of the influence of primary amino acid sequence von Ayers, Jacob I, Xu, Guilian, Dillon, Kristy, Lu, Qing, Chen, Zhijuan, Beckman, John, Moreno-Romero, Alma K, Zamora, Diana L, Galaleldeen, Ahmad, Borchelt, David R

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Mapping superoxide dismutase 1 domains of non‐native interaction: roles of intra‐ and intermolecular disulfide bonding in aggregation von Wang, Jiou, Xu, Guilian, Borchelt, David R.

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Identification of proteins sensitive to thermal stress in human neuroblastoma and glioma cell lines von Xu, Guilian, Stevens, Jr, Stanley M, Kobeissy, Firas, Kobiessy, Firas, Brown, Hilda, McClung, Scott, Gold, Mark S, Borchelt, David R

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High Molecular Weight Complexes of Mutant Superoxide Dismutase 1: Age-Dependent and Tissue-Specific Accumulation von Wang, Jiou, Xu, Guilian, Borchelt, David R.

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Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: αB-crystallin modulates aggregation von Wang, Jiou, Xu, Guilian, Li, Hong, Gonzales, Victoria, Fromholt, David, Karch, Celeste, Copeland, Neal G., Jenkins, Nancy A., Borchelt, David R.

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Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed la... von Tebbenkamp, Andrew T.N., Green, Cameron, Xu, Guilian, Denovan-Wright, Eileen M., Rising, Aaron C., Fromholt, Susan E., Brown, Hilda H., Swing, Debbie, Mandel, Ronald J., Tessarollo, Lino, Borchelt, David R.

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Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology von Pace, Michael C, Xu, Guilian, Fromholt, Susan, Howard, John, Giasson, Benoit I, Lewis, Jada, Borchelt, David R

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