Development of a Simple In Vitro Assay To Identify and Evaluate Nucleotide Analogs against SARS-CoV-2 RNA-Dependent RNA Polymerase von Lu, Gaofei, Zhang, Xi, Zheng, Weinan, Sun, Jialei, Hua, Lan, Xu, Lan, Chu, Xin-Jie, Ding, Sheng, Xiong, Wen

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Discovery of RG7388, a Potent and Selective p53–MDM2 Inhibitor in Clinical Development von Ding, Qingjie, Zhang, Zhuming, Liu, Jin-Jun, Jiang, Nan, Zhang, Jing, Ross, Tina M, Chu, Xin-Jie, Bartkovitz, David, Podlaski, Frank, Janson, Cheryl, Tovar, Christian, Filipovic, Zoran M, Higgins, Brian, Glenn, Kelli, Packman, Kathryn, Vassilev, Lyubomir T, Graves, Bradford

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The Tuberculosis Drug Accelerator at year 10: what have we learned? von Aldridge, Bree B., Barros-Aguirre, David, Barry, Clifton E., Bates, Robert H., Berthel, Steven J., Boshoff, Helena I., Chibale, Kelly, Chu, Xin-Jie, Cooper, Christopher B., Dartois, Véronique, Duncan, Ken, Fotouhi, Nader, Gusovsky, Fabian, Hipskind, Philip A., Kempf, Dale J., Lelièvre, Joël, Lenaerts, Anne J., McNamara, Case W., Mizrahi, Valerie, Nathan, Carl, Olsen, David B., Parish, Tanya, Petrassi, H. Michael, Pym, Alexander, Rhee, Kyu Y., Robertson, Gregory T., Rock, Jeremy Michael, Rubin, Eric J., Russell, Betsy, Russell, David G., Sacchettini, James C., Schnappinger, Dirk, Schrimpf, Michael, Upton, Anna M., Warner, Peter, Wyatt, Paul Graham, Yuan, Ying

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Intensified micro-mixing effects on evolution of oxygen vacancies of CeO2-based catalysts for improved CO oxidation von Wang, Bao-Ju, Chu, Guang-Wen, Li, Yan-Bin, Duan, Xue-Zhi, Wang, Jie-Xin, Luo, Yong

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Discovery of Potent and Orally Active p53-MDM2 Inhibitors RO5353 and RO2468 for Potential Clinical Development von Zhang, Zhuming, Chu, Xin-Jie, Liu, Jin-Jun, Ding, Qingjie, Zhang, Jing, Bartkovitz, David, Jiang, Nan, Karnachi, Prabha, So, Sung-Sau, Tovar, Christian, Filipovic, Zoran M, Higgins, Brian, Glenn, Kelli, Packman, Kathryn, Vassilev, Lyubomir, Graves, Bradford

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Experimental Study on Emergency Reclaiming of Offshore Underwater Leakage Oil von Gao, Hui, Xu, Song Sen, Chu, Xin Jie

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Discovery of HPG1860, a Structurally Novel Nonbile Acid FXR Agonist Currently in Clinical Development for the Treatment of Nonalcoholic Steatohepatitis von Mo, Cheng, Xu, Xiaoqing, Zhang, Pan, Peng, Yihong, Zhao, Xinpeng, Chen, Shijia, Guo, Fang, Xiong, Yating, Chu, Xin-Jie, Xu, Xiaodong

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Identification of novel, potent and selective inhibitors of Polo-like kinase 1 von Chen, Shaoqing, Bartkovitz, David, Cai, Jianping, Chen, Yi, Chen, Zhi, Chu, Xin-Jie, Le, Kang, Le, Nam T., Luk, Kin-Chun, Mischke, Steve, Naderi-Oboodi, Goli, Boylan, John F., Nevins, Tom, Qing, Weiguo, Chen, Yingsi, Wovkulich, Peter M.

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In vitro and in vivo activity of R547: a potent and selective cyclin-dependent kinase inhibitor currently in phase I clinical trials von DePinto, Wanda, Chu, Xin-Jie, Yin, Xuefeng, Smith, Melissa, Packman, Kathryn, Goelzer, Petra, Lovey, Allen, Chen, Yingsi, Qian, Hong, Hamid, Rachid, Xiang, Qing, Tovar, Christian, Blain, Roger, Nevins, Tom, Higgins, Brian, Luistro, Leopoldo, Kolinsky, Kenneth, Felix, Bernardo, Hussain, Sazzad, Heimbrook, David

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Total Synthesis of Vancomycin-Part 1: Design and Development of Methodology von Nicolaou, K. C., Li, Hui, Boddy, Christopher N. C., Ramanjulu, Joshi M., Yue, Tai-Yuen, Natarajan, Swaminathan, Chu, Xin-Jie, Bräse, Stefan, Rübsam, Frank

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Discovery of potent and selective spiroindolinone MDM2 inhibitor, RO8994, for cancer therapy von Zhang, Zhuming, Ding, Qingjie, Liu, Jin-Jun, Zhang, Jing, Jiang, Nan, Chu, Xin-Jie, Bartkovitz, David, Luk, Kin-Chun, Janson, Cheryl, Tovar, Christian, Filipovic, Zoran M., Higgins, Brian, Glenn, Kelli, Packman, Kathryn, Vassilev, Lyubomir T., Graves, Bradford

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Total synthesis and structural revision of chromomoric acid D-I methyl ester von Liu, Zhi-Yu, Chu, Xin-Jie

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Total Synthesis of Brevetoxin A: Part 1: First Generation Strategy and Construction of BCD Ring System von Nicolaou, K. C., Bunnage, Mark E., McGarry, Daniel G., Shi, Shuhao, Somers, Patricia K., Wallace, Paul A., Chu, Xin-Jie, Agrios, Konstantinos A., Gunzner, Janet L., Yang, Zhen

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Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV‑1 Protease Inhibitors von Bungard, Christopher J, Williams, Peter D, Schulz, Jurgen, Wiscount, Catherine M, Holloway, M. Katharine, Loughran, H. Marie, Manikowski, Jesse J, Su, Hua-Poo, Bennett, David J, Chang, Lehua, Chu, Xin-Jie, Crespo, Alejandro, Dwyer, Michael P, Keertikar, Kartik, Morriello, Gregori J, Stamford, Andrew W, Waddell, Sherman T, Zhong, Bin, Hu, Bin, Ji, Tao, Diamond, Tracy L, Bahnck-Teets, Carolyn, Carroll, Steven S, Fay, John F, Min, Xu, Morris, William, Ballard, Jeanine E, Miller, Michael D, McCauley, John A

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A novel domino reaction for the preparation of substituted non-racemic β-proline derivatives von Gilbert, Eric J., Brunskill, Andrew, Cai, Jiaqiang, Cai, Yaxian, Chu, Xin-Jie, Dai, Xing, Hao, Jinsong, Kuethe, Jeffrey T., Lai, Zhong, Liu, Hong, Mu, Cuizhi, Qi, Yan, Scott, Jack D., Taoka, Brandon, Truong, Quang, Walsh, Shawn P., Wu, Wen-Lian, Cumming, Jared N.

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Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), A Potent and Selective Cyclin-Dependent Kinase Inhibit... von Chu, Xin-Jie, DePinto, Wanda, Bartkovitz, David, So, Sung-Sau, Vu, Binh T, Packman, Kathryn, Lukacs, Christine, Ding, Qingjie, Jiang, Nan, Wang, Ka, Goelzer, Petra, Yin, Xuefeng, Smith, Melissa A, Higgins, Brian X, Chen, Yingsi, Xiang, Qing, Moliterni, John, Kaplan, Gerald, Graves, Bradford, Lovey, Allen, Fotouhi, Nader

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On 3-D Modeling CAD System of Production Platforms von Chu, Xin Jie

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A predictive pharmacophore model of human melanocortin-4 receptor as derived from the solution structures of cyclic peptides von Sun, Hongmao, Greeley, David N., Chu, Xin-Jie, Cheung, Adrian, Danho, Waleed, Swistok, Joseph, Wang, Yao, Zhao, Chunlin, Chen, Li, Fry, David C.

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Discovery of 1-amino-4-phenylcyclohexane-1-carboxylic acid and its influence on agonist selectivity between human melanocortin-4 and -1 receptors in linear pentapeptides von Chu, Xin-Jie, Bartkovitz, David, Danho, Waleed, Swistok, Joseph, Cheung, Adrian Wai-Hing, Kurylko, Grazyna, Rowan, Karen, Yeon, Mitch, Franco, Lucia, Qi, Lida, Chen, Li, Yagaloff, Keith

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Study on the Stability and Structural Optimization of Self-Elevating Platform Pile Foundation von Chu, Xin Jie

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