Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2 von Xie, Yuanchao, Yin, Wanchao, Zhang, Yumin, Shang, Weijuan, Wang, Zhen, Luan, Xiaodong, Tian, Guanghui, Aisa, Haji A., Xu, Yechun, Xiao, Gengfu, Li, Jia, Jiang, Hualiang, Zhang, Shuyang, Zhang, Leike, Xu, H. Eric, Shen, Jingshan

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The complete synthesis of favipiravir from 2-aminopyrazine von Guo, Qi, Xu, Mingshuo, Guo, Shuang, Zhu, Fuqiang, Xie, Yuanchao, Shen, Jingshan

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Oral remdesivir derivative VV116 is a potent inhibitor of respiratory syncytial virus with efficacy in mouse model von Zhang, Ruxue, Zhang, Yumin, Zheng, Wei, Shang, Weijuan, Wu, Yan, Li, Ning, Xiong, Jun, Jiang, Hualiang, Shen, Jingshan, Xiao, Gengfu, Xie, Yuanchao, Zhang, Leike

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Significant Inhibition of Porcine Epidemic Diarrhea Virus In Vitro by Remdesivir, Its Parent Nucleoside and β-d-N4-hydroxycytidine von Xie, Yuanchao, Guo, Xiaozhen, Hu, Tianwen, Wei, Daibao, Ma, Xiuli, Wu, Jiaqiang, Huang, Bing, Shen, Jingshan

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Design, synthesis and biological activity of thiazolidine-4-carboxylic acid derivatives as novel influenza neuraminidase inhibitors von Liu, Yu, Jing, Fanbo, Xu, Yingying, Xie, Yuanchao, Shi, Fangyuan, Fang, Hao, Li, Minyong, Xu, Wenfang

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Combination of miR159 Mimics and Irinotecan Utilizing Lipid Nanoparticles for Enhanced Treatment of Colorectal Cancer von Yang, Rulei, Liu, Yiran, Yang, Ning, Zhang, Tian, Hou, Jiazhen, He, Zongyan, Wang, Yutong, Sun, Xujie, Shen, Jingshan, Jiang, Hualiang, Xie, Yuanchao, Lang, Tianqun

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Synthesis and crystal structure of 6-fluoro-3-hydroxypyrazine-2-carboxamide von Shi, Fangyuan, Li, Zongtao, Kong, Lingjin, Xie, Yuanchao, Zhang, Tao, Xu, Wenfang

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A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir von Zhang, Yumin, Sun, Yuan, Xie, Yuanchao, Shang, Weijuan, Wang, Zhen, Jiang, Hualiang, Shen, Jingshan, Xiao, Gengfu, Zhang, Leike

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Development of patch and spray formulations for enhancing topical delivery of sinomenine hydrochloride von Li, Xinru, Li, Xiaoyan, Zhou, Yanxia, Liu, Yan, Guo, Ming, Zhu, Qingfen, Xie, Yuanchao, Fan, Zhiyun

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An Active Power Decoupling Topology for Three-phase Four-leg Inverters with Unbalanced Load von Xie, Yuanchao, Wang, Fusheng, Liu, Heng

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Research on Common Mode Voltage Suppression Algorithm Based on Three Levels von Liu, Heng, Wang, Fusheng, Xie, Yuanchao

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Synthesis and anti-SARS-CoV-2 activity of deuterated GS-441524 analogs von Zheng, Wei, Hu, Tianwen, Zhang, Yumin, Wei, Daibao, Xie, Yuanchao, Shen, Jingshan

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Potency and pharmacokinetics of GS-441524 derivatives against SARS-CoV-2 von Wei, Daibao, Hu, Tianwen, Zhang, Yumin, Zheng, Wei, Xue, Haitao, Shen, Jingshan, Xie, Yuanchao, Aisa, Haji A.

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Challenges and stepwise fit-for-purpose optimization for bioanalyses of remdesivir metabolites nucleotide monophosphate and triphosphate in mouse tissues using LC–MS/MS von Hu, Wenjuan, Chang, Lu, Ke, Changqiang, Xie, Yuanchao, Shen, Jingshan, Tan, Bo, Liu, Jia

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Synthesis and evaluation of NHC derivatives and 4′-fluorouridine prodrugs von Xiang, Li, Hu, Tianwen, Xue, Haitao, Pan, Wenfang, Xie, Yuanchao, Shen, Jingshan

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Synthesis of CBD and Its Derivatives Bearing Various C4′-Side Chains with a Late-Stage Diversification Method von Gong, Xudong, Sun, Changliang, Abame, Melkamu Alemu, Shi, Wenqiang, Xie, Yuanchao, Xu, Wanbin, Zhu, Fuqiang, Zhang, Yan, Shen, Jingshan, Aisa, Haji A

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Weinreb Amide Approach to the Practical Synthesis of a Key Remdesivir Intermediate von Xie, Yuanchao, Hu, Tianwen, Zhang, Yan, Wei, Daibao, Zheng, Wei, Zhu, Fuqiang, Tian, Guanghui, Aisa, Haji A, Shen, Jingshan

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Discovery of N‑Substituted Oseltamivir Derivatives as Potent and Selective Inhibitors of H5N1 Influenza Neuraminidase von Xie, Yuanchao, Xu, Dongqing, Huang, Bing, Ma, Xiuli, Qi, Wenbao, Shi, Fangyuan, Liu, Xinyong, Zhang, Yingjie, Xu, Wenfang

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“One-Pot” Synthesis of Molnupiravir from Cytidine von Hu, Tianwen, Xie, Yuanchao, Zhu, Fuqiang, Gong, Xudong, Liu, Yin, Xue, Haitao, Aisa, Haji A, Shen, Jingshan

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Automated design and optimization of multitarget schizophrenia drug candidates by deep learning von Tan, Xiaoqin, Jiang, Xiangrui, He, Yang, Zhong, Feisheng, Li, Xutong, Xiong, Zhaoping, Li, Zhaojun, Liu, Xiaohong, Cui, Chen, Zhao, Qingjie, Xie, Yuanchao, Yang, Feipu, Wu, Chunhui, Shen, Jingshan, Zheng, Mingyue, Wang, Zhen, Jiang, Hualiang

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