Proline Isomer-Specific Antibodies Reveal the Early Pathogenic Tau Conformation in Alzheimer's Disease von Nakamura, Kazuhiro, Greenwood, Alex, Binder, Lester, Bigio, Eileen H., Denial, Sarah, Nicholson, Linda, Zhou, Xiao Zhen, Lu, Kun Ping

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A novel controlled release formulation of the Pin1 inhibitor ATRA to improve liver cancer therapy by simultaneously blocking multiple cancer pathways von Yang, Dayun, Luo, Wensong, Wang, Jichuang, Zheng, Min, Liao, Xin-Hua, Zhang, Nan, Lu, Wenxian, Wang, Long, Chen, Ai-Zheng, Wu, Wen-Guo, Liu, Hekun, Wang, Shi-Bin, Zhou, Xiao Zhen, Lu, Kun Ping

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Death-Associated Protein Kinase 1 Phosphorylates Pin1 and Inhibits Its Prolyl Isomerase Activity and Cellular Function von Lee, Tae Ho, Chen, Chun-Hau, Suizu, Futoshi, Huang, Pengyu, Schiene-Fischer, Cordelia, Daum, Sebastian, Zhang, Yan Jessie, Goate, Alison, Chen, Ruey-Hwa, Zhou, Xiao Zhen, Lu, Kun Ping

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ATR Plays a Direct Antiapoptotic Role at Mitochondria, which Is Regulated by Prolyl Isomerase Pin1 von Hilton, Benjamin A., Li, Zhengke, Musich, Phillip R., Wang, Hui, Cartwright, Brian M., Serrano, Moises, Zhou, Xiao Zhen, Lu, Kun Ping, Zou, Yue

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The Rab2A GTPase Promotes Breast Cancer Stem Cells and Tumorigenesis via Erk Signaling Activation von Luo, Man-Li, Gong, Chang, Chen, Chun-Hau, Hu, Hai, Huang, Pengyu, Zheng, Min, Yao, Yandan, Wei, Shuo, Wulf, Gerburg, Lieberman, Judy, Zhou, Xiao Zhen, Song, Erwei, Lu, Kun Ping

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The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target von Zhou, Xiao Zhen, Lu, Kun Ping

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MicroRNA-140-5p inhibits hepatocellular carcinoma by directly targeting the unique isomerase Pin1 to block multiple cancer-driving pathways von Yan, Xingxue, Zhu, Zhendong, Xu, Shenmin, Yang, Li-nan, Liao, Xin-Hua, Zheng, Min, Yang, Dayun, Wang, Jichuang, Chen, Dongmei, Wang, Long, Liu, Xiaolong, Liu, Jingfeng, Chen, Ruey-Hwa, Zhou, Xiao Zhen, Lu, Kun Ping, Liu, Hekun

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The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-β production von Xia, Weiming, Lu, Pei-Jung, Li, Shi-Hua, Finn, Greg, Sun, Anyang, Nicholson, Linda K, Pastorino, Lucia, Zhou, Xiao Zhen, Balastik, Martin, Lim, Jormay, Lu, Kun Ping, Wulf, Gerburg, Li, Xiaojiang

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Pin1‐Targeted Therapy for Systemic Lupus Erythematosus von Wei, Shuo, Yoshida, Nobuya, Finn, Greg, Kozono, Shingo, Nechama, Morris, Kyttaris, Vasileios C., Zhen Zhou, Xiao, Tsokos, George C., Ping Lu, Kun

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Targeting PIN1 exerts potent antitumor activity in pancreatic ductal carcinoma via inhibiting tumor metastasis von Chen, Linying, Xu, Xiao, Wen, Xinxin, Xu, Shenmin, Wang, Long, Lu, Wenxian, Jiang, Mingting, Huang, Jing, Yang, Dayun, Wang, Jichuang, Zheng, Min, Zhou, Xiao Zhen, Lu, Kun Ping, Liu, Hekun

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Inhibition of the prolyl isomerase Pin1 enhances the ability of sorafenib to induce cell death and inhibit tumor growth in hepatocellular carcinoma von Zheng, Min, Xu, Huijuan, Liao, Xin-Hua, Chen, Champ Peng, Zhang, Arina Li, Lu, Wenxian, Wang, Long, Yang, Dayun, Wang, Jichuang, Liu, Hekun, Zhou, Xiao Zhen, Lu, Kun Ping

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"Tau immunotherapy: Hopes and hindrances" von Shahpasand, Koorosh, Sepehri Shamloo, Alireza, Nabavi, Seyed Massood, Ping Lu, Kun, Zhen Zhou, Xiao

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Prolyl Isomerase Pin1 Regulates Axon Guidance by Stabilizing CRMP2A Selectively in Distal Axons von Balastik, Martin, Zhou, Xiao Zhen, Alberich-Jorda, Meritxell, Weissova, Romana, Žiak, Jakub, Pazyra-Murphy, Maria F., Cosker, Katharina E., Machonova, Olga, Kozmikova, Iryna, Chen, Chun-Hau, Pastorino, Lucia, Asara, John M., Cole, Adam, Sutherland, Calum, Segal, Rosalind A., Lu, Kun Ping

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Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins von Liou, Yih-Cherng, Zhou, Xiao Zhen, Lu, Kun Ping

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Death-Associated Protein Kinase 1 Phosphorylation in Neuronal Cell Death and Neurodegenerative Disease von Kim, Nami, Chen, Dongmei, Zhou, Xiao Zhen, Lee, Tae Ho

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Inversion-based data-driven time-space domain random noise attenuation method von Zhao, Yu-Min, Li, Guo-Fa, Wang, Wei, Zhou, Zhen-Xiao, Tang, Bo-Wen, Zhang, Wen-Bo

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Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy von Kondo, Asami, Shahpasand, Koorosh, Mannix, Rebekah, Qiu, Jianhua, Moncaster, Juliet, Chen, Chun-Hau, Yao, Yandan, Lin, Yu-Min, Driver, Jane A., Sun, Yan, Wei, Shuo, Luo, Man-Li, Albayram, Onder, Huang, Pengyu, Rotenberg, Alexander, Ryo, Akihide, Goldstein, Lee E., Pascual-Leone, Alvaro, McKee, Ann C., Meehan, William, Zhou, Xiao Zhen, Lu, Kun Ping

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Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells von Kozono, Shingo, Lin, Yu-Min, Seo, Hyuk-Soo, Pinch, Benika, Lian, Xiaolan, Qiu, Chenxi, Herbert, Megan K., Chen, Chun-Hau, Tan, Li, Gao, Ziang Jeff, Massefski, Walter, Doctor, Zainab M., Jackson, Brian P., Chen, Yuanzhong, Dhe-Paganon, Sirano, Lu, Kun Ping, Zhou, Xiao Zhen

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Targeting EGFR of triple-negative breast cancer enhances the therapeutic efficacy of paclitaxel- and cetuximab-conjugated nanodiamond nanocomposite von Liao, Wei-Siang, Ho, Yu, Lin, Yu-Wei, Naveen Raj, Emmanuel, Liu, Kuang-Kai, Chen, Chinpiao, Zhou, Xiao-Zhen, Lu, Kun-Ping, Chao, Jui-I

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Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer's disease von Driver, Jane A., Zhou, Xiao Zhen, Lu, Kun Ping

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