Structure basis for RNA-guided DNA degradation by Cascade and Cas3 von Xiao, Yibei, Luo, Min, Dolan, Adam E, Liao, Maofu, Ke, Ailong

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Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System von Xiao, Yibei, Luo, Min, Hayes, Robert P., Kim, Jonathan, Ng, Sherwin, Ding, Fang, Liao, Maofu, Ke, Ailong

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Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas von Dolan, Adam E., Hou, Zhonggang, Xiao, Yibei, Gramelspacher, Max J., Heo, Jaewon, Howden, Sara E., Freddolino, Peter L., Ke, Ailong, Zhang, Yan

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Structural basis for promiscuous PAM recognition in type I–E Cascade from E. coli von Hayes, Robert P., Xiao, Yibei, Ding, Fran, van Erp, Paul B. G., Rajashankar, Kanagalaghatta, Bailey, Scott, Wiedenheft, Blake, Ke, Ailong

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Targeting dual-specificity tyrosine phosphorylation-regulated kinase 2 with a highly selective inhibitor for the treatment of prostate cancer von Yuan, Kai, Li, Zhaoxing, Kuang, Wenbin, Wang, Xiao, Ji, Minghui, Chen, Weijiao, Ding, Jiayu, Li, Jiaxing, Min, Wenjian, Sun, Chengliang, Ye, Xiuquan, Lu, Meiling, Wang, Liping, Ge, Haixia, Jiang, Yuzhang, Hao, Haiping, Xiao, Yibei, Yang, Peng

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Structure and genome editing of type I-B CRISPR-Cas von Lu, Meiling, Yu, Chenlin, Zhang, Yuwen, Ju, Wenjun, Ye, Zhi, Hua, Chenyang, Mao, Jinze, Hu, Chunyi, Yang, Zhenhuang, Xiao, Yibei

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Real-time observation of CRISPR spacer acquisition by Cas1–Cas2 integrase von Budhathoki, Jagat B., Xiao, Yibei, Schuler, Gabriel, Hu, Chunyi, Cheng, Alexander, Ding, Fran, Ke, Ailong

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Mechanistic insights into lanthipeptide modification by a distinct subclass of LanKC enzyme that forms dimers von Li, Yifan, Shao, Kai, Li, Zhaoxing, Zhu, Kongfu, Gan, Bee Koon, Shi, Jian, Xiao, Yibei, Luo, Min

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Assembly and Translocation of a CRISPR-Cas Primed Acquisition Complex von Dillard, Kaylee E., Brown, Maxwell W., Johnson, Nicole V., Xiao, Yibei, Dolan, Adam, Hernandez, Erik, Dahlhauser, Samuel D., Kim, Yoori, Myler, Logan R., Anslyn, Eric V., Ke, Ailong, Finkelstein, Ilya J.

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Novel Inhibitors of 2'- O -Methyltransferase of the SARS-CoV-2 Coronavirus von Sulimov, Alexey, Kutov, Danil, Ilin, Ivan, Xiao, Yibei, Jiang, Sheng, Sulimov, Vladimir

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Massively Parallel Biophysical Analysis of CRISPR-Cas Complexes on Next Generation Sequencing Chips von Jung, Cheulhee, Hawkins, John A., Jones, Stephen K., Xiao, Yibei, Rybarski, James R., Dillard, Kaylee E., Hussmann, Jeffrey, Saifuddin, Fatema A., Savran, Cagri A., Ellington, Andrew D., Ke, Ailong, Press, William H., Finkelstein, Ilya J.

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Precise Gene Knock‐In Tools with Minimized Risk of DSBs: A Trend for Gene Manipulation von Liu, Yongfeng, Kong, Jianping, Liu, Gongyu, Li, Zhaoxing, Xiao, Yibei

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Mechanistic insights into transposon cleavage and integration by TnsB of ShCAST system von Zeng, Ting, Yin, Jie, Liu, Ziwen, Li, Zhaoxing, Zhang, Yu, Lv, Yang, Lu, Mei-Ling, Luo, Min, Chen, Meirong, Xiao, Yibei

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Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation von Ge, Zehe, Xu, Miao, Ge, Yuqian, Huang, Guang, Chen, Dongyin, Ye, Xiuquan, Xiao, Yibei, Zhu, Hongyu, Yin, Rong, Shen, Hua, Ma, Gaoxiang, Qi, Lianwen, Wei, Guining, Li, Dongmei, Wei, Shaofeng, Zhu, Meng, Ma, Hongxia, Shi, Zhumei, Wang, Xiuxing, Ge, Xin, Qian, Xu

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Nonstructural Proteins 7 and 8 of Feline Coronavirus Form a 2:1 Heterotrimer That Exhibits Primer-Independent RNA Polymerase Activity von YIBEI XIAO, QINGJUN MA, RESTLE, Tobias, WEIFENG SHANG, SVERGUN, Dmitri I, PONNUSAMY, Rajesh, SCZAKIEL, Georg, HILGENFELDA, Rolf

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AHSA1 is a promising therapeutic target for cellular proliferation and proteasome inhibitor resistance in multiple myeloma von Gu, Chunyan, Wang, Yajun, Zhang, Lulin, Qiao, Li, Sun, Shanliang, Shao, Miaomiao, Tang, Xiaozhu, Ding, Pinggang, Tang, Chao, Cao, Yuhao, Zhou, Yanyan, Guo, Mengjie, Wei, Rongfang, Li, Nianguang, Xiao, Yibei, Duan, Jinao, Yang, Ye

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Novel phthalimides regulating PD-1/PD-L1 interaction as potential immunotherapy agents von Sun, Chengliang, Cheng, Yao, Liu, Xiaojia, Wang, Gefei, Min, Wenjian, Wang, Xiao, Yuan, Kai, Hou, Yi, Li, Jiaxing, Zhang, Haolin, Dong, Haojie, Wang, Liping, Lou, Chenguang, Sun, Yanze, Yu, Xinmiao, Deng, Hongbin, Xiao, Yibei, Yang, Peng

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Two types of coumarins-specific enzymes complete the last missing steps in pyran- and furanocoumarins biosynthesis von Zhao, Yucheng, He, Yuedong, Han, Liangliang, Zhang, Libo, Xia, Yuanzheng, Yin, Fucheng, Wang, Xiaobing, Zhao, Deqing, Xu, Sheng, Qiao, Fei, Xiao, Yibei, Kong, Lingyi

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Correction: AHSA1 is a promising therapeutic target for cellular proliferation and proteasome inhibitor resistance in multiple myeloma von Gu, Chunyan, Wang, Yajun, Zhang, Lulin, Qiao, Li, Sun, Shanliang, Shao, Miaomiao, Tang, Xiaozhu, Ding, Pinggang, Tang, Chao, Cao, Yuhao, Zhou, Yanyan, Guo, Mengjie, Wei, Rongfang, Li, Nianguang, Xiao, Yibei, Duan, Jinao, Yang, Ye

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Repurposing Type I-A CRISPR-Cas3 for a robust diagnosis of human papillomavirus (HPV) von Hu, Tao, Ji, Quanquan, Ke, Xinxin, Zhou, Hufeng, Zhang, Senfeng, Ma, Shengsheng, Yu, Chenlin, Ju, Wenjun, Lu, Meiling, Lin, Yu, Ou, Yangjing, Zhou, Yingsi, Xiao, Yibei, Xu, Chunlong, Hu, Chunyi

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