Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes von Camunas-Soler, Joan, Dai, Xiao-Qing, Hang, Yan, Bautista, Austin, Lyon, James, Suzuki, Kunimasa, Kim, Seung K., Quake, Stephen R., MacDonald, Patrick E.

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Cryopreservation and post-thaw characterization of dissociated human islet cells von Marquez-Curtis, Leah A, Dai, Xiao-Qing, Hang, Yan, Lam, Jonathan Y, Lyon, James, Manning Fox, Jocelyn E, McGann, Locksley E, MacDonald, Patrick E, Kim, Seung K, Elliott, Janet A W

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Study on the effect of 1.4-butynediol on the performance of electroplated diamond wire saw von Dai, Xiao-Nan, Zhou, Xue, Dai, Xiao-Qing, Sun, Chang-Hong, Sun, Wei-Yun, Bai, Ling, Li, Zheng-Xin

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Nano-porous carbon wrapped SiC nanowires with tunable dielectric properties for electromagnetic applications von Duan, Li-qun, Xu, Chang, Dai, Xiao-qing, Xiong, Zi-ming, Zhang, Bo, Zhang, Zhong-wei, Cui, Chuan-an, Xie, A-ming, Wu, Fan

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Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance von Skovsø, Søs, Panzhinskiy, Evgeniy, Kolic, Jelena, Cen, Haoning Howard, Dionne, Derek A., Dai, Xiao-Qing, Sharma, Rohit B., Elghazi, Lynda, Ellis, Cara E., Faulkner, Katharine, Marcil, Stephanie A. M., Overby, Peter, Noursadeghi, Nilou, Hutchinson, Daria, Hu, Xiaoke, Li, Hong, Modi, Honey, Wildi, Jennifer S., Botezelli, J. Diego, Noh, Hye Lim, Suk, Sujin, Gablaski, Brian, Bautista, Austin, Kim, Ryekjang, Cras-Méneur, Corentin, Flibotte, Stephane, Sinha, Sunita, Luciani, Dan S., Nislow, Corey, Rideout, Elizabeth J., Cytrynbaum, Eric N., Kim, Jason K., Bernal-Mizrachi, Ernesto, Alonso, Laura C., MacDonald, Patrick E., Johnson, James D.

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A role and mechanism for redox sensing by SENP1 in β-cell responses to high fat feeding von Lin, Haopeng, Suzuki, Kunimasa, Smith, Nancy, Li, Xi, Nalbach, Lisa, Fuentes, Sonia, Spigelman, Aliya F., Dai, Xiao-Qing, Bautista, Austin, Ferdaoussi, Mourad, Aggarwal, Saloni, Pepper, Andrew R., Roma, Leticia P., Ampofo, Emmanuel, Li, Wen-hong, MacDonald, Patrick E.

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Metabolomics applied to islet nutrient sensing mechanisms von Jensen, Mette V., Gooding, Jessica R., Ferdaoussi, Mourad, Dai, Xiao‐Qing, Peterson, Brett S., MacDonald, Patrick E., Newgard, Christopher B.

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SUMOylation Regulates Insulin Exocytosis Downstream of Secretory Granule Docking in Rodents and Humans von DAI, Xiao-Qing, PLUMMER, Greg, CASIMIR, Marina, YOUHOU KANG, HAJMRLE, Catherine, GAISANO, Herbert Y, MANNING FOX, Jocelyn E, MACDONALD, Patrick E

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Islet Cholesterol Accumulation Due to Loss of ABCA1 Leads to Impaired Exocytosis of Insulin Granules von KRUIT, Janine K, WIJESEKARA, Nadeeja, JOHNSON, James D, LIGHT, Peter E, MARSH, Brad J, MACDONALD, Patrick E, BRUCE VERCHERE, C, HAYDEN, Michael R, MANNING FOX, Jocelyn E, DAI, Xiao-Qing, BRUNHAM, Liam R, SEARLE, Gavin J, MORGAN, Garry P, COSTIN, Adam J, RENMEI TANG, BHATTACHARJEE, Alpana

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SUMO1 enhances cAMP‐dependent exocytosis and glucagon secretion from pancreatic α‐cells von Dai, Xiao‐Qing, Spigelman, Aliya F., Khan, Shara, Braun, Matthias, Manning Fox, Jocelyn E., MacDonald, Patrick E.

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Combinatorial transcription factor profiles predict mature and functional human islet α and β cells von Shrestha, Shristi, Saunders, Diane C, Walker, John T, Camunas-Soler, Joan, Dai, Xiao-Qing, Haliyur, Rachana, Aramandla, Radhika, Poffenberger, Greg, Prasad, Nripesh, Bottino, Rita, Stein, Roland, Cartailler, Jean-Philippe, Parker, Stephen Cj, MacDonald, Patrick E, Levy, Shawn E, Powers, Alvin C, Brissova, Marcela

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Structural interaction and functional regulation of polycystin-2 by filamin von Wang, Qian, Dai, Xiao-Qing, Li, Qiang, Wang, Zuocheng, Cantero, María del Rocío, Li, Shu, Shen, Ji, Tu, Jian-Cheng, Cantiello, Horacio, Chen, Xing-Zhen

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Kinesin-2 mediates physical and functional interactions between polycystin-2 and fibrocystin von Wu, Yuliang, Dai, Xiao-Qing, Li, Qiang, Chen, Carl X., Mai, Weiyi, Hussain, Zahir, Long, Wentong, Montalbetti, Nicolás, Li, Guochun, Glynne, Richard, Wang, Shaohua, Cantiello, Horacio F., Wu, Guanqing, Chen, Xing-Zhen

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Urea impairs β cell glycolysis and insulin secretion in chronic kidney disease von Koppe, Laetitia, Nyam, Elsa, Vivot, Kevin, Manning Fox, Jocelyn E, Dai, Xiao-Qing, Nguyen, Bich N, Trudel, Dominique, Attané, Camille, Moullé, Valentine S, MacDonald, Patrick E, Ghislain, Julien, Poitout, Vincent

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Inhibition of TRPP3 Channel by Amiloride and Analogs von Dai, Xiao-Qing, Ramji, Alkarim, Liu, Yan, Li, Qiang, Karpinski, Edward, Chen, Xing-Zhen

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Alpha-actinin associates with polycystin-2 and regulates its channel activity von Li, Qiang, Montalbetti, Nicolás, Shen, Patrick Y., Dai, Xiao-Qing, Cheeseman, Christopher I., Karpinski, Edward, Wu, Guanqing, Cantiello, Horacio F., Chen, Xing-Zhen

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Protocatechuic acid inhibits hepatitis B virus replication by activating ERK1/2 pathway and down-regulating HNF4α and HNF1α in vitro von Dai, Xiao-Qing, Cai, Wen-Tao, Wu, Xiao, Chen, Yong, Han, Feng-Mei

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Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes von Wang, Gaowei, Chiou, Joshua, Zeng, Chun, Miller, Michael, Matta, Ileana, Han, Jee Yun, Kadakia, Nikita, Okino, Mei-Lin, Beebe, Elisha, Mallick, Medhavi, Camunas-Soler, Joan, dos Santos, Theodore, Dai, Xiao-Qing, Ellis, Cara, Hang, Yan, Kim, Seung K., MacDonald, Patrick E., Kandeel, Fouad R., Preissl, Sebastian, Gaulton, Kyle J., Sander, Maike

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Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state von Dai, Xiao-Qing, Camunas-Soler, Joan, Briant, Linford J B, Dos Santos, Theodore, Spigelman, Aliya F, Walker, Emily M, Arrojo E Drigo, Rafael, Bautista, Austin, Jones, Robert C, Avrahami, Dana, Lyon, James, Nie, Aifang, Smith, Nancy, Zhang, Yongneng, Johnson, Janyne, Manning Fox, Jocelyn E, Michelakis, Evangelos D, Light, Peter E, Kaestner, Klaus H, Kim, Seung K, Rorsman, Patrik, Stein, Roland W, Quake, Stephen R, MacDonald, Patrick E

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Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion von Bozadjieva, Nadejda, Blandino-Rosano, Manuel, Chase, Jennifer, Dai, Xiao-Qing, Cummings, Kelsey, Gimeno, Jennifer, Dean, Danielle, Powers, Alvin C, Gittes, George K, Rüegg, Markus A, Hall, Michael N, MacDonald, Patrick E, Bernal-Mizrachi, Ernesto

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