Post-translational regulation of inflammasomes von Yang, Jie, Liu, Zhonghua, Xiao, Tsan Sam

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Human polymorphisms in GSDMD alter the inflammatory response von Rathkey, Joseph K., Xiao, Tsan S., Abbott, Derek W.

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The nucleic acid-sensing inflammasomes von Xiao, Tsan Sam

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Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity von Zhou, Chun, Chen, Xia, Planells-Cases, Rosa, Chu, Jiachen, Wang, Li, Cao, Limin, Li, Zhihong, López-Cayuqueo, Karen I., Xie, Yadong, Ye, Shiwei, Wang, Xiang, Ullrich, Florian, Ma, Shixin, Fang, Yiyuan, Zhang, Xiaoming, Qian, Zhikang, Liang, Xiaozheng, Cai, Shi-Qing, Jiang, Zhengfan, Zhou, Dongming, Leng, Qibin, Xiao, Tsan S., Lan, Ke, Yang, Jinbo, Li, Huabin, Peng, Chao, Qiu, Zhaozhu, Jentsch, Thomas J., Xiao, Hui

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Innate immunity and inflammation von Xiao, Tsan Sam

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Live-cell visualization of gasdermin D-driven pyroptotic cell death von Rathkey, Joseph K., Benson, Bryan L., Chirieleison, Steven M., Yang, Jie, Xiao, Tsan S., Dubyak, George R., Huang, Alex Y., Abbott, Derek W.

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IFI16 is an innate immune sensor for intracellular DNA von Unterholzner, Leonie, Keating, Sinead E, Baran, Marcin, Horan, Kristy A, Jensen, Søren B, Sharma, Shruti, Sirois, Cherilyn M, Jin, Tengchuan, Latz, Eicke, Xiao, T Sam, Fitzgerald, Katherine A, Paludan, Søren R, Bowie, Andrew G

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Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization von Liu, Zhonghua, Wang, Chuanping, Yang, Jie, Zhou, Bowen, Yang, Rui, Ramachandran, Rajesh, Abbott, Derek W., Xiao, Tsan Sam

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Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces von Zhu, Jianghai, Luo, Bing-Hao, Xiao, Tsan, Zhang, Chengzhong, Nishida, Noritaka, Springer, Timothy A.

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TH17 cells promote CNS inflammation by sensing danger signals via Mincle von Zhang, Quanri, Liu, Weiwei, Wang, Han, Zhou, Hao, Bulek, Katarzyna, Chen, Xing, Zhang, Cun-Jin, Zhao, Junjie, Zhang, Renliang, Liu, Caini, Kang, Zizhen, Bermel, Robert A., Dubyak, George, Abbott, Derek W., Xiao, Tsan Sam, Nagy, Laura E., Li, Xiaoxia

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Crystal structure of human NLRP12 PYD domain and implication in homotypic interaction von Jin, Tengchuan, Huang, Mo, Jiang, Jiansheng, Smith, Patrick, Xiao, Tsan Sam

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Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics von Xiao, Tsan, Takagi, Junichi, Coller, Barry S., Wang, Jia-Huai, Springer, Timothy A.

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Phosphorylation of the E3 ubiquitin protein ligase ITCH diminishes binding to its cognate E2 ubiquitin ligase von Perez, Jessica M., Chen, Yinghua, Xiao, Tsan S., Abbott, Derek W.

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The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release von Sette, Paola, Mu, Ruiling, Dussupt, Vincent, Jiang, Jiansheng, Snyder, Greg, Smith, Patrick, Xiao, Tsan Sam, Bouamr, Fadila

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Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA von Herzner, Anna-Maria, Hagmann, Cristina Amparo, Goldeck, Marion, Wolter, Steven, Kübler, Kirsten, Wittmann, Sabine, Gramberg, Thomas, Andreeva, Liudmila, Hopfner, Karl-Peter, Mertens, Christina, Zillinger, Thomas, Jin, Tengchuan, Xiao, Tsan Sam, Bartok, Eva, Coch, Christoph, Ackermann, Damian, Hornung, Veit, Ludwig, Janos, Barchet, Winfried, Hartmann, Gunther, Schlee, Martin

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Polyglutamine Tract Expansion Increases S-Nitrosylation of Huntingtin and Ataxin-1 von Ni, Chun-Lun, Seth, Divya, Fonseca, Fabio Vasconcelos, Wang, Liwen, Xiao, Tsan Sam, Gruber, Phillip, Sy, Man-Sun, Stamler, Jonathan S, Tartakoff, Alan M

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Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain von Mistry, Pragnesh, Laird, Michelle H. W., Schwarz, Ryan S., Greene, Shannon, Dyson, Tristan, Snyder, Greg A., Xiao, Tsan Sam, Chauhan, Jay, Fletcher, Steven, Toshchakov, Vladimir Y., MacKerell, Alexander D., Vogel, Stefanie N.

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SARS-CoV-2 ORF3a-Mediated NF-κB Activation Is Not Dependent on TRAF-Binding Sequence von Busscher, Brianna M, Befekadu, Henock B, Liu, Zhonghua, Xiao, Tsan Sam

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Design of an expression system to enhance MBP-mediated crystallization von Jin, Tengchuan, Chuenchor, Watchalee, Jiang, Jiansheng, Cheng, Jinbo, Li, Yajuan, Fang, Kang, Huang, Mo, Smith, Patrick, Xiao, Tsan Sam

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RAGE Enhances TLR Responses through Binding and Internalization of RNA von Bertheloot, Damien, Naumovski, Allison L, Langhoff, Pia, Horvath, Gabor L, Jin, Tengchuan, Xiao, Tsan Sam, Garbi, Natalio, Agrawal, Sudhir, Kolbeck, Roland, Latz, Eicke

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