Therapeutic Potential for Bone Morphogenetic Protein 4 in Human Malignant Glioma von Xi, Guifa, Best, Benjamin, Mania-Farnell, Barbara, James, Charles David, Tomita, Tadanori

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A Phenotypic Switch of Differentiated Glial Cells to Dedifferentiated Cells Is Regulated by Folate Receptor α von Monick, Sarah, Mohanty, Vineet, Khan, Mariam, Yerneni, Gowtham, Kumar, Raj, Cantu, Jorge, Ichi, Shunsuke, Xi, Guifa, Singh, Bal Ram, Tomita, Tadanori, Mayanil, Chandra Shekhar

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Convection-enhanced delivery of nanodiamond drug delivery platforms for intracranial tumor treatment von Xi, Guifa, MD, PhD, Robinson, Erik, PhD, Mania-Farnell, Barbara, PhD, Vanin, Elio Fausto, PhD, Shim, Kyu-Won, MD, PhD, Takao, Tsurubuchi, MD, PhD, Allender, Elise Victoria, MS, Mayanil, Chandra Shekhar, PhD, Soares, Marcelo Bento, PhD, Ho, Dean, PhD, Tomita, Tadanori, MD

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Pediatric Suprasellar Germ Cell Tumors: A Clinical and Radiographic Review of Solitary vs. Bifocal Tumors and Its Therapeutic Implications von Esfahani, Darian R., Alden, Tord, DiPatri, Arthur, Xi, Guifa, Goldman, Stewart, Tomita, Tadanori

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Targeting CD133 improves chemotherapeutic efficacy of recurrent pediatric pilocytic astrocytoma following prolonged chemotherapy von Xi, Guifa, Li, Yuping Derek, Grahovac, Gordan, Rajaram, Veena, Wadhwani, Nitin, Pundy, Tatiana, Mania-Farnell, Barbara, James, Charles David, Tomita, Tadanori

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Nuclear localization of folate receptor alpha: a new role as a transcription factor von Boshnjaku, Vanda, Shim, Kyu-Won, Tsurubuchi, Takao, Ichi, Shunsuke, Szany, Elise V., Xi, Guifa, Mania-Farnell, Barbara, McLone, David G., Tomita, Tadanori, Mayanil, C. Shekhar

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Bone Morphogenetic Protein 4 Targeting Glioma Stem-Like Cells for Malignant Glioma Treatment: Latest Advances and Implications for Clinical Application von Nayak, Sonali, Mahenthiran, Ashorne, Yang, Yongyong, McClendon, Mark, Mania-Farnell, Barbara, James, Charles David, Kessler, John A, Tomita, Tadanori, Cheng, Shi-Yuan, Stupp, Samuel I, Xi, Guifa

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Global Reduction of H3K4me3 Improves Chemotherapeutic Efficacy for Pediatric Ependymomas von Lewis, Rebecca, Li, Yuping D, Hoffman, Lindsey, Hashizume, Rintaro, Gravohac, Gordan, Rice, Gavin, Wadhwani, Nitin R, Jie, Chunfa, Pundy, Tatiana, Mania-Farnell, Barbara, Mayanil, Chandra S, Soares, Marcelo B, Lei, Ting, James, Charles D, Foreman, Nicolas K, Tomita, Tadanori, Xi, Guifa

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LRIG2 promotes glioblastoma progression by modulating innate antitumor immunity through macrophage infiltration and polarization von Hu, Jinyang, Dong, Feng, He, You, Xia, Xianyou, Cheng, Fangling, Chen, Sui, Hou, Xiaoshuang, Zhang, Po, Liu, Guohao, Li, Ying, Gao, Qian, Dong, Minhai, Li, Ting, Li, Wei, Xiao, Qungen, Li, Xiaopeng, Yu, Xingjiang, Xi, Guifa, Guo, Dongsheng, Wu, Xudong, Wang, Baofeng

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Onset of rosette formation during spontaneous neural differentiation of hESC and hiPSC colonies von Malchenko, Sergey, Xie, Jianping, de Fatima Bonaldo, Maria, Vanin, Elio F., Bhattacharyya, Bula J., Belmadani, Abdelhak, Xi, Guifa, Galat, Vasily, Goossens, William, Seftor, Richard E.B., Tomita, Tadanori, Crispino, John, Miller, Richard J., Bohn, Martha C., Hendrix, Mary J.C., Soares, Marcelo B.

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Histone modification as a drug resistance driver in brain tumors von Xi, Guifa, Mania-Farnell, Barbara, Lei, Ting, Tomita, Tadanori

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PATH-07. SIGNIFICANCE OF H3K4me3 IN PEDIATRIC HIGH-GRADE GLIOMAS von Lewis, Rebecca, Wadhwani, Nitin, Mania-Farnell, Barbara, Tomita, Tadanori, James, Charles, Xi, Guifa

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Advanced Pediatric Diffuse Pontine Glioma Murine Models Pave the Way towards Precision Medicine von Chen, Zirong, Peng, Peng, Zhang, Xiaolin, Mania-Farnell, Barbara, Xi, Guifa, Wan, Feng

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WDR82-Mediated H3K4me3 Is Associated with Tumor Proliferation and Therapeutic Efficacy in Pediatric High-Grade Gliomas von Wadhwani, Nitin, Nayak, Sonali, Wang, Yufen, Hashizume, Rintaro, Jie, Chunfa, Mania-Farnell, Barbara, James, Charles David, Xi, Guifa, Tomita, Tadanori

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Abstract 2871: Global reduction of H3K4me3 improves chemotherapeutic efficacy for pediatric ependymomas von Xi, Guifa, Wadhwani, Nitin, Hashizume, Rintaro, Mania-Farnell, Barbara, Soares, Marcelo Bento, James, Charles D., Tomita, Tadanori

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A neurodevelopmental epigenetic programme mediated by SMARCD3–DAB1–Reelin signalling is hijacked to promote medulloblastoma metastasis von Zou, Han, Poore, Bradley, Brown, Emily E., Qian, Jieqi, Xie, Bin, Asimakidou, Evridiki, Razskazovskiy, Vladislav, Ayrapetian, Deanna, Sharma, Vaibhav, Xia, Shunjin, Liu, Fei, Chen, Apeng, Guan, Yongchang, Li, Zhengwei, Wanggou, Siyi, Saulnier, Olivier, Ly, Michelle, Fellows-Mayle, Wendy, Xi, Guifa, Tomita, Tadanori, Resnick, Adam C., Mack, Stephen C., Raabe, Eric H., Eberhart, Charles G., Sun, Dandan, Stronach, Beth E., Agnihotri, Sameer, Kohanbash, Gary, Lu, Songjian, Herrup, Karl, Rich, Jeremy N., Gittes, George K., Broniscer, Alberto, Hu, Zhongliang, Li, Xuejun, Pollack, Ian F., Friedlander, Robert M., Hainer, Sarah J., Taylor, Michael D., Hu, Baoli

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Abstract 3175: Sulfated glycopeptide nanostructures activate and extend bone morphogenetic protein 4 ability to increase pediatric malignant glioma chemotherapeutic efficacy von Xi, Guifa, Best, Benjamin, Nayak, Sonali, McClendon, Mark, Mania-Farnell, Barbara, Kessler, John, James, Charles David, Stupp, Samuel, Tomita, Tadanori

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HGG-19. BONE MORPHOGENETIC PROTEIN 4 DIFFERENTIATES GLIOMA STEM CELLS TO INCREASES CHEMOSENSITIVITY VIA DECREASING H3K4me3 IN PEDIATRIC HIGH GRADE GLIOMAS von Nayak, Sonali, Best, Benamin, Hayes, Emily, Mania-Farnell, Barbara, Tomita, Tadanori, Xi, Guifa

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Abstract 2084: Reprogramming the epigenome as an effective treatment option for neurofibromatosis1 associated malignant peripheral nerve sheath tumors von Mayanil, Chandra S., Khan, Mariam M., Mohanty, Vineet, Kumar, Raj, Xi, Guifa, Ichi, Shunsuke, Singh, Bal Ram, Mania-Farnell, Barbara, Tomita, Tadanori

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NFM-10. TARGETING NuRD AND KAT7 FOR EPIGENOME MODIFICATION IN NEUROFIBROMATOSIS1 ASSOCIATED MALIGNANT PERIPHERAL NERVE SHEATH TUMORS von Mayanil, Chandra, Khan, Mariam, Mohanty, Vineet, Kumar, Raj, Xi, Guifa, Ichi, Shunsuke, Singh, Bal Ram, Mania-Farnell, Barbara, Tomita, Tadanori

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