Characterization of RNA driven structural changes in full length RIG-I leading to its agonism or antagonism von Sikorska, Justyna, Hou, Yan, Chiurazzi, Paul, Siu, Tony, Baltus, Gretchen A, Sheth, Payal, McLaren, David G, Truong, Quang, Parish, Craig A, Wyss, Daniel F

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Structural and biological characterization of pegylated recombinant interferon alpha-2b and its therapeutic implications von Wang, Yu-Sen, Youngster, Stephen, Grace, Michael, Bausch, James, Bordens, Ronald, Wyss, Daniel F.

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An orally available non-nucleotide STING agonist with antitumor activity von Pan, Bo-Sheng, Perera, Samanthi A, Piesvaux, Jennifer A, Presland, Jeremy P, Schroeder, Gottfried K, Cumming, Jared N, Trotter, B Wesley, Altman, Michael D, Buevich, Alexei V, Cash, Brandon, Cemerski, Saso, Chang, Wonsuk, Chen, Yiping, Dandliker, Peter J, Feng, Guo, Haidle, Andrew, Henderson, Timothy, Jewell, James, Kariv, Ilona, Knemeyer, Ian, Kopinja, Johnny, Lacey, Brian M, Laskey, Jason, Lesburg, Charles A, Liang, Rui, Long, Brian J, Lu, Min, Ma, Yanhong, Minnihan, Ellen C, O'Donnell, Greg, Otte, Ryan, Price, Laura, Rakhilina, Larissa, Sauvagnat, Berengere, Sharma, Sharad, Tyagarajan, Sriram, Woo, Hyun, Wyss, Daniel F, Xu, Serena, Bennett, David Jonathan, Addona, George H

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Recent developments in understanding RIG-I's activation and oligomerization von Sikorska, Justyna, Wyss, Daniel F

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Competition STD NMR for the detection of high-affinity ligands and NMR-based screening von Wang, Yu-Sen, Liu, Dingjiang, Wyss, Daniel F.

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Spatial Localization of Ligand Binding Sites from Electron Current Density Surfaces Calculated from NMR Chemical Shift Perturbations von McCoy, Mark A, Wyss, Daniel F

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Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer von Chang, Wonsuk, Altman, Michael D, Lesburg, Charles A, Perera, Samanthi A, Piesvaux, Jennifer A, Schroeder, Gottfried K, Wyss, Daniel F, Cemerski, Saso, Chen, Yiping, DiNunzio, Edward, Haidle, Andrew M, Ho, Thu, Kariv, Ilona, Knemeyer, Ian, Kopinja, Johnny E, Lacey, Brian M, Laskey, Jason, Lim, Jongwon, Long, Brian J, Ma, Yanhong, Maddess, Matthew L, Pan, Bo-Sheng, Presland, Jeremy P, Spooner, Edward, Steinhuebel, Dietrich, Truong, Quang, Zhang, Zhibo, Fu, Jianmin, Addona, George H, Northrup, Alan B, Parmee, Emma, Tata, James R, Bennett, David Jonathan, Cumming, Jared N, Siu, Tony, Trotter, B. Wesley

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Flexible Lid to the p53-Binding Domain of Human Mdm2: Implications for p53 Regulation von McCoy, Mark A., Gesell, Jennifer J., Senior, Mary M., Wyss, Daniel F.

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Identification of the Major Positional Isomer of Pegylated Interferon Alpha-2b von Wang, Yu-Sen, Youngster, Stephen, Bausch, James, Zhang, Rumin, McNemar, Charles, Wyss, Daniel F

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Structures of Protein−Protein Complexes Are Docked Using Only NMR Restraints from Residual Dipolar Coupling and Chemical Shift Perturbations von McCoy, Mark A, Wyss, Daniel F

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Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates von Mandal, Mihirbaran, Xiao, Li, Pan, Weidong, Scapin, Giovanna, Li, Guoqing, Tang, Haiqun, Yang, Shu-Wei, Pan, Jianping, Root, Yuriko, de Jesus, Reynalda Keh, Yang, Christine, Prosise, Winnie, Dayananth, Priya, Mirza, Asra, Therien, Alex G., Young, Katherine, Flattery, Amy, Garlisi, Charles, Zhang, Rumin, Chu, Donald, Sheth, Payal, Chu, Inhou, Wu, Jin, Markgraf, Carrie, Kim, Hai-Young, Painter, Ronald, Mayhood, Todd W., DiNunzio, Edward, Wyss, Daniel F., Buevich, Alexei V., Fischmann, Thierry, Pasternak, Alexander, Dong, Shuzhi, Hicks, Jacqueline D., Villafania, Artjohn, Liang, Lianzhu, Murgolo, Nicholas, Black, Todd, Hagmann, William K., Tata, Jim, Parmee, Emma R., Weber, Ann E., Su, Jing, Tang, Haifeng

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Sequence-Specific Assignments of Methyl Groups in High-Molecular Weight Proteins von Yang, Daiwen, Zheng, Yu, Liu, Dingjiang, Wyss, Daniel F

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Conformation and Function of the N-Linked Glycan in the Adhesion Domain of Human CD2 von Wyss, Daniel F., Choi, Johnathan S., Li, Jing, Knoppers, Maria H., Willis, Kevin J., Antonio R. N. Arulanandam, Smolyar, Alex, Reinherz, Ellis L., Wagner, Gerhard

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The structural role of sugars in glycoproteins von Wyss, Daniel F, Wagner, Gerhard

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Discovery of Cyclic Acylguanidines as Highly Potent and Selective β-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part IInhibitor Design and Validation von Zhu, Zhaoning, Sun, Zhong-Yue, Ye, Yuanzan, Voigt, Johannes, Strickland, Corey, Smith, Elizabeth M, Cumming, Jared, Wang, Lingyan, Wong, Jesse, Wang, Yu-Sen, Wyss, Daniel F, Chen, Xia, Kuvelkar, Reshma, Kennedy, Matthew E, Favreau, Leonard, Parker, Eric, McKittrick, Brian A, Stamford, Andrew, Czarniecki, Michael, Greenlee, William, Hunter, John C

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NMR Screening in Fragment-Based Drug Design: A Practical Guide von Kim, Hai-Young, Wyss, Daniel F.

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Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel μM Leads for the Development of nM... von Wang, Yu-Sen, Strickland, Corey, Voigt, Johannes H, Kennedy, Matthew E, Beyer, Brian M, Senior, Mary M, Smith, Elizabeth M, Nechuta, Terry L, Madison, Vincent S, Czarniecki, Michael, McKittrick, Brian A, Stamford, Andrew W, Parker, Eric M, Hunter, John C, Greenlee, William J, Wyss, Daniel F

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NMR Binding and Functional Assays for Detecting Inhibitors of S. aureus MnaA von Hou, Yan, Mayhood, Todd, Sheth, Payal, Tan, Christopher M., Labroli, Marc, Su, Jing, Wyss, Daniel F., Roemer, Terry, McCoy, Mark A.

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Effective Progression of Nuclear Magnetic Resonance-Detected Fragment Hits von Eaton, Hugh L., Wyss, Daniel F.

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Screening of Protein Kinases by ATP-STD NMR Spectroscopy von McCoy, Mark A., Senior, Mary M., Wyss, Daniel F.

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