3-Substituted GABA analogs with central nervous system activity: A review von Bryans, Justin S., Wustrow, David J.

Volltext

555 CB-5083, a first in class inhibitor of the AAA-ATPase p97/VCP, induces irresolvable ER stress that results in antitumor activity in solid and hematological tumor models von Yakes, F, Le Moigne, R, Wong, S, Anderson, D.J, Djakovic, S, Valle, E, Menon, M.K, Rice, J, Yao, B, Soriano, F, Wang, J, von Soly, S. Kiss, Chesi, M, Bergsagel, P.L, Zhou, H.J, Rolfe, M, Wustrow, D

Volltext

Isoindolinone enantiomers having affinity for the dopamine D4 receptor von BELLIOTTI, T. R, BRINK, W. A, WISE, L. D, KESTEN, S. R, RUBIN, J. R, WUSTROW, D. J, ZOSKI, K. T, WHETZEL, S. Z, CORBIN, A. E, PUGSLEY, T. A, HEFFNER, T. G

Volltext

561 Development and first-in-human characterization of a potent oral CCR4 antagonist for the treatment of atopic dermatitis von Cheng, L.E., Jorapur, A., Jacobson, S., Talay, O., Miakicheva, S., Trujillo, D., Lee, N., Jankicevic, J., Wustrow, D., Kassner, P., Ho, W., Brockstedt, D.

Volltext

822 RPT193, a CCR4 inhibitor, improves the inflammatory skin transcriptomic profile in patients with atopic dermatitis von Guttman-Yassky, E., Pavel, A., Facheris, P., Correa Da Rosa, J., Pagan, A.D., Del Duca, E., Estrada, Y., Bissonnette, R., Kumar, M., Trujillo, D., Rulloda, J., Lee, N., Ikeda, S., Jankicevic, J., Wustrow, D., Brockstedt, D., Ho, W., Cheng, L., Kassner, P.

Volltext

Pyrazolo[1,5-a]pyrimidine CRF-1 receptor antagonists von Wustrow, David J., Capiris, Thomas, Rubin, Ronald, Knobelsdorf, James A., Akunne, Hyacinth, Davis, M.Duff, MacKenzie, Robert, Pugsley, Thomas A., Zoski, Kim T., Heffner, Thomas G., Wise, Lawrence D.

Volltext

A Series of 6- and 7-Piperazinyl- and -Piperidinylmethylbenzoxazinones with Dopamine D4 Antagonist Activity:  Discovery of a Potential Atypical Antipsychotic Agent von Belliotti, Thomas R, Wustrow, David J, Brink, Wouter A, Zoski, Kim T, Shih, Yu-Hsin, Whetzel, Steven Z, Georgic, Lynn M, Corbin, Ann E, Akunne, Hyacinth C, Heffner, Thomas G, Pugsley, Thomas A, Wise, Lawrence D

Volltext

Reduced Local Heating-mediated Nitric Oxide-dependent Cutaneous Vasodilation In Firefighters Following A Structural Training Burn: 2530 von Smith, Caroline J., Fearn, Katherine R., Morales, Favian A., Wustrow, Killian D., Trate, Dristen D., Galaska, Roman W., Hunnicutt, Lainey E., Collier, Scott R., Venier, Marta, Schlader, Zachary J.

Volltext

Time Course Of Dermal Anthracene Absorption Utilizing Intradermal Microdialysis: 2265 von Smith, Caroline J., Wustrow, Killian D., Sui, Xinyi, Demmler, Morgan, DenHartog, Emiel A., Collier, Scott R., Trate, Dristen D., Vinueza, Nelson R.

Volltext

Time Course Of Dermal Anthracene Absorption Utilizing Intradermal Microdialysis: 2265 von Smith, Caroline J., Wustrow, Killian D., Sui, Xinyi, Demmler, Morgan, DenHartog, Emiel A., Collier, Scott R., Trate, Dristen D., Vinueza, Nelson R.

Volltext

Effect Of Skin Temperature On Dermal Absorption Of Anthracene: 1146 Board #272 May 27 1:30 PM - 3:00 PM von Smith, Caroline J., Wustrow, Killian D., Root, Martin R., Collier, Scott R., DenHartog, Emiel A., Sui, Xinyi, Vinueza, Nelson R.

Volltext

Coupling of Arylboronic Acids with a Partially Reduced Pyridine Derivative von Wustrow, David J., Wise, Lawrence D.

Volltext

PD 158771, a potential antipsychotic agent with D2/D3 partial agonist and 5-HT(1A) agonist actions. II. Preclinical behavioral effects von Corbin, A E, Meltzer, L T, Ninteman, F W, Wiley, J N, Christoffersen, C L, Wustrow, D J, Wise, L D, Pugsley, T A, Heffner, T G

Volltext

Structure-activity relationships of pregabalin and analogues that target the alpha(2)-delta protein von Belliotti, Thomas R, Capiris, Thomas, Ekhato, I Victor, Kinsora, Jack J, Field, Mark J, Heffner, Thomas G, Meltzer, Leonard T, Schwarz, Jacob B, Taylor, Charles P, Thorpe, Andrew J, Vartanian, Mark G, Wise, Lawrence D, Zhi-Su, Ti, Weber, Mark L, Wustrow, David J

Volltext

3-[[(4-Aryl-1-piperazinyl)alkyl]cyclohexyl]-1H-indoles as Dopamine D2 Partial Agonists and Autoreceptor Agonists von Wustrow, David J, Smith, William J, Corbin, Ann E, Davis, M. Duff, Georgic, Lynn M, Pugsley, Thomas A, Whetzel, Steven Z, Heffner, Thomas G, Wise, Lawrence D

Volltext

Differential effects of the nonpeptide neurotensin antagonist, SR 48692, on the pharmacological effects of neurotensin agonists von Pugsley, T.A., Akunne, H.C., Whetzel, S.Z., Demattos, S., Corbin, A.E., Wiley, J.N., Wustrow, D.J., Wise, L.D., Heffner, T.G.

Volltext

Permeability of the blood-brain barrier to the neurotensin8-13 analog NT1 von BANKS, W. A, WUSTROW, D. J, CODY, W. L, DAVIS, M. D, KASTIN, A. J

Volltext

Novel small molecule neurotensin antagonists: 3-(1,5-diaryl-1,5-dioxopentan-3-yl)benzoic acids von Johnson, S.J., Akunne, H.C., Heffner, T.G., Kesten, S.R., Pugsley, T.A., Wise, L.D., Wustrow, D.J.

Volltext

N-Aryl-N'-Benzylpiperazines as Potential Antipsychotic Agents von Reitz, Allen B, Baxer, Ellen W, Bennett, Debra J, Codd, Ellen E, Jordan, Alfonzo D, Malloy, Elizabeth A, Maryanoff, Bruce E, McDonnell, Mark E, Ortegon, Marta E

Volltext

PD 158771, a potential antipsychotic agent with D2/D3 partial agonist and 5-HT1A agonist actions. II. Preclinical behavioral effects von CORBIN, A. E, MELTZER, L. T, NINTEMAN, F. W, WILEY, J. N, CHRISTOFFERSEN, C. L, WUSTROW, D. J, WISE, L. D, PUGSLEY, T. A, HEFFNER, T. G

Volltext