Formyl peptide receptor 2 and heart disease von Lupisella, John A., Shirude, Pravin S., Wurtz, Nicholas R., Garcia, Ricardo A.

Volltext

Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure von Asahina, Yoshikazu, Wurtz, Nicholas R, Arakawa, Kazuto, Carson, Nancy, Fujii, Kiyoshi, Fukuchi, Kazunori, Garcia, Ricardo, Hsu, Mei-Yin, Ishiyama, Junichi, Ito, Bruce, Kick, Ellen, Lupisella, John, Matsushima, Shingo, Ohata, Kohei, Ostrowski, Jacek, Saito, Yoshifumi, Tsuda, Kosuke, Villarreal, Francisco, Yamada, Hitomi, Yamaoka, Toshikazu, Wexler, Ruth, Gordon, David, Kohno, Yasushi

Volltext

Atropisomer Control in Macrocyclic Factor VIIa Inhibitors von Glunz, Peter W, Mueller, Luciano, Cheney, Daniel L, Ladziata, Vladimir, Zou, Yan, Wurtz, Nicholas R, Wei, Anzhi, Wong, Pancras C, Wexler, Ruth R, Priestley, E. Scott

Volltext

Synthesis of 35-Deoxy Amphotericin B Methyl Ester: A Strategy for Molecular Editing von Szpilman, Alex M, Cereghetti, Damiano M, Wurtz, Nicholas R, Manthorpe, Jeffrey M, Carreira, Erick M

Volltext

Discovery and Optimization of Aryl Piperidinone Ureas as Selective Formyl Peptide Receptor 2 Agonists von Wurtz, Nicholas R, Shirude, Pravin S, Cheney, Daniel L, Lupisella, John A, Chattopadhyay, Amit Kumar, Baligar, Vishweshwaraiah, Seshadri, Balaji, Anjanappa, Prakash, Viet, Andrew, Valente, Meriah N, Hsu, Mei-Yin, Abousleiman, Mojgan, Sarodaya, Sanket, Tagore, Debarati M, Dudhgaonkar, Shailesh, Putlur, Sivaprasad, Dierks, Elizabeth A, Ostrowski, Jacek, Wexler, Ruth R, Garcia, Ricardo, Kick, Ellen K

Volltext

Synthesis and Biophysical Studies on 35-Deoxy Amphotericin B Methyl Ester von Szpilman, Alex M., Cereghetti, Damiano M., Manthorpe, Jeffrey M., Wurtz, Nicholas R., Carreira, Erick M.

Volltext

Discovery of Heteroaryl Urea Isosteres for Formyl Peptide Receptor 2 Agonists von Wurtz, Nicholas R., Johnson, James A., Viet, Andrew, Shirude, Pravin S., Baligar, Vishweshwaraiah, Madduri, Sudhakara, Cheney, Daniel L., Park, Hyunsoo, Lupisella, John A., Hsu, Mei-Yin, Abousleiman, Mojgan, Galella, Michael A., Aulakh, Darpandeep, Dierks, Elizabeth A., Garcia, Ricardo A., Ostrowski, Jacek, Kick, Ellen K., Wexler, Ruth R.

Volltext

Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction von García, Ricardo A., Lupisella, John A., Ito, Bruce R., Hsu, Mei-Yin, Fernando, Gayani, Carson, Nancy L., Allocco, John J., Ryan, Carol S., Zhang, Rongan, Wang, Zhaoqing, Heroux, Madeleine, Carrier, Marilyn, St.-Onge, Stéphane, Bouvier, Michel, Dudhgaonkar, Shailesh, Nagar, Jignesh, Bustamante-Pozo, Moises M., Garate-Carrillo, Alejandra, Chen, Jian, Ma, Xiuying, Search, Debra J., Dierks, Elizabeth A., Kick, Ellen K., Wexler, Ruth R., Gordon, David A., Ostrowski, Jacek, Wurtz, Nicholas R., Villarreal, Francisco

Volltext

Discovery of a Highly Potent, Selective, and Orally Bioavailable Macrocyclic Inhibitor of Blood Coagulation Factor VIIa–Tissue Factor Complex von Zhang, Xiaojun, Glunz, Peter W, Johnson, James A, Jiang, Wen, Jacutin-Porte, Swanee, Ladziata, Vladimir, Zou, Yan, Phillips, Monique S, Wurtz, Nicholas R, Parkhurst, Brandon, Rendina, Alan R, Harper, Timothy M, Cheney, Daniel L, Luettgen, Joseph M, Wong, Pancras C, Seiffert, Dietmar, Wexler, Ruth R, Priestley, E. Scott

Volltext

Potent Triazolopyridine Myeloperoxidase Inhibitors von Wurtz, Nicholas R, Viet, Andrew, Shaw, Scott A, Dilger, Andrew, Valente, Meriah N, Khan, Javed A, Jusuf, Sutjano, Narayanan, Rangaraj, Fernando, Gayani, Lo, Fred, Liu, Xiaoqin, Locke, Gregory A, Kopcho, Lisa, Abell, Lynn M, Sleph, Paul, Basso, Michael, Zhao, Lei, Wexler, Ruth R, Duclos, Franck, Kick, Ellen K

Volltext

Correction to “Atropisomer Control in Macrocyclic Factor VIIa Inhibitors” von Glunz, Peter W, Mueller, Luciano, Cheney, Daniel L, Ladziata, Vladimir, Zou, Yan, Wurtz, Nicholas R, Wei, Anzhi, Wong, Pancras C, Wexler, Ruth R, Priestley, E. Scott

Volltext

Discovery of Novel P1 Groups for Coagulation Factor VIIa Inhibition Using Fragment-Based Screening von Cheney, Daniel L, Bozarth, Jeffrey M, Metzler, William J, Morin, Paul E, Mueller, Luciano, Newitt, John A, Nirschl, Alexandra H, Rendina, Alan R, Tamura, James K, Wei, Anzhi, Wen, Xiao, Wurtz, Nicholas R, Seiffert, Dietmar A, Wexler, Ruth R, Priestley, E. Scott

Volltext

Molecular Mechanisms of Desensitization Underlying the Differential Effects of Formyl Peptide Receptor 2 Agonists on Cardiac Structure–Function Post Myocardial Infarction von Lupisella, John, St-Onge, Stéphane, Carrier, Marilyn, Cook, Erica M., Wang, Tao, Sum, Chi, Fernando, Gayani, Apgar, Kendra, Zhang, Rongan, Carson, Nancy, Snyder, Bradley J., Ryan, Carol S., Ma, Xiuying, Dierks, Elizabeth A., Little, Sean, Kick, Ellen K., Wurtz, Nicholas R., Bouvier, Michel, Héroux, Madeleine, Garcia, Ricardo A.

Volltext

Neutral macrocyclic factor VIIa inhibitors von Wurtz, Nicholas R., Parkhurst, Brandon L., DeLucca, Indawati, Glunz, Peter W., Jiang, Wen, Zhang, Xiaojun, Cheney, Daniel L., Bozarth, Jeffrey M., Rendina, Alan R., Wei, Anzhi, Harper, Tim, Luettgen, Joseph M., Wu, Yiming, Wong, Pancras C., Seiffert, Dietmar A., Wexler, Ruth R., Priestley, E. Scott

Volltext

Fmoc Solid Phase Synthesis of Polyamides Containing Pyrrole and Imidazole Amino Acids von Wurtz, Nicholas R, Turner, James M, Baird, Eldon E, Dervan, Peter B

Volltext

Triazolopyrimidines identified as reversible myeloperoxidase inhibitors von Duclos, Franck, Abell, Lynn M, Harden, David G, Pike, Kristen, Nowak, Kimberly, Locke, Gregory A, Duke, Gerald J, Liu, Xiaoqin, Fernando, Gayani, Shaw, Scott A, Vokits, Benjamin P, Wurtz, Nicholas R, Viet, Andrew, Valente, Meriah N, Stachura, Sylwia, Sleph, Paul, Khan, Javed A, Gao, Ji, Dongre, Ashok R, Zhao, Lei, Wexler, Ruth R, Gordon, David A, Kick, Ellen K

Volltext

Discovery of Phenylglycine Lactams as Potent Neutral Factor VIIa Inhibitors von Wurtz, Nicholas R, Parkhurst, Brandon L, Jiang, Wen, DeLucca, Indawati, Zhang, Xiaojun, Ladziata, Vladimir, Cheney, Daniel L, Bozarth, Jeffrey R, Rendina, Alan R, Wei, Anzhi, Luettgen, Joseph M, Wu, Yiming, Wong, Pancras C, Seiffert, Dietmar A, Wexler, Ruth R, Priestley, E. Scott

Volltext

Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment von García, Ricardo A., Ito, Bruce R., Lupisella, John A., Carson, Nancy A., Hsu, Mei-Yin, Fernando, Gayani, Heroux, Madeleine, Bouvier, Michel, Dierks, Elizabeth, Kick, Ellen K., Gordon, David A., Chen, Jian, Mintier, Gabe, Carrier, Marilyn, St-Onge, Stéphane, Shah, Himanshu, Towne, Jordan, Bucardo, Marcela Sotelo, Ma, Xiuying, Ryan, Carol S., Wurtz, Nicholas R., Ostrowski, Jacek, Villarreal, Francisco J.

Volltext

Design and Synthesis of Phenylpyrrolidine Phenylglycinamides As Highly Potent and Selective TF-FVIIa Inhibitors von Zhang, Xiaojun, Jiang, Wen, Jacutin-Porte, Swanee, Glunz, Peter W, Zou, Yan, Cheng, Xuhong, Nirschl, Alexandra H, Wurtz, Nicholas R, Luettgen, Joseph M, Rendina, Alan R, Luo, Gang, Harper, Timothy M, Wei, Anzhi, Anumula, Rushith, Cheney, Daniel L, Knabb, Robert M, Wong, Pancras C, Wexler, Ruth R, Priestley, E. Scott

Volltext

DNA crosslinking and biological activity of a hairpin polyamide–chlorambucil conjugate von Wang, Yong‐Dong, Dziegielewski, Jaroslaw, Wurtz, Nicholas R., Dziegielewska, Barbara, Dervan, Peter B., Beerman, Terry A.

Volltext