Strategies for designing synthetic immune agonists von Wu, Tom Y.‐H.

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Incorporation of Phosphonate into Benzonaphthyridine Toll-like Receptor 7 Agonists for Adsorption to Aluminum Hydroxide von Cortez, Alex, Li, Yongkai, Miller, Andrew T, Zhang, Xiaoyue, Yue, Kathy, Maginnis, Jillian, Hampton, Janice, Hall, De Shon, Shapiro, Michael, Nayak, Bishnu, D’Oro, Ugo, Li, Chun, Skibinski, David, Mbow, M. Lamine, Singh, Manmohan, O’Hagan, Derek T, Cooke, Michael P, Valiante, Nicholas M, Wu, Tom Y.-H

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A Dual Inhibitor of DYRK1A and GSK3β for β‐Cell Proliferation: Aminopyrazine Derivative GNF4877 von Liu, Yahu A., Jin, Qihui, Ding, Qiang, Hao, Xueshi, Mo, Tingting, Yan, Shanshan, Zou, Yefen, Huang, Zhihong, Zhang, Xiaoyue, Gao, Wenqi, Wu, Tom Y.‐H., Li, Chun, Bursalaya, Badry, Di Donato, Michael, Zhang, You‐Qing, Deaton, Lisa, Shen, Weijun, Taylor, Brandon, Kamireddy, Anwesh, Harb, George, Li, Jing, Jia, Yong, Schumacher, Andrew M., Laffitte, Bryan, Glynne, Richard, Pan, Shifeng, McNamara, Peter, Molteni, Valentina, Loren, Jon

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Pancreas-Specific Delivery of β-Cell Proliferating Small Molecules von Hao, Xueshi, Jin, Qihui, Va, Porino, Li, Chun, Shen, Weijun, Laffitte, Bryan, Wu, Tom Y.-H.

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Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6‑Azaindole Derivative GNF2133 von Liu, Yahu A, Jin, Qihui, Zou, Yefen, Ding, Qiang, Yan, Shanshan, Wang, Zhicheng, Hao, Xueshi, Nguyen, Bao, Zhang, Xiaoyue, Pan, Jianfeng, Mo, Tingting, Jacobsen, Kate, Lam, Thanh, Wu, Tom Y.-H, Petrassi, H. Michael, Bursulaya, Badry, DiDonato, Michael, Gordon, W. Perry, Liu, Bo, Baaten, Janine, Hill, Robert, Nguyen-Tran, Vân, Qiu, Minhua, Zhang, You-Qing, Kamireddy, Anwesh, Espinola, Sheryll, Deaton, Lisa, Ha, Sukwon, Harb, George, Jia, Yong, Li, Jing, Shen, Weijun, Schumacher, Andrew M, Colman, Karyn, Glynne, Richard, Pan, Shifeng, McNamara, Peter, Laffitte, Bryan, Meeusen, Shelly, Molteni, Valentina, Loren, Jon

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Discovery of 5‑(3,4-Difluorophenyl)-3-(pyrazol-4-yl)-7-azaindole (GNF3809) for β‑Cell Survival in Type 1 Diabetes von Huang, Zhihong, Tremblay, Matthew S, Wu, Tom Y.-H, Ding, Qiang, Hao, Xueshi, Baaten, Janine, Hill, Robert, Liu, Bo, Meeusen, Shelly, Zou, Yefen, Yan, Shanshan, Jia, Yong, Nguyen-Tran, Van, Shen, Weijun, Bhat, Ganesh, Glynne, Richard, Laffitte, Bryan, Li, Jing, Molteni, Valentina, Liu, Yahu A

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Synthetic Small Molecules That Control Stem Cell Fate von Ding, Sheng, Tom Y. H. Wu, Brinker, Achim, Peters, Eric C., Hur, Wooyoung, Gray, Nathanael S., Schultz, Peter G.

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Liver‐Targeted Toll‐Like Receptor 7 Agonist Combined With Entecavir Promotes a Functional Cure in the Woodchuck Model of Hepatitis B Virus von Korolowizc, Kyle E., Li, Bin, Huang, Xu, Yon, Changsuek, Rodrigo, Evelyn, Corpuz, Manny, Plouffe, David M., Kallakury, Bhaskar V., Suresh, Manasa, Wu, Tom Y.‐H., Miller, Andrew T., Menne, Stephan

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A new TLR2 agonist promotes cross-presentation by mouse and human antigen presenting cells von Santone, Melissa, Aprea, Susanna, Wu, Tom Y H, Cooke, Michael P, Mbow, M Lamine, Valiante, Nicholas M, Rush, James S, Dougan, Stephanie, Avalos, Ana, Ploegh, Hidde, De Gregorio, Ennio, Buonsanti, Cecilia, D'Oro, Ugo

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One-Pot Two-Step Microwave-Assisted Reaction in Constructing 4,5-Disubstituted Pyrazolopyrimidines von Wu, Tom Y. H, Schultz, Peter G, Ding, Sheng

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Stable Nanoemulsions for the Delivery of Small Molecule Immune Potentiators von Lodaya, Rushit N., Brito, Luis A., Wu, Tom Y.H., Miller, Andrew T., Otten, Gillis R., Singh, Manmohan, O'Hagan, Derek T.

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A Versatile Linkage Strategy for Solid-Phase Synthesis of N,N-Dimethyltryptamines and β-Carbolines von Wu, Tom Y. H, Schultz, Peter G

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Biarylimidazoles as inhibitors of microsomal prostaglandin E2 synthase-1 von WU, Tom Y. H, JUTEAU, Hélène, BRIDEAU, Christine, DUCHARME, Yves, FRIESEN, Richard W, GUIRAL, Sébastien, DUFRESNE, Lynn, POIRIER, Hugo, SALEM, Myriam, RIENDEAU, Denis, MANCINI, Joseph

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Solid-Phase Synthesis of 2,3,5-Trisubstituted Indoles von Wu, Tom Y. H, Ding, Sheng, Gray, Nathanael S, Schultz, Peter G

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Design, synthesis, and activity of HDAC inhibitors with a N-formyl hydroxylamine head group von Wu, Tom Y.H., Hassig, Christian, Wu, Yiqin, Ding, Sheng, Schultz, Peter G.

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Abstract 684: Gastrointestinal/liver-targeted TLR7 agonist for treatment of colorectal and liver cancers von Miller, Andrew T., Rodrigo, Evelyn, Corpuz, Manny, Plouffe, David, Wu, Tom Y.-H.

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Pancreas-Specific Delivery of [beta]-Cell Proliferating Small Molecules von Hao, Xueshi, Jin, Qihui, Va, Porino, Li, Chun, Shen, Weijun, Laffitte, Bryan, Wu, Tom Y-H

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Biarylimidazoles as inhibitors of microsomal prostaglandin E 2 synthase-1 von Wu, Tom Y.H., Juteau, Hélène, Ducharme, Yves, Friesen, Richard W., Guiral, Sébastien, Dufresne, Lynn, Poirier, Hugo, Salem, Myriam, Riendeau, Denis, Mancini, Joseph, Brideau, Christine

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Topical SMIP-7.7, a Toll–Like Receptor 7 Agonist, Protects against Genital Herpes Simplex Virus Type-2 Disease in the Guinea Pig Model of Genital Herpes von Bernstein, David I, Cardin, Rhonda D, Bravo, Fernando J, Earwood, Julie, Clark, Jennifer R, Li, Yongkai, Mishra, Pranab, Li, Chun, Nayak, Bishnu P, Miller, Andrew T, Wu, Tom Y-H, Cooke, Michael P, Valiante, Nicholas M

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Applying chemical tools to the discovery of novel regenerative medicine von Wu, Tom Y.H., Ding, Sheng

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