The life cycle of cancer-associated fibroblasts within the tumour stroma and its importance in disease outcome von D’Arcangelo, Elisa, Wu, Nila C., Cadavid, Jose L., McGuigan, Alison P.

Volltext

An off-the-shelf multi-well scaffold-supported platform for tumour organoid-based tissues von Li, Nancy T., Wu, Nila C., Cao, Ruonan, Cadavid, Jose L., Latour, Simon, Lu, Xiaoya, Zhu, Yutong, Mijalkovic, Mirjana, Roozitalab, Reza, Landon-Brace, Natalie, Notta, Faiyaz, McGuigan, Alison P.

Volltext

3D microgels to quantify tumor cell properties and therapy response dynamics von Wu, Nila C., Cadavid, Jose L., Tan, Xinzhu, Latour, Simon, Scaini, Stefano, Makhijani, Priya, McGaha, Tracy L., Ailles, Laurie, McGuigan, Alison P.

Volltext

The use of a multi-metric readout screen to identify EHMT2/G9a-inhibition as a modulator of cancer-associated fibroblast activation state von Wu, Nila C., Quevedo, Rene, Nurse, Michelle, Hezaveh, Kebria, Liu, Haijiao, Sun, Fumao, Muffat, Julien, Sun, Yu, Simmons, Craig A., McGaha, Tracy L., Prinos, Panagiotis, Arrowsmith, Cheryl H., Ailles, Laurie, D'Arcangelo, Elisa, McGuigan, Alison P.

Volltext

Gels for Live Analysis of Compartmentalized Environments (GLAnCE): A tissue model to probe tumour phenotypes at tumour-stroma interfaces von D'Arcangelo, Elisa, Wu, Nila C., Chen, Tianhao, Shahaj, Andi, Cadavid, Jose L., Huang, Linwen, Ailles, Laurie, McGuigan, Alison P.

Volltext

An Engineered Patient‐Derived Tumor Organoid Model That Can Be Disassembled to Study Cellular Responses in a Graded 3D Microenvironment von Landon‐Brace, Natalie, Cadavid, Jose L., Latour, Simon, Co, Ileana L., Rodenhizer, Darren, Li, Nancy T., Wu, Nila C., Bugbee, Eryn, Chebotarev, Aleks, Zhang, Ji, Wouters, Bradly G., McGuigan, Alison P.

Volltext

Applications of Omics Technologies for Three-Dimensional In Vitro Disease Models von Pieters, Vera M, Co, Ileana L, Wu, Nila C, McGuigan, Alison P

Volltext

A bispecific antibody-drug conjugate targeting pCAD and CDH17 has antitumor activity and improved tumor-specificity von Synan, Alyssa, Wu, Nila C., Velazquez, Roberto, Gesner, Thomas, Logel, Claude, Mueller, Kathrin, Green, Andrew, Barzaghi-Rinaudo, Patrizia, Simmons, Quincey, Mercan, Samuele, Shi, Xingyi, Li, Xun, Sagar, Vivek, Korn, Joshua, McLaughlin, Margaret, Tschantz, William R., Hainzl, Dominik, Malamas, Anthony, Huber, Thomas, Cebe, Regis, Xie, Kathleen T., D’Alessio, Joseph A.

Volltext