Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer von Chen, Yang, Yang, Sujuan, Tavormina, Jena, Tampe, Desiree, Zeisberg, Michael, Wang, Huamin, Mahadevan, Krishnan K., Wu, Chang-Jiun, Sugimoto, Hikaru, Chang, Chia-Chi, Jenq, Robert R., McAndrews, Kathleen M., Kalluri, Raghu

Volltext

Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer von Kapoor, Avnish, Yao, Wantong, Ying, Haoqiang, Hua, Sujun, Liewen, Alison, Wang, Qiuyun, Zhong, Yi, Wu, Chang-Jiun, Sadanandam, Anguraj, Hu, Baoli, Chang, Qing, Chu, Gerald C., Al-Khalil, Ramsey, Jiang, Shan, Xia, Hongai, Fletcher-Sananikone, Eliot, Lim, Carol, Horwitz, Gillian I., Viale, Andrea, Pettazzoni, Piergiorgio, Sanchez, Nora, Wang, Huamin, Protopopov, Alexei, Zhang, Jianhua, Heffernan, Timothy, Johnson, Randy L., Chin, Lynda, Wang, Y. Alan, Draetta, Giulio, DePinho, Ronald A.

Volltext

Why is melanoma so metastatic? von Braeuer, Russell R., Watson, Ian R., Wu, Chang-Jiun, Mobley, Aaron K., Kamiya, Takafumi, Shoshan, Einav, Bar-Eli, Menashe

Volltext

SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression von Ding, Zhihu, Wu, Chang-Jiun, Chu, Gerald C., Xiao, Yonghong, Ho, Dennis, Zhang, Jingfang, Perry, Samuel R., Labrot, Emma S., Wu, Xiaoqiu, Lis, Rosina, Hoshida, Yujin, Hiller, David, Hu, Baoli, Jiang, Shan, Zheng, Hongwu, Stegh, Alexander H., Scott, Kenneth L., Signoretti, Sabina, Bardeesy, Nabeel, Wang, Y. Alan, Hill, David E., Golub, Todd R., Stampfer, Meir J., Wong, Wing H., Loda, Massimo, Mucci, Lorelei, Chin, Lynda, DePinho, Ronald A.

Volltext

USP21 deubiquitinase promotes pancreas cancer cell stemness via Wnt pathway activation von Hou, Pingping, Ma, Xingdi, Zhang, Qiang, Wu, Chang-Jiun, Liao, Wenting, Li, Jun, Wang, Huamin, Zhao, Jun, Zhou, Xin, Guan, Carolyn, Ackroyd, Jeffery, Jiang, Shan, Zhang, Jianhua, Spring, Denise J, Wang, Y Alan, DePinho, Ronald A

Volltext

ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma von Marchesini, Matteo, Ogoti, Yamini, Fiorini, Elena, Aktas Samur, Anil, Nezi, Luigi, D'Anca, Marianna, Storti, Paola, Samur, Mehmet Kemal, Ganan-Gomez, Irene, Fulciniti, Maria Teresa, Mistry, Nipun, Jiang, Shan, Bao, Naran, Marchica, Valentina, Neri, Antonino, Bueso-Ramos, Carlos, Wu, Chang-Jiun, Zhang, Li, Liang, Han, Peng, Xinxin, Giuliani, Nicola, Draetta, Giulio, Clise-Dwyer, Karen, Kantarjian, Hagop, Munshi, Nikhil, Orlowski, Robert, Garcia-Manero, Guillermo, DePinho, Ronald A., Colla, Simona

Volltext

Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer von Chen, Yang, Kim, Jiha, Yang, Sujuan, Wang, Huamin, Wu, Chang-Jiun, Sugimoto, Hikaru, LeBleu, Valerie S., Kalluri, Raghu

Volltext

AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylase von Yoshihama, Yohei, LaBella, Kyle A., Kim, Eiru, Bertolet, Lori, Colic, Medina, Li, Jiexi, Shang, Xiaoying, Wu, Chang-Jiun, Spring, Denise J., Wang, Y. Alan, Hart, Traver, DePinho, Ronald A.

Volltext

Differential Characteristics on TCR Embedding Landscape Among Immune Checkpoint Blockade Responders Versus Non-Responders Against Non-Small Cell Lung Carcinoma von Tsou, Peiling, Wu, Chang-Jiun

Volltext

Sex-Dimorphic Association of Plasma Fatty Acids with Cardiovascular Fitness in Young and Middle-Aged General Adults: Subsamples from NHANES 2003⁻2004 von Tsou, Pei-Ling, Wu, Chang-Jiun

Volltext

Diagnostic rate of germline pathogenic variants in pancreatic ductal adenocarcinoma patients using whole genome sequencing von Chung, An-Ko, Lin, Ro-Ting, Yeh, Chun-Chieh, Yang, Chi-Ying, Wu, Chang-Jiun, Chen, Pei-Lung, Lin, Jaw-Town

Volltext

An In Vivo Screen Identifies PYGO2 as a Driver for Metastatic Prostate Cancer von Lu, Xin, Pan, Xiaolu, Wu, Chang-Jiun, Zhao, Di, Feng, Shan, Zang, Yong, Lee, Rumi, Khadka, Sunada, Amin, Samirkumar B, Jin, Eun-Jung, Shang, Xiaoying, Deng, Pingna, Luo, Yanting, Morgenlander, William R, Weinrich, Jacqueline, Lu, Xuemin, Jiang, Shan, Chang, Qing, Navone, Nora M, Troncoso, Patricia, DePinho, Ronald A, Wang, Y Alan

Volltext

Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes von Scott, Kenneth L., Nogueira, Cristina, Heffernan, Timothy P., van Doorn, Remco, Dhakal, Sabin, Hanna, Jason A., Min, Chengyin, Jaskelioff, Mariela, Xiao, Yonghong, Wu, Chang-Jiun, Cameron, Lisa A., Perry, Samuel R., Zeid, Rhamy, Feinberg, Tamar, Kim, Minjung, Vande Woude, George, Granter, Scott R., Bosenberg, Marcus, Chu, Gerald C., DePinho, Ronald A., Rimm, David L., Chin, Lynda

Volltext

Classifying driver mutations of papillary thyroid carcinoma on whole slide image: an automated workflow applying deep convolutional neural network von Tsou, Peiling, Wu, Chang-Jiun

Volltext

The art of gene function prediction von Murali, T M, Wu, Chang-Jiun, Kasif, Simon

Volltext

Tumor Microenvironment Remodeling Enables Bypass of Oncogenic KRAS Dependency in Pancreatic Cancer von Hou, Pingping, Kapoor, Avnish, Zhang, Qiang, Li, Jiexi, Wu, Chang-Jiun, Li, Jun, Lan, Zhengdao, Tang, Ming, Ma, Xingdi, Ackroyd, Jeffrey J, Kalluri, Raghu, Zhang, Jianhua, Jiang, Shan, Spring, Denise J, Wang, Y Alan, DePinho, Ronald A

Volltext

Comprehensive T cell repertoire characterization of non-small cell lung cancer von Reuben, Alexandre, Zhang, Jiexin, Chiou, Shin-Heng, Gittelman, Rachel M., Li, Jun, Lee, Won-Chul, Fujimoto, Junya, Behrens, Carmen, Liu, Xiaoke, Wang, Feng, Quek, Kelly, Wang, Chunlin, Kheradmand, Farrah, Chen, Runzhe, Chow, Chi-Wan, Lin, Heather, Bernatchez, Chantale, Jalali, Ali, Hu, Xin, Wu, Chang-Jiun, Eterovic, Agda Karina, Parra, Edwin Roger, Yusko, Erik, Emerson, Ryan, Benzeno, Sharon, Vignali, Marissa, Wu, Xifeng, Ye, Yuanqing, Little, Latasha D., Gumbs, Curtis, Mao, Xizeng, Song, Xingzhi, Tippen, Samantha, Thornton, Rebecca L., Cascone, Tina, Snyder, Alexandra, Wargo, Jennifer A., Herbst, Roy, Swisher, Stephen, Kadara, Humam, Moran, Cesar, Kalhor, Neda, Zhang, Jianhua, Scheet, Paul, Vaporciyan, Ara A., Sepesi, Boris, Gibbons, Don L., Robins, Harlan, Hwu, Patrick, Heymach, John V., Sharma, Padmanee, Allison, James P., Baladandayuthapani, Veera, Lee, Jack J., Davis, Mark M., Wistuba, Ignacio I., Futreal, P. Andrew, Zhang, Jianjun

Volltext

Histone demethylase KDM5D upregulation drives sex differences in colon cancer von Li, Jiexi, Lan, Zhengdao, Liao, Wenting, Horner, James W., Xu, Xueping, Liu, Jielin, Yoshihama, Yohei, Jiang, Shan, Shim, Hong Seok, Slotnik, Max, LaBella, Kyle A., Wu, Chang-Jiun, Dunner, Kenneth, Hsu, Wen-Hao, Lee, Rumi, Khanduri, Isha, Terranova, Christopher, Akdemir, Kadir, Chakravarti, Deepavali, Shang, Xiaoying, Spring, Denise J., Wang, Y. Alan, DePinho, Ronald A.

Volltext

Chromatin Regulator CHD1 Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer von Zhao, Di, Cai, Li, Lu, Xin, Liang, Xin, Li, Jiexi, Chen, Peiwen, Ittmann, Michael, Shang, Xiaoying, Jiang, Shan, Li, Haoyan, Meng, Chenling, Flores, Ivonne, Song, Jian H, Horner, James W, Lan, Zhengdao, Wu, Chang-Jiun, Li, Jun, Chang, Qing, Chen, Ko-Chien, Wang, Guocan, Deng, Pingna, Spring, Denise J, Wang, Y Alan, DePinho, Ronald A

Volltext

Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression von Wang, Guocan, Lu, Xin, Dey, Prasenjit, Deng, Pingna, Wu, Chia Chin, Jiang, Shan, Fang, Zhuangna, Zhao, Kun, Konaparthi, Ramakrishna, Hua, Sujun, Zhang, Jianhua, Li-Ning-Tapia, Elsa M, Kapoor, Avnish, Wu, Chang-Jiun, Patel, Neelay Bhaskar, Guo, Zhenglin, Ramamoorthy, Vandhana, Tieu, Trang N, Heffernan, Tim, Zhao, Di, Shang, Xiaoying, Khadka, Sunada, Hou, Pingping, Hu, Baoli, Jin, Eun-Jung, Yao, Wantong, Pan, Xiaolu, Ding, Zhihu, Shi, Yanxia, Li, Liren, Chang, Qing, Troncoso, Patricia, Logothetis, Christopher J, McArthur, Mark J, Chin, Lynda, Wang, Y Alan, DePinho, Ronald A

Volltext