ATP Hydrolysis in Eg5 Kinesin Involves a Catalytic Two-water Mechanism von Parke, Courtney L., Wojcik, Edward J., Kim, Sunyoung, Worthylake, David K.

Volltext

The Structural Basis for Cdc42-Induced Dimerization of IQGAPs von LeCour, Louis, Boyapati, Vamsi. K., Liu, Jing, Li, Zhigang, Sacks, David B., Worthylake, David K.

Volltext

Circulating Plasma Exosomal Proteins of Either SHIV-Infected Rhesus Macaque or HIV-Infected Patient Indicates a Link to Neuropathogenesis von Chandra, Partha K, Braun, Stephen E, Maity, Sudipa, Castorena-Gonzalez, Jorge A, Kim, Hogyoung, Shaffer, Jeffrey G, Cikic, Sinisa, Rutkai, Ibolya, Fan, Jia, Guidry, Jessie J, Worthylake, David K, Li, Chenzhong, Abdel-Mageed, Asim B, Busija, David W

Volltext

Selective cytotoxicity of a novel immunotoxin based on pulchellin A chain for cells expressing HIV envelope von Sadraeian, Mohammad, Guimarães, Francisco E. G., Araújo, Ana P. U., Worthylake, David K., LeCour, Louis Jr, Pincus, Seth H.

Volltext

Crystal structure of Rac1 bound to its effector phospholipase C-β2 von Sondek, John, Jezyk, Mark R, Snyder, Jason T, Gershberg, Svetlana, Worthylake, David K, Harden, T Kendall

Volltext

Allosteric Drug Discrimination Is Coupled to Mechanochemical Changes in the Kinesin-5 Motor Core von Kim, Elizabeth D., Buckley, Rebecca, Learman, Sarah, Richard, Jessica, Parke, Courtney, Worthylake, David K., Wojcik, Edward J., Walker, Richard A., Kim, Sunyoung

Volltext

Structural basis for the selective activation of Rho GTPases by Dbl exchange factors von Sondek, John, Snyder, Jason T, Worthylake, David K, Rossman, Kent L, Betts, Laurie, Pruitt, Wendy M, Siderovski, David P, Der, Channing J

Volltext

Crystal Structure of the GTPase-activating Protein-related Domain from IQGAP1 von Kurella, Vinodh B., Richard, Jessica M., Parke, Courtney L., LeCour, Louis F., Bellamy, Henry D., Worthylake, David K.

Volltext

A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange von Rossman, Kent L., Worthylake, David K., Snyder, Jason T., Siderovski, David P., Campbell, Sharon L., Sondek, John

Volltext

Structure of the Carboxyl-Terminal Dimerization Domain of the HIV-1 Capsid Protein von Gamble, Theresa R., Yoo, Sanghee, Vajdos, Felix F., von Schwedler, Uta K., Worthylake, David K., Wang, Hui, McCutcheon, John P., Sundquist, Wesley I., Hill, Christopher P.

Volltext

Crystal Structure of Human Cyclophilin A Bound to the Amino-Terminal Domain of HIV-1 Capsid von Gamble, Theresa R, Vajdos, Felix F, Yoo, Sanghee, Worthylake, David K, Houseweart, Megan, Sundquist, Wesley I, Hill, Christopher P

Volltext

Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42 von Gorisse, Laëtitia, Li, Zhigang, Wagner, Craig D., Worthylake, David K., Zappacosta, Francesca, Hedman, Andrew C., Annan, Roland S., Sacks, David B.

Volltext

Small Molecule Anticancer Compound Modulates Cell Cycle DNA Damage Response Pathway and Inhibit Tumorigenesis in Triple Negative Breast Cancer von Okpechi, Samuel C., Dong, Shengli, Yousefi, Hassan, Guidry, Jessie J., Otohinoyi, David A., Worthylake, David K., Hicks, Chindo, Alahari, Suresh K.

Volltext

Circulating Exosomal Proteins are linked to Neuropathogenesis in SIV‐infected Rhesus Macaque: A Proteomic Approach von Chandra, Partha K., Braun, Stephen E., Baddoo, Melody C., Kim, Hogyoung, Castorena‐Gonzalez, Jorge A., Cikic, Sinisa, Rutkai, Ibolya, Guidry, Jessie J., Worthylake, David K., Flemington, Erik K., Abdel‐Mageed, Asim B., Busija, David W.

Volltext

The IQGAP1 N‑Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F‑Actin and Calcium-Bound Calmodulin von Liu, Jing, Kurella, Vinodh B, LeCour, Louis, Vanagunas, Tomas, Worthylake, David K

Volltext

Conserved Sequence Repeats of IQGAP1 Mediate Binding to Ezrin von Liu, Jing, Guidry, Jesse J, Worthylake, David K

Volltext

Molecular basis for Rac1 recognition by guanine nucleotide exchange factors von Der, Channing J, Karnoub, Antoine E, Worthylake, David K, Rossman, Kent L, Pruitt, Wendy Morse, Campbell, Sharon L, Sondek, John

Volltext

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1 von Sondek, John, Worthylake, David K, Rossman, Kent L

Volltext

The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation von Chhatriwala, Mariya K., Betts, Laurie, Worthylake, David K., Sondek, John

Volltext

Crystal Structure of the DH/PH Fragment of Dbs without Bound GTPase von Worthylake, David K, Rossman, Kent L, Sondek, John

Volltext