Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity von Ramms, Bastian, Pollow, Dennis P, Zhu, Han, Nora, Chelsea, Harrington, Austin R, Omar, Ibrahim, Gordts, Philip L S M, Wortham, Matthew, Sander, Maike

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Endoplasmic reticulum tubules limit the size of misfolded protein condensates von Parashar, Smriti, Chidambaram, Ravi, Chen, Shuliang, Liem, Christina R, Griffis, Eric, Lambert, Gerard G, Shaner, Nathan C, Wortham, Matthew, Hay, Jesse C, Ferro-Novick, Susan

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LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development von Vinckier, Nicholas K., Patel, Nisha A., Geusz, Ryan J., Wang, Allen, Wang, Jinzhao, Matta, Ileana, Harrington, Austin R., Wortham, Matthew, Wetton, Nichole, Wang, Jianxun, Jhala, Ulupi S., Rosenfeld, Michael G., Benner, Christopher W., Shih, Hung-Ping, Sander, Maike

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Nutrient regulation of the islet epigenome controls adaptive insulin secretion von Wortham, Matthew, Liu, Fenfen, Harrington, Austin R, Fleischman, Johanna Y, Wallace, Martina, Mulas, Francesca, Mallick, Medhavi, Vinckier, Nicholas K, Cross, Benjamin R, Chiou, Joshua, Patel, Nisha A, Sui, Yinghui, McGrail, Carolyn, Jun, Yesl, Wang, Gaowei, Jhala, Ulupi S, Schüle, Roland, Shirihai, Orian S, Huising, Mark O, Gaulton, Kyle J, Metallo, Christian M, Sander, Maike

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Transcriptional mechanisms of pancreatic β-cell maturation and functional adaptation von Wortham, Matthew, Sander, Maike

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Transcriptional mechanisms of pancreatic 13-cell maturation and functional adaptation von Wortham, Matthew, Sander, Maike

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Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding von Urizar, Adriana Ibarra, Prause, Michala, Ingerslev, Lars Roed, Wortham, Matthew, Sui, Yinghui, Sander, Maike, Williams, Kristine, Barrès, Romain, Larsen, Martin R., Christensen, Gitte Lund, Billestrup, Nils

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Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function von Wortham, Matthew, Benthuysen, Jacqueline R., Wallace, Martina, Savas, Jeffrey N., Mulas, Francesca, Divakaruni, Ajit S., Liu, Fenfen, Albert, Verena, Taylor, Brandon L., Sui, Yinghui, Saez, Enrique, Murphy, Anne N., Yates, John R., Metallo, Christian M., Sander, Maike

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Global identification of MLL2-targeted loci reveals MLL2’s role in diverse signaling pathways von Guo, Changcun, Chang, Chun-Chi, Wortham, Matthew, Chen, Lee H, Kernagis, Dawn N, Qin, Xiaoxia, Cho, Young-Wook, Chi, Jen-Tsan, Grant, Gerald A, McLendon, Roger E, Yan, Hai, Ge, Kai, Papadopoulos, Nickolas, Bigner, Darell D, He, Yiping

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Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection von Shibata, Yoichiro, Sheffield, Nathan C, Fedrigo, Olivier, Babbitt, Courtney C, Wortham, Matthew, Tewari, Alok K, London, Darin, Song, Lingyun, Lee, Bum-Kyu, Iyer, Vishwanath R, Parker, Stephen C J, Margulies, Elliott H, Wray, Gregory A, Furey, Terrence S, Crawford, Gregory E

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OTX2 Is Critical for the Maintenance and Progression of Shh-Independent Medulloblastomas von ADAMSON, David C, QUN SHI, HAI YAN, WORTHAM, Matthew, NORTHCOTT, Paul A, CHUNHUI DI, DUNCAN, Christopher G, JIANJUN LI, MCLENDON, Roger E, BIGNER, Darell D, TAYLOR, Michael D

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Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance von Shum, Michael, Segawa, Mayuko, Gharakhanian, Raffi, Viñuela, Ana, Wortham, Matthew, Baghdasarian, Siyouneh, Wolf, Dane M., Sereda, Samuel B., Nocito, Laura, Stiles, Linsey, Zhou, Zhiqiang, Gutierrez, Vincent, Sander, Maike, Shirihai, Orian S., Liesa, Marc

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Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells von Wortham, Matthew, Jin, Genglin, Sun, Julia Lailai, Bigner, Darell D, He, Yiping, Yan, Hai

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Chromatin accessibility mapping identifies mediators of basal transcription and retinoid-induced repression of OTX2 in medulloblastoma von Wortham, Matthew, Guo, Changcun, Zhang, Monica, Song, Lingyun, Lee, Bum-Kyu, Iyer, Vishwanath R, Furey, Terrence S, Crawford, Gregory E, Yan, Hai, He, Yiping

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High T Gives β Cells a Boost von Wortham, Matthew, Sander, Maike

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Mechanisms of β-cell functional adaptation to changes in workload von Wortham, M., Sander, M.

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Sizing up beta cells made from stem cells von Nguyen-Ngoc, Kim-Vy, Wortham, Matthew, Sander, Maike

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Endoplasmic reticulum tubules limit the size of misfolded protein condensates von Parashar, Smriti, Chidambaram, Ravi, Chen, Shuliang, Liem, Christina R., Griffis, Eric, Lambert, Gerard G., Shaner, Nathan C., Wortham, Matthew, Hay, Jesse C., Ferro-Novick, Susan

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Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1β is associated with changes in expression of beta-cell maturity genes and associated histone modifica... von Ibarra Urizar, Adriana, Prause, Michala, Wortham, Matthew, Sui, Yinghui, Thams, Peter, Sander, Maike, Christensen, Gitte Lund, Billestrup, Nils

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Apples to origins: identifying brain tumor stem cell genes by comparing transcriptomes of normal and cancer stem cells von Wortham, Matthew, Yan, Hai

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