The Role of Histone H3-K27M Mutation in Preleukemic HSC Expansion von Dakik, Hassan, Boileau, Meaghan, Worme, Samantha, Jessa, Selin, Iasenza, Isabella, Neumann, Andrea, Sun, Yi Ling, Saby, Manon, Craig, Morgan, Kleinman, Claudia L, Eppert, Kolja

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Single Cell Transcriptomic Analysis of the Histone H3 K27M Mutation in Pre-Leukemic Hematopoietic Stem Cells von Boileau, Meaghan, Jessa, Selin, Worme, Samantha, Faury, Damien, Jabado, Nada, Mercier, François, Kleinman, Claudia, Eppert, Kolja

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K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas von Jessa, Selin, Mohammadnia, Abdulshakour, Harutyunyan, Ashot S., Hulswit, Maud, Varadharajan, Srinidhi, Lakkis, Hussein, Kabir, Nisha, Bashardanesh, Zahedeh, Hébert, Steven, Faury, Damien, Vladoiu, Maria C., Worme, Samantha, Coutelier, Marie, Krug, Brian, Faria Andrade, Augusto, Pathania, Manav, Bajic, Andrea, Weil, Alexander G., Ellezam, Benjamin, Atkinson, Jeffrey, Dudley, Roy W. R., Farmer, Jean-Pierre, Perreault, Sebastien, Garcia, Benjamin A., Larouche, Valérie, Blanchette, Mathieu, Garzia, Livia, Bhaduri, Aparna, Ligon, Keith L., Bandopadhayay, Pratiti, Taylor, Michael D., Mack, Stephen C., Jabado, Nada, Kleinman, Claudia L.

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Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration von Khazaei, Sima, Chen, Carol C.L., Andrade, Augusto Faria, Kabir, Nisha, Azarafshar, Pariya, Morcos, Shahir M., França, Josiane Alves, Lopes, Mariana, Lund, Peder J., Danieau, Geoffroy, Worme, Samantha, Adnani, Lata, Nzirorera, Nadine, Chen, Xiao, Yogarajah, Gayathri, Russo, Caterina, Zeinieh, Michele, Wong, Cassandra J., Bryant, Laura, Hébert, Steven, Tong, Bethany, Sihota, Tianna S., Faury, Damien, Puligandla, Evan, Jawhar, Wajih, Sandy, Veronica, Cowan, Mitra, Nakada, Emily M., Jerome-Majewska, Loydie A., Ellezam, Benjamin, Gomes, Carolina Cavalieri, Denecke, Jonas, Lessel, Davor, McDonald, Marie T., Pizoli, Carolyn E., Taylor, Kathryn, Cocanougher, Benjamin T., Bhoj, Elizabeth J., Gingras, Anne-Claude, Garcia, Benjamin A., Lu, Chao, Campos, Eric I., Kleinman, Claudia L., Garzia, Livia, Jabado, Nada

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The Deubiquitylase Otub1 Regulates the Chemotactic Response of Splenic B Cells by Modulating the Stability of the γ-Subunit Gng2 von Luo, Vincent M, Shen, Connie, Worme, Samantha, Bhagrath, Aanya, Simo-Cheyou, Estelle, Findlay, Steven, Hébert, Steven, Wai Lam Poon, William, Aryanpour, Zahra, Zhang, Thomas, Zahedi, René P, Boulais, Jonathan, Buchwald, Zachary S, Borchers, Christoph H, Côté, Jean-Francois, Kleinman, Claudia L, Mandl, Judith N, Orthwein, Alexandre

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Single-Cell Transcriptomic Profiling of De Novo and Relapsed Acute Myeloid Leukemia Identifies a Leukemic Stemness Program Shared across Diverse Phenotypes von Worme, Samantha, Jessa, Selin, Poon, William, Jankovic, Maja, Vazquez, Gabriela Galicia, Bazinet, Alexandre, Fooks, Katharine, Iasenza, Isabella, Arreba-Tutusaus, Patricia, Eppert, Kolja, Ragoussis, Ioannis, Wang, Yu Chang, Johnson, Nathalie A, Assouline, Sarit E, Kleinman, Claudia L, Mercier, François E

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Early rhombic lip Protogenin+ve stem cells in a human-specific neurovascular niche initiate and maintain group 3 medulloblastoma von Visvanathan, Abhirami, Saulnier, Olivier, Chen, Chuan, Haldipur, Parthiv, Orisme, Wilda, Delaidelli, Alberto, Shin, Seungmin, Millman, Jake, Bryant, Andrew, Abeysundara, Namal, Wu, Xujia, Hendrikse, Liam D., Patil, Vikas, Bashardanesh, Zahedeh, Golser, Joseph, Livingston, Bryn G., Nakashima, Takuma, Funakoshi, Yusuke, Ong, Winnie, Rasnitsyn, Alexandra, Aldinger, Kimberly A., Richman, Cory M., Van Ommeren, Randy, Lee, John J.Y., Ly, Michelle, Vladoiu, Maria C., Kharas, Kaitlin, Balin, Polina, Erickson, Anders W., Fong, Vernon, Zhang, Jiao, Suárez, Raúl A., Wang, Hao, Huang, Ning, Pallota, Jonelle G., Douglas, Tajana, Haapasalo, Joonas, Razavi, Ferechte, Silvestri, Evelina, Sirbu, Olga, Worme, Samantha, Kameda-Smith, Michelle M., Wu, Xiaochong, Daniels, Craig, MichaelRaj, Antony K., Bhaduri, Aparna, Schramek, Daniel, Suzuki, Hiromichi, Garzia, Livia, Ahmed, Nabil, Kleinman, Claudia L., Stein, Lincoln D., Dirks, Peter, Dunham, Christopher, Jabado, Nada, Rich, Jeremy N., Li, Wei, Sorensen, Poul H., Wechsler-Reya, Robert J., Weiss, William A., Millen, Kathleen J., Ellison, David W., Dimitrov, Dimiter S., Taylor, Michael D.

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Common clonal origin of chronic myelomonocytic leukemia and B-cell acute lymphoblastic leukemia in a patient with a germline CHEK2 variant von Bazinet, Alexandre, Heath, John, Chong, Anne-Sophie, Simo-Cheyou, Estelle R, Worme, Samantha, Rivera Polo, Barbara, Foulkes, William D, Caplan, Stephen, Johnson, Nathalie A, Orthwein, Alexandre, Mercier, François E

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Common clonal origin of chronic myelomonocytic leukemia and B-cell acute lymphoblastic leukemia in a patient with a germline CHEK2 variant von Bazinet, Alexandre, Heath, John, Chong, Anne-Sophie, Simo-Cheyou, Estelle R, Worme, Samantha, Rivera, Barbara, Foulkes, William D, Caplan, Stephen, Johnson, Nathalie A, Orthwein, Alexandre, Mercier, François E

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