Hematopoietic stem/progenitor cell commitment to the megakaryocyte lineage von Woolthuis, Carolien M., Park, Christopher Y.

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Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche von Ye, Haobin, Adane, Biniam, Khan, Nabilah, Sullivan, Timothy, Minhajuddin, Mohammad, Gasparetto, Maura, Stevens, Brett, Pei, Shanshan, Balys, Marlene, Ashton, John M., Klemm, Dwight J., Woolthuis, Carolien M., Stranahan, Alec W., Park, Christopher Y., Jordan, Craig T.

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Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones von de Boer, Bauke, Prick, Janine, Pruis, Maurien G., Keane, Peter, Imperato, Maria Rosaria, Jaques, Jennifer, Brouwers-Vos, Annet Z., Hogeling, Shanna M., Woolthuis, Carolien M., Nijk, Marije T., Diepstra, Arjan, Wandinger, Sebastian, Versele, Matthias, Attar, Ricardo M., Cockerill, Peter N., Huls, Gerwin, Vellenga, Edo, Mulder, André B., Bonifer, Constanze, Schuringa, Jan Jacob

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Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms von Spevak, Christina C., Elias, Harold K., Kannan, Lavanya, Ali, Mohamed A.E., Martin, Gaëlle H., Selvaraj, Shanmugapriya, Eng, William S., Ernlund, Amanda, Rajasekhar, Vinagolu K., Woolthuis, Carolien M., Zhao, Guangjie, Ha, Caryn J., Schneider, Robert J., Park, Christopher Y.

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Aging of hematopoietic stem cells: Intrinsic changes or micro-environmental effects? von Woolthuis, Carolien M, de Haan, Gerald, Huls, Gerwin

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CD97 is a critical regulator of acute myeloid leukemia stem cell function von Martin, Gaëlle H, Roy, Nainita, Chakraborty, Sohini, Desrichard, Alexis, Chung, Stephen S, Woolthuis, Carolien M, Hu, Wenhuo, Berezniuk, Iryna, Garrett-Bakelman, Francine E, Hamann, Jörg, Devlin, Sean M, Chan, Timothy A, Park, Christopher Y

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A single center analysis of nucleophosmin in acute myeloid leukemia: value of combining immunohistochemistry with molecular mutation analysis von Woolthuis, Carolien M, Mulder, André B, Verkaik-Schakel, Rikst Nynke, Rosati, Stefano, Diepstra, Arjan, van den Berg, Eva, Schuringa, Jan Jacob, Vellenga, Edo, Kluin, Philip M, Huls, Gerwin

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Histone acetyltransferase activity of MOF is required for adult but not early fetal hematopoiesis in mice von Valerio, Daria G., Xu, Haiming, Eisold, Meghan E., Woolthuis, Carolien M., Pandita, Tej K., Armstrong, Scott A.

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miR-99 regulates normal and malignant hematopoietic stem cell self-renewal von Khalaj, Mona, Woolthuis, Carolien M, Hu, Wenhuo, Durham, Benjamin H, Chu, S Haihua, Qamar, Sarah, Armstrong, Scott A, Park, Christopher Y

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CombiFlow: combinatorial AML-specific plasma membrane expression profiles allow longitudinal tracking of clones von Houtsma, Roos, van der Meer, Nisha K., Meijer, Kees, Morsink, Linde M., Hogeling, Shanna M., Woolthuis, Carolien M., Ammatuna, Emanuele, Nijk, Marije T., de Boer, Bauke, Huls, Gerwin, Mulder, André B., Schuringa, Jan Jacob

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Loss of quiescence and impaired function of CD34(+)/CD38(low) cells one year following autologous stem cell transplantation von Woolthuis, Carolien M, Brouwers-Vos, Annet Z, Huls, Gerwin, de Wolf, Joost Th M, Schuringa, Jan Jacob, Vellenga, Edo

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Loss of quiescence and impaired function of CD34+/CD38low cells one year following autologous stem cell transplantation von Woolthuis, Carolien M., Brouwers-Vos, Annet Z., Huls, Gerwin, de Wolf, Joost Th. M., Schuringa, Jan Jacob, Vellenga, Edo

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Paradoxical down-regulation of p16 mRNA with advancing age in acute myeloid leukemia von de Jonge, Hendrik J M, Woolthuis, Carolien M, de Bont, Eveline S J M, Huls, Gerwin

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AML at older age: age-related gene expression profiles reveal a paradoxical down-regulation of p16INK4A mRNA with prognostic significance von de Jonge, Hendrik J.M., de Bont, Eveline S.J.M., Valk, Peter J.M., Schuringa, Jan Jacob, Kies, Marcel, Woolthuis, Carolien M., Delwel, Ruud, Veeger, Nic J.G.M., Vellenga, Edo, Löwenberg, Bob, Huls, Gerwin

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Aging Impairs Long-Term Hematopoietic Regeneration after Autologous Stem Cell Transplantation von Woolthuis, Carolien M, Mariani, Niccoló, Verkaik-Schakel, Rikst Nynke, Brouwers-Vos, Annet Z, Schuringa, Jan Jacob, Vellenga, Edo, de Wolf, Joost T.M, Huls, Gerwin

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Abstract PR06: Developmentally regulated mTOR degradation in normal and malignant hematopoiesis von Spevak, Christina C., Elias, Harold K., Kannan, Lavanya, Martin, Gaelle, Selvaraj, Shanmugapriya, Eng, William S., Ernlund, Amanda, Rajasekhar, Vinagolu K., Woolthuis, Carolien M., Schneider, Robert J., Park, Christopher Y.

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Unique Regulatory Pathways Dictate the Translational Program in Hematopoietic Stem and Progenitor Cells von Elias, Harold K., Spevak, Christina, Kannan, Lavanya, Ali, Mohamed A.E., Martin, Gaelle H, Selvaraj, Shanmugapriya, Eng, William S, Zhao, Guangjie, Ernlund, Amanda, Rajasekhar, Vinagolu, Woolthuis, Carolien M, Schneider, Robert J, Park, Christopher Y.

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Loss of Stem Cell Quiescence and Impaired Stem Cell Function of CD34+/CD38low Cells One Year Following Autologous Stem Cell Transplantation von Woolthuis, Carolien M, Vos, Annet Z, Huls, Gerwin, de Wolf, Joost TM, Schuringa, Jan J., Vellenga, Edo

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Gene Expression Profiling In Leukemic Stem Cell-Enriched AML CD34+ Cell Fraction Identifies Target Genes That Predict Prognosis In Normal Karyotype AML von Woolthuis, Carolien M, de Jonge, Hendrik JM, Vos, Annet Z, Mulder, Andre B, Berg, Eva van den, Kluin, P.M., van der Weide, Karen, De Bont, Evelina S., Huls, Geert A, Vellenga, Edo, Schuringa, Jan J.

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Autologous Stem Cell Transplantation Induces a Phenotypical Shift From CMP to GMP Progenitors, Reduces Clonogenic Potential and Enhances in Vitro and In Vivo Cycling Activity Defin... von Woolthuis, Carolien M., Agool, Ali, Vos, Annet Z., Slart, Riemert H.J.A., Huls, Geert A., Smid, W. Martin, Schuringa, Jan Jacob, Vellenga, Edo

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