Overcoming MCL-1-driven adaptive resistance to targeted therapies von Wood, Kris C.

Volltext

A p300/GATA6 axis determines differentiation and Wnt dependency in pancreatic cancer models von Zhong, Zheng, Harmston, Nathan, Wood, Kris C, Madan, Babita, Virshup, David M

Volltext

Systematic mapping of BCL-2 gene dependencies in cancer reveals molecular determinants of BH3 mimetic sensitivity von Soderquist, Ryan S., Crawford, Lorin, Liu, Esther, Lu, Min, Agarwal, Anika, Anderson, Gray R., Lin, Kevin H., Winter, Peter S., Cakir, Merve, Wood, Kris C.

Volltext

Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors von Anderson, Gray R., Wardell, Suzanne E., Cakir, Merve, Yip, Catherine, Ahn, Yeong-ran, Ali, Moiez, Yllanes, Alexander P., Chao, Christina A., McDonnell, Donald P., Wood, Kris C.

Volltext

ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer von Park, Sunghee, Chang, Ching-Yi, Safi, Rachid, Liu, Xiaojing, Baldi, Robert, Jasper, Jeff S., Anderson, Grace R., Liu, Tingyu, Rathmell, Jeffrey C., Dewhirst, Mark W., Wood, Kris C., Locasale, Jason W., McDonnell, Donald P.

Volltext

Executioner caspases restrict mitochondrial RNA-driven Type I IFN induction during chemotherapy-induced apoptosis von Killarney, Shane T., Washart, Rachel, Soderquist, Ryan S., Hoj, Jacob P., Lebhar, Jamie, Lin, Kevin H., Wood, Kris C.

Volltext

Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers von Misale, Sandra, Bozic, Ivana, Tong, Jingshan, Peraza-Penton, Ashley, Lallo, Alice, Baldi, Federica, Lin, Kevin H., Truini, Mauro, Trusolino, Livio, Bertotti, Andrea, Di Nicolantonio, Federica, Nowak, Martin A., Zhang, Lin, Wood, Kris C., Bardelli, Alberto

Volltext

Hyperactivation of oncogenic driver pathways as a precision therapeutic strategy von Wood, Kris C.

Volltext

Uncovering scaling laws to infer multidrug response of resistant microbes and cancer cells von Wood, Kevin B, Wood, Kris C, Nishida, Satoshi, Cluzel, Philippe

Volltext

Drivers of intrinsic resistance von Wood, Kris C.

Volltext

Codon bias imposes a targetable limitation on KRAS-driven therapeutic resistance von Ali, Moiez, Kaltenbrun, Erin, Anderson, Gray R., Stephens, Sarah Jo, Arena, Sabrina, Bardelli, Alberto, Counter, Christopher M., Wood, Kris C.

Volltext

Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence von Singleton, Katherine R., Crawford, Lorin, Tsui, Elizabeth, Manchester, Haley E., Maertens, Ophelia, Liu, Xiaojing, Liberti, Maria V., Magpusao, Anniefer N., Stein, Elizabeth M., Tingley, Jennifer P., Frederick, Dennie T., Boland, Genevieve M., Flaherty, Keith T., McCall, Shannon J., Krepler, Clemens, Sproesser, Katrin, Herlyn, Meenhard, Adams, Drew J., Locasale, Jason W., Cichowski, Karen, Mukherjee, Sayan, Wood, Kris C.

Volltext

RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis von Winter, Peter S, Sarosiek, Kristopher A, Lin, Kevin H, Meggendorfer, Manja, Schnittger, Susanne, Letai, Anthony, Wood, Kris C

Volltext

A Landscape of Therapeutic Cooperativity in KRAS Mutant Cancers Reveals Principles for Controlling Tumor Evolution von Anderson, Grace R., Winter, Peter S., Lin, Kevin H., Nussbaum, Daniel P., Cakir, Merve, Stein, Elizabeth M., Soderquist, Ryan S., Crawford, Lorin, Leeds, Jim C., Newcomb, Rachel, Stepp, Priya, Yip, Catherine, Wardell, Suzanne E., Tingley, Jennifer P., Ali, Moiez, Xu, Mengmeng, Ryan, Meagan, McCall, Shannon J., McRee, Autumn J., Counter, Christopher M., Der, Channing J., Wood, Kris C.

Volltext

Controlling Interlayer Diffusion to Achieve Sustained, Multiagent Delivery from Layer-by-Layer Thin Films von Wood, Kris C., Chuang, Helen F., Batten, Robert D., Lynn, David M., Hammond, Paula T.

Volltext

Mapping the Pathways of Resistance to Targeted Therapies von Wood, Kris C

Volltext

Synthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancers von Ding, Yi, Gong, Chang, Huang, De, Chen, Rui, Sui, Pinpin, Lin, Kevin H., Liang, Gehao, Yuan, Lifeng, Xiang, Handan, Chen, Junying, Yin, Tao, Alexander, Peter B., Wang, Qian-Fei, Song, Er-Wei, Li, Qi-Jing, Wood, Kris C., Wang, Xiao-Fan

Volltext

Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection von Price, Alexander M, Dai, Joanne, Bazot, Quentin, Patel, Luv, Nikitin, Pavel A, Djavadian, Reza, Winter, Peter S, Salinas, Cristina A, Barry, Ashley Perkins, Wood, Kris C, Johannsen, Eric C, Letai, Anthony, Allday, Martin J, Luftig, Micah A

Volltext

Electroactive Controlled Release Thin Films von Wood, Kris C., Zacharia, Nicole S., Schmidt, Daniel J., Wrightman, Stefani N., Andaya, Brian J., Hammond, Paula T.

Volltext

A high throughput proliferation and cytotoxicity assay for co-cultured isogenic cell lines von Ahmad, Syed, Wood, Kris C., Scott, John E.

Volltext