Using human genetics to understand the disease impacts of testosterone in men and women von Ruth, Katherine S, Day, Felix R, Tyrrell, Jessica, Thompson, Deborah J, Wood, Andrew R, Mahajan, Anubha, Beaumont, Robin N, Wittemans, Laura, Martin, Susan, Busch, Alexander S., Erzurumluoglu, A. Mesut, Hollis, Benjamin, O’Mara, Tracy A., McCarthy, Mark I, Langenberg, Claudia, Easton, Douglas F, Wareham, Nicholas J, Burgess, Stephen, Murray, Anna, Ong, Ken K, Frayling, Timothy M, Perry, John R. B.

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Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms von Jones, Samuel E., Lane, Jacqueline M., Wood, Andrew R., van Hees, Vincent T., Tyrrell, Jessica, Beaumont, Robin N., Jeffries, Aaron R., Dashti, Hassan S., Hillsdon, Melvyn, Ruth, Katherine S., Tuke, Marcus A., Yaghootkar, Hanieh, Sharp, Seth A., Jie, Yingjie, Thompson, William D., Harrison, Jamie W., Dawes, Amy, Byrne, Enda M., Tiemeier, Henning, Allebrandt, Karla V., Bowden, Jack, Ray, David W., Freathy, Rachel M., Murray, Anna, Mazzotti, Diego R., Gehrman, Philip R., Lawlor, Debbie A., Frayling, Timothy M., Rutter, Martin K., Hinds, David A., Saxena, Richa, Weedon, Michael N.

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Genetic predictors of participation in optional components of UK Biobank von Tyrrell, Jessica, Zheng, Jie, Beaumont, Robin, Hinton, Kathryn, Richardson, Tom G., Wood, Andrew R., Davey Smith, George, Frayling, Timothy M., Tilling, Kate

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Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis von Sharp, Seth A, Rich, Stephen S, Wood, Andrew R, Jones, Samuel E, Beaumont, Robin N, Harrison, James W, Schneider, Darius A, Locke, Jonathan M, Tyrrell, Jess, Weedon, Michael N, Hagopian, William A, Oram, Richard A

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Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting von Wright, Caroline F., West, Ben, Tuke, Marcus, Jones, Samuel E., Patel, Kashyap, Laver, Thomas W., Beaumont, Robin N., Tyrrell, Jessica, Wood, Andrew R., Frayling, Timothy M., Hattersley, Andrew T., Weedon, Michael N.

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Biological interpretation of genome-wide association studies using predicted gene functions von Pers, Tune H., Karjalainen, Juha M., Chan, Yingleong, Westra, Harm-Jan, Wood, Andrew R., Yang, Jian, Lui, Julian C., Vedantam, Sailaja, Gustafsson, Stefan, Esko, Tonu, Frayling, Tim, Speliotes, Elizabeth K., Boehnke, Michael, Raychaudhuri, Soumya, Fehrmann, Rudolf S. N., Hirschhorn, Joel N., Franke, Lude

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Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes von Wang, Heming, Lane, Jacqueline M., Jones, Samuel E., Dashti, Hassan S., Ollila, Hanna M., Wood, Andrew R., van Hees, Vincent T., Brumpton, Ben, Winsvold, Bendik S., Kantojärvi, Katri, Palviainen, Teemu, Cade, Brian E., Sofer, Tamar, Song, Yanwei, Patel, Krunal, Anderson, Simon G., Bechtold, David A., Bowden, Jack, Emsley, Richard, Kyle, Simon D., Little, Max A., Loudon, Andrew S., Scheer, Frank A. J. L., Purcell, Shaun M., Richmond, Rebecca C., Spiegelhalder, Kai, Tyrrell, Jessica, Zhu, Xiaofeng, Hublin, Christer, Kaprio, Jaakko A., Kristiansson, Kati, Sulkava, Sonja, Paunio, Tiina, Hveem, Kristian, Nielsen, Jonas B., Willer, Cristen J., Zwart, John-Anker, Strand, Linn B., Frayling, Timothy M., Ray, David, Lawlor, Deborah A., Rutter, Martin K., Weedon, Michael N., Redline, Susan, Saxena, Richa

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Quantification of the overall contribution of gene-environment interaction for obesity-related traits von Sulc, Jonathan, Mounier, Ninon, Günther, Felix, Winkler, Thomas, Wood, Andrew R., Frayling, Timothy M., Heid, Iris M., Robinson, Matthew R., Kutalik, Zoltán

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Higher adiposity and mental health: causal inference using Mendelian randomization von Casanova, Francesco, O’Loughlin, Jessica, Martin, Susan, Beaumont, Robin N, Wood, Andrew R, Watkins, Edward R, Freathy, Rachel M, Hagenaars, Saskia P, Frayling, Timothy M, Yaghootkar, Hanieh, Tyrrell, Jess

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Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome von Porcu, Eleonora, Sadler, Marie C., Lepik, Kaido, Auwerx, Chiara, Wood, Andrew R., Weihs, Antoine, Sleiman, Maroun S. Bou, Ribeiro, Diogo M., Bandinelli, Stefania, Tanaka, Toshiko, Nauck, Matthias, Völker, Uwe, Delaneau, Olivier, Metspalu, Andres, Teumer, Alexander, Frayling, Timothy, Santoni, Federico A., Reymond, Alexandre, Kutalik, Zoltán

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Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study von Casanova, Francesco, O'Loughlin, Jessica, Karageorgiou, Vasilis, Beaumont, Robin N, Bowden, Jack, Wood, Andrew R, Tyrrell, Jessica

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Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis von Thompson, William D, Tyrrell, Jessica, Borges, Maria-Carolina, Beaumont, Robin N, Knight, Bridget A, Wood, Andrew R, Ring, Susan M, Hattersley, Andrew T, Freathy, Rachel M, Lawlor, Debbie A

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A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor von Green, Harry D., Jones, Alistair, Evans, Jonathan P., Wood, Andrew R., Beaumont, Robin N., Tyrrell, Jessica, Frayling, Timothy M., Smith, Christopher, Weedon, Michael N.

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Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing von Harries, Lorna W., Hernandez, Dena, Henley, William, Wood, Andrew R., Holly, Alice C., Bradley‐Smith, Rachel M., Yaghootkar, Hanieh, Dutta, Ambarish, Murray, Anna, Frayling, Timothy M., Guralnik, Jack M., Bandinelli, Stefania, Singleton, Andrew, Ferrucci, Luigi, Melzer, David

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Identification and analysis of individuals who deviate from their genetically-predicted phenotype von Hawkes, Gareth, Yengo, Loic, Vedantam, Sailaja, Marouli, Eirini, Beaumont, Robin N, Tyrrell, Jessica, Weedon, Michael N, Hirschhorn, Joel, Frayling, Timothy M, Wood, Andrew R

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Cell Specific eQTL Analysis without Sorting Cells von Westra, Harm-Jan, Arends, Danny, Esko, Tõnu, Peters, Marjolein J, Schurmann, Claudia, Schramm, Katharina, Kettunen, Johannes, Yaghootkar, Hanieh, Fairfax, Benjamin P, Andiappan, Anand Kumar, Li, Yang, Fu, Jingyuan, Karjalainen, Juha, Platteel, Mathieu, Visschedijk, Marijn, Weersma, Rinse K, Kasela, Silva, Milani, Lili, Tserel, Liina, Peterson, Pärt, Reinmaa, Eva, Hofman, Albert, Uitterlinden, André G, Rivadeneira, Fernando, Homuth, Georg, Petersmann, Astrid, Lorbeer, Roberto, Prokisch, Holger, Meitinger, Thomas, Herder, Christian, Roden, Michael, Grallert, Harald, Ripatti, Samuli, Perola, Markus, Wood, Andrew R, Melzer, David, Ferrucci, Luigi, Singleton, Andrew B, Hernandez, Dena G, Knight, Julian C, Melchiotti, Rossella, Lee, Bernett, Poidinger, Michael, Zolezzi, Francesca, Larbi, Anis, Wang, De Yun, van den Berg, Leonard H, Veldink, Jan H, Rotzschke, Olaf, Makino, Seiko, Salomaa, Veikko, Strauch, Konstantin, Völker, Uwe, van Meurs, Joyce B J, Metspalu, Andres, Wijmenga, Cisca, Jansen, Ritsert C, Franke, Lude

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Detection and characterization of male sex chromosome abnormalities in the UK Biobank study von Zhao, Yajie, Gardner, Eugene J, Tuke, Marcus A, Zhang, Huairen, Pietzner, Maik, Koprulu, Mine, Jia, Raina Y, Ruth, Katherine S, Wood, Andrew R, Beaumont, Robin N, Tyrrell, Jessica, Jones, Samuel E, Lango Allen, Hana, Day, Felix R, Langenberg, Claudia, Frayling, Timothy M, Weedon, Michael N, Perry, John R B, Ong, Ken K, Murray, Anna

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Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based i... von Wood, Andrew R, Perry, John R B, Tanaka, Toshiko, Hernandez, Dena G, Zheng, Hou-Feng, Melzer, David, Gibbs, J Raphael, Nalls, Michael A, Weedon, Michael N, Spector, Tim D, Richards, J Brent, Bandinelli, Stefania, Ferrucci, Luigi, Singleton, Andrew B, Frayling, Timothy M

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Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers von Pilling, Luke C, Atkins, Janice L, Duff, Michael O, Beaumont, Robin N, Jones, Samuel E, Tyrrell, Jessica, Kuo, Chia-Ling, Ruth, Katherine S, Tuke, Marcus A, Yaghootkar, Hanieh, Wood, Andrew R, Murray, Anna, Weedon, Michael N, Harries, Lorna W, Kuchel, George A, Ferrucci, Luigi, Frayling, Timothy M, Melzer, David

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Common maternal and fetal genetic variants show expected polygenic effects on risk of small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies von Beaumont, Robin N., Kotecha, Sarah J., Wood, Andrew R., Knight, Bridget A., Sebert, Sylvain, McCarthy, Mark, Hattersley, Andrew T., Jarvelin, Marjo-Riitta, Timpson, Nicholas J., Freathy, Rachel M., Kotecha, Sailesh

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