MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis von Chan, Kui Ming, Wong, Hoi Leong Xavier, Jin, Guoxiang, Liu, Baohua, Cao, Renhai, Cao, Yihai, Lehti, Kaisa, Tryggvason, Karl, Zhou, Zhongjun

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PMI-controlled mannose metabolism and glycosylation determines tissue tolerance and virus fitness von Liang, Ronghui, Ye, Zi-Wei, Qin, Zhenzhi, Xie, Yubin, Yang, Xiaomeng, Sun, Haoran, Du, Qiaohui, Luo, Peng, Tang, Kaiming, Hu, Bodan, Cao, Jianli, Wong, Xavier Hoi-Leong, Ling, Guang-Sheng, Chu, Hin, Shen, Jiangang, Yin, Feifei, Jin, Dong-Yan, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung, Yuan, Shuofeng

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Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling von Wong, Hoi Leong Xavier, Qin, Hong-yan, Tsang, Siu Wai, Zuo, Xiao, Che, Sijia, Chow, Chi Fung Willis, Li, Xi, Xiao, Hai-tao, Zhao, Ling, Huang, Tao, Lin, Cheng Yuan, Kwan, Hiu Yee, Yang, Tao, Longo, Frank M., Lyu, Aiping, Bian, Zhao-xiang

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Enterochromaffin cell hyperplasia in the gut: Factors, mechanism and therapeutic clues von Qin, Hong-yan, Xavier Wong, Hoi Leong, Zang, Kai-hong, Li, Xun, Bian, Zhao-xiang

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Toll-like receptor 4 is a master regulator for colorectal cancer growth under high-fat diet by programming cancer metabolism von Hu, Xianjing, Fatima, Sarwat, Chen, Minting, Xu, Keyang, Huang, Chunhua, Gong, Rui-Hong, Su, Tao, Wong, Hoi Leong Xavier, Bian, Zhaoxiang, Kwan, Hiu Yee

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Dihydroartemisinin is potential therapeutics for treating late-stage CRC by targeting the elevated c-Myc level von Hu, Xianjing, Fatima, Sarwat, Chen, Minting, Huang, Tao, Chen, Yuen Wa, Gong, Ruihong, Wong, Hoi Leong Xavier, Yu, Rongmin, Song, Liyan, Kwan, Hiu Yee, Bian, Zhaoxiang

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Palmitic acid is an intracellular signaling molecule involved in disease development von Fatima, Sarwat, Hu, Xianjing, Gong, Rui-Hong, Huang, Chunhua, Chen, Minting, Wong, Hoi Leong Xavier, Bian, Zhaoxiang, Kwan, Hiu Yee

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Gut-Microbial Metabolites, Probiotics and Their Roles in Type 2 Diabetes von Zhai, Lixiang, Wu, Jiayan, Lam, Yan Y., Kwan, Hiu Yee, Bian, Zhao-Xiang, Wong, Hoi Leong Xavier

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Exploring the mechanism of Suxin Hugan Fang in treating ulcerative colitis based on network pharmacology von Huang, Qiang, Peng, Weijie, Luo, Qing, Zhao, Wenchang, Dai, Weibo, Zeng, Huifen, Wong, Hoi Leong Xavier, Hu, Xianjing

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Gut microbiota-derived tryptamine and phenethylamine impair insulin sensitivity in metabolic syndrome and irritable bowel syndrome von Zhai, Lixiang, Xiao, Haitao, Lin, Chengyuan, Wong, Hoi Leong Xavier, Lam, Yan Y., Gong, Mengxue, Wu, Guojun, Ning, Ziwan, Huang, Chunhua, Zhang, Yijing, Yang, Chao, Luo, Jingyuan, Zhang, Lu, Zhao, Ling, Zhang, Chenhong, Lau, Johnson Yiu-Nam, Lu, Aiping, Lau, Lok-Ting, Jia, Wei, Zhao, Liping, Bian, Zhao-Xiang

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Regulation of age-associated insulin resistance by MT1-MMP-mediated cleavage of insulin receptor von Guo, Xuanming, Asthana, Pallavi, Gurung, Susma, Zhang, Shuo, Wong, Sheung Kin Ken, Fallah, Samane, Chow, Chi Fung Willis, Che, Sijia, Zhai, Lixiang, Wang, Zening, Ge, Xin, Jiang, Zhixin, Wu, Jiayan, Zhang, Yijing, Wu, Xiaoyu, Xu, Keyang, Lin, Cheng Yuan, Kwan, Hiu Yee, Lyu, Aiping, Zhou, Zhongjun, Bian, Zhao-Xiang, Wong, Hoi Leong Xavier

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MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis von Wong, Hoi Leong Xavier, Jin, Guoxiang, Cao, Renhai, Zhang, Shuo, Cao, Yihai, Zhou, Zhongjun

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Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2 von Guo, Xuanming, Cao, Jianli, Cai, Jian-Piao, Wu, Jiayan, Huang, Jiangang, Asthana, Pallavi, Wong, Sheung Kin Ken, Ye, Zi-Wei, Gurung, Susma, Zhang, Yijing, Wang, Sheng, Wang, Zening, Ge, Xin, Kwan, Hiu Yee, Lyu, Aiping, Chan, Kui Ming, Wong, Nathalie, Huang, Jiandong, Zhou, Zhongjun, Bian, Zhao-Xiang, Yuan, Shuofeng, Wong, Hoi Leong Xavier

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Saturated long-chain fatty acid-producing bacteria contribute to enhanced colonic motility in rats von Zhao, Ling, Huang, Yufen, Lu, Lin, Yang, Wei, Huang, Tao, Lin, Zesi, Lin, Chengyuan, Kwan, Hiuyee, Wong, Hoi Leong Xavier, Chen, Yang, Sun, Silong, Xie, Xuefeng, Fang, Xiaodong, Yang, Huanming, Wang, Jian, Zhu, Lixin, Bian, Zhaoxiang

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Artesunate treats obesity in male mice and non-human primates through GDF15/GFRAL signalling axis von Guo, Xuanming, Asthana, Pallavi, Zhai, Lixiang, Cheng, Ka Wing, Gurung, Susma, Huang, Jiangang, Wu, Jiayan, Zhang, Yijing, Mahato, Arun Kumar, Saarma, Mart, Ustav, Mart, Kwan, Hiu Yee, Lyu, Aiping, Chan, Kui Ming, Xu, Pingyi, Bian, Zhao-Xiang, Wong, Hoi Leong Xavier

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High-fat diet feeding and palmitic acid increase CRC growth in β2AR-dependent manner von Fatima, Sarwat, Hu, Xianjing, Huang, Chunhua, Zhang, Weixiong, Cai, Jing, Huang, Min, Gong, Rui-Hong, Chen, Minting, Ho, Alan H. M., Su, Tao, Wong, Hoi Leong Xavier, Bian, Zhaoxiang, Kwan, Hiu Yee

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Combination of artesunate and WNT974 induces KRAS protein degradation by upregulating E3 ligase ANACP2 and β-TrCP in the ubiquitin-proteasome pathway von Gong, Rui-Hong, Chen, Minting, Huang, Chunhua, Wong, Hoi Leong Xavier, Kwan, Hiu Yee, Bian, Zhaoxiang

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IDDF2022-ABS-0035 Pathogenetic role of GUT microbiota shunting of dietary phenylalanine to phenethylamine in diarrhea-predominant irritable bowel syndrome von Zhai, Lixiang, Huang, Chunhua, Ning, Ziwan, Zhang, Yijing, Zhuang, Min, Yang, Wei, Wang, Xiaolei, Wang, Jingjing, Zhang, Eric Lu, Xiao, Haitao, Zhao, Ling, Lam, Yan Y, Willis Chow, Chi-Fung, Huang, Jiandong, Yuan, Shuofeng, Chan, Kui-Ming, Yuan, Chun-Su, Lau, Johnson Yiu-Nam, Xavier Wong, Hoi-Leong, Bian, Zhao-Xiang

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Baicalein is a novel TLR4‐targeting therapeutics agent that inhibits TLR4/HIF‐1α/VEGF signaling pathway in colorectal cancer von Chen, Minting, Zhong, Keying, Tan, Jincheng, Meng, Mingjing, Liu, Chok Mei, Chen, Baisen, Huang, Chunhua, Wong, Hoi Leong Xavier, Bian, Zhaoxiang, Su, Tao, Kwan, Hiu Yee

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Berberine Suppresses Colonic Inflammation in Dextran Sulfate Sodium-Induced Murine Colitis Through Inhibition of Cytosolic Phospholipase A2 Activity von Zhai, Lixiang, Huang, Tao, Xiao, Hai-tao, Wu, Pei-gen, Lin, Cheng-yuan, Ning, Zi-wan, Zhao, Ling, Kwan, Hiu Yee Anna, Hu, Xian-jing, Wong, Hoi Leong Xavier, Li, Xian-qian, Bian, Zhao-xiang

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