PD-1 and PD-L1 Expression in NSCLC Indicate a Favorable Prognosis in Defined Subgroups von Schmidt, Lars Henning, Kümmel, Andreas, Görlich, Dennis, Mohr, Michael, Bröckling, Sebastian, Mikesch, Jan Henrik, Grünewald, Inga, Marra, Alessandro, Schultheis, Anne M, Wardelmann, Eva, Müller-Tidow, Carsten, Spieker, Tilmann, Schliemann, Christoph, Berdel, Wolfgang E, Wiewrodt, Rainer, Hartmann, Wolfgang

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RNA-Guided CRISPR-Cas9 System-Mediated Engineering of Acute Myeloid Leukemia Mutations von Brabetz, Oliver, Alla, Vijay, Angenendt, Linus, Schliemann, Christoph, Berdel, Wolfgang E., Arteaga, Maria-Francisca, Mikesch, Jan-Henrik

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Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia von Metzeler, Klaus H., Herold, Tobias, Rothenberg-Thurley, Maja, Amler, Susanne, Sauerland, Maria C., Görlich, Dennis, Schneider, Stephanie, Konstandin, Nikola P., Dufour, Annika, Bräundl, Kathrin, Ksienzyk, Bianka, Zellmeier, Evelyn, Hartmann, Luise, Greif, Philipp A., Fiegl, Michael, Subklewe, Marion, Bohlander, Stefan K., Krug, Utz, Faldum, Andreas, Berdel, Wolfgang E., Wörmann, Bernhard, Büchner, Thomas, Hiddemann, Wolfgang, Braess, Jan, Spiekermann, Karsten

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Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia von Herold, Tobias, Rothenberg-Thurley, Maja, Grunwald, Victoria V., Janke, Hanna, Goerlich, Dennis, Sauerland, Maria C., Konstandin, Nikola P., Dufour, Annika, Schneider, Stephanie, Neusser, Michaela, Ksienzyk, Bianka, Greif, Philipp A., Subklewe, Marion, Faldum, Andreas, Bohlander, Stefan K., Braess, Jan, Wörmann, Bernhard, Krug, Utz, Berdel, Wolfgang E., Hiddemann, Wolfgang, Spiekermann, Karsten, Metzeler, Klaus H.

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The Long Noncoding MALAT-1 RNA Indicates a Poor Prognosis in Non-small Cell Lung Cancer and Induces Migration and Tumor Growth von Schmidt, Lars Henning, Spieker, Tilmann, Koschmieder, Steffen, Humberg, Julia, Jungen, Dominik, Bulk, Etmar, Hascher, Antje, Wittmer, Danielle, Marra, Alessandro, Hillejan, Ludger, Wiebe, Karsten, Berdel, Wolfgang E., Wiewrodt, Rainer, Muller-Tidow, Carsten

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Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia von Göllner, Stefanie, Oellerich, Thomas, Agrawal-Singh, Shuchi, Schenk, Tino, Klein, Hans-Ulrich, Rohde, Christian, Pabst, Caroline, Sauer, Tim, Lerdrup, Mads, Tavor, Sigal, Stölzel, Friedrich, Herold, Sylvia, Ehninger, Gerhard, Köhler, Gabriele, Pan, Kuan-Ting, Urlaub, Henning, Serve, Hubert, Dugas, Martin, Spiekermann, Karsten, Vick, Binje, Jeremias, Irmela, Berdel, Wolfgang E, Hansen, Klaus, Zelent, Arthur, Wickenhauser, Claudia, Müller, Lutz P, Thiede, Christian, Müller-Tidow, Carsten

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Genetics of acute myeloid leukemia in the elderly: mutation spectrum and clinical impact in intensively treated patients aged 75 years or older von Prassek, Victoria V, Rothenberg-Thurley, Maja, Sauerland, Maria C, Herold, Tobias, Janke, Hanna, Ksienzyk, Bianka, Konstandin, Nikola P, Goerlich, Dennis, Krug, Utz, Faldum, Andreas, Berdel, Wolfgang E, Wörmann, Bernhard, Braess, Jan, Schneider, Stephanie, Subklewe, Marion, Bohlander, Stefan K, Hiddemann, Wolfgang, Spiekermann, Karsten, Metzeler, Klaus H

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SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia von Schneider, Constanze, Oellerich, Thomas, Baldauf, Hanna-Mari, Schwarz, Sarah-Marie, Thomas, Dominique, Flick, Robert, Bohnenberger, Hanibal, Kaderali, Lars, Stegmann, Lena, Cremer, Anjali, Martin, Margarethe, Lohmeyer, Julian, Michaelis, Martin, Hornung, Veit, Schliemann, Christoph, Berdel, Wolfgang E, Hartmann, Wolfgang, Wardelmann, Eva, Comoglio, Federico, Hansmann, Martin-Leo, Yakunin, Alexander F, Geisslinger, Gerd, Ströbel, Philipp, Ferreirós, Nerea, Serve, Hubert, Keppler, Oliver T, Cinatl, Jindrich

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Sorafenib in Combination With Intensive Chemotherapy in Elderly Patients With Acute Myeloid Leukemia: Results From a Randomized, Placebo-Controlled Trial von SERVE, Hubert, KRUG, Utz, FISCHER, Thomas, GIAGOUNIDIS, Aristoteles, NEUBAUER, Andreas, REICHLE, Albrecht, AULITZKY, Walter, NOPPENEY, Richard, BLAU, Igor, KUNZMANN, Volker, STUHLMANN, Reingard, KRÄMER, Alwin, WAGNER, Ruth, KREUZER, Karl-Anton, BRANDTS, Christian, STEFFEN, Björn, THIEDE, Christian, MÜLLER-TIDOW, Carsten, EHNINGER, Gerhard, BERDEL, Wolfgang E, SAUERLAND, M. Cristina, HEINECKE, Achim, BRUNNBERG, Uta, SCHAICH, Markus, OTTMANN, Oliver, DUYSTER, Justus, WANDT, Hannes

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Prostate specific membrane antigen (PSMA) expression in non-small cell lung cancer von Schmidt, Lars Henning, Heitkötter, Birthe, Schulze, Arik B, Schliemann, Christoph, Steinestel, Konrad, Trautmann, Marcel, Marra, Alessandro, Hillejan, Ludger, Mohr, Michael, Evers, Georg, Wardelmann, Eva, Rahbar, Kambiz, Görlich, Dennis, Lenz, Georg, Berdel, Wolfgang E, Hartmann, Wolfgang, Wiewrodt, Rainer, Huss, Sebastian

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Antibody-mediated delivery of anti-KRAS-siRNA in vivo overcomes therapy resistance in colon cancer von Bäumer, Sebastian, Bäumer, Nicole, Appel, Neele, Terheyden, Lisa, Fremerey, Julia, Schelhaas, Sonja, Wardelmann, Eva, Buchholz, Frank, Berdel, Wolfgang E, Müller-Tidow, Carsten

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Future Options of Molecular-Targeted Therapy in Small Cell Lung Cancer von Schulze, Arik Bernard, Evers, Georg, Kerkhoff, Andrea, Mohr, Michael, Schliemann, Christoph, Berdel, Wolfgang E, Schmidt, Lars Henning

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Reduced-intensity conditioning versus standard conditioning before allogeneic haemopoietic cell transplantation in patients with acute myeloid leukaemia in first complete remission... von Bornhäuser, Martin, Prof, Kienast, Joachim, Prof, Trenschel, Rudolf, MD, Burchert, Andreas, Prof, Hegenbart, Ute, MD, Stadler, Michael, MD, Baurmann, Herrad, MD, Schäfer-Eckart, Kerstin, MD, Holler, Ernst, Prof, Kröger, Nicolaus, Prof, Schmid, Christoph, MD, Einsele, Herrmann, Prof, Kiehl, Michael G, MD, Hiddemann, Wolfgang, Prof, Schwerdtfeger, Rainer, MD, Buchholz, Stefanie, MD, Dreger, Peter, Prof, Neubauer, Andreas, Prof, Berdel, Wolfgang E, Prof, Ehninger, Gerhard, Prof, Beelen, Dietrich W, Prof, Schetelig, Johannes, MD, Stelljes, Matthias, MD

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A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia von Herold, Tobias, Jurinovic, Vindi, Batcha, Aarif M N, Bamopoulos, Stefanos A, Rothenberg-Thurley, Maja, Ksienzyk, Bianka, Hartmann, Luise, Greif, Philipp A, Phillippou-Massier, Julia, Krebs, Stefan, Blum, Helmut, Amler, Susanne, Schneider, Stephanie, Konstandin, Nikola, Sauerland, Maria Cristina, Görlich, Dennis, Berdel, Wolfgang E, Wörmann, Bernhard J, Tischer, Johanna, Subklewe, Marion, Bohlander, Stefan K, Braess, Jan, Hiddemann, Wolfgang, Metzeler, Klaus H, Mansmann, Ulrich, Spiekermann, Karsten

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An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia von Metzeler, Klaus H., Hummel, Manuela, Bloomfield, Clara D., Spiekermann, Karsten, Braess, Jan, Sauerland, Maria-Cristina, Heinecke, Achim, Radmacher, Michael, Marcucci, Guido, Whitman, Susan P., Maharry, Kati, Paschka, Peter, Larson, Richard A., Berdel, Wolfgang E., Büchner, Thomas, Wörmann, Bernhard, Mansmann, Ulrich, Hiddemann, Wolfgang, Bohlander, Stefan K., Buske, Christian

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Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes von Krug, Utz, Dr, Röllig, Christoph, MD, Koschmieder, Anja, Heinecke, Achim, PhD, Sauerland, Maria Cristina, MSc, Schaich, Markus, Prof, Thiede, Christian, Prof, Kramer, Michael, Braess, Jan, Prof, Spiekermann, Karsten, MD, Haferlach, Torsten, Prof, Haferlach, Claudia, MD, Koschmieder, Steffen, MD, Rohde, Christian, PhD, Serve, Hubert, Prof, Wörmann, Bernhard, Prof, Hiddemann, Wolfgang, Prof, Ehninger, Gerhard, Prof, Berdel, Wolfgang E, Prof, Büchner, Thomas, Prof, Müller-Tidow, Carsten, Prof

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Acute Myeloid Leukemia With Biallelic CEBPA Gene Mutations and Normal Karyotype Represents a Distinct Genetic Entity Associated With a Favorable Clinical Outcome von DUFOUR, Annika, SCHNEIDER, Friederike, WÖRMANN, Bernhard, BRAESS, Jan, HIDDEMANN, Wolfgang, BOHLANDER, Stefan K, SPIEKERMANN, Karsten, METZELER, Klaus H, HOSTER, Eva, SCHNEIDER, Stephanie, ZELLMEIER, Evelyn, BENTHAUS, Tobias, SAUERLAND, Maria-Cristina, BERDEL, Wolfgang E, BÜCHNER, Thomas

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Age-Related Risk Profile and Chemotherapy Dose Response in Acute Myeloid Leukemia: A Study by the German Acute Myeloid Leukemia Cooperative Group von BÜCHNER, Thomas, BERDEL, Wolfgang E, GRIINEISEN, Andreas, KERN, Wolfgang, REICHLE, Albrecht, MASCHMEYER, Georg, AUL, Carlo, LENGFELDER, Eva, SAUERLAND, Maria-Cristina, HEINECKE, Achim, WÖRMANN, Bernhard, HIDDEMANN, Wolfgang, HAFERLACH, Claudia, HAFERLACH, Torsten, SCHNITTGER, Susanne, MÜLLER-TIDOW, Carsten, BRAESS, Jan, SPIEKERMANN, Karsten, KIENAST, Joachim, STAIB, Peter

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Mislocalized Activation of Oncogenic RTKs Switches Downstream Signaling Outcomes von Choudhary, Chunaram, Olsen, Jesper V., Brandts, Christian, Cox, Jürgen, Reddy, Pavankumar N.G., Böhmer, Frank D., Gerke, Volker, Schmidt-Arras, Dirk-E., Berdel, Wolfgang E., Müller-Tidow, Carsten, Mann, Matthias, Serve, Hubert

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Amsacrine-based induction therapy in AML patients with cardiac comorbidities: a retrospective single-center analysis von Kuron, David, Pohlmann, Alexander, Angenendt, Linus, Kessler, Torsten, Mesters, Rolf, Berdel, Wolfgang E., Stelljes, Matthias, Lenz, Georg, Schliemann, Christoph, Mikesch, Jan-Henrik

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