Therapeutic Potential of Oridonin and Its Analogs: From Anticancer and Antiinflammation to Neuroprotection von Xu, Jimin, Wold, Eric A, Ding, Ye, Shen, Qiang, Zhou, Jia

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Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts von Wold, Eric A, Chen, Jianping, Cunningham, Kathryn A, Zhou, Jia

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Drug Discovery Targeting Bromodomain-Containing Protein 4 von Liu, Zhiqing, Wang, Pingyuan, Chen, Haiying, Wold, Eric A, Tian, Bing, Brasier, Allan R, Zhou, Jia

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Discovery and development of natural product oridonin-inspired anticancer agents von Ding, Ye, Ding, Chunyong, Ye, Na, Liu, Zhiqing, Wold, Eric A., Chen, Haiying, Wild, Christopher, Shen, Qiang, Zhou, Jia

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Therapeutic Potential of Spirooxindoles as Antiviral Agents von Ye, Na, Chen, Haiying, Wold, Eric A, Shi, Pei-Yong, Zhou, Jia

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Small Molecules Selectively Targeting Sigma‑1 Receptor for the Treatment of Neurological Diseases von Ye, Na, Qin, Wangzhi, Tian, Sheng, Xu, Qingfeng, Wold, Eric A, Zhou, Jia, Zhen, Xue-Chu

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Small-Molecule Inhibitors Targeting the Canonical WNT Signaling Pathway for the Treatment of Cancer von Liu, Zhiqing, Wang, Pingyuan, Wold, Eric A, Song, Qiaoling, Zhao, Chenyang, Wang, Changyun, Zhou, Jia

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Discovery of Orally Bioavailable Chromone Derivatives as Potent and Selective BRD4 Inhibitors: Scaffold Hopping, Optimization, and Pharmacological Evaluation von Liu, Zhiqing, Chen, Haiying, Wang, Pingyuan, Li, Yi, Wold, Eric A, Leonard, Paul G, Joseph, Sarah, Brasier, Allan R, Tian, Bing, Zhou, Jia

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BH4 domain of Bcl-2 as a novel target for cancer therapy von Liu, Zhiqing, Wild, Christopher, Ding, Ye, Ye, Na, Chen, Haiying, Wold, Eric A., Zhou, Jia

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Discovery, X‑ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site von Liu, Zhiqing, Li, Yi, Chen, Haiying, Lai, Hsien-Tsung, Wang, Pingyuan, Wu, Shwu-Yuan, Wold, Eric A, Leonard, Paul G, Joseph, Sarah, Hu, Haitao, Chiang, Cheng-Ming, Brasier, Allan R, Tian, Bing, Zhou, Jia

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Regio- and Stereospecific Synthesis of Oridonin D‑Ring Aziridinated Analogues for the Treatment of Triple-Negative Breast Cancer via Mediated Irreversible Covalent Warheads von Ding, Ye, Li, Dengfeng, Ding, Chunyong, Wang, Pingyuan, Liu, Zhiqing, Wold, Eric A, Ye, Na, Chen, Haiying, White, Mark A, Shen, Qiang, Zhou, Jia

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Orphan Receptor GPR88 as an Emerging Neurotherapeutic Target von Ye, Na, Li, Bang, Mao, Qi, Wold, Eric A, Tian, Sheng, Allen, John A, Zhou, Jia

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Discovery of a Small Molecule Inhibitor of Human Adenovirus Capable of Preventing Escape from the Endosome von Xu, Jimin, Berastegui-Cabrera, Judith, Carretero-Ledesma, Marta, Chen, Haiying, Xue, Yu, Wold, Eric A., Pachon, Jeronimo, Zhou, Jia, Sanchez-Cespedes, Javier

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Design, Synthesis, and Characterization of 4‑Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5‑HT2C Receptor von Wild, Christopher T, Miszkiel, Joanna M, Wold, Eric A, Soto, Claudia A, Ding, Chunyong, Hartley, Rachel M, White, Mark A, Anastasio, Noelle C, Cunningham, Kathryn A, Zhou, Jia

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Discovery of Novel Oleamide Analogues as Brain-Penetrant Positive Allosteric Serotonin 5‑HT2C Receptor and Dual 5‑HT2C/5-HT2A Receptor Modulators von Chen, Jianping, Garcia, Erik J., Merritt, Christina R., Zamora, Joshua C., Bolinger, Andrew A., Pazdrak, Konrad, Stafford, Susan J., Mifflin, Randy C., Wold, Eric A., Wild, Christopher T., Chen, Haiying, Anastasio, Noelle C., Cunningham, Kathryn A., Zhou, Jia

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Discovery of 4‑Phenylpiperidine-2-Carboxamide Analogues as Serotonin 5‑HT2C Receptor-Positive Allosteric Modulators with Enhanced Drug-like Properties von Wold, Eric A, Garcia, Erik J, Wild, Christopher T, Miszkiel, Joanna M, Soto, Claudia A, Chen, Jianping, Pazdrak, Konrad, Fox, Robert G, Anastasio, Noelle C, Cunningham, Kathryn A, Zhou, Jia

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Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT 2C Receptor von Wild, Christopher T, Miszkiel, Joanna M, Wold, Eric A, Soto, Claudia A, Ding, Chunyong, Hartley, Rachel M, White, Mark A, Anastasio, Noelle C, Cunningham, Kathryn A, Zhou, Jia

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Discovery of Novel Oleamide Analogues as Brain-Penetrant Positive Allosteric Serotonin 5-HT 2C Receptor and Dual 5-HT 2C /5-HT 2A Receptor Modulators von Chen, Jianping, Garcia, Erik J, Merritt, Christina R, Zamora, Joshua C, Bolinger, Andrew A, Pazdrak, Konrad, Stafford, Susan J, Mifflin, Randy C, Wold, Eric A, Wild, Christopher T, Chen, Haiying, Anastasio, Noelle C, Cunningham, Kathryn A, Zhou, Jia

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Structure-activity relationship studies on Bax activator SMBA1 for the treatment of ER-positive and triple-negative breast cancer von Liu, Gang, Yin, Tao, Kim, Hyejin, Ding, Chunyong, Yu, Zhuo, Wang, Hong, Chen, Haiying, Yan, Ruping, Wold, Eric A., Zou, Hao, Liu, Xi, Ding, Ye, Shen, Qiang, Zhou, Jia

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Inorganic Arsenic-Related Changes in the Stromal Tumor Microenvironment in a Prostate Cancer Cell-Conditioned Media Model von Shearer, Joseph J, Wold, Eric A, Umbaugh, Charles S, Lichti, Cheryl F, Nilsson, Carol L, Figueiredo, Marxa L

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