NUDT2 initiates viral RNA degradation by removal of 5′-phosphates von Laudenbach, Beatrice T., Krey, Karsten, Emslander, Quirin, Andersen, Line Lykke, Reim, Alexander, Scaturro, Pietro, Mundigl, Sarah, Dächert, Christopher, Manske, Katrin, Moser, Markus, Ludwig, Janos, Wohlleber, Dirk, Kröger, Andrea, Binder, Marco, Pichlmair, Andreas

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Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the L... von Grünwald, Barbara, Harant, Veronika, Schaten, Susanne, Frühschütz, Monika, Spallek, Ria, Höchst, Bastian, Stutzer, Katharina, Berchtold, Sonja, Erkan, Mert, Prokopchuk, Olga, Martignoni, Marc, Esposito, Irene, Heikenwalder, Mathias, Gupta, Aayush, Siveke, Jens, Saftig, Paul, Knolle, Percy, Wohlleber, Dirk, Krüger, Achim

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Single organelle analysis to characterize mitochondrial function and crosstalk during viral infection von Schneider, Annika, Kurz, Sandra, Manske, Katrin, Janas, Marianne, Heikenwälder, Mathias, Misgeld, Thomas, Aichler, Michaela, Weissmann, Sebastian Felix, Zischka, Hans, Knolle, Percy, Wohlleber, Dirk

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In Vivo Bioluminescence Imaging of HBV Replicating Hepatocytes Allows for the Monitoring of Anti-Viral Immunity von Manske, Katrin, Schneider, Annika, Ko, Chunkyu, Knolle, Percy A., Steiger, Katja, Protzer, Ulrike, Wohlleber, Dirk

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Translation of Angiotensin-Converting Enzyme 2 upon Liver- and Lung-Targeted Delivery of Optimized Chemically Modified mRNA von Schrom, Eva, Huber, Maja, Aneja, Manish, Dohmen, Christian, Emrich, Daniela, Geiger, Johannes, Hasenpusch, Günther, Herrmann-Janson, Annika, Kretzschmann, Verena, Mykhailyk, Olga, Pasewald, Tamara, Oak, Prajakta, Hilgendorff, Anne, Wohlleber, Dirk, Hoymann, Heinz-Gerd, Schaudien, Dirk, Plank, Christian, Rudolph, Carsten, Kubisch-Dohmen, Rebekka

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Pioglitazone-Mediated Peroxisome Proliferator-Activated Receptor gamma Activation Aggravates Murine Immune-Mediated Hepatitis von Schulte, Rike, Wohlleber, Dirk, Unrau, Ludmilla, Geers, Bernd, Metzger, Christina, Erhardt, Annette, Tiegs, Gisa, van Rooijen, Nico, Heukamp, Lukas C., Klotz, Luisa, Knolle, Percy A., Diehl, Linda

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Improving Therapeutic Vaccination against Hepatitis B-Insights from Preclinical Models of Immune Therapy against Persistent Hepatitis B Virus Infection von Knolle, Percy A., Huang, Li-Rung, Kosinska, Anna, Wohlleber, Dirk, Protzer, Ulrike

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Liver-Primed Memory T Cells Generated under Noninflammatory Conditions Provide Anti-infectious Immunity von Böttcher, Jan P., Schanz, Oliver, Wohlleber, Dirk, Abdullah, Zeinab, Debey-Pascher, Svenja, Staratschek-Jox, Andrea, Höchst, Bastian, Hegenbarth, Silke, Grell, Jessica, Limmer, Andreas, Atreya, Imke, Neurath, Markus F., Busch, Dirk H., Schmitt, Edgar, van Endert, Peter, Kolanus, Waldemar, Kurts, Christian, Schultze, Joachim L., Diehl, Linda, Knolle, Percy A.

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Transfer of MHC-class-I molecules among liver sinusoidal cells facilitates hepatic immune surveillance von Schölzel, Katrin, Schildberg, Frank A, Welz, Meike, Börner, Carolin, Geiger, Sergej, Kurts, Christian, Heikenwälder, Mathias, Knolle, Percy A, Wohlleber, Dirk

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MHC Class I-Restricted TCR-Transgenic CD4+T Cells Against STEAP1 Mediate Local Tumor Control of Ewing Sarcoma In Vivo von Schober, Sebastian J., Thiede, Melanie, Gassmann, Hendrik, Prexler, Carolin, Xue, Busheng, Schirmer, David, Wohlleber, Dirk, Stein, Stefanie, Grunewald, Thomas G. P., Busch, Dirk H., Richter, Guenther H. S., Burdach, Stefan E. G., Thiel, Uwe

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High precision-cut liver slice model to study cell-autonomous antiviral defense of hepatocytes within their microenvironment von Brugger, Marcus, Laschinger, Melanie, Lampl, Sandra, Schneider, Annika, Manske, Katrin, Esfandyari, Dena, Hüser, Norbert, Hartmann, Daniel, Steiger, Katja, Engelhardt, Stefan, Wohlleber, Dirk, Knolle, Percy A.

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TNF-Induced Target Cell Killing by CTL Activated through Cross-Presentation von Wohlleber, Dirk, Kashkar, Hamid, Gärtner, Katja, Frings, Marianne K., Odenthal, Margarete, Hegenbarth, Silke, Börner, Carolin, Arnold, Bernd, Hämmerling, Günter, Nieswandt, Bernd, van Rooijen, Nico, Limmer, Andreas, Cederbrant, Karin, Heikenwalder, Mathias, Pasparakis, Manolis, Protzer, Ulrike, Dienes, Hans-Peter, Kurts, Christian, Krönke, Martin, Knolle, Percy A.

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Immunological functions of liver sinusoidal endothelial cells von Knolle, Percy A, Wohlleber, Dirk

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TOP-050 - “Swarm hunting” of virus-specific CD8 T cells together with auto-aggressive CD8 T cells to achieve efficient killing of virus-infected hepatocytes von Tenreiro, Ariane Eceiza, Dudek, Michael, Wohlleber, Dirk, Knolle, Percy A.

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“Swarm hunting” of virus-specific CD8 T cells together with auto-aggressive CD8 T cells to achieve efficient killing of virus-infected hepatocytes von Tenreiro, Ariane Eceiza, Dudek, Michael, Wohlleber, Dirk, Knolle, Percy A.

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TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection von Alfei, Francesca, Kanev, Kristiyan, Hofmann, Maike, Wu, Ming, Ghoneim, Hazem E., Roelli, Patrick, Utzschneider, Daniel T., von Hoesslin, Madlaina, Cullen, Jolie G., Fan, Yiping, Eisenberg, Vasyl, Wohlleber, Dirk, Steiger, Katja, Merkler, Doron, Delorenzi, Mauro, Knolle, Percy A., Cohen, Cyrille J., Thimme, Robert, Youngblood, Benjamin, Zehn, Dietmar

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Metabolic Activation of Intrahepatic CD8+ T Cells and NKT Cells Causes Nonalcoholic Steatohepatitis and Liver Cancer via Cross-Talk with Hepatocytes von Wolf, Monika Julia, Adili, Arlind, Piotrowitz, Kira, Abdullah, Zeinab, Boege, Yannick, Stemmer, Kerstin, Ringelhan, Marc, Simonavicius, Nicole, Egger, Michèle, Wohlleber, Dirk, Lorentzen, Anna, Einer, Claudia, Schulz, Sabine, Clavel, Thomas, Protzer, Ulrike, Thiele, Christoph, Zischka, Hans, Moch, Holger, Tschöp, Matthias, Tumanov, Alexei V., Haller, Dirk, Unger, Kristian, Karin, Michael, Kopf, Manfred, Knolle, Percy, Weber, Achim, Heikenwalder, Mathias

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TOP-053 - Rheostat function of liver sinusoidal endothelial cells and macrophages limiting antiviral CD8 T cell immunity in the liver von Fürst, Anna, Chattopadhyay, Sutirtha, Wintersteller, Hannah, Wohlleber, Dirk, Bosch, Miriam, Knolle, Percy A.

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Rheostat function of liver sinusoidal endothelial cells and macrophages limiting antiviral CD8 T cell immunity in the liver von Fürst, Anna, Chattopadhyay, Sutirtha, Wintersteller, Hannah, Wohlleber, Dirk, Bosch, Miriam, Knolle, Percy A.

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Analysis of Mitochondria by Single-Organelle Resolution von Harbauer, Angelika B, Schneider, Annika, Wohlleber, Dirk

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