Identification and characterization of PERK activators by phenotypic screening and their effects on NRF2 activation von Xie, Wensheng, Pariollaud, Marie, Wixted, William E, Chitnis, Nilesh, Fornwald, James, Truong, Maggie, Pao, Christina, Liu, Yan, Ames, Robert S, Callahan, James, Solari, Roberto, Sanchez, Yolanda, Diehl, Alan, Li, Hu

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Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2‑Related Factor 2 (KEAP1:NRF2) Protein–Protein Interaction with High Cell Potency Identi... von Davies, Thomas G, Wixted, William E, Coyle, Joseph E, Griffiths-Jones, Charlotte, Hearn, Keisha, McMenamin, Rachel, Norton, David, Rich, Sharna J, Richardson, Caroline, Saxty, Gordon, Willems, Henriëtte M. G, Woolford, Alison J.-A, Cottom, Joshua E, Kou, Jen-Pyng, Yonchuk, John G, Feldser, Heidi G, Sanchez, Yolanda, Foley, Joseph P, Bolognese, Brian J, Logan, Gregory, Podolin, Patricia L, Yan, Hongxing, Callahan, James F, Heightman, Tom D, Kerns, Jeffrey K

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In silico and in vitro evaluation of exonic and intronic off-target effects form a critical element of therapeutic ASO gapmer optimization von Kamola, Piotr J, Kitson, Jeremy D A, Turner, Gemma, Maratou, Klio, Eriksson, Sofie, Panjwani, Aliza, Warnock, Linda C, Douillard Guilloux, Gaelle A, Moores, Kitty, Koppe, Emma L, Wixted, William E, Wilson, Paul A, Gooderham, Nigel J, Gant, Timothy W, Clark, Kenneth L, Hughes, Stephen A, Edbrooke, Mark R, Parry, Joel D

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Fragment-Guided Discovery of Pyrazole Carboxylic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2 Related Factor 2 (KEAP1:NRF2) Protein−Protei... von Norton, David, Bonnette, William G, Callahan, James F, Carr, Maria G, Griffiths-Jones, Charlotte M, Heightman, Tom D, Kerns, Jeffrey K, Nie, Hong, Rich, Sharna J, Richardson, Caroline, Rumsey, William, Sanchez, Yolanda, Verdonk, Marcel L, Willems, Henriëtte M. G, Wixted, William E, Woolford, Alison J.-A, Wu, Zining, Davies, Thomas G

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Characterization of the Potent, Selective Nrf2 Activator, 3-(Pyridin-3-Ylsulfonyl)-5-(Trifluoromethyl)-2H-Chromen-2-One, in Cellular and In Vivo Models of Pulmonary Oxidative Stres... von Yonchuk, John G, Foley, Joseph P, Bolognese, Brian J, Logan, Gregory, Wixted, William E, Kou, Jen-Pyng, Chalupowicz, Diana G, Feldser, Heidi G, Sanchez, Yolanda, Nie, Hong, Callahan, James F, Kerns, Jeffrey K, Podolin, Patricia L

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Characterization of the Potent, Selective Nrf2 Activator, 3-(Pyridin-3-Ylsulfonyl)-5-(Trifluoromethyl)-2 H -Chromen-2-One, in Cellular and In Vivo Models of Pulmonary Oxidative Str... von Yonchuk, John G, Foley, Joseph P, Bolognese, Brian J, Logan, Gregory, Wixted, William E, Kou, Jen-Pyng, Chalupowicz, Diana G, Feldser, Heidi G, Sanchez, Yolanda, Nie, Hong, Callahan, James F, Kerns, Jeffrey K, Podolin, Patricia L

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Radioligand Binding and Functional Characterization of Recombinant Human NmU1 and NmU2 Receptors Stably Expressed in Clonal Human Embryonic Kidney-293 Cells von Aiyar, Nambi, Disa, Jyoti, Foley, James J., Buckley, Peter T., Wixted, William E., Pullen, Mark, Shabon, Usman, Dul, Edward, Szekeres, Philip G., Elshourbagy, Nabil A., Sarau, Henry M., Appelbaum, Edward, Bolaky, Jane

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Nonpeptidic urotensin‐II receptor antagonists I: in vitro pharmacological characterization of SB‐706375 von Douglas, Stephen A, Behm, David J, Aiyar, Nambi V, Naselsky, Diane, Disa, Jyoti, Brooks, David P, Ohlstein, Eliot H, Gleason, John G, Sarau, Henry M, Foley, James J, Buckley, Peter T, Schmidt, Dulcie B, Wixted, William E, Widdowson, Katherine, Riley, Graham, Jin, Jian, Gallagher, Timothy F, Schmidt, Stanley J, Ridgers, Lance, Christmann, Lisa T, Keenan, Richard M, Knight, Steven D, Dhanak, Dashyant

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The neuromedin B receptor antagonist, BIM‐23127, is a potent antagonist at human and rat urotensin‐II receptors von Herold, Christopher L, Behm, David J, Buckley, Peter T, Foley, James J, Wixted, William E, Sarau, Henry M, Douglas, Stephen A

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A model to identify novel targets involved in oxidative stress-induced apoptosis in human lung epithelial cells by RNA interference von Wixted, William E., Kitson, Chris, Colebrook, Jayne C., Roberts, Emma J., Fox, Steven M., Kou, Jen P., Li, Jun U., López-Boado, Yolanda S.

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A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma von PILLAI, Sreekumar G, COUSENS, Diane J, SARAU, Henry M, SCHMIDT, Dulcie B, SPRANKLE, Catherine S, BLUMENTHAL, Malcolm N, VESTBO, Jorgen, KENNEDY-WILSON, Karen, WIXTED, William E, WAGNER, Michael J, ANDERSON, Wayne H, IGNAR, Diane M, BARNES, Ashley A, BUCKLEY, Peter T, CHIANO, Mathias N, HOSKING, Louise K, CAMERON, Lee-Ann, FLING, Mary E, FOLEY, James J, GREEN, Andrew

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Estimating the reliability of eyewitness identifications from police lineups von Wixted, John T., Mickes, Laura, Dunn, John C., Clark, Steven E., Wells, William

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Cognitive Behavioural Therapy to Optimize Post-Operative Fracture Recovery (COPE): protocol for a randomized controlled trial von Busse, Jason W., Sprague, Sheila, Del Fabbro, Gina, McKay, Paula, Thabane, Lehana, McCabe, Randi E., Nowakowski, Matilda, Shibu, Christy, Fleming, Natalie, Johal, Herman, Slobogean, Gerard, Natoli, Roman M., Gitajn, I. Leah, Schneider, Prism, Devereaux, P. J., Schemitsch, Emil H., Bhandari, Mohit, Guyatt, Gordon H., Hapidou, Eleni, Chiaramonte, Delia, Kehlet, Henrick, Khan, James, Johnson, Aaron, Heels-Ansdell, Diane, Bzovsky, Sofia, Petrisor, Brad A., Williams, Dale, Ristevski, Bill, Al-Asiri, Jamal, Denkers, Matthew, Rajaratnam, Kris, Gallant, Jodi L., MacRae, Sarah, Pusztai, Kaitlyn, Renaud, Sara, Johal, Nicki, Papp, Steven, Lalonde, Karl-Andre, Meulenkamp, Bradley, Liew, Allan, Mistry, Manisha, Gammon, Braden, Gofton, Wade, Wilkin, Geoffrey, Dodd-Moher, Melanie, Puskas, David, Marion, Travis, Lefrancois, Tina, Payandeh, Jubin, Cullinan, Claude, Wilson, Tracy, Droll, Kurt, Riediger, Michael, Siddiqui, Rabail, Littlefield, Shalyn, Chahal, Simrun, Wagar, Paige, Schneider, Prism S., Ogunleye, Tosin, Cherppukaran, Tanya, Lienhard, Karin, Smith, Nicholas, Anthony, Sarah, Butt, Krista, Selby, LaShann, Kovvur, Murali, Lawrence, Joshua, Sampson, Skyler, Turner, Kristin, Jaeblon, Todd, Demyanovich, Haley K., Talwar, Sneh, Benzel, Caroline, Chockbengboun, Theresa, Mullin, Devin, Bateman, Logan, Christian, Melanie, DePalo, Peter, Appleton, Paul J., Wixted, John J., Rodriguez, Edward K., McTague, Michael F., Wagner, Katiri, Brackpool, Kristina, Hegermiller, Kate, Nguyen, Nhi, Fentz, Courteney, Diaz, Maricela, Niceley, Jill, Jeray, Kyle J., Schaller, Thomas M., Sridhar, Michael S., Adams, John D., Gurich, Richard W., Tanner, Stephanie L., Adams, Kyle, Donohue, Michelle, Bray, Emily, Brignull, Calleigh, Sprouse, Harper

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Correction: Cognitive Behavioural Therapy to Optimize Post-Operative Fracture Recovery (COPE): protocol for a randomized controlled trial von Del Fabbro, Gina, McKay, Paula, Thabane, Lehana, McCabe, Randi E, Nowakowski, Matilda, Shibu, Christy, Fleming, Natalie, Johal, Herman, Slobogean, Gerard, Natoli, Roman M, Gitajn, I. Leah, Schneider, Prism, Devereaux, P. J, Schemitsch, Emil H, Bhandari, Mohit, Guyatt, Gordon H, Hapidou, Eleni, Chiaramonte, Delia, Kehlet, Henrick, Khan, James, Johnson, Aaron, Heels-Ansdell, Diane, Bzovsky, Sofia, Petrisor, Brad A, Williams, Dale, Ristevski, Bill, Al-Asiri, Jamal, Denkers, Matthew, Rajaratnam, Kris, Gallant, Jodi L, MacRae, Sarah, Pusztai, Kaitlyn, Renaud, Sara, Johal, Nicki, Papp, Steven, Lalonde, Karl-Andre, Meulenkamp, Bradley, Liew, Allan, Mistry, Manisha, Gammon, Braden, Gofton, Wade, Wilkin, Geoffrey, Dodd-Moher, Melanie, Puskas, David, Marion, Travis, Lefrancois, Tina, Payandeh, Jubin, Cullinan, Claude, Wilson, Tracy, Droll, Kurt, Riediger, Michael, Siddiqui, Rabail, Littlefield, Shalyn, Chahal, Simrun, Wagar, Paige, Schneider, Prism S, Ogunleye, Tosin, Cherppukaran, Tanya, Lienhard, Karin, Smith, Nicholas, Anthony, Sarah, Butt, Krista, Selby, La Shann, Kovvur, Murali, Lawrence, Joshua, Sampson, Skyler, Turner, Kristin, Jaeblon, Todd, Demyanovich, Haley K, Talwar, Sneh, Benzel, Caroline, Chockbengboun, Theresa, Mullin, Devin, Bateman, Logan, Christian, Melanie, DePalo, Peter, Appleton, Paul J, Wixted, John J, Rodriguez, Edward K, McTague, Michael F, Wagner, Katiri, Brackpool, Kristina, Hegermiller, Kate, Nguyen, Nhi, Fentz, Courteney, Diaz, Maricela, Niceley, Jill, Jeray, Kyle J, Schaller, Thomas M, Sridhar, Michael S, Adams, John D, Gurich, Richard W, Tanner, Stephanie L, Adams, Kyle, Donohue, Michelle, Bray, Emily, Brignull, Calleigh, Sprouse, Harper

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In-person cognitive behavioural therapy vs. usual care after surgical management of extremity fractures: an unsuccessful feasibility trial von Gouveia, Kyle, Sprague, Sheila, Gallant, Jodi, Del Fabbro, Gina, Leonard, Jordan, Bzovsky, Sofia, McKay, Paula, Busse, Jason W

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