Glycosyltransferases: structures, functions, and mechanisms von Lairson, L L, Henrissat, B, Davies, G J, Withers, S G

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N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases von Santana, A G, Vadlamani, G, Mark, B L, Withers, S G

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Understanding viral neuraminidase inhibition by substituted difluorosialic acids von Weck, S, Robinson, K, Smith, M. R, Withers, S. G

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The structure of the Mycobacterium smegmatis trehalose synthase reveals an unusual active site configuration and acarbose-binding mode von Caner, Sami, Nguyen, Nham, Aguda, Adeleke, Zhang, Ran, Pan, Yuan T, Withers, Stephen G, Brayer, Gary D

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Identification of the Acid/Base Catalyst in Agrobacterium faecalis .beta.-Glucosidase by Kinetic Analysis of Mutants von Wang, Q, Trimbur, D, Graham, R, Warren, R. A. J, Withers, S. G

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Phosphodiesters serve as potentially tunable aglycones for fluoro sugar inactivators of retaining β-glycosidases von Rempel, B P, Withers, S G

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Structure and Mechanism of Chitin Deacetylase from the Fungal Pathogen Colletotrichum lindemuthianum von Blair, David E, Hekmat, Omid, Schüttelkopf, Alexander W, Shrestha, Binesh, Tokuyasu, Ken, Withers, Stephen G, van Aalten, Daan M. F

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Approaches to labeling and identification of active site residues in glycosidases von Withers, Stephen G., Aebersold, Ruedi

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Mechanism of Agrobacterium .beta.-glucosidase: kinetic studies von Kempton, Julie B, Withers, Stephen G

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Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate von Withers, Stephen G, Vocadlo, David J, Davies, Gideon J, Laine, Roger

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Glu-537, not Glu-461, is the nucleophile in the active site of (lac Z) beta-galactosidase from Escherichia coli von GEBLER, JC, AEBERSOLD, R, WITHERS, SG

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X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the α-amylase family von Uitdehaag, Joost C. M, Mosi, Renée, Kalk, Kor H, van der Veen, Bart A, Dijkhuizen, Lubbert, Withers, Stephen G, Dijkstra, Bauke W

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Structure-based mutagenic analysis of mechanism and substrate specificity in mammalian glycosyltransferases: porcine ST3Gal-I von Rakic, Bojana, Rao, Francesco V, Freimann, Karen, Wakarchuk, Warren, Strynadka, Natalie C J, Withers, Stephen G

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Changing Enzymic Reaction Mechanisms by Mutagenesis: Conversion of a Retaining Glucosidase to an Inverting Enzyme von Wang, Qingping, Graham, R. W, Trimbur, D, Warren, R. A. J, Withers, S. G

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Identification of the catalytic nucleophile of the Family 31 alpha-glucosidase from Aspergillus niger via trapping of a 5-fluoroglycosyl-enzyme intermediate von Lee, S S, He, S, Withers, S G

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Pharmacological enhancement of beta-hexosaminidase activity in fibroblasts from adult Tay-Sachs and Sandhoff Patients von Tropak, Michael B, Reid, Stephen P, Guiral, Marianne, Withers, Stephen G, Mahuran, Don

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Enzymatic Synthesis of Carbon−Fluorine Bonds von Zechel, David L, Reid, Stephen P, Nashiru, Oyekanmi, Mayer, Christoph, Stoll, Dominik, Jakeman, David L, Warren, R. Antony J, Withers, Stephen G

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BINDING-ENERGY AND CATALYSIS - FLUORINATED AND DEOXYGENATED GLYCOSIDES AS MECHANISTIC PROBES OF ESCHERICHIA-COLI (LACZ) BETA-GALACTOSIDASE von MCCARTER, JD, ADAM, MJ, WITHERS, SG

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Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analog von Strynadka, Natalie C J, Chiu, Cecilia P C, Watts, Andrew G, Lairson, Luke L, Gilbert, Michel, Lim, Daniel, Wakarchuk, Warren W, Withers, Stephen G

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Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase von Amaya, Marı́a Fernanda, Watts, Andrew G, Damager, Iben, Wehenkel, Annemarie, Nguyen, Tong, Buschiazzo, Alejandro, Paris, Gastón, Frasch, A.Carlos, Withers, Stephen G, Alzari, Pedro M

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