A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome von Wiseman, Frances K., Al-Janabi, Tamara, Hardy, John, Karmiloff-Smith, Annette, Nizetic, Dean, Tybulewicz, Victor L. J., Fisher, Elizabeth M. C., Strydom, André

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Rodent Modeling of Alzheimer's Disease in Down Syndrome: In vivo and ex vivo Approaches von Farrell, Clíona, Mumford, Paige, Wiseman, Frances K.

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Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome von Cannavo, Claudia, Cleverley, Karen, Maduro, Cheryl, Mumford, Paige, Moulding, Dale, Fisher, Elizabeth M C, Wiseman, Frances K

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Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome von Gribble, Susan M, Wiseman, Frances K, Clayton, Stephen, Prigmore, Elena, Langley, Elizabeth, Yang, Fengtang, Maguire, Sean, Fu, Beiyuan, Rajan, Diana, Sheppard, Olivia, Scott, Carol, Hauser, Heidi, Stephens, Philip J, Stebbings, Lucy A, Ng, Bee Ling, Fitzgerald, Tomas, Quail, Michael A, Banerjee, Ruby, Rothkamm, Kai, Tybulewicz, Victor L J, Fisher, Elizabeth M C, Carter, Nigel P

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Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer's disease von Startin, Carla M, Ashton, Nicholas J, Hamburg, Sarah, Hithersay, Rosalyn, Wiseman, Frances K, Mok, Kin Y, Hardy, John, Lleó, Alberto, Lovestone, Simon, Parnetti, Lucilla, Zetterberg, Henrik, Hye, Abdul, Strydom, André

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The effects of Cstb duplication on APP/amyloid-β pathology and cathepsin B activity in a mouse model von Wu, Yixing, Whittaker, Heather T, Noy, Suzanna, Cleverley, Karen, Brault, Veronique, Herault, Yann, Fisher, Elizabeth M C, Wiseman, Frances K

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UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation von Tiedemann, Rochelle L, Hrit, Joel, Du, Qian, Wiseman, Ashley K, Eden, Hope E, Dickson, Bradley M, Kong, Xiangqian, Chomiak, Alison A, Vaughan, Robert M, Tibben, Bailey M, Hebert, Jakob M, David, Yael, Zhou, Wanding, Baylin, Stephen B, Jones, Peter A, Clark, Susan J, Rothbart, Scott B

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Altered Hippocampal-Prefrontal Neural Dynamics in Mouse Models of Down Syndrome von Chang, Pishan, Bush, Daniel, Schorge, Stephanie, Good, Mark, Canonica, Tara, Shing, Nathanael, Noy, Suzanna, Wiseman, Frances K., Burgess, Neil, Tybulewicz, Victor L.J., Walker, Matthew C., Fisher, Elizabeth M.C.

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SynPull: An advanced method for studying neurodegeneration-related aggregates in synaptosomes using super-resolution microscopy von Kedia, Shekhar, Fertan, Emre, Wu, Yunzhao, Zhang, Yu P., Meisl, Georg, Lam, Jeff Y.L., K. Wiseman, Frances, McEwan, William A., Quaegebeur, Annelies, Spillantini, Maria Grazia, Danial, John S.H., Klenerman, David

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Down syndrome—recent progress and future prospects von Wiseman, Frances K., Alford, Kate A., Tybulewicz, Victor L.J., Fisher, Elizabeth M.C.

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Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models von Tosh, Justin L., Rhymes, Elena R., Mumford, Paige, Whittaker, Heather T., Pulford, Laura J., Noy, Sue J., Cleverley, Karen, Walker, Matthew C., Tybulewicz, Victor L. J., Wykes, Rob C., Fisher, Elizabeth M. C., Wiseman, Frances K.

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Reaching adults who smoke cigarettes in rural Appalachia: Rationale, design & analysis plan for a mixed-methods study disseminating pharmacy-delivered cessation treatment von Fahey, M.C., Krukowski, R.A., Anderson, R.T., Cohn, W.F., Porter, K.J., Reid, T., Wiseman, K.P., You, W., Wood, C.H., Rucker, T.W., Little, M.A.

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Reduction of Cystatin B results in increased cathepsin B activity in disomic but not Trisomy 21 human cellular and mouse models von Wu, Yixing, Cleverley, Karen, Wiseman, Frances K

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Substantially thinner internal granular layer and reduced molecular layer surface in the cerebellar cortex of the Tc1 mouse model of down syndrome – a comprehensive morphometric an... von Ma, Da, Cardoso, Manuel J., Zuluaga, Maria A., Modat, Marc, Powell, Nick M., Wiseman, Frances K., Cleary, Jon O., Sinclair, Benjamin, Harrison, Ian F., Siow, Bernard, Popuri, Karteek, Lee, Sieun, Matsubara, Joanne A., Sarunic, Marinko V., Beg, Mirza Faisal, Tybulewicz, Victor L.J., Fisher, Elizabeth M.C., Lythgoe, Mark F., Ourselin, Sebastien

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Registered Replication Report: Schooler and Engstler-Schooler (1990) von Alogna, V. K., Attaya, M.K., Aucoin, P., Bahnik, Š., Birch, S., Birt, A. R., Bornstein, B. H., Bouwmeester, S., Brandimonte, M. A., Brown, C., Buswell, K., Carlson, C., Carlson, M., Chu, S., Cislak, A., Colarusso, M., Colloff, M. F., Dellapaolera, K.S., Delvenne, J.-F., Di Domenico, A., Drummond, A., Echterhoff, G., Edlund, J. E., Eggleston, C. M., Fairfield, B., Franco, G., Gabbert, F., Gamblin, B. W., Garry, M., Gentry, R., Gilbert, E. A., Greenberg, D. L., Halberstadt, J., Hall, L., Hancock, P. J. B., Hirsch, D., Holt, G., Jackson, J. C., Jong, J., Kehn, A., Koch, C., Kopietz, R., Körner, U., Kunar, M. A., Lai, C. K., Langton, S. R. H., Leite, F. P., Mammarella, N., Marsh, J. E., McConnaughy, K. A., McCoy, S., McIntyre, A. H., Meissner, C. A., Michael, R.B., Mitchell, A.A., Mugayar-Baldocchi, M., Musselman, R., Ng, C., Nichols, A. L., Nunez, N. L., Palmer, M. A., Pappagianopoulos, J. E., Petro, M. S., Poirier, C. R., Portch, E., Rainsford, M., Rancourt, A., Romig, C., Rubínová, E., Sanson, M., Satchell, L., Sauer, J. D., Schweitzer, K., Shaheed, J., Skelton, F., Sullivan, G. A., Susa, K. J., Swanner, J. K., Thompson, W. B., Todaro, R., Ulatowska, J., Valentine, T., Verkoeijen, P. P. J. L., Vranka, M., Wade, K. A., Was, C. A., Weatherford, D., Wiseman, K., Zaksaite, T., Zuj, D. V., Zwaan, R. A.

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Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B von Wu, Yixing, Mumford, Paige, Noy, Suzanna, Cleverley, Karen, Mrzyglod, Alicja, Luo, Dinghao, van Dalen, Floris, Verdoes, Martijn, Fisher, Elizabeth M C, Wiseman, Frances K

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Publisher Correction: Genetic dissection of down syndrome‑associated alterations in APP/amyloid‑β biology using mouse models von Tosh, Justin L., Rhymes, Elena R., Mumford, Paige, Whittaker, Heather T., Pulford, Laura J., Noy, Sue J., Cleverley, Karen, Walker, Matthew C., Tybulewicz, Victor L. J., Wykes, Rob C., Fisher, Elizabeth M. C., Wiseman, Frances K.

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Chytrid infections exhibit historical spread and contemporary seasonality in a declining stream-breeding frog von Belasen, A M, Peek, R A, Adams, A J, Russell, I D, De León, M E, Adams, M J, Bettaso, J, Breedveld, K G H, Catenazzi, A, Dillingham, C P, Grear, D A, Halstead, B J, Johnson, P G, Kleeman, P M, Koo, M S, Koppl, C W, Lauder, J D, Padgett-Flohr, G, Piovia-Scott, J, Pope, K L, Vredenburg, V, Westphal, M, Wiseman, K, Kupferberg, S J

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Cell models for Down syndrome-Alzheimer's disease research von Wu, Yixing, West, Nicole R, Bhattacharyya, Anita, Wiseman, Frances K

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Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome von Powell, Nick M, Modat, Marc, Cardoso, M Jorge, Ma, Da, Holmes, Holly E, Yu, Yichao, O'Callaghan, James, Cleary, Jon O, Sinclair, Ben, Wiseman, Frances K, Tybulewicz, Victor L J, Fisher, Elizabeth M C, Lythgoe, Mark F, Ourselin, Sébastien

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