Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia von Orlando, Elena J., Han, Xia, Tribouley, Catherine, Wood, Patricia A., Leary, Rebecca J., Riester, Markus, Levine, John E., Qayed, Muna, Grupp, Stephan A., Boyer, Michael, De Moerloose, Barbara, Nemecek, Eneida R., Bittencourt, Henrique, Hiramatsu, Hidefumi, Buechner, Jochen, Davies, Stella M., Verneris, Michael R., Nguyen, Kevin, Brogdon, Jennifer L., Bitter, Hans, Morrissey, Michael, Pierog, Piotr, Pantano, Serafino, Engelman, Jeffrey A., Winckler, Wendy

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RNA-SeQC: RNA-seq metrics for quality control and process optimization von DELUCA, David S, LEVIN, Joshua Z, SIVACHENKO, Andrey, FENNELL, Timothy, NAZAIRE, Marc-Danie, WILLIAMS, Chris, REICH, Michael, WINCKLER, Wendy, GETZ, Gad

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The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans von Ardlie, Kristin G., Deluca, David S., Segrè, Ayellet V., Sullivan, Timothy J., Young, Taylor R., Gelfand, Ellen T., Trowbridge, Casandra A., Maller, Julian B., Tukiainen, Taru, Lek, Monkol, Ward, Lucas D., Kheradpour, Pouya, Iriarte, Benjamin, Meng, Yan, Palmer, Cameron D., Esko, Tõnu, Winckler, Wendy, Hirschhorn, Joel N., Kellis, Manolis, MacArthur, Daniel G., Getz, Gad, Shabalin, Andrey A., Li, Gen, Zhou, Yi-Hui, Nobel, Andrew B., Rusyn, Ivan, Wright, Fred A., Lappalainen, Tuuli, Ferreira, Pedro G., Ongen, Halit, Rivas, Manuel A., Battle, Alexis, Mostafavi, Sara, Monlong, Jean, Sammeth, Michael, Mele, Marta, Reverter, Ferran, Goldmann, Jakob M., Koller, Daphne, Guigó, Roderic, McCarthy, Mark I., Dermitzakis, Emmanouil T., Gamazon, Eric R., Im, Hae Kyung, Konkashbaev, Anuar, Nicolae, Dan L., Cox, Nancy J., Flutre, Timothée, Wen, Xiaoquan, Stephens, Matthew, Pritchard, Jonathan K., Tu, Zhidong, Zhang, Bin, Huang, Tao, Long, Quan, Lin, Luan, Yang, Jialiang, Zhu, Jun, Liu, Jun, Brown, Amanda, Mestichelli, Bernadette, Tidwell, Denee, Lo, Edmund, Salvatore, Mike, Shad, Saboor, Thomas, Jeffrey A., Lonsdale, John T., Moser, Michael T., Gillard, Bryan M., Karasik, Ellen, Ramsey, Kimberly, Choi, Christopher, Foster, Barbara A., Syron, John, Fleming, Johnell, Magazine, Harold, Hasz, Rick, Walters, Gary D., Bridge, Jason P., Miklos, Mark, Sullivan, Susan, Barker, Laura K., Traino, Heather M., Mosavel, Maghboeba, Siminoff, Laura A., Valley, Dana R., Rohrer, Daniel C., Jewell, Scott D., Branton, Philip A., Sobin, Leslie H., Barcus, Mary, Qi, Liqun, McLean, Jeffrey, Hariharan, Pushpa, Um, Ki Sung, Wu, Shenpei, Tabor, David, Shive, Charles, Smith, Anna M., Buia, Stephen A.

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Absolute quantification of somatic DNA alterations in human cancer von Carter, Scott L, Cibulskis, Kristian, Helman, Elena, McKenna, Aaron, Shen, Hui, Zack, Travis, Laird, Peter W, Onofrio, Robert C, Winckler, Wendy, Weir, Barbara A, Beroukhim, Rameen, Pellman, David, Levine, Douglas A, Lander, Eric S, Meyerson, Matthew, Getz, Gad

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Punctuated Evolution of Prostate Cancer Genomes von Baca, Sylvan C., Prandi, Davide, Lawrence, Michael S., Mosquera, Juan Miguel, Romanel, Alessandro, Drier, Yotam, Park, Kyung, Kitabayashi, Naoki, MacDonald, Theresa Y., Ghandi, Mahmoud, Van Allen, Eliezer, Kryukov, Gregory V., Sboner, Andrea, Theurillat, Jean-Philippe, Soong, T. David, Nickerson, Elizabeth, Auclair, Daniel, Tewari, Ashutosh, Beltran, Himisha, Onofrio, Robert C., Boysen, Gunther, Guiducci, Candace, Barbieri, Christopher E., Cibulskis, Kristian, Sivachenko, Andrey, Carter, Scott L., Saksena, Gordon, Voet, Douglas, Ramos, Alex H., Winckler, Wendy, Cipicchio, Michelle, Ardlie, Kristin, Kantoff, Philip W., Berger, Michael F., Gabriel, Stacey B., Golub, Todd R., Meyerson, Matthew, Lander, Eric S., Elemento, Olivier, Getz, Gad, Demichelis, Francesca, Rubin, Mark A., Garraway, Levi A.

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Mutational heterogeneity in cancer and the search for new cancer-associated genes von Lawrence, Michael S., Stojanov, Petar, Polak, Paz, Kryukov, Gregory V., Cibulskis, Kristian, Sivachenko, Andrey, Carter, Scott L., Stewart, Chip, Mermel, Craig H., Roberts, Steven A., Kiezun, Adam, Hammerman, Peter S., McKenna, Aaron, Drier, Yotam, Zou, Lihua, Ramos, Alex H., Pugh, Trevor J., Stransky, Nicolas, Helman, Elena, Kim, Jaegil, Sougnez, Carrie, Ambrogio, Lauren, Nickerson, Elizabeth, Shefler, Erica, Cortés, Maria L., Auclair, Daniel, Saksena, Gordon, Voet, Douglas, Noble, Michael, DiCara, Daniel, Lin, Pei, Lichtenstein, Lee, Heiman, David I., Fennell, Timothy, Imielinski, Marcin, Hernandez, Bryan, Hodis, Eran, Baca, Sylvan, Dulak, Austin M., Lohr, Jens, Landau, Dan-Avi, Wu, Catherine J., Melendez-Zajgla, Jorge, Hidalgo-Miranda, Alfredo, Koren, Amnon, McCarroll, Steven A., Mora, Jaume, Lee, Ryan S., Crompton, Brian, Onofrio, Robert, Parkin, Melissa, Winckler, Wendy, Ardlie, Kristin, Gabriel, Stacey B., Roberts, Charles W. M., Biegel, Jaclyn A., Stegmaier, Kimberly, Bass, Adam J., Garraway, Levi A., Meyerson, Matthew, Golub, Todd R., Gordenin, Dmitry A., Sunyaev, Shamil, Lander, Eric S., Getz, Gad

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The Mutational Landscape of Head and Neck Squamous Cell Carcinoma von Stransky, Nicolas, Egloff, Ann Marie, Tward, Aaron D., Kostic, Aleksandar D., Cibulskis, Kristian, Sivachenko, Andrey, Kryukov, Gregory V., Lawrence, Michael S., Sougnez, Carrie, McKenna, Aaron, Shefler, Erica, Ramos, Alex H., Stojanov, Petar, Carter, Scott L., Voet, Douglas, Cortés, Maria L., Auclair, Daniel, Berger, Michael F., Saksena, Gordon, Guiducci, Candace, Onofrio, Robert C., Parkin, Melissa, Romkes, Marjorie, Weissfeld, Joel L., Seethala, Raja R., Wang, Lin, Rangel-Escareño, Claudia, Fernandez-Lopez, Juan Carlos, Hidalgo-Miranda, Alfredo, Melendez-Zajgla, Jorge, Winckler, Wendy, Ardlie, Kristin, Gabriel, Stacey B., Meyerson, Matthew, Lander, Eric S., Getz, Gad, Golub, Todd R., Garraway, Levi A., Grandis, Jennifer R.

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A Landscape of Driver Mutations in Melanoma von Hodis, Eran, Watson, Ian R., Kryukov, Gregory V., Arold, Stefan T., Imielinski, Marcin, Theurillat, Jean-Philippe, Nickerson, Elizabeth, Auclair, Daniel, Li, Liren, Place, Chelsea, DiCara, Daniel, Ramos, Alex H., Lawrence, Michael S., Cibulskis, Kristian, Sivachenko, Andrey, Voet, Douglas, Saksena, Gordon, Stransky, Nicolas, Onofrio, Robert C., Winckler, Wendy, Ardlie, Kristin, Wagle, Nikhil, Wargo, Jennifer, Chong, Kelly, Morton, Donald L., Stemke-Hale, Katherine, Chen, Guo, Noble, Michael, Meyerson, Matthew, Ladbury, John E., Davies, Michael A., Gershenwald, Jeffrey E., Wagner, Stephan N., Hoon, Dave S.B., Schadendorf, Dirk, Lander, Eric S., Gabriel, Stacey B., Getz, Gad, Garraway, Levi A., Chin, Lynda

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Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma von Fuchs, Bryan C., Hoshida, Yujin, Fujii, Tsutomu, Wei, Lan, Yamada, Suguru, Lauwers, Gregory Y., McGinn, Christopher M., DePeralta, Danielle K., Chen, Xintong, Kuroda, Toshihiko, Lanuti, Michael, Schmitt, Anthony D., Gupta, Supriya, Crenshaw, Andrew, Onofrio, Robert, Taylor, Bradley, Winckler, Wendy, Bardeesy, Nabeel, Caravan, Peter, Golub, Todd R., Tanabe, Kenneth K.

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High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines von Yu, Channing, Mannan, Aristotle M, Yvone, Griselda Metta, Ross, Kenneth N, Zhang, Yan-Ling, Marton, Melissa A, Taylor, Bradley R, Crenshaw, Andrew, Gould, Joshua Z, Tamayo, Pablo, Weir, Barbara A, Tsherniak, Aviad, Wong, Bang, Garraway, Levi A, Shamji, Alykhan F, Palmer, Michelle A, Foley, Michael A, Winckler, Wendy, Schreiber, Stuart L, Kung, Andrew L, Golub, Todd R

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The genomic complexity of primary human prostate cancer von Berger, Michael F., Lawrence, Michael S., Demichelis, Francesca, Drier, Yotam, Cibulskis, Kristian, Sivachenko, Andrey Y., Sboner, Andrea, Esgueva, Raquel, Pflueger, Dorothee, Sougnez, Carrie, Onofrio, Robert, Carter, Scott L., Park, Kyung, Habegger, Lukas, Ambrogio, Lauren, Fennell, Timothy, Parkin, Melissa, Saksena, Gordon, Voet, Douglas, Ramos, Alex H., Pugh, Trevor J., Wilkinson, Jane, Fisher, Sheila, Winckler, Wendy, Mahan, Scott, Ardlie, Kristin, Baldwin, Jennifer, Simons, Jonathan W., Kitabayashi, Naoki, MacDonald, Theresa Y., Kantoff, Philip W., Chin, Lynda, Gabriel, Stacey B., Gerstein, Mark B., Golub, Todd R., Meyerson, Matthew, Tewari, Ashutosh, Lander, Eric S., Getz, Gad, Rubin, Mark A., Garraway, Levi A.

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Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1 von Verhaak, Roel G.W., Hoadley, Katherine A., Purdom, Elizabeth, Wang, Victoria, Qi, Yuan, Wilkerson, Matthew D., Miller, C. Ryan, Ding, Li, Golub, Todd, Mesirov, Jill P., Alexe, Gabriele, Lawrence, Michael, O'Kelly, Michael, Tamayo, Pablo, Weir, Barbara A., Gabriel, Stacey, Winckler, Wendy, Gupta, Supriya, Jakkula, Lakshmi, Feiler, Heidi S., Hodgson, J. Graeme, James, C. David, Sarkaria, Jann N., Brennan, Cameron, Kahn, Ari, Spellman, Paul T., Wilson, Richard K., Speed, Terence P., Gray, Joe W., Meyerson, Matthew, Getz, Gad, Perou, Charles M., Hayes, D. Neil

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The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits von Voight, Benjamin F, Kang, Hyun Min, Ding, Jun, Palmer, Cameron D, Sidore, Carlo, Chines, Peter S, Burtt, Noël P, Fuchsberger, Christian, Li, Yanming, Erdmann, Jeanette, Frayling, Timothy M, Heid, Iris M, Jackson, Anne U, Johnson, Toby, Kilpeläinen, Tuomas O, Lindgren, Cecilia M, Morris, Andrew P, Prokopenko, Inga, Randall, Joshua C, Saxena, Richa, Soranzo, Nicole, Speliotes, Elizabeth K, Teslovich, Tanya M, Wheeler, Eleanor, Maguire, Jared, Parkin, Melissa, Potter, Simon, Rayner, N William, Robertson, Neil, Stirrups, Kathleen, Winckler, Wendy, Sanna, Serena, Mulas, Antonella, Nagaraja, Ramaiah, Cucca, Francesco, Barroso, Inês, Deloukas, Panos, Loos, Ruth J F, Kathiresan, Sekar, Munroe, Patricia B, Newton-Cheh, Christopher, Pfeufer, Arne, Samani, Nilesh J, Schunkert, Heribert, Hirschhorn, Joel N, Altshuler, David, McCarthy, Mark I, Abecasis, Gonçalo R, Boehnke, Michael

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The landscape of somatic copy-number alteration across human cancers von Yecies, Derek, Gabriel, Stacey, Porter, Dale, Nucera, Carmelo, Antonescu, Cristina R, Chiang, Derek Y, Janne, Pasi A, Greulich, Heidi, Loo, Alice, Prensner, John, Maher, Elizabeth, Rustgi, Anil K, Ligon, Azra H, Tanaka, Kumiko E, Kaye, Frederic J, Ebert, Benjamin L, Pomeroy, Scott L, Lander, Eric S, Fletcher, Jonathan A, Okamoto, Aikou, Signoretti, Sabina, Haery, Leila, Reich, Michael, Dobson, Jennifer, Raychaudhuri, Soumya, Wei, Guo, Baselga, José, Tsao, Ming-Sound, Letai, Anthony, Getz, Gad, Liefeld, Ted, Donovan, Jerry, Levine, Ross L, Beer, David G, Daly, Mark J, Sasaki, Hidefumi, Pinchback, Reid M, Bass, Adam J, Hoffman, Carter, Ladanyi, Marc, True, Lawrence D, Cho, Yoon-Jae, Sellers, William R, Tabernero, Josep, Demichelis, Francesca, Tepper, Joel E, Golub, Todd R, Meyerson, Matthew, Boehm, Jesse S, Mermel, Craig H, Loda, Massimo, Weir, Barbara A, Beroukhim, Rameen, Singer, Samuel, Urashima, Mitsuyoshi, Gao, Qing, Lawrence, Michael S, Rubin, Mark A, Barretina, Jordi, Garraway, Levi A, Winckler, Wendy, Mc Henry, Kevin T

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Effect of predicted protein-truncating genetic variants on the human transcriptome von Rivas, Manuel A., Pirinen, Matti, Conrad, Donald F., Lek, Monkol, Tsang, Emily K., Karczewski, Konrad J., Maller, Julian B., Kukurba, Kimberly R., DeLuca, David S., Fromer, Menachem, Ferreira, Pedro G., Smith, Kevin S., Zhang, Rui, Zhao, Fengmei, Banks, Eric, Poplin, Ryan, Ruderfer, Douglas M., Purcell, Shaun M., Tukiainen, Taru, Minikel, Eric V., Stenson, Peter D., Cooper, David N., Huang, Katharine H., Sullivan, Timothy J., Nedzel, Jared, Bustamante, Carlos D., Li, Jin Billy, Daly, Mark J., Guigo, Roderic, Donnelly, Peter, Ardlie, Kristin, Sammeth, Michael, Dermitzakis, Emmanouil T., McCarthy, Mark I., Montgomery, Stephen B., Lappalainen, Tuuli, MacArthur, Daniel G.

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Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features von Pitt, Jason J., Riester, Markus, Zheng, Yonglan, Yoshimatsu, Toshio F., Sanni, Ayodele, Oluwasola, Olayiwola, Veloso, Artur, Labrot, Emma, Wang, Shengfeng, Odetunde, Abayomi, Ademola, Adeyinka, Okedere, Babajide, Mahan, Scott, Leary, Rebecca, Macomber, Maura, Ajani, Mustapha, Johnson, Ryan S., Fitzgerald, Dominic, Grundstad, A. Jason, Tuteja, Jigyasa H., Khramtsova, Galina, Zhang, Jing, Sveen, Elisabeth, Hwang, Bryce, Clayton, Wendy, Nkwodimmah, Chibuzor, Famooto, Bisola, Obasi, Esther, Aderoju, Victor, Oludara, Mobolaji, Omodele, Folusho, Akinyele, Odunayo, Adeoye, Adewunmi, Ogundiran, Temidayo, Babalola, Chinedum, MacIsaac, Kenzie, Popoola, Abiodun, Morrissey, Michael P., Chen, Lin S., Wang, Jiebiao, Olopade, Christopher O., Falusi, Adeyinka G., Winckler, Wendy, Haase, Kerstin, Van Loo, Peter, Obafunwa, John, Papoutsakis, Dimitris, Ojengbede, Oladosu, Weber, Barbara, Ibrahim, Nasiru, White, Kevin P., Huo, Dezheng, Olopade, Olufunmilayo I., Barretina, Jordi

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Somatic mutations affect key pathways in lung adenocarcinoma von Meyerson, Matthew, Wilson, Richard K, Ding, Li, Getz, Gad, Wheeler, David A, Mardis, Elaine R, McLellan, Michael D, Cibulskis, Kristian, Sougnez, Carrie, Greulich, Heidi, Muzny, Donna M, Morgan, Margaret B, Fulton, Lucinda, Fulton, Robert S, Zhang, Qunyuan, Wendl, Michael C, Lawrence, Michael S, Larson, David E, Chen, Ken, Dooling, David J, Sabo, Aniko, Hawes, Alicia C, Shen, Hua, Jhangiani, Shalini N, Lewis, Lora R, Hall, Otis, Zhu, Yiming, Mathew, Tittu, Ren, Yanru, Yao, Jiqiang, Scherer, Steven E, Clerc, Kerstin, Metcalf, Ginger A, Ng, Brian, Milosavljevic, Aleksandar, Gonzalez-Garay, Manuel L, Osborne, John R, Meyer, Rick, Shi, Xiaoqi, Tang, Yuzhu, Koboldt, Daniel C, Lin, Ling, Abbott, Rachel, Miner, Tracie L, Pohl, Craig, Fewell, Ginger, Haipek, Carrie, Schmidt, Heather, Dunford-Shore, Brian H, Kraja, Aldi, Crosby, Seth D, Sawyer, Christopher S, Vickery, Tammi, Sander, Sacha, Robinson, Jody, Winckler, Wendy, Baldwin, Jennifer, Chirieac, Lucian R, Dutt, Amit, Fennell, Tim, Hanna, Megan, Johnson, Bruce E, Onofrio, Robert C, Thomas, Roman K, Tonon, Giovanni, Weir, Barbara A, Zhao, Xiaojun, Ziaugra, Liuda, Zody, Michael C, Giordano, Thomas, Orringer, Mark B, Roth, Jack A, Spitz, Margaret R, Wistuba, Ignacio I, Ozenberger, Bradley, Good, Peter J, Chang, Andrew C, Beer, David G, Watson, Mark A, Ladanyi, Marc, Broderick, Stephen, Yoshizawa, Akihiko, Travis, William D, Pao, William, Province, Michael A, Weinstock, George M, Varmus, Harold E, Gabriel, Stacey B, Lander, Eric S, Gibbs, Richard A

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Cell-free DNA captures tumor heterogeneity and driver alterations in rapid autopsies with pre-treated metastatic cancer von Pereira, Bernard, Chen, Christopher T., Goyal, Lipika, Walmsley, Charlotte, Pinto, Christopher J., Baiev, Islam, Allen, Read, Henderson, Laura, Saha, Supriya, Reyes, Stephanie, Taylor, Martin S., Fitzgerald, Donna M., Broudo, Maida Williams, Sahu, Avinash, Gao, Xin, Winckler, Wendy, Brannon, A. Rose, Engelman, Jeffrey A., Leary, Rebecca, Stone, James R., Campbell, Catarina D., Juric, Dejan

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Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy von Sander, Chris, Meyerson, Matthew, Singer, Samuel, Barretina, Jordi, Taylor, Barry S, Banerji, Shantanu, Ramos, Alexis H, Lagos-Quintana, Mariana, DeCarolis, Penelope L, Shah, Kinjal, Socci, Nicholas D, Weir, Barbara A, Ho, Alan, Chiang, Derek Y, Reva, Boris, Mermel, Craig H, Getz, Gad, Antipin, Yevgenyi, Beroukhim, Rameen, Major, John E, Hatton, Charles, Nicoletti, Richard, Hanna, Megan, Sharpe, Ted, Fennell, Tim J, Cibulskis, Kristian, Onofrio, Robert C, Saito, Tsuyoshi, Shukla, Neerav, Lau, Christopher, Nelander, Sven, Silver, Serena J, Sougnez, Carrie, Viale, Agnes, Winckler, Wendy, Maki, Robert G, Garraway, Levi A, Lash, Alex, Greulich, Heidi, Root, David E, Sellers, William R, Schwartz, Gary K, Antonescu, Cristina R, Lander, Eric S, Varmus, Harold E, Ladanyi, Marc

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Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling von Wawer, Mathias J., Li, Kejie, Gustafsdottir, Sigrun M., Ljos, Vebjorn, Bodycombe, Nicole E., Marton, Melissa A., Sokolnicki, Katherine L., Bray, Mark-Anthony, Kemp, Melissa M., Winchester, Ellen, Taylor, Bradley, Grant, George B., Hon, C. Suk-Yee, Duvall, Jeremy R., Wilson, J. Anthony, Bittker, Joshua A., Dančík, Vlado, Narayan, Rajiv, Subramanian, Aravind, Winckler, Wendy, Golub, Todd R., Carpenter, Anne E., Shamji, Alykhan F., Schreiber, Stuart L., Clemons, Paul A.

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