Comparative assessment of gene-specific variant distribution in prenatal and postnatal cohorts tested for Noonan syndrome and related conditions von Leach, N. T., Wilson Mathews, D. R., Rosenblum, L. S., Zhou, Z., Zhu, H., Heim, R. A.

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Correction: Comparative assessment of gene-specific variant distribution in prenatal and postnatal cohorts tested for Noonan syndrome and related conditions von Leach, N.T., Wilson Mathews, D.R., Rosenblum, L.S., Zhou, Z., Zhu, H., Heim, R.A.

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Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to a... von Mathews, Rebeccah J, Robinson, James I, Battellino, Michele, Wong, Chi, Taylor, John C, Eyre, Steve, Churchman, Sarah M, Wilson, Anthony G, Isaacs, John D, Hyrich, Kimme, Barton, Anne, Plant, Darren, Savic, Sinisa, Cook, Graham P, Sarzi-Puttini, Piercarlo, Emery, Paul, Barrett, Jennifer H, Morgan, Ann W, McDermott, Michael F

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Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension von Hutchinson, Peter J, Kolias, Angelos G, Timofeev, Ivan S, Corteen, Elizabeth A, Czosnyka, Marek, Timothy, Jake, Anderson, Ian, Bulters, Diederik O, Belli, Antonio, Eynon, C. Andrew, Wadley, John, Mendelow, A. David, Mitchell, Patrick M, Wilson, Mark H, Critchley, Giles, Sahuquillo, Juan, Unterberg, Andreas, Servadei, Franco, Teasdale, Graham M, Pickard, John D, Menon, David K, Murray, Gordon D, Kirkpatrick, Peter J

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Combination of anthracyclines and anti-CD47 therapy inhibit invasive breast cancer growth while preventing cardiac toxicity by regulation of autophagy von Feliz-Mosquea, Yismeilin R., Christensen, Ashley A., Wilson, Adam S., Westwood, Brian, Varagic, Jasmina, Meléndez, Giselle C., Schwartz, Anthony L., Chen, Qing-Rong, Mathews Griner, Lesley, Guha, Rajarshi, Thomas, Craig J., Ferrer, Marc, Merino, Maria J., Cook, Katherine L., Roberts, David D., Soto-Pantoja, David R.

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Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data... von Emberson, Jonathan, PhD, Lees, Kennedy R, Prof, Lyden, Patrick, Prof, Blackwell, Lisa, BSc, Albers, Gregory, Prof, Bluhmki, Erich, Prof, Brott, Thomas, Prof, Cohen, Geoff, MSc, Davis, Stephen, Prof, Donnan, Geoffrey, Prof, Grotta, James, Prof, Howard, George, Prof, Kaste, Markku, Prof, Koga, Masatoshi, MD, von Kummer, Ruediger, Prof, Lansberg, Maarten, MD, Lindley, Richard I, Prof, Murray, Gordon, Prof, Olivot, Jean Marc, Prof, Parsons, Mark, Prof, Tilley, Barbara, Prof, Toni, Danilo, MD, Toyoda, Kazunori, Prof, Wahlgren, Nils, Prof, Wardlaw, Joanna, Prof, Whiteley, William, MD, del Zoppo, Gregory J, Prof, Baigent, Colin, Prof, Sandercock, Peter, Prof, Hacke, Werner, Prof

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Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients von Mack, Michael J, Leon, Martin B, Thourani, Vinod H, Makkar, Raj, Kodali, Susheel K, Russo, Mark, Kapadia, Samir R, Malaisrie, S. Chris, Cohen, David J, Pibarot, Philippe, Leipsic, Jonathon, Hahn, Rebecca T, Blanke, Philipp, Williams, Mathew R, McCabe, James M, Brown, David L, Babaliaros, Vasilis, Goldman, Scott, Szeto, Wilson Y, Genereux, Philippe, Pershad, Ashish, Pocock, Stuart J, Alu, Maria C, Webb, John G, Smith, Craig R

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Genetic ablation of the t-SNARE SNAP-25 distinguishes mechanisms of neuroexocytosis von Wilson, Michael C, Washbourne, Philip, Thompson, Peter M, Carta, Mario, Costa, Edmar T, Mathews, James R, Lopez-Benditó, Guillermina, Molnár, Zoltán, Becher, Mark W, Valenzuela, C. Fernando, Partridge, L. Donald

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Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study von Cleynen, Isabelle, PhD, Boucher, Gabrielle, MSc, Jostins, Luke, PhD, Schumm, L Philip, MA, Zeissig, Sebastian, PhD, Ahmad, Tariq, PhD, Andersen, Vibeke, Prof, Andrews, Jane M, Prof, Annese, Vito, MD, Brand, Stephan, Prof, Brant, Steven R, MD, Cho, Judy H, Prof, Daly, Mark J, Prof, Dubinsky, Marla, MD, Duerr, Richard H, Prof, Ferguson, Lynnette R, Prof, Franke, Andre, Prof, Gearry, Richard B, Prof, Goyette, Philippe, PhD, Hakonarson, Hakon, Prof, Halfvarson, Jonas, MD, Hov, Johannes R, PhD, Huang, Hailang, PhD, Kennedy, Nicholas A, PhD, Kupcinskas, Limas, Prof, Lawrance, Ian C, Prof, Lee, James C, PhD, Satsangi, Jack, Prof, Schreiber, Stephan, Prof, Théâtre, Emilie, PhD, van der Meulen-de Jong, Andrea E, MD, Weersma, Rinse K, Prof, Wilson, David C, Prof, Parkes, Miles, PhD, Vermeire, Severine, Prof, Rioux, John D, Prof, Mansfield, John, MD, Silverberg, Mark S, PhD, Radford-Smith, Graham, PhD, McGovern, Dermot P B, Prof, Barrett, Jeffrey C, Dr, Lees, Charlie W, Dr

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Effects of Alteplase for Acute Stroke on the Distribution of Functional Outcomes: A Pooled Analysis of 9 Trials von Lees, Kennedy R, Emberson, Jonathan, Blackwell, Lisa, Bluhmki, Erich, Davis, Stephen M, Donnan, Geoffrey A, Grotta, James C, Kaste, Markku, von Kummer, Rüdiger, Lansberg, Maarten G, Lindley, Richard I, Lyden, Patrick, Murray, Gordon D, Sandercock, Peter A.G, Toni, Danilo, Toyoda, Kazunori, Wardlaw, Joanna M, Whiteley, William N, Baigent, Colin, Hacke, Werner, Howard, George

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Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis von Vujkovic, Marijana, Keaton, Jacob M., Lynch, Julie A., Miller, Donald R., Zhou, Jin, Tcheandjieu, Catherine, Huffman, Jennifer E., Assimes, Themistocles L., Lorenz, Kimberly, Zhu, Xiang, Hilliard, Austin T., Judy, Renae L., Huang, Jie, Lee, Kyung M., Klarin, Derek, Pyarajan, Saiju, Danesh, John, Melander, Olle, Rasheed, Asif, Mallick, Nadeem H., Hameed, Shahid, Qureshi, Irshad H., Afzal, Muhammad Naeem, Malik, Uzma, Jalal, Anjum, Abbas, Shahid, Sheng, Xin, Gao, Long, Kaestner, Klaus H., Susztak, Katalin, Sun, Yan V., DuVall, Scott L., Cho, Kelly, Lee, Jennifer S., Gaziano, J. Michael, Phillips, Lawrence S., Meigs, James B., Reaven, Peter D., Wilson, Peter W., Edwards, Todd L., Rader, Daniel J., Damrauer, Scott M., O’Donnell, Christopher J., Tsao, Philip S., Chang, Kyong-Mi, Voight, Benjamin F., Saleheen, Danish

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Dementia And Physical Activity (DAPA) trial of moderate to high intensity exercise training for people with dementia: randomised controlled trial von Lamb, Sarah E, Sheehan, Bart, Atherton, Nicky, Nichols, Vivien, Collins, Helen, Mistry, Dipesh, Dosanjh, Sukhdeep, Slowther, Anne Marie, Khan, Iftekhar, Petrou, Stavros, Lall, Ranjit

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Evaluation of Outcomes Among Patients With Traumatic Intracranial Hypertension Treated With Decompressive Craniectomy vs Standard Medical Care at 24 Months: A Secondary Analysis of... von Kolias, Angelos G, Adams, Hadie, Timofeev, Ivan S, Corteen, Elizabeth A, Hossain, Iftakher, Czosnyka, Marek, Timothy, Jake, Anderson, Ian, Bulters, Diederik O, Belli, Antonio, Eynon, C. Andrew, Wadley, John, Mendelow, A. David, Mitchell, Patrick M, Wilson, Mark H, Critchley, Giles, Sahuquillo, Juan, Unterberg, Andreas, Posti, Jussi P, Servadei, Franco, Teasdale, Graham M, Pickard, John D, Menon, David K, Murray, Gordon D, Kirkpatrick, Peter J, Hutchinson, Peter J

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Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries von Kahan, Brennan C., Koulenti, Desponia, Arvaniti, Kostoula, Beavis, Vanessa, Campbell, Douglas, Chan, Matthew, Moreno, Rui, Pearse, Rupert M.

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Characteristics and Outcomes of Individuals With Pre-existing Kidney Disease and COVID-19 Admitted to Intensive Care Units in the United States von Assimon, Magdalene M., Shah, Jatan, Renaghan, Amanda DeMauro, Wilson, F. Perry, Neyra, Javier A., Anand, Shuchi, Edmonston, Daniel, Walther, Carl P., Anumudu, Samaya J., Arunthamakun, Justin, McCullough, Peter A., Nguyen, Thuy-Duyen, Krajewski, Megan L., Shankar, Sidharth, Pannu, Ameeka, Waikar, Sushrut S., Athavale, Ambarish M., Green, Adam, Schorr, Christa A., Shehata, Alexandre M., Allusson, Valerie, Mehta, Bijal, Williams, Aquino, Altman, Deena R., Corona-Villalobos, Celia P., Mallappallil, Mary C., Nguyen, H. Bryant, Sirganagari, Dheeraj Reddy, Guru, Pramod K., Zhou, Yan, Rodriguez, Jesus, Shah, Jatan A., Mocerino, Ryan, Azzi, Yorg, Fisher, Molly, Sedaliu, Kaltrina, Kumar, Neelja, Chang, Michael, Plataki, Maria, Alvarez-Mulett, Sergio L., Krishnan, Jamuna, Macina, Ashley, Wu, Benjamin, Modersitzki, Frank, Martinez, Carlos, Hodakowski, Alexander J., Velez, Juan Carlos Q., Avasare, Rupali S., Gupta, Shruti, Sise, Meghan E., Sharma, Shreyak, Singh, Harkarandeep, Shaukat, Tanveer, Kamal, Omer, Boateng, Jeffery O., Lee, Meghan, Li, Jiahua, Bickley, Laura, Byun, John J., Sutherland, Anne K., Finkel, Diana G., Arikapudi, Sowminya, Cangialosi, Peter, Liotta, Mark, Vatson, Jayanth S., Levitt, Joseph E., Burnham, Ellen L., Rashidi, Arash, Latta, Laura, Tolwani, Ashita, Adams, Jason Y., Beutler, Rebecca M., Monica, Santa, Macedo, Etienne, Rhee, Harin, Liu, Kathleen D., Koyner, Jay L., Chaaban, Nourhan, Au, Elizabeth H., Sharma, Jill H., De La Zerda, David, Azam, Tariq U., Perry, Danny, Bitar, Abbas, Donnelly, John P., Tugman, Matthew J., Miano, Todd A., Bansal, Amar D., Ernecoff, Natalie C., Kapoor, Sanjana, Chen, Huiwen, Hedayati, S. Susan, Shastri, Shani, Willett, Duwayne L., Bhatraju, Pavan K., Semler, Matthew W., Vijayan, Anitha, Li, Tingting, Jose, Aju, Gupta, Sanjeev

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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs von Lee, S Hong, Ripke, Stephan, Neale, Benjamin M, Faraone, Stephen V, Purcell, Shaun M, Perlis, Roy H, Mowry, Bryan J, Thapar, Anita, Goddard, Michael E, Witte, John S, Absher, Devin, Agartz, Ingrid, Akil, Huda, Amin, Farooq, Andreassen, Ole A, Anjorin, Adebayo, Anney, Richard, Anttila, Verneri, Arking, Dan E, Asherson, Philip, Azevedo, Maria H, Backlund, Lena, Badner, Judith A, Bailey, Anthony J, Banaschewski, Tobias, Barchas, Jack D, Barnes, Michael R, Barrett, Thomas B, Bass, Nicholas, Battaglia, Agatino, Bauer, Michael, Bayés, Mònica, Bellivier, Frank, Bergen, Sarah E, Berrettini, Wade, Betancur, Catalina, Bettecken, Thomas, Biederman, Joseph, Binder, Elisabeth B, Black, Donald W, Blackwood, Douglas H R, Bloss, Cinnamon S, Boehnke, Michael, Boomsma, Dorret I, Breen, Gerome, Breuer, René, Bruggeman, Richard, Cormican, Paul, Buccola, Nancy G, Buitelaar, Jan K, Bunney, William E, Buxbaum, Joseph D, Byerley, William F, Byrne, Enda M, Caesar, Sian, Cahn, Wiepke, Cantor, Rita M, Casas, Miguel, Chakravarti, Aravinda, Chambert, Kimberly, Choudhury, Khalid, Cichon, Sven, Cloninger, C Robert, Collier, David A, Cook, Edwin H, Coon, Hilary, Cormand, Bru, Corvin, Aiden, Coryell, William H, Craig, David W, Craig, Ian W, Crosbie, Jennifer, Cuccaro, Michael L, Curtis, David, Czamara, Darina, Datta, Susmita, Dawson, Geraldine, Day, Richard, De Geus, Eco J, Degenhardt, Franziska, Djurovic, Srdjan, Donohoe, Gary J, Doyle, Alysa E, Duan, Jubao, Dudbridge, Frank, Duketis, Eftichia, Ebstein, Richard P, Edenberg, Howard J, Elia, Josephine, Ennis, Sean, Etain, Bruno, Fanous, Ayman, Farmer, Anne E, Ferrier, I Nicol, Flickinger, Matthew, Fombonne, Eric, Foroud, Tatiana, Frank, Josef, Franke, Barbara, Fraser, Christine

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Extracorporeal membrane oxygenation in patients with severe respiratory failure from COVID-19 von Shaefi, Shahzad, Brenner, Samantha K., Gupta, Shruti, O’Gara, Brian P., Krajewski, Megan L., Charytan, David M., Chaudhry, Sobaata, Mirza, Sara H., Peev, Vasil, Anderson, Mark, Bansal, Anip, Hayek, Salim S., Srivastava, Anand, Mathews, Kusum S., Johns, Tanya S., Leonberg-Yoo, Amanda, Green, Adam, Arunthamakun, Justin, Wille, Keith M., Shaukat, Tanveer, Singh, Harkarandeep, Admon, Andrew J., Semler, Matthew W., Hernán, Miguel A., Mueller, Ariel L., Wang, Wei, Leaf, David E.

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Lung adenocarcinoma promotion by air pollutants von Hill, William, Lim, Emilia L., Weeden, Clare E., Lee, Claudia, Augustine, Marcellus, Chen, Kezhong, Kuan, Feng-Che, Marongiu, Fabio, Evans, Edward J., Moore, David A., Rodrigues, Felipe S., Pich, Oriol, Bakker, Bjorn, Cha, Hongui, Myers, Renelle, van Maldegem, Febe, Boumelha, Jesse, Veeriah, Selvaraju, Rowan, Andrew, Naceur-Lombardelli, Cristina, Karasaki, Takahiro, Sivakumar, Monica, De, Swapnanil, Caswell, Deborah R., Nagano, Ai, Black, James R. M., Martínez-Ruiz, Carlos, Ryu, Min Hyung, Huff, Ryan D., Li, Shijia, Favé, Marie-Julie, Magness, Alastair, Suárez-Bonnet, Alejandro, Priestnall, Simon L., Lüchtenborg, Margreet, Lavelle, Katrina, Pethick, Joanna, Hardy, Steven, McRonald, Fiona E., Lin, Meng-Hung, Troccoli, Clara I., Ghosh, Moumita, Miller, York E., Merrick, Daniel T., Keith, Robert L., Al Bakir, Maise, Bailey, Chris, Hill, Mark S., Saal, Lao H., Chen, Yilun, George, Anthony M., Abbosh, Christopher, Kanu, Nnennaya, Lee, Se-Hoon, McGranahan, Nicholas, Berg, Christine D., Sasieni, Peter, Houlston, Richard, Turnbull, Clare, Lam, Stephen, Awadalla, Philip, Grönroos, Eva, Downward, Julian, Jacks, Tyler, Carlsten, Christopher, Malanchi, Ilaria, Hackshaw, Allan, Litchfield, Kevin, DeGregori, James, Jamal-Hanjani, Mariam, Swanton, Charles

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Peri‐operative administration of tranexamic acid in lower limb arthroplasty: a multicentre, prospective cohort study von Fennelly, J., Claireaux, H., Carr, A. J., Murphy, M., Kendrick, B. J., Palmer, A. J. R., Sharma, P., Osei‐Bonsu, P. K., Ashcroft, G., Baigent, T., Shirland, E., Espey, R., Stokes, M., Liew, I., Dhawal, A., Watchorn, D., Lum, J., Qureshi, M., Khaled, A. S., Rogers, S., Haywood‐Alexander, B., Sheikh, G., Mahapatra, P., Chicco, M., Atherton, T., Sinha, P., Oliver, E., Stedman, T., Gadd, R., Kutuzov, V., Sattar, M., Hassan, A., Lau, B., Doshi, A., Tan, G., Baskaran, D., Hari Sunil Kumar, K., Agarwal, R., Horner, M., Gwyn, R., Masud, S., Beaumont, O., Lebe, M., Dawson‐Bowling, S., Nolan, D., Jordan, C., Deshpande, G., Gould, A., Kilbane, L., Crowther, I., Ingoe, H., Naisbitt, A., Gourbault, L., Goh, E. L., Elbashir, M., Modi, N., Archer, J., Ismael, S., O'Brien, H., McCormick, M., Koh, N. P., Lloyd, T., Ikram, A., Peake, J., Yoong, A., Rye, D. S., Newman, M., Naraen, A., Myatt, D., Kohli, S., Culverhouse‐Mathews, M., Haynes, S., Boden, H., Purmah, A., Shenoy, R., Raja, S., Donovan, R., Yeomans, D., Ritchie, D., Aladwan, R., Hughes, K., Unsworth, R., Cooke, R., Barrow, J., Michael, K, Drysdale, H., Wilson, H., Jones, R., Dass, D., Liaw, F., Ramavath, A. L., Telfer, R., Nachev, K., Lawrence, H., Garg, V., Shenoy, P., Lacey, A., Byrom, I., Simons, M., Cheyne, N.

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Remote Ischemic Preconditioning and Outcomes of Cardiac Surgery von Hausenloy, Derek J, Candilio, Luciano, Evans, Richard, Ariti, Cono, Jenkins, David P, Kolvekar, Shyam, Knight, Rosemary, Kunst, Gudrun, Laing, Christopher, Nicholas, Jennifer, Pepper, John, Robertson, Steven, Xenou, Maria, Clayton, Tim, Yellon, Derek M

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