Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes von Goodwin, Nicole C, Ding, Zhi-Ming, Harrison, Bryce A, Strobel, Eric D, Harris, Angela L, Smith, Melinda, Thompson, Andrea Y, Xiong, Wendy, Mseeh, Faika, Bruce, Debra J, Diaz, Damaris, Gopinathan, Suma, Li, Ling, O’Neill, Emily, Thiel, Mary, Wilson, Alan G. E, Carson, Kenneth G, Powell, David R, Rawlins, David B

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Discovery and Development of LX7101, a Dual LIM-Kinase and ROCK Inhibitor for the Treatment of Glaucoma von Harrison, Bryce A, Almstead, Zheng Y, Burgoon, Hugh, Gardyan, Michael, Goodwin, Nicole C, Healy, Jason, Liu, Ying, Mabon, Ross, Marinelli, Brett, Samala, Lakshman, Zhang, Yulian, Stouch, Terry R, Whitlock, N. Andrew, Gopinathan, Suma, McKnight, Beth, Wang, Shuli, Patel, Nita, Wilson, Alan G. E, Hamman, Brian D, Rice, Dennis S, Rawlins, David B

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Novel Class of LIM-Kinase 2 Inhibitors for the Treatment of Ocular Hypertension and Associated Glaucoma von Harrison, Bryce A, Whitlock, N. Andrew, Voronkov, Michael V, Almstead, Zheng Y, Gu, Kun-jian, Mabon, Ross, Gardyan, Michael, Hamman, Brian D, Allen, Jason, Gopinathan, Suma, McKnight, Beth, Crist, Mike, Zhang, Yulian, Liu, Ying, Courtney, Lawrence F, Key, Billie, Zhou, Julia, Patel, Nita, Yates, Phil W, Liu, Qingyun, Wilson, Alan G. E, Kimball, S. David, Crosson, Craig E, Rice, Dennis S, Rawlins, David B

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Early Toxicology Signal Generation in the Mouse von Kramer, Jeffrey A., O’Neill, Emily, Phillips, Megan E., Bruce, Debra, Smith, Traci, Albright, Melinda M., Bellum, Sairam, Gopinathan, Suma, Heydorn, William E., Liu, Xuemei, Nouraldeen, Amr, Payne, Bobby Joe, Read, Robert, Vogel, Peter, Yu, Xiang-Qing, Wilson, Alan G. E.

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Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase von Tarver, James E., Pabba, Praveen K., Barbosa, Joseph, Han, Qiang, Gardyan, Michael W., Brommage, Robert, Thompson, Andrea Y., Schmidt, James M., Wilson, Alan G.E., He, Wei, Lombardo, Victoria K., Carson, Kenneth G.

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About electron transfer over long distances with tunable sub/supersonic velocities von Velarde, M. G., Chetverikov, A. P., Launay, J.-P., Ebeling, W., Wilson, E. G.

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4H-Thieno[3,2-c]chromene based inhibitors of Notum Pectinacetylesterase von Han, Qiang, Pabba, Praveen K., Barbosa, Joseph, Mabon, Ross, Healy, Jason P., Gardyan, Michael W., Terranova, Kristen M., Brommage, Robert, Thompson, Andrea Y., Schmidt, James M., Wilson, Alan G.E., Xu, Xiaolian, Tarver, James E., Carson, Kenneth G.

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Novel l-Xylose Derivatives as Selective Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitors for the Treatment of Type 2 Diabetes von Goodwin, Nicole C, Mabon, Ross, Harrison, Bryce A, Shadoan, Melanie K, Almstead, Zheng Y, Xie, Yiling, Healy, Jason, Buhring, Lindsey M, DaCosta, Christopher M, Bardenhagen, Jennifer, Mseeh, Faika, Liu, Qingyun, Nouraldeen, Amr, Wilson, Alan G. E, Kimball, S. David, Powell, David R, Rawlins, David B

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Influence of Molecular Flexibility and Polar Surface Area Metrics on Oral Bioavailability in the Rat von Lu, Jing J, Crimin, Kimberly, Goodwin, Jay T, Crivori, Patrizia, Orrenius, Christian, Xing, Li, Tandler, Peter J, Vidmar, Thomas J, Amore, Benny M, Wilson, Alan G. E, Stouten, Pieter F. W, Burton, Philip S

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Genotoxic Potential of Glyphosate Formulations: Mode-of-Action Investigations von Heydens, William F, Healy, Charles E, Hotz, Kathy J, Kier, Larry D, Martens, Mark A, Wilson, Alan G. E, Farmer, Donna R

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On the electron transport in polydiacetylene crystals and derivatives von Velarde, M. G., Chetverikov, A. P., Ebeling, W., Wilson, E. G., Donovan, K. J.

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Iris small break loca phenomena identification and ranking table (PIRT) von Larson, T.K., Moody, F.J., Wilson, G.E., Brown, W.L., Frepoli, C., Hartz, J., Woods, B.G., Oriani, L.

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Investigation of the surface morphology of thermally evaporated thin gold films on mica, glass, silicon and calcium fluoride substrates by scanning tunneling microscopy von Semaltianos, N.G, Wilson, E.G

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A study of anal intraepithelial neoplasia in HIV positive homosexual men von Lacey, H B, Wilson, G E, Tilston, P, Wilkins, E G, Bailey, A S, Corbitt, G, Green, P M

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Calcitriol modulation of cardiac contractile performance via protein kinase C von Green, John J., Robinson, Dustin A., Wilson, G.E., Simpson, Robert U., Westfall, Margaret V.

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Cross-Polarized Magic-Angle Spinning (sup13)C Nuclear Magnetic Resonance Spectroscopic Characterization of Soil Organic Matter Relative to Culturable Bacterial Species Composition... von Boehm, M J, Wu, T, Stone, A G, Kraakman, B, Iannotti, D A, Wilson, G E, Madden, L V, Hoitink, H

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Evaluation of a basic physiologically based pharmacokinetic model for simulating the first-time-in-animal study von Germani, Massimiliano, Crivori, Patrizia, Rocchetti, Maurizio, Burton, Philip S., Wilson, Alan G.E., Smith, Mark E., Poggesi, Italo

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Minichromosome maintenance (Mcm) proteins, cyclin B1 and D1, phosphohistone H3 and in situ DNA replication for functional analysis of vulval intraepithelial neoplasia von Davidson, E J, Morris, L S, Scott, I S, Rushbrook, S M, Bird, K, Laskey, R A, Wilson, G E, Kitchener, H C, Coleman, N, Stern, P L

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Development of a highthroughput yeast-based assay for detection of metabolically activated genotoxins von Liu, Xuemei, Kramer, Jeffrey A., Swaffield, Jonathan C., Hu, Yi, Chai, Guixuan, Wilson, Alan G.E.

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Treatment of large airway obstruction in lung cancer using expandable metal stents inserted under direct vision via the fibreoptic bronchoscope von Wilson, G E, Walshaw, M J, Hind, C R

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