P10 Utrophin modulators to treat Duchenne Muscular Dystrophy (DMD): Future clinical trial plans for SMT C1100 and biomarker development programme von Tinsley, J.M, Bracchi, A, Wilson, F.X, Horne, G, Robinson, N, Fairclough, R.J, Davies, K.E

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P.13.14 Future clinical and biomarker development for SMTC1100, the first utrophin modulator to enter clinical trials for Duchenne Muscular Dystrophy (DMD) von Tinsley, J.M, Robinson, N, Wilson, F.X, Horne, G, Fairclough, R.J, Davies, K.E

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G.P.89 von Fairclough, R.J, Guiraud, S, Squire, S.E, Babbs, A, Edward, B, Shah, N, Bracchi, A, Wilson, F.X, Horne, G, Robinson, N, Araujo, N, Hewings, D.S, Vuorinen, A, Davies, S.G, Wynne, G.M, Russell, A.J, Tinsley, J, Davies, K.E

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G.P.89: New orally available compounds which modulate utrophin expression for the therapy of Duchenne muscular dystrophy (DMD) von Fairclough, R.J., Guiraud, S., Squire, S.E., Babbs, A., Edward, B., Shah, N., Bracchi, A., Wilson, F.X., Horne, G., Robinson, N., Araujo, N., Hewings, D.S., Vuorinen, A., Davies, S.G., Wynne, G.M., Russell, A.J., Tinsley, J., Davies, K.E.

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Synthesis of the potent antiviral oxetane nucleoside epinoroxetanocin from D-lyxonolactone von Wang, Y., Fleet, G.W.J., Storer, R., Myers, P.L., Wallis, C.J., Doherty, O., Watkin, D.J., Vogt, K., Witty, D.R., Wilson, F.X., Peach, J.M.

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The identification of α-ketoamides as potent inhibitors of hepatitis C virus NS3-4A proteinase von BENNETT, J. M, CAMPBELL, A. D, KAY, P. B, O'BRIEN, M. A, KING-UNDERWOOD, J, RAYNHAM, T. M, WILKINSON, C. S, WILKINSON, T. C. I, WILSON, F. X, CAMPBELL, A. J, CARR, M. G, DUNSDON, R. M, GREENING, J. R, HURST, D. N, JENNINGS, N. S, JONES, P. S, JORDAN, S

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Design and synthesis of hepatitis C NS3 proteinase inhibitors von Wilson, F.X., Bryson, A., Harris, S., Jones, P.S., Kingston, S.T., Sutton, B., Wilkinson, T.C.I.W.

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Ring contraction of 2-o-trifluoromethanesulphonates of α-hydroxy-γ-lactones to oxetane carboxylic esters von Witty, D.R, Fleet, G.W.J, Vogt, K, Wilson, F.X, Wang, Y, Storer, R, Myers, P.L, Wallis, C.J

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Oxetane nucleosides with fluorine and azide substitutents: nucleophilic displacements on an oxetane ring von Wang, Y., Fleet, G.W.J., Wilson, F.X., Storer, R., Wallis, C.J., Doherty, O., Watkin, D.J., Vogt, K., Witty, D.R., Peach, J.M.

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Synthesis of oxetanocin von Wilson, F.X., Fleet, G.W.J., Vogt, K., Wang, Y., Witty, D.R., Choi, S., Storer, R., Myers, P.L., Wallis, C.J.

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Ring contraction of 3-deoxy-2-O-trifluoromethanesulphonates of α-hydroxy-γ-lactones to oxetanes von Witty, D.R., Fleet, G.W.J., Choi, S., Vogt, K., Wilson, F.X., Wang, Y., Storer, R., Myers, P.L., Wallis, C.J.

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Synthesis of the oxetane nucleosides α- an β-noroxetanocin von Wilson, F.X., Fleet, G.W.J., Witty, D.R., Vogt, K., Wang, Y., Storer, R., Myers, P.L., Wallis, C.J.

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Attempted ring contraction of α-triflates of 3-azido- and 3-fluoro-γ-lactones to oxetanes von Elliott, R.P., Fleet, G.W.J., Vogt, K., Wilson, F.X., Wang, Y., Witty, D.R., Storer, R., Myers, P.L., Wallis, C.J.

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The nuclear matrix protein CIZ1 facilitates localization of Xist RNA to the inactive X-chromosome territory von Ridings-Figueroa, Rebeca, Stewart, Emma R, Nesterova, Tatyana B, Coker, Heather, Pintacuda, Greta, Godwin, Jonathan, Wilson, Rose, Haslam, Aidan, Lilley, Fred, Ruigrok, Renate, Bageghni, Sumia A, Albadrani, Ghadeer, Mansfield, William, Roulson, Jo-An, Brockdorff, Neil, Ainscough, Justin F X, Coverley, Dawn

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Constitutively Active TRPC Channels of Adipocytes Confer a Mechanism for Sensing Dietary Fatty Acids and Regulating Adiponectin von Sukumar, Piruthivi, Sedo, Alicia, Li, Jing, Wilson, Lesley A, OʼRegan, David, Lippiat, Jonathan D, Porter, Karen E, Kearney, Mark T, Ainscough, Justin F.X, Beech, David J

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Piezo1 integration of vascular architecture with physiological force von Li, Jing, Hou, Bing, Tumova, Sarka, Muraki, Katsuhiko, Bruns, Alexander, Ludlow, Melanie J., Sedo, Alicia, Hyman, Adam J., McKeown, Lynn, Young, Richard S., Yuldasheva, Nadira Y., Majeed, Yasser, Wilson, Lesley A., Rode, Baptiste, Bailey, Marc A., Kim, Hyejeong R., Fu, Zhaojun, Carter, Deborah A. L., Bilton, Jan, Imrie, Helen, Ajuh, Paul, Dear, T. Neil, Cubbon, Richard M., Kearney, Mark T., Prasad, K. Raj, Evans, Paul C., Ainscough, Justin F. X., Beech, David J.

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Epigenetic instability caused by absence of CIZ1 drives transformation during quiescence cycles von Dobbs, Olivia G, Wilson, Rosemary H C, Newling, Katherine, Ainscough, Justin F-X, Coverley, Dawn

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Employment associated with violence, transactional sex, and low relationship power (HPTN068) von Luetke, M., Ludema, C., Mayo-Wilson, L. Jennings, Herbenick, D., Gómez-Olivé, F.X., Pettifor, A., Rosenberg, M.

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A cooperative interaction between LPHN3 and 11q doubles the risk for ADHD von Jain, M, Vélez, J I, Acosta, M T, Palacio, L G, Balog, J, Roessler, E, Pineda, D, Londoño, A C, Palacio, J D, Arbelaez, A, Lopera, F, Elia, J, Hakonarson, H, Seitz, C, Freitag, C M, Palmason, H, Meyer, J, Romanos, M, Walitza, S, Hemminger, U, Warnke, A, Romanos, J, Renner, T, Jacob, C, Lesch, K-P, Swanson, J, Castellanos, F X, Bailey-Wilson, J E, Arcos-Burgos, M, Muenke, M

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PUK10 Cost Savings of Peritoneal Dialysis Versus Conventional in-Center Hemodialysis Under Medicare Bundled Payment System von Liu, F.X, Inglese, G, Leipold, R, Patterson, J, Abbott, G, Wilson, D

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