Clinical Evolution of Epithelial-Mesenchymal Transition in Human Carcinomas von Navas, Tony, Kinders, Robert J., Lawrence, Scott M., Ferry-Galow, Katherine, Borgel, Suzanne, Hollingshead, Melinda G., Srivastava, Apurva K., Alcoser, Sergio Y., Makhlouf, Hala R., Chuaqui, Rodrigo, Wilsker, Deborah F., Konate, Mariam M., Miller, Sarah B., Voth, Andrea Regier, Chen, Li, Vilimas, Tomas, Subramanian, Jyothi, Rubinstein, Lawrence, Kummar, Shivaani, Chen, Alice P., Bottaro, Donald P., Doroshow, James H., Parchment, Ralph E.

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Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control von Wilsker, Deborah, Petermann, Eva, Helleday, Thomas, Bunz, Fred

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Atezolizumab for Advanced Alveolar Soft Part Sarcoma von Chen, Alice P., Sharon, Elad, O’Sullivan-Coyne, Geraldine, Moore, Nancy, Foster, Jared C., Hu, James S., Van Tine, Brian A., Conley, Anthony P., Read, William L., Riedel, Richard F., Burgess, Melissa A., Glod, John, Davis, Elizabeth J., Merriam, Priscilla, Naqash, Abdul R., Fino, Kristin K., Miller, Brandon L., Wilsker, Deborah F., Begum, Asma, Ferry-Galow, Katherine V., Deshpande, Hari A., Schwartz, Gary K., Ladle, Brian H., Okuno, Scott H., Beck, Jill C., Chen, James L., Takebe, Naoko, Fogli, Laura K., Rosenberger, Christina L., Parchment, Ralph E., Doroshow, James H.

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Association of changes in expression of HDAC and SIRT genes after drug treatment with cancer cell line sensitivity to kinase inhibitors von Krushkal, Julia, Zhao, Yingdong, Roney, Kyle, Zhu, Weimin, Brooks, Alan, Wilsker, Deborah, Parchment, Ralph E, McShane, Lisa M, Doroshow, James H

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Evaluation of Pharmacodynamic Responses to Cancer Therapeutic Agents Using DNA Damage Markers von Wilsker, Deborah F, Barrett, Allison M, Dull, Angie B, Lawrence, Scott M, Hollingshead, Melinda G, Chen, Alice, Kummar, Shivaani, Parchment, Ralph E, Doroshow, James H, Kinders, Robert J

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Loss of ataxia telangiectasia mutated– and Rad3-related function potentiates the effects of chemotherapeutic drugs on cancer cell survival von Wilsker, Deborah, Bunz, Fred

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ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide von El Touny, Lara H., Hose, Curtis, Connelly, John, Harris, Erik, Monks, Anne, Dull, Angie B., Wilsker, Deborah F., Hollingshead, Melinda G., Gottholm-Ahalt, Michelle, Alcoser, Sergio Y., Mullendore, Michael E., Parchment, Ralph E., Doroshow, James H., Teicher, Beverly A., Rapisarda, Annamaria

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The Root Causes of Pharmacodynamic Assay Failure von Ferry-Galow, Katherine V., PhD, Makhlouf, Hala R., MD, PhD, Wilsker, Deborah F., PhD, Lawrence, Scott M, Pfister, Thomas D., PhD, Marrero, Allison M., PhD, Bigelow, Kristina M, Yutzy, William H, Ji, Jiuping J., PhD, Butcher, Donna O, Gouker, Brad A, Kummar, Shivaani, MD, Chen, Alice P., MD, Kinders, Robert J., PhD, Parchment, Ralph E., PhD, Doroshow, James H., MD

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Translating Pharmacodynamic Biomarkers from Bench to Bedside: Analytical Validation and Fit-for-Purpose Studies to Qualify Multiplex Immunofluorescent Assays for use on Clinical Co... von Marrero, Allison, PhD, Lawrence, Scott, PhD, Wilsker, Deborah, PhD, Voth, Andrea Regier, Ph.D, Kinders, Robert, PhD

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Two related ARID family proteins are alternative subunits of human SWI/SNF complexes von Wang, Xiaomei, Nagl, Norman G, Wilsker, Deborah, Van Scoy, Michael, Pacchione, Stephen, Yaciuk, Peter, Dallas, Peter B, Moran, Elizabeth

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Chk1 suppresses bypass of mitosis and tetraploidization in p53-deficient cancer cells von Wilsker, Deborah, Chung, Jon H., Bunz, Fred

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Chk1 phosphorylation during mitosis: A new role for a master regulator von Wilsker, Deborah, Bunz, Fred

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Phase I Study of Single-Agent AZD1775 (MK-1775), a Wee1 Kinase Inhibitor, in Patients With Refractory Solid Tumors von Do, Khanh, Wilsker, Deborah, Ji, Jiuping, Zlott, Jennifer, Freshwater, Tomoko, Kinders, Robert J, Collins, Jerry, Chen, Alice P, Doroshow, James H, Kummar, Shivaani

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The Human SWI-SNF Complex Protein p270 Is an ARID Family Member with Non-Sequence-Specific DNA Binding Activity von Dallas, Peter B., Pacchione, Stephen, Wilsker, Deborah, Bowrin, Valerie, Kobayashi, Ryuji, Moran, Elizabeth

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The National Cancer Institute ALMANAC: A Comprehensive Screening Resource for the Detection of Anticancer Drug Pairs with Enhanced Therapeutic Activity von Holbeck, Susan L, Camalier, Richard, Crowell, James A, Govindharajulu, Jeevan Prasaad, Hollingshead, Melinda, Anderson, Lawrence W, Polley, Eric, Rubinstein, Larry, Srivastava, Apurva, Wilsker, Deborah, Collins, Jerry M, Doroshow, James H

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Safety, Antitumor Activity, and Biomarker Analysis in a Phase I Trial of the Once-daily Wee1 Inhibitor Adavosertib (AZD1775) in Patients with Advanced Solid Tumors von Takebe, Naoko, Naqash, Abdul Rafeh, Coyne, Geraldine O'Sullivan, Kummar, Shivaani, Do, Khanh, Bruns, Ashley, Juwara, Lamin, Zlott, Jennifer, Rubinstein, Larry, Piekarz, Richard, Sharon, Elad, Streicher, Howard, Mittra, Arjun, Miller, Sarah B., Ji, Jiuping, Wilsker, Deborah, Kinders, Robert J., Parchment, Ralph E., Chen, Li, Chang, Ting-Chia, Das, Biswajit, Mugundu, Ganesh, Doroshow, James H., Chen, Alice P.

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Expression of Genes Encoding Chromatin Regulatory Factors in Developing Rhesus Monkey Oocytes and Preimplantation Stage Embryos: Possible Roles in Genome Activation von Zheng, Ping, Patel, Bela, McMenamin, Malgorzata, Paprocki, Ann Marie, Schramm, R Dee, Nagl, Jr, Norman G, Wilsker, Deborah, Wang, Xiaomei, Moran, Elizabeth, Latham, Keith E

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Phase 1 study of indenoisoquinoline LMP744 in adults with relapsed solid tumors and lymphomas von Ko, Brian, Chen, Alice P., Kummar, Shivaani, Hogu, Murielle, Rubinstein, Larry V., Takebe, Naoko, Piekarz, Richard, Sharon, Elad, Beumer, Jan Hendrik, Wilsker, Deborah, Ketchum, Donna, Ferry-Galow, Katherine V., Parchment, Ralph E., Holleran, Julianne L., Deppas, Joshua J., Collins, Jerry M., Johnson, Barry C., Ivy, S. Percy, Doroshow, James H., O'Sullivan Coyne, Geraldine Helen

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Phase 2 trial of TRC102 (methoxyamine HCl) with temozolomide (TMZ) in patients with granulosa cell ovarian cancer von Shin, Sarah, O'Sullivan Coyne, Geraldine Helen, Zlott, Jennifer, Salkeni, Mohamad Adham, Takebe, Naoko, Ma, Ning, Rubinstein, Larry V., Piekarz, Richard, Wilsker, Deborah, Ferry-Galow, Katherine V., Miller, Brandon, Parchment, Ralph E., Jiwani, Shahanawaz, Juwara, Lamin, Voth, Andrea, Doroshow, James H., Chen, Alice P.

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Abstract CT115: Phase I trial of the triplet berzosertib (M6620, VX-970), veliparib and cisplatin (BVP) in patients with advanced solid tumors von Coyne, Geraldine O'Sullivan, Do, Khanh T., Kummar, Shivaani, Takebe, Naoko, Piha-Paul, Sarina, Piekarz, Richard, Wilsker, Deborah, Miller, Brandon, Ferry-Galow, Katherine, Parchment, Ralph, DNP, Lamin Juwara, Ong, Mary Jane, Mittra, Arjun, Doroshow, James H., Chen, Alice P.

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